PANTHER Gene Information

Gene Symbol(s):

MFSD12

Organism:

Canis lupus familiaris

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Tree

Gene Name:

Major facilitator superfamily domain containing 12

Gene ID:

ENSCAFG00845009196.1

Protein ID:

A0A8I3RV40

Persistent Id:

PTN008965399

Alternate Ids:

A0A8I3RV40(Synonym)	ENSCAFG00845009196(Ensembl)
A0A8I3RV40_CANLF(UniProtKB-ID)	ENSCAFP00845012672(Ensembl_PRO)
ENSCAFT00845016291(Ensembl_TRS)
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PANTHER Classification

PANTHER Family:	MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN (PTHR11328)
PANTHER Subfamily:	MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 12 (PTHR11328:SF28)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	organic substance transport
PANTHER GO-slim Cellular Component:	plasma membrane
PANTHER protein class:	primary active transporter

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	symporter activity, cysteine transmembrane transporter activity
GO BP Complete:	negative regulation of melanin biosynthetic process, regulation of melanin biosynthetic process, carbohydrate transport, pigment metabolic process involved in pigmentation, cysteine transmembrane transport
GO CC Complete:	melanosome, membrane, late endosome, plasma membrane, lysosome

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=28299\|UniProtKB=Q6NUT3	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000010267.6\|UniProtKB=K7CE45	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000002205.3\|UniProtKB=G3QIG5	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000010653.4\|UniProtKB=H9Z584	Macaca mulatta	LDO
MOUSE\|MGI=MGI=3604804\|UniProtKB=Q3U481	Mus musculus	LDO
RAT\|RGD=1307722\|UniProtKB=F1M4E3	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000014979.6\|UniProtKB=F1MZJ3	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000026169.4\|UniProtKB=F1S7R4	Sus scrofa	LDO
FELCA\|Ensembl=ENSFCAG00000000883.6\|UniProtKB=A0A5F5XEP1	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000006897.4\|UniProtKB=A0A5F8GS74	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000014325.4\|UniProtKB=A0A6I8P2P4	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010028127.1\|UniProtKB=A0A8V1A7I3	Gallus gallus	LDO
XENLA\|Gene=mfsd12.L\|UniProtKB=Q6NUB9	Xenopus laevis	O
XENLA\|Gene=LOC108706796\|UniProtKB=A0A8J0U8Q7	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-995523\|UniProtKB=Q5M7K1	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000007898.2\|UniProtKB=H2LUY0	Oryzias latipes	LDO
DANRE\|Gene=mfsd12b\|UniProtKB=A0A8M9PZC8	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-030131-4642\|UniProtKB=F1R9L4	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000001259.1\|UniProtKB=W5LZ76	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000024618.1\|UniProtKB=H2XPZ1	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118410167\|UniProtKB=A0A9J7MHF6	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC105445269\|UniProtKB=A0A7M7N9M9	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00017530\|UniProtKB=Q19498	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00034984\|UniProtKB=A8XK38	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00113034\|UniProtKB=A0A454XQC6	Pristionchus pacificus	LDO
ANOGA\|EnsemblGenome=AGAP011492\|UniProtKB=A0A1S4H7V6	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC013631\|UniProtKB=D6W6W0	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC004584\|UniProtKB=D6W847	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_319148\|UniProtKB=E9GKU5	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_304667\|UniProtKB=E9FVJ5	Daphnia pulex	LDO
HELRO\|EnsemblGenome=HelroG110029\|UniProtKB=T1EEY4	helobdella robusta	LDO
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g110254\|UniProtKB=A7S9Q9	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g80101\|UniProtKB=A7RFU4	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g125342\|UniProtKB=A7SNU2	Nematostella vectensis	LDO
