PANTHER Gene Information

Gene Symbol(s):

DDX41

Organism:

Canis lupus familiaris

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Gene Name:

RNA helicase

Gene ID:

ENSCAFG00845009380.1

Protein ID:

A0A8I3NC92

Persistent Id:

PTN002776125

Alternate Ids:

XM_536417(refSeq)	ENSCAFT00845016565(Ensembl_TRS)
A0A8I3NC92_CANLF(UniProtKB-ID)	73953218(GI)
A0A8I3NC92(Synonym)	ENSCAFG00845009380(Ensembl)
ENSCAFP00845012886(Ensembl_PRO)	479274(GeneID)
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PANTHER Classification

PANTHER Family:	ATP-DEPENDENT RNA HELICASE DBP3 (PTHR47958)
PANTHER Subfamily:	ATP-DEPENDENT RNA HELICASE DDX41-RELATED (PTHR47958:SF103)
PANTHER GO-slim Molecular Function:	helicase activity mRNA binding catalytic activity, acting on RNA
PANTHER GO-slim Biological Process:	mRNA splicing, via spliceosome
PANTHER GO-slim Cellular Component:	spliceosomal complex
PANTHER protein class:	RNA helicase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	ATP binding, RNA binding, RNA helicase activity, mRNA binding, hydrolase activity
GO BP Complete:	mRNA splicing, via spliceosome
GO CC Complete:	spliceosomal complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Innate Immune System, Cytosolic sensors of pathogen-associated DNA , Processing of Capped Intron-Containing Pre-mRNA, Immune System, mRNA Splicing, Metabolism of RNA, Regulation of innate immune responses to cytosolic DNA, STING mediated induction of host immune responses, mRNA Splicing - Major Pathway

