PANTHER Gene Information

Gene Symbol(s):

SYT8

Organism:

Canis lupus familiaris

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Gene Name:

Synaptotagmin 8

Gene ID:

ENSCAFG00845010168.1

Protein ID:

A0A8I3N970

Persistent Id:

PTN000001842

Alternate Ids:

A0A8I3N970(Synonym)	ENSCAFG00845010168(Ensembl)
A0A8I3N970_CANLF(UniProtKB-ID)	ENSCAFT00845017879(Ensembl_TRS)
ENSCAFP00845013925(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	SYNAPTOTAGMIN (PTHR10024)
PANTHER Subfamily:	SYNAPTOTAGMIN-8 (PTHR10024:SF249)
PANTHER GO-slim Molecular Function:	SNARE binding calcium ion binding phosphatidylserine binding clathrin binding
PANTHER GO-slim Biological Process:	synaptic vesicle exocytosis synaptic vesicle endocytosis calcium-ion regulated exocytosis
PANTHER GO-slim Cellular Component:	axon plasma membrane synaptic vesicle membrane secretory granule
PANTHER protein class:	membrane trafficking regulatory protein

Pathway Categories:

Synaptic vesicle trafficking

Synaptotagmin

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	calcium ion sensor activity, calcium-dependent protein binding, SNARE binding, calcium-dependent phospholipid binding
GO BP Complete:	vesicle-mediated transport, acrosome reaction, calcium-dependent activation of synaptic vesicle fusion, regulation of synaptic vesicle exocytosis, regulation of calcium ion-dependent exocytosis
GO CC Complete:	exocytic vesicle, cytoplasm, membrane, vesicle, synaptic vesicle membrane, dense core granule, plasma membrane, axon

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Membrane Trafficking, Clathrin-mediated endocytosis, Cargo recognition for clathrin-mediated endocytosis, Vesicle-mediated transport

Orthologs

ID	Organism	Type
HUMAN\|HGNC=19264\|UniProtKB=Q8NBV8	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000003160.7\|UniProtKB=H2R5N4	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000008429.3\|UniProtKB=G3QZC5	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000004837.4\|UniProtKB=F7AUE6	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1859867\|UniProtKB=Q9R0N6	Mus musculus	LDO
RAT\|RGD=68399\|UniProtKB=Q925B4	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000040103.3\|UniProtKB=F1MRS2	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000023537.4\|UniProtKB=I3LBJ6	Sus scrofa	LDO
FELCA\|Ensembl=ENSFCAG00000025962.4\|UniProtKB=M3X6S3	Felis catus	LDO
CHICK\|Ensembl=ENSGALG00010024615.1\|UniProtKB=A0A8V1A2U0	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000009464.4\|UniProtKB=G1KIZ9	Anolis carolinensis	LDO
XENLA\|Gene=syt1.L\|UniProtKB=Q66KE5	Xenopus laevis	O
XENLA\|Gene=LOC108715204\|UniProtKB=A0A1L8GD54	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-978920\|UniProtKB=F6YG36	Xenopus tropicalis	LDO
DANRE\|Gene=LOC103909874\|UniProtKB=A0A8M9PND4	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000002263.1\|UniProtKB=W5M2P4	lepisosteus oculatus	LDO
BRAFL\|Gene_ORFName=BRAFLDRAFT_120531\|UniProtKB=C3Z4L9	Branchiostoma floridae	O
BRAFL\|Gene=LOC118417681\|UniProtKB=A0A9J7LAS0	Branchiostoma floridae	O
BRAFL\|Gene=LOC118406658\|UniProtKB=A0A9J7KK38	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC752447\|UniProtKB=A0A7M7NZL4	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC755798\|UniProtKB=A0A7M7G0T7	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115917880\|UniProtKB=A0A7M7NYG5	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115921646\|UniProtKB=A0A7M7NGD2	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC373478\|UniProtKB=A0A7M7NYD5	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00004925\|UniProtKB=O16700	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00028699\|UniProtKB=A8X269	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00118488\|UniProtKB=A0A2A6C9X4	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00004922\|UniProtKB=K8FE10	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00035598\|UniProtKB=A8XLH0	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00090226\|UniProtKB=A0A2A6BQW9	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00008438\|UniProtKB=G5EDP5	Caenorhabditis elegans	O
PRIPA\|EnsemblGenome=WBGene00091526\|UniProtKB=A0A2A6CXX6	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00004923\|UniProtKB=Q965S5	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00028703\|UniProtKB=A8X273	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00118741\|UniProtKB=A0A2A6CGF4	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00004921\|UniProtKB=P34693	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00032329\|UniProtKB=A8XCL2	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00097802\|UniProtKB=A0A2A6BZB9	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0261089\|UniProtKB=C0HDP4	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP008650\|UniProtKB=A0A1S4GYU8	Anopheles gambiae	O
DROME\|FlyBase=FBgn0004242\|UniProtKB=P21521	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP007942\|UniProtKB=Q7PN22	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC007227\|UniProtKB=D2A0P6	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_442623\|UniProtKB=E9FTC0	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW011463\|UniProtKB=B7Q6I0	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG170390\|UniProtKB=T1F2Z9	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG65797\|UniProtKB=T1FYC7	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG163371\|UniProtKB=T1ETY8	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG78642\|UniProtKB=T1G3E0	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG82086\|UniProtKB=T1G4M6	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG85838\|UniProtKB=T1G633	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g247877\|UniProtKB=A7SX18	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g85661\|UniProtKB=A7RKX9	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g136167\|UniProtKB=A7SX19	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g115870\|UniProtKB=A7SEZ4	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g136571\|UniProtKB=A7SXC9	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g130783\|UniProtKB=A7ST77	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g136185\|UniProtKB=A7SX17	Nematostella vectensis	O
TRIAD\|Gene_ORFName=TRIADDRAFT_61791\|UniProtKB=B3SBZ4	Trichoplax adhaerens	O