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g95008\|UniProtKB=A7RVS2	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g196568\|UniProtKB=A7RFU3	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g102846\|UniProtKB=A7S3B7	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g105998\|UniProtKB=A7S679	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g83720\|UniProtKB=A7RJX5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g80169\|UniProtKB=A7RFU2	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g246446\|UniProtKB=A7SNT9	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG30948\|UniProtKB=B3S7Z3	Trichoplax adhaerens	LDO
PARTE\|EnsemblGenome=GSPATT00033069001\|UniProtKB=A0BXE9	Paramecium tetraurelia	LDO
PHYRM\|Gene=H3GER6_PHYRM\|UniProtKB=H3GER6	Phytophthora ramorum	LDO
AMBTC\|EnsemblGenome=AMTR_s00133p00099940\|UniProtKB=W1P9S4	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_46G00680\|UniProtKB=A0A0K9P2A9	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma07_g01780\|UniProtKB=A0A804JR39	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_035602mg\|UniProtKB=K4A9P6	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3001G492100\|UniProtKB=C5WWU2	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb402450\|UniProtKB=A0A804RAK7	Zea mays	O
ORYSJ\|EnsemblGenome=Os03g0168000\|UniProtKB=Q8S7U2	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_1g73850v3\|UniProtKB=I1H9B0	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.4HG0403130\|UniProtKB=A0A8I7B7L5	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS4B02G283600\|UniProtKB=A0A3B6IWQ6	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4A02G020100\|UniProtKB=A0A3B6HMF5	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4D02G282300\|UniProtKB=A0A3B6JMV9	Triticum aestivum	O
SETIT\|EnsemblGenome=SETIT_029800mg\|UniProtKB=K3ZT70	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3002G352800\|UniProtKB=A0A1B6QF55	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb325500\|UniProtKB=A0A804QDC7	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os07g0578200\|UniProtKB=Q0D566	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_1g23580v3\|UniProtKB=I1GT18	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.2HG0131470\|UniProtKB=A0A8I6X5Q1	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS2A02G187600\|UniProtKB=A0A3B6AWD6	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2B02G219700\|UniProtKB=A0A3B6C3I3	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2D02G200300\|UniProtKB=W5C3X8	Triticum aestivum	LDO
NELNU\|Gene=LOC104597626\|UniProtKB=A0A1U7ZV90	Nelumbo nucifera	O
NELNU\|Gene_ORFName=HUJ06_031568\|UniProtKB=A0A1U7YVR2	Nelumbo nucifera	O
NELNU\|Gene_ORFName=HUJ06_031569\|UniProtKB=A0A1U7YT17	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110775374\|UniProtKB=A0A9R0JI20	Spinacia oleracea	LDO
SPIOL\|Gene=LOC110780980\|UniProtKB=A0A9R0I1I5	Spinacia oleracea	O
HELAN\|EnsemblGenome=HanXRQr2_Chr04g0180461\|UniProtKB=A0A251V1K6	Helianthus annuus	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a025947mg\|UniProtKB=A0A022QKZ7	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_25045\|UniProtKB=A0A2G2YK20	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400023279\|UniProtKB=M1C4U1	Solanum tuberosum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400007701\|UniProtKB=M1ACR6	Solanum tuberosum	O
CAPAN\|EnsemblGenome=T459_03032\|UniProtKB=A0A2G3ALR5	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400028978\|UniProtKB=M1CTV3	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc01g073670.3\|UniProtKB=A0A3Q7EGK4	Solanum lycopersicum	O
CAPAN\|EnsemblGenome=T459_03033\|UniProtKB=A0A2G3ALN8	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400031131\|UniProtKB=M1D2R4	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc01g073660.3\|UniProtKB=A0A3Q7EH21	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107781247\|UniProtKB=A0A1S3YZ62	Nicotiana tabacum	LDO
TOBAC\|Gene=LOC107774742\|UniProtKB=A0A1S3YCZ1	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi13g01840\|UniProtKB=D7TNT2	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_E04336\|UniProtKB=A0A059CCD1	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=GSBRNA2T00022035001\|UniProtKB=A0A078GDF6	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_A04P33250.1\|UniProtKB=A0A078H0W4	Brassica napus	O
BRACM\|EnsemblGenome=Bra037659\|UniProtKB=M4F996	Brassica campestris	O
BRANA\|Gene_ORFName=DARMORV10_C04P05190.1\|UniProtKB=A0A078FTK0	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_A05P04480.1\|UniProtKB=A0A078JA81	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra004823\|UniProtKB=M4CKT7	Brassica campestris	LDO
ARATH\|TAIR=locus=2050626\|UniProtKB=Q8L7S2	Arabidopsis thaliana	LDO
BRANA\|Gene_ORFName=DARMORV10_C04P32650.1\|UniProtKB=A0A078HW22	Brassica napus	O
BRACM\|EnsemblGenome=Bra014515\|UniProtKB=M4DDE7	Brassica campestris	O
ARATH\|TAIR=locus=2101442\|UniProtKB=Q8L7Z7	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107918374\|UniProtKB=A0A1U8KRT7	Gossypium hirsutum	O
GOSHI\|Gene=LOC107926338\|UniProtKB=A0A1U8LDI0	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_036520\|UniProtKB=A0A061FJ54	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g011925mg\|UniProtKB=A0A067E543	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_001G231500v3\|UniProtKB=A0A2K2C2C3	Populus trichocarpa	LDO
POPTR\|EnsemblGenome=POPTR_009G024600v3\|UniProtKB=A0A2K1Z1L9	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_001G232100v3\|UniProtKB=U5GR42	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_10G153000\|UniProtKB=A0A251K1Q2	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1776390\|UniProtKB=B9REN1	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_08G158600\|UniProtKB=I1KTR2	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_15G267700\|UniProtKB=K7ME40	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_2g062270\|UniProtKB=A2Q3C2	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr14_00100\|UniProtKB=A0A2I4FRR6	Juglans regia	LDO
JUGRE\|EnsemblGenome=Jr14_00120\|UniProtKB=A0A6P9DZ93	Juglans regia	LDO
JUGRE\|EnsemblGenome=Jr14_00110\|UniProtKB=A0A6P9E163	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_7G430150\|UniProtKB=A0A0A0K652	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_2G001700\|UniProtKB=A0A251QBZ7	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_230598\|UniProtKB=D8R0Y5	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_33300\|UniProtKB=D8S153	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c17_11410\|UniProtKB=A0A2K1J3H1	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0020s0019\|UniProtKB=A0A2R6XE16	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_002160050\|UniProtKB=A0A1Y1I244	Klebsormidium nitens	LDO
CHLAA\|EnsemblGenome=Caur_2083\|UniProtKB=A9WEY0	Chloroflexus aurantiacus	O
CHLAA\|EnsemblGenome=Caur_1783\|UniProtKB=A9WD33	Chloroflexus aurantiacus	O
BACSU\|EnsemblGenome=BSU_06160\|UniProtKB=O34368	Bacillus subtilis	O
BACSU\|EnsemblGenome=BSU_17570\|UniProtKB=P94488	Bacillus subtilis	O
BACSU\|EnsemblGenome=BSU_12310\|UniProtKB=O34961	Bacillus subtilis	O
GLOVI\|Gene=Q7NEC1_GLOVI\|UniProtKB=Q7NEC1	Gloeobacter violaceus	O
GLOVI\|Gene=Q7NDI5_GLOVI\|UniProtKB=Q7NDI5	Gloeobacter violaceus	O
SYNY3\|EnsemblGenome=BAA18257\|UniProtKB=P74168	Synechocystis	O
FUSNN\|EnsemblGenome=FN0222\|UniProtKB=Q8RGR4	Fusobacterium nucleatum	O
XANCP\|EnsemblGenome=XCC4121\|UniProtKB=Q8P3F0	Xanthomonas campestris	O
XANCP\|EnsemblGenome=XCC4078\|UniProtKB=Q8P3J3	Xanthomonas campestris	O
SALTY\|EnsemblGenome=STM4017\|UniProtKB=Q9L7R4	Salmonella typhimurium	O
YERPE\|Gene_OrderedLocusName=YPO0995\|UniProtKB=A0A7Y8RHN7	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAE77433\|UniProtKB=P32136	Escherichia coli	O
SALTY\|EnsemblGenome=STM4299\|UniProtKB=P30878	Salmonella typhimurium	O
ECOLI\|EnsemblGenome=BAE78122\|UniProtKB=P02921	Escherichia coli	O
SALTY\|EnsemblGenome=STM4018\|UniProtKB=Q9L7R5	Salmonella typhimurium	O
ECOLI\|EnsemblGenome=BAA15367\|UniProtKB=P0CE44	Escherichia coli	O
ECOLI\|EnsemblGenome=BAE77432\|UniProtKB=P32137	Escherichia coli	O
SALTY\|EnsemblGenome=STM0149\|UniProtKB=H9L454	Salmonella typhimurium	O
SALTY\|EnsemblGenome=STM0042\|UniProtKB=Q8ZRZ1	Salmonella typhimurium	O
SALTY\|EnsemblGenome=STM4065\|UniProtKB=Q8ZKR3	Salmonella typhimurium	O
SALTY\|EnsemblGenome=STM3750\|UniProtKB=Q7CPH1	Salmonella typhimurium	O
YERPE\|Gene_OrderedLocusName=YPO1226\|UniProtKB=Q0WHI1	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAE76054\|UniProtKB=P75683	Escherichia coli	O
ECOLI\|EnsemblGenome=BAE77636\|UniProtKB=P31435	Escherichia coli	O