PANTHER Gene Information

Gene Symbol(s):

GLS2

Organism:

Canis lupus familiaris

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Gene Name:

glutaminase

Gene ID:

ENSCAFG00845008418.1

Protein ID:

A0A8I3N750

Persistent Id:

PTN000284017

Alternate Ids:

A0A8I3N750_CANLF(UniProtKB-ID)	XP_003431516(refSeq)
ENSCAFG00845008418(Ensembl)	345776645(GI)
ENSCAFT00845014862(Ensembl_TRS)	A0A8I3N750(Synonym)
100686499(GeneID)	ENSCAFP00845011518(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	GLUTAMINASE (PTHR12544)
PANTHER Subfamily:	GLUTAMINASE LIVER ISOFORM, MITOCHONDRIAL (PTHR12544:SF33)
PANTHER GO-slim Molecular Function:	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
PANTHER GO-slim Biological Process:	glutamate metabolic process L-amino acid biosynthetic process proteinogenic amino acid biosynthetic process amino acid catabolic process
PANTHER GO-slim Cellular Component:
PANTHER protein class:	hydrolase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	glutaminase activity
GO BP Complete:	reactive oxygen species metabolic process, glutamate biosynthetic process, glutamine metabolic process, regulation of apoptotic process, glutamine catabolic process
GO CC Complete:	mitochondrion

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Gene expression (Transcription), Generic Transcription Pathway, Metabolism of amino acids and derivatives, TP53 Regulates Metabolic Genes, Neuronal System, Transcriptional Regulation by TP53, Glutamate Neurotransmitter Release Cycle, RNA Polymerase II Transcription, Transmission across Chemical Synapses, Metabolism, Glutamate and glutamine metabolism, Neurotransmitter release cycle

Orthologs

ID	Organism	Type
HUMAN\|HGNC=29570\|UniProtKB=Q9UI32	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000005101.5\|UniProtKB=H2Q692	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000016580.3\|UniProtKB=G3RKB6	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000000860.4\|UniProtKB=F7H7H2	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2143539\|UniProtKB=Q571F8	Mus musculus	LDO
RAT\|RGD=620359\|UniProtKB=P28492	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000009284.6\|UniProtKB=E1BHZ6	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000000401.4\|UniProtKB=F1SLB4	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000008933.3\|UniProtKB=F6YR42	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000012027.6\|UniProtKB=M3WG75	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000021156.4\|UniProtKB=F6QBQ6	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000043788.1\|UniProtKB=A0A6I8PJ15	Ornithorhynchus anatinus	LDO
ANOCA\|Ensembl=ENSACAG00000016563.4\|UniProtKB=G1KSU1	Anolis carolinensis	LDO
XENLA\|Gene=gls2.L\|UniProtKB=A0A1L8HHZ0	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-985276\|UniProtKB=A0A6I8SMG3	Xenopus tropicalis	LDO
DANRE\|ZFIN=ZDB-GENE-131127-106\|UniProtKB=E7F6N5	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000012927.1\|UniProtKB=W5N5L7	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000012493.2\|UniProtKB=A0A3B3HGS1	Oryzias latipes	LDO
DANRE\|Gene=gls2b\|UniProtKB=A0A8M2BLA3	Danio rerio	O
DANRE\|Gene=gls2a\|UniProtKB=A0A8M9PZE4	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000004907.1\|UniProtKB=W5MBZ8	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000002599.3\|UniProtKB=F6TQT4	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118427272\|UniProtKB=A0A9J7M2F8	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC763697\|UniProtKB=A0A7M7N2H2	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00009271\|UniProtKB=Q93650	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG23724\|UniProtKB=A8WJ54	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00008435\|UniProtKB=Q19013	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG13355\|UniProtKB=A8XHY8	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00007480\|UniProtKB=U4PRW7	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG04264\|UniProtKB=A8WX31	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00108403\|UniProtKB=A0A454XIR8	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00275279\|UniProtKB=A0A2A6BFM3	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00112245\|UniProtKB=A0A2A6B9D9	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00277880\|UniProtKB=A0A2A6B3U5	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0261625\|UniProtKB=Q1RL13	Drosophila melanogaster	LDO
TRICA\|EnsemblGenome=TC004628\|UniProtKB=D6W7V1	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_320441\|UniProtKB=E9GPV0	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW020515\|UniProtKB=B7Q1F5	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG88521\|UniProtKB=T1G736	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG195098\|UniProtKB=T1FWQ9	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG155932\|UniProtKB=T1ELP4	helobdella robusta	LDO
TRIAD\|EnsemblGenome=TriadG61194\|UniProtKB=B3SAA5	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG32107\|UniProtKB=B3SA78	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_27154\|UniProtKB=A9V4G7	Monosiga brevicollis	LDO
TRIV3\|Gene_ORFName=TVAG_134820\|UniProtKB=A2GK90	Trichomonas vaginalis	LDO
STRCO\|Gene_OrderedLocusName=SCO7049\|UniProtKB=P57755	Streptomyces coelicolor	LDO
CLOBH\|Gene_OrderedLocusName=CBO2808\|UniProtKB=A5I5P4	Clostridium botulinum	LDO
BACSU\|EnsemblGenome=BSU_02430\|UniProtKB=O31465	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_3115\|UniProtKB=Q81BN7	Bacillus cereus	O
BACSU\|EnsemblGenome=BSU_14830\|UniProtKB=O07637	Bacillus subtilis	LDO
BACCR\|EnsemblGenome=BC_0481\|UniProtKB=Q81IB3	Bacillus cereus	LDO
FUSNN\|EnsemblGenome=FN1397\|UniProtKB=Q8RDV3	Fusobacterium nucleatum	LDO
BRADU\|EnsemblGenome=BAC50063\|UniProtKB=Q89KV2	Bradyrhizobium diazoefficiens	LDO
BRADU\|EnsemblGenome=BAC49200\|UniProtKB=Q89NA7	Bradyrhizobium diazoefficiens	LDO
SHEON\|Gene_OrderedLocusName=SO_3365\|UniProtKB=Q8EBY0	Shewanella oneidensis	LDO
VIBCH\|EnsemblGenome=VC_0454\|UniProtKB=Q9KUR1	Vibrio cholerae	LDO
PSEAE\|EnsemblGenome=PA1638\|UniProtKB=Q9I387	Pseudomonas aeruginosa	LDO
YERPE\|EnsemblGenome=YP_1682\|UniProtKB=Q9ZC49	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAE76264\|UniProtKB=P77454	Escherichia coli	O
SALTY\|EnsemblGenome=STM1525\|UniProtKB=Q8ZPI2	Salmonella typhimurium	LDO
YERPE\|EnsemblGenome=YP_3492\|UniProtKB=Q8ZHF1	Yersinia pestis	LDO
ECOLI\|EnsemblGenome=BAA15206\|UniProtKB=P0A6W0	Escherichia coli	LDO