PANTHER Gene Information

Gene Symbol(s):

GNE

Organism:

Canis lupus familiaris

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Gene Name:

Glucosamine (UDP-N-acetyl)-2-epimerase_N-acetylmannosamine kinase

Gene ID:

ENSCAFG00845011465.1

Protein ID:

A0A8I3NFK8

Persistent Id:

PTN001451146

Alternate Ids:

ENSCAFT00845020446(Ensembl_TRS)	A0A8I3NFK8(Synonym)
ENSCAFP00845016027(Ensembl_PRO)	ENSCAFG00845011465(Ensembl)
A0A8I3NFK8_CANLF(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	ROK (REPRESSOR, ORF, KINASE) FAMILY (PTHR18964)
PANTHER Subfamily:	BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE_N-ACETYLMANNOSAMINE KINASE (PTHR18964:SF149)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	winged helix/forkhead transcription factor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	N-acylmannosamine kinase activity, UDP-N-acetylglucosamine 2-epimerase activity, hydrolase activity, hydrolyzing O-glycosyl compounds
GO BP Complete:	UDP-N-acetylglucosamine metabolic process, carbohydrate phosphorylation
GO CC Complete:	-

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Metabolism of proteins, Post-translational protein modification, Asparagine N-linked glycosylation, Synthesis of substrates in N-glycan biosythesis, Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein, Sialic acid metabolism

Orthologs

ID	Organism	Type
HUMAN\|HGNC=23657\|UniProtKB=Q9Y223	Homo sapiens	LDO
GORGO\|Ensembl=ENSGGOG00000013160.3\|UniProtKB=A0A2I2ZRR3	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000006135.4\|UniProtKB=G7NFA8	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1354951\|UniProtKB=Q91WG8	Mus musculus	LDO
RAT\|RGD=69239\|UniProtKB=O35826	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000001142.5\|UniProtKB=F1MIL9	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000037468.3\|UniProtKB=A0A287BMG4	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000014124.4\|UniProtKB=A0A5F5PZU5	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000012765.5\|UniProtKB=A0A337SBY2	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000002632.4\|UniProtKB=F7FUA5	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000011137.3\|UniProtKB=A0A6I8P074	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010013225.1\|UniProtKB=A0A8V0YL47	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000001857.4\|UniProtKB=H9G5T0	Anolis carolinensis	LDO
XENLA\|Gene=gne.L\|UniProtKB=A0A1L8HXN5	Xenopus laevis	O
XENLA\|Gene=gne.S\|UniProtKB=A0A8J0U5P1	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-1003644\|UniProtKB=A0A6I8RBY7	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000020818.2\|UniProtKB=A0A3B3IHX6	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040426-1848\|UniProtKB=Q6P3K2	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000011146.1\|UniProtKB=W5MZ88	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118416361\|UniProtKB=A0A9J7MSL4	Branchiostoma floridae	O
BRAFL\|Gene=LOC118413467\|UniProtKB=A0A9J7KYB5	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC590539\|UniProtKB=A0A7M7NWF5	Strongylocentrotus purpuratus	LDO
PHYRM\|Gene=H3HBQ5_PHYRM\|UniProtKB=H3HBQ5	Phytophthora ramorum	LDO
NITMS\|EnsemblGenome=Nmar_1576\|UniProtKB=A9A5Z4	Nitrosopumilus maritimus	LDO
PYRAE\|EnsemblGenome=PAE3437\|UniProtKB=Q8ZT49	Pyrobaculum aerophilum	LDO
HALSA\|EnsemblGenome=VNG_2629G\|UniProtKB=Q9HMA7	Halobacterium salinarum	LDO
STRCO\|Gene_OrderedLocusName=SCO0063\|UniProtKB=Q9S1S9	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO7568\|UniProtKB=Q9F3A7	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO6110\|UniProtKB=Q9ADF3	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO1077\|UniProtKB=Q9K422	Streptomyces coelicolor	O
MYCTU\|Gene_OrderedLocusName=Rv0650\|UniProtKB=I6Y8D3	Mycobacterium tuberculosis	O
HAEIN\|EnsemblGenome=HI_0144\|UniProtKB=P44541	Haemophilus influenzae	O
VIBCH\|EnsemblGenome=VC_1782\|UniProtKB=Q9KR61	Vibrio cholerae	O
XANCP\|EnsemblGenome=XCC0051\|UniProtKB=Q8PED0	Xanthomonas campestris	O
XANCP\|EnsemblGenome=XCC4053\|UniProtKB=Q8P3L8	Xanthomonas campestris	O
SALTY\|EnsemblGenome=STM3336\|UniProtKB=Q8ZLQ8	Salmonella typhimurium	O
YERPE\|Gene_OrderedLocusName=YPO2036\|UniProtKB=A0A5P8YF28	Yersinia pestis	O
YERPE\|EnsemblGenome=YP_2644\|UniProtKB=Q8ZCG9	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAE77265\|UniProtKB=P45425	Escherichia coli	O
THEMA\|EnsemblGenome=TM_0808\|UniProtKB=Q9WZR5	Thermotoga maritima	O
THEMA\|EnsemblGenome=TM_0110\|UniProtKB=Q9WXW5	Thermotoga maritima	O
THEMA\|EnsemblGenome=TM_0032\|UniProtKB=Q9WXN9	Thermotoga maritima	O
THEMA\|EnsemblGenome=TM_1847\|UniProtKB=Q9X2G2	Thermotoga maritima	O
DICTD\|EnsemblGenome=Dtur_1809\|UniProtKB=B8E0R0	Dictyoglomus turgidum	O
STRR6\|EnsemblGenome=spr1519\|UniProtKB=Q8DNV3	Streptococcus pneumoniae	O
STAA8\|EnsemblGenome=SAOUHSC_00296\|UniProtKB=Q2G159	Staphylococcus aureus	O
LISMO\|EnsemblGenome=CAD00977\|UniProtKB=Q8Y3R9	Listeria monocytogenes	O
LISMO\|Gene=Q8Y3N9_LISMO\|UniProtKB=Q8Y3N9	Listeria monocytogenes	O
BACCR\|EnsemblGenome=BC_0441\|UniProtKB=Q81IE7	Bacillus cereus	O
FUSNN\|EnsemblGenome=FN1474\|UniProtKB=Q8RDN7	Fusobacterium nucleatum	O
SALTY\|EnsemblGenome=STM3681\|UniProtKB=Q8ZL71	Salmonella typhimurium	O
STRCO\|Gene_OrderedLocusName=SCO7486\|UniProtKB=Q93JB0	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO6260\|UniProtKB=Q9RKT2	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO6008\|UniProtKB=O50502	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO6115\|UniProtKB=Q9Z557	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO6566\|UniProtKB=Q8CJM5	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO2846\|UniProtKB=Q9RDA5	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO2126\|UniProtKB=P0A4E1	Streptomyces coelicolor	O
DEIRA\|EnsemblGenome=DR_2296\|UniProtKB=Q9RS31	Deinococcus radiodurans	O
BRADU\|Gene=Q89SY2_BRADU\|UniProtKB=Q89SY2	Bradyrhizobium diazoefficiens	O
CHLAA\|EnsemblGenome=Caur_2345\|UniProtKB=A9WGM2	Chloroflexus aurantiacus	O
CHLAA\|EnsemblGenome=Caur_1103\|UniProtKB=A9WJ57	Chloroflexus aurantiacus	LDO
STRCO\|Gene_OrderedLocusName=SCO1171\|UniProtKB=Q9RJZ9	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO0275\|UniProtKB=Q9S2D8	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO1261\|UniProtKB=Q9K3H9	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO1060\|UniProtKB=Q9K439	Streptomyces coelicolor	LDO
STRCO\|Gene_OrderedLocusName=SCO0794\|UniProtKB=Q9RD83	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO6600\|UniProtKB=O87855	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO0734\|UniProtKB=Q9EWT7	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO7543\|UniProtKB=Q9KYY6	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO1447\|UniProtKB=Q9L112	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO2657\|UniProtKB=Q9L1X8	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO1039\|UniProtKB=Q9K3M1	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO4285\|UniProtKB=Q9KXV6	Streptomyces coelicolor	O
MYCTU\|Gene_OrderedLocusName=Rv0485\|UniProtKB=P9WKV1	Mycobacterium tuberculosis	LDO
CLOBH\|Gene_OrderedLocusName=CBO1201\|UniProtKB=A5I138	Clostridium botulinum	O
STRR6\|EnsemblGenome=spr1950\|UniProtKB=Q8DN35	Streptococcus pneumoniae	O
LISMO\|Gene=Q8Y8W6_LISMO\|UniProtKB=Q8Y8W6	Listeria monocytogenes	O
LISMO\|Gene=Q8YAL2_LISMO\|UniProtKB=Q8YAL2	Listeria monocytogenes	O
CLOBH\|Gene_OrderedLocusName=CBO1602\|UniProtKB=A5I275	Clostridium botulinum	LDO
STRR6\|EnsemblGenome=spr0420\|UniProtKB=Q8DQZ4	Streptococcus pneumoniae	O
STRR6\|EnsemblGenome=spr0584\|UniProtKB=Q8DQN3	Streptococcus pneumoniae	LDO
STAA8\|EnsemblGenome=SAOUHSC_01646\|UniProtKB=Q2FY27	Staphylococcus aureus	LDO
LISMO\|Gene=Q8YAT1_LISMO\|UniProtKB=Q8YAT1	Listeria monocytogenes	O
LISMO\|Gene=Q8Y9K7_LISMO\|UniProtKB=Q8Y9K7	Listeria monocytogenes	O
LISMO\|Gene=Q8YAF1_LISMO\|UniProtKB=Q8YAF1	Listeria monocytogenes	O
LISMO\|Gene=Q8Y7E4_LISMO\|UniProtKB=Q8Y7E4	Listeria monocytogenes	LDO
BACSU\|EnsemblGenome=BSU_17590\|UniProtKB=P94490	Bacillus subtilis	O
BACSU\|EnsemblGenome=BSU_24850\|UniProtKB=P54495	Bacillus subtilis	LDO
BACCR\|EnsemblGenome=BC_4260\|UniProtKB=Q818J2	Bacillus cereus	LDO
THEMA\|EnsemblGenome=TM_1224\|UniProtKB=Q9X0V1	Thermotoga maritima	O
THEMA\|EnsemblGenome=TM_0393\|UniProtKB=Q9WYM4	Thermotoga maritima	O
THEMA\|EnsemblGenome=TM_0411\|UniProtKB=Q9WYP2	Thermotoga maritima	O
THEMA\|EnsemblGenome=TM_1469\|UniProtKB=Q9X1I0	Thermotoga maritima	LDO
GLOVI\|Gene=Q7NF96_GLOVI\|UniProtKB=Q7NF96	Gloeobacter violaceus	LDO
SYNY3\|Gene=xylR\|UniProtKB=Q55536	Synechocystis	LDO
LEPIN\|EnsemblGenome=LA_1437\|UniProtKB=Q8F672	Leptospira interrogans	LDO
BACTN\|EnsemblGenome=BT_2104\|UniProtKB=Q8A5Y2	Bacteroides thetaiotaomicron	O
BACTN\|EnsemblGenome=BT_3600\|UniProtKB=Q8A1Q9	Bacteroides thetaiotaomicron	O
BACTN\|EnsemblGenome=BT_0433\|UniProtKB=Q8AAN1	Bacteroides thetaiotaomicron	O
BACTN\|EnsemblGenome=BT_4654\|UniProtKB=Q89YS7	Bacteroides thetaiotaomicron	O
BACTN\|EnsemblGenome=BT_2493\|UniProtKB=Q8A4V4	Bacteroides thetaiotaomicron	LDO
RHOBA\|EnsemblGenome=RB1321\|UniProtKB=Q7UXH8	Rhodopirellula baltica	O
RHOBA\|EnsemblGenome=RB1629\|UniProtKB=Q7UX16	Rhodopirellula baltica	LDO
RHOBA\|EnsemblGenome=RB3555\|UniProtKB=Q7UU26	Rhodopirellula baltica	O
AQUAE\|EnsemblGenome=aq_1496\|UniProtKB=O67468	Aquifex aeolicus	LDO
THEYD\|EnsemblGenome=THEYE_A0100\|UniProtKB=B5YHD0	Thermodesulfovibrio yellowstonii	LDO
DICTD\|EnsemblGenome=Dtur_1684\|UniProtKB=B8E382	Dictyoglomus turgidum	O
DICTD\|EnsemblGenome=Dtur_0688\|UniProtKB=B8DZP0	Dictyoglomus turgidum	O
DICTD\|EnsemblGenome=Dtur_1680\|UniProtKB=B8E378	Dictyoglomus turgidum	O
DICTD\|EnsemblGenome=Dtur_1116\|UniProtKB=B8E2B8	Dictyoglomus turgidum	O
DICTD\|EnsemblGenome=Dtur_0887\|UniProtKB=B8E085	Dictyoglomus turgidum	LDO
FUSNN\|EnsemblGenome=FN0790\|UniProtKB=Q8RFC3	Fusobacterium nucleatum	O
FUSNN\|EnsemblGenome=FN1164\|UniProtKB=Q8REE3	Fusobacterium nucleatum	LDO
GEOSL\|EnsemblGenome=GSU1702\|UniProtKB=Q74CH1	Geobacter sulfurreducens	LDO
BRADU\|Gene=Q89X95_BRADU\|UniProtKB=Q89X95	Bradyrhizobium diazoefficiens	O
BRADU\|Gene=Q89KR3_BRADU\|UniProtKB=Q89KR3	Bradyrhizobium diazoefficiens	LDO
SHEON\|Gene_OrderedLocusName=SO_1656\|UniProtKB=Q8EGE8	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_0270\|UniProtKB=Q9KV86	Vibrio cholerae	O
SALTY\|EnsemblGenome=STM0393\|UniProtKB=Q8ZRE5	Salmonella typhimurium	O
YERPE\|Gene_OrderedLocusName=YPO3211\|UniProtKB=A0A5P8YJC8	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAE78087\|UniProtKB=P32718	Escherichia coli	O
ECOLI\|EnsemblGenome=BAE76175\|UniProtKB=P23917	Escherichia coli	O
VIBCH\|EnsemblGenome=VC_0993\|UniProtKB=Q9KTB0	Vibrio cholerae	O
SALTY\|EnsemblGenome=STM0682\|UniProtKB=Q8ZQX9	Salmonella typhimurium	O
YERPE\|Gene_OrderedLocusName=YPO2625\|UniProtKB=Q0WDQ7	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAA35319\|UniProtKB=P0AF20	Escherichia coli	O
HAEIN\|EnsemblGenome=HI_0182\|UniProtKB=P44554	Haemophilus influenzae	O
VIBCH\|EnsemblGenome=VC_1532\|UniProtKB=Q9KRV2	Vibrio cholerae	O
SALTY\|EnsemblGenome=STM1220\|UniProtKB=Q8ZPZ9	Salmonella typhimurium	O
YERPE\|EnsemblGenome=YP_1758\|UniProtKB=Q0WGE8	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAA35939\|UniProtKB=P75959	Escherichia coli	O
SHEON