Orthologs

ID	Organism	Type
HUMAN\|HGNC=18674\|UniProtKB=Q9UJV9	Homo sapiens	LDO
GORGO\|Ensembl=ENSGGOG00000014484.3\|UniProtKB=G3REY5	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000016911.4\|UniProtKB=F7G4G3	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1920185\|UniProtKB=Q91VN6	Mus musculus	LDO
RAT\|RGD=40990865\|UniProtKB=A0A8I5ZL40	Rattus norvegicus	O
RAT\|RGD=6486301\|UniProtKB=A0A8I5ZMZ5	Rattus norvegicus	O
RAT\|RGD=1311758\|UniProtKB=B2RYL8	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000015187.5\|UniProtKB=A3KN07	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000032642.3\|UniProtKB=A0A287AWY6	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000009688.4\|UniProtKB=F7B876	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000001542.5\|UniProtKB=M3VWU8	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000004714.3\|UniProtKB=F6QGJ3	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000009671.3\|UniProtKB=A0A6I8NQ89	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010009447.1\|UniProtKB=A0A8V0Y242	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000005778.4\|UniProtKB=G1KES9	Anolis carolinensis	LDO
XENLA\|Gene=ddx41.L\|UniProtKB=A0A1L8GXY5	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-967537\|UniProtKB=F6VY98	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000006688.2\|UniProtKB=H2LQQ1	Oryzias latipes	LDO
DANRE\|Gene=LOC108179221\|UniProtKB=A0A4P2L339	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000011956.1\|UniProtKB=W5N245	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000008215.4\|UniProtKB=Q1RPW7	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118413731\|UniProtKB=A0A9J7KZM9	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC591793\|UniProtKB=A0A7M7REP9	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00019245\|UniProtKB=Q9N5K1	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00033648\|UniProtKB=A8XGH2	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00100403\|UniProtKB=A0A2A6BN97	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0015331\|UniProtKB=Q9V3C0	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP004711\|UniProtKB=Q7PMT8	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC016289\|UniProtKB=D6X2V8	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_190268\|UniProtKB=E9FR98	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW016533\|UniProtKB=B7P3Q1	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG78123\|UniProtKB=T1G384	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g158506\|UniProtKB=A7RGX3	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG51106\|UniProtKB=B3SBY3	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_10818\|UniProtKB=A9V7B8	Monosiga brevicollis	LDO
CRYNJ\|EnsemblGenome=CNG01650\|UniProtKB=Q5KE58	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_04587\|UniProtKB=A0A0D1DT51	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_17019\|UniProtKB=E3L490	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_91848\|UniProtKB=F4PBP5	Batrachochytrium dendrobatidis	LDO
DICDI\|dictyBase=DDB_G0287361\|UniProtKB=Q54KG1	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_28243\|UniProtKB=F0ZBI8	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_11_0190\|UniProtKB=Q4QH61	Leishmania major	LDO
PLAF7\|Gene_ORFName=PF3D7_0527900\|UniProtKB=A0A5K1K8X8	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00037537001\|UniProtKB=A0CE84	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00034714001\|UniProtKB=A0C369	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_269450\|UniProtKB=B8C8J5	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GH04_PHYRM\|UniProtKB=H3GH04	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_07g334200v5\|UniProtKB=A0A2K3DK31	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00062p00113470\|UniProtKB=U5DAR0	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_45G00120\|UniProtKB=A0A0K9P0G5	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma01_g07330\|UniProtKB=A0A804HRA6	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma02_g11060\|UniProtKB=A0A804I1H8	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_016661mg\|UniProtKB=K3YQW7	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3001G376800\|UniProtKB=C5X0P4	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb394960\|UniProtKB=C4J233	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os06g0697200\|UniProtKB=Q5Z6G5	Oryza sativa	O
ORYSJ\|Gene_OrderedLocusName=LOC_Os02g05660\|UniProtKB=Q0E3X4	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_3g03990v3\|UniProtKB=I1HX96	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0465860\|UniProtKB=A0A8I6XQY0	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS5A02G153700\|UniProtKB=A0A3B6KGF3	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5D02G159000\|UniProtKB=A0A3B6MNA8	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5B02G152200\|UniProtKB=A0A3B6LK07	Triticum aestivum	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.3HG0240040\|UniProtKB=A0A8I6XKP3	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS3B02G141300\|UniProtKB=A0A3B6FLL2	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3A02G122100\|UniProtKB=A0A3B6EEB5	Triticum aestivum	LDO
NELNU\|Gene_ORFName=HUJ06_028737\|UniProtKB=A0A1U7ZC92	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110782504\|UniProtKB=A0A9R0I4F0	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr02g0048361\|UniProtKB=A0A251VDU8	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C100013770\|UniProtKB=A0A9R1WGU0	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a003346mg\|UniProtKB=A0A022PZU2	Erythranthe guttata	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400014141\|UniProtKB=M1B405	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc03g117440.3\|UniProtKB=A0A3Q7FTZ2	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107824327\|UniProtKB=A0A1S4CZY7	Nicotiana tabacum	LDO
CAPAN\|EnsemblGenome=T459_17525\|UniProtKB=A0A1U8HBG5	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400028504\|UniProtKB=M1CRV4	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc06g068280.3\|UniProtKB=A0A3Q7GZX5	Solanum lycopersicum	O
TOBAC\|Gene=LOC107778704\|UniProtKB=A0A1S3YQJ0	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi09g00722\|UniProtKB=A5B7F0	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_C00570\|UniProtKB=A0A059CL68	Eucalyptus grandis	O
EUCGR\|EnsemblGenome=EUGRSUZ_J03085\|UniProtKB=A0A059AJ43	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=GSBRNA2T00068859001\|UniProtKB=A0A078HT98	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00033630001\|UniProtKB=A0A078J7W6	Brassica napus	O
BRACM\|EnsemblGenome=Bra003568\|UniProtKB=M4CH85	Brassica campestris	O
BRACM\|EnsemblGenome=Bra035177\|UniProtKB=M4F280	Brassica campestris	O
BRACM\|EnsemblGenome=Bra018133\|UniProtKB=M4DNP6	Brassica campestris	O
BRANA\|Gene_ORFName=GSBRNA2T00066397001\|UniProtKB=A0A078HM41	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra008471\|UniProtKB=M4CW74	Brassica campestris	LDO
ARATH\|TAIR=locus=2119176\|UniProtKB=Q9SZB4	Arabidopsis thaliana	O
ARATH\|TAIR=locus=2176192\|UniProtKB=Q9LU46	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107906446\|UniProtKB=A0A1U8JFA6	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_044716\|UniProtKB=A0A061FR73	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g0393781mg\|UniProtKB=A0A067EUH0	Citrus sinensis	O
CITSI\|Gene_ORFName=CISIN_1g007831mg\|UniProtKB=A0A067E841	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_004G224000v3\|UniProtKB=B9N0D8	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_04G109200\|UniProtKB=A0A2C9W3M8	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1620570\|UniProtKB=B9RED5	Ricinus communis	O
RICCO\|Gene_ORFName=RCOM_0902150\|UniProtKB=B9RVC6	Ricinus communis	O
RICCO\|Gene_ORFName=RCOM_0395640\|UniProtKB=B9SS37	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_03G236700\|UniProtKB=I1JRB6	Glycine max	LDO
SOYBN\|EnsemblGenome=GLYMA_19G082800\|UniProtKB=K7MX92	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_1g026830\|UniProtKB=A0A072VES2	Medicago truncatula	O
MEDTR\|EnsemblGenome=MTR_1g095810\|UniProtKB=G7I9M7	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr12_20210\|UniProtKB=A0A2I4HT53	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_7G432260\|UniProtKB=A0A0A0K6A2	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_3G092400\|UniProtKB=M5WR00	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_230807\|UniProtKB=D8R604	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_236355\|UniProtKB=D8T7U5	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_116186\|UniProtKB=D8SG73	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_132834\|UniProtKB=D8T656	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c25_520\|UniProtKB=A9TEN1	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0164s0014\|UniProtKB=A0A2R6W3I9	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_003440100\|UniProtKB=A0A1Y1ICZ2	Klebsormidium nitens	LDO
NITMS\|EnsemblGenome=Nmar_1182\|UniProtKB=A9A5S3	Nitrosopumilus maritimus	O
SACS2\|EnsemblGenome=SSO2036\|UniProtKB=Q97WT0	Sulfolobus solfataricus	O
SACS2\|EnsemblGenome=SSO1889\|UniProtKB=Q97X64	Sulfolobus solfataricus	O