PANTHER Gene Information

Gene Symbol(s):

TNFAIP6

Organism:

Canis lupus familiaris

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Gene Name:

TNF alpha induced protein 6

Gene ID:

ENSCAFG00845008460.1

Protein ID:

A0A8I3N7F9

Persistent Id:

PTN009204346

Alternate Ids:

A0A8I3N7F9(Synonym)	ENSCAFT00845014876(Ensembl_TRS)
ENSCAFP00845011530(Ensembl_PRO)	ENSCAFG00845008460(Ensembl)
A0A8I3N7F9_CANLF(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	CUBILIN-LIKE PROTEIN (PTHR46908)
PANTHER Subfamily:	TUMOR NECROSIS FACTOR-INDUCIBLE GENE 6 PROTEIN (PTHR46908:SF4)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	calcium ion binding, fibronectin binding, carboxylesterase activity, hyaluronic acid binding
GO BP Complete:	negative regulation of BMP signaling pathway, negative regulation of inflammatory response, negative regulation of osteoclast differentiation, negative regulation of neutrophil chemotaxis, cell adhesion, ovarian cumulus expansion, hyaluronan metabolic process, positive regulation of receptor clustering, fibronectin fibril organization, negative regulation of osteoblast differentiation
GO CC Complete:	extracellular space

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Innate Immune System, Immune System, Neutrophil degranulation

Orthologs

ID	Organism	Type
HUMAN\|HGNC=11898\|UniProtKB=P98066	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000012533.5\|UniProtKB=K7A7P4	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000022498.2\|UniProtKB=G3S056	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000010927.4\|UniProtKB=F7GLN3	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1195266\|UniProtKB=O08859	Mus musculus	LDO
RAT\|RGD=621359\|UniProtKB=B0BN34	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000007239.4\|UniProtKB=Q5W1C4	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000023716.4\|UniProtKB=I3L7U2	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000012104.4\|UniProtKB=A0A5F5PRN5	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000027956.4\|UniProtKB=M3XAE8	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000003606.3\|UniProtKB=F7C6K7	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000006974.2\|UniProtKB=F7D8H4	Ornithorhynchus anatinus	O
ORNAN\|Ensembl=ENSOANG00000037517.1\|UniProtKB=A0A6I8NT24	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010009793.1\|UniProtKB=A0A8V0YC45	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000003674.4\|UniProtKB=H9G7X4	Anolis carolinensis	LDO
XENLA\|Gene=tnfaip6.S\|UniProtKB=A0A1L8EP24	Xenopus laevis	O
XENLA\|Gene=tnfaip6.L\|UniProtKB=Q5I051	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-988687\|UniProtKB=F7EDU7	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000018870.2\|UniProtKB=H2MXA1	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-060421-2654\|UniProtKB=B0UY56	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000011184.1\|UniProtKB=W5MZD2	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000002695.1\|UniProtKB=W5M458	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118408593\|UniProtKB=A0A9J7HVE9	Branchiostoma floridae	LDO
BRAFL\|Gene=LOC118410465\|UniProtKB=A0A9J7MII1	Branchiostoma floridae	O
BRAFL\|Gene=LOC118432589\|UniProtKB=A0A9J7NDQ4	Branchiostoma floridae	O
BRAFL\|Gene=LOC118410577\|UniProtKB=A0A9J7KQC8	Branchiostoma floridae	O
BRAFL\|Gene=LOC118410646\|UniProtKB=A0A9J7MI93	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC115920030\|UniProtKB=A0A7M7N3W1	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC577429\|UniProtKB=A0A7M7NKZ3	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC578458\|UniProtKB=A0A7M7HN29	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC580195\|UniProtKB=A0A7M7P390	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100893543\|UniProtKB=A0A7M7PMP3	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100892181\|UniProtKB=A0A7M7GIU7	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100891600\|UniProtKB=A0A7M7PAC5	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100889195\|UniProtKB=A0A7M7P8S4	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115929944\|UniProtKB=A0A7M7PVQ2	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00013855\|UniProtKB=Q20911	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG08530\|UniProtKB=A8X768	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00095917\|UniProtKB=A0A2A6BRH5	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0259140\|UniProtKB=Q9VTP0	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP005526\|UniProtKB=A0A1S4GQ51	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC013670\|UniProtKB=D6WKF5	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_245200\|UniProtKB=E9GMS7	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_227615\|UniProtKB=E9H7T2	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_110979\|UniProtKB=E9H7S5	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_326443\|UniProtKB=E9H7S2	Daphnia pulex	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_240712\|UniProtKB=E9GCB5	Daphnia pulex	O
HELRO\|EnsemblGenome=HelroG190380\|UniProtKB=T1FRY0	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g238138\|UniProtKB=A7RGS9	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g157862\|UniProtKB=A7RFB6	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g201700\|UniProtKB=A7RT04	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g23900\|UniProtKB=A7RZS7	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g198354\|UniProtKB=A7RKA8	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG62701\|UniProtKB=B3SEL3	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG53274\|UniProtKB=B3RNS9	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG61598\|UniProtKB=B3SBF6	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG53272\|UniProtKB=B3RNS7	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG61597\|UniProtKB=B3SBF5	Trichoplax adhaerens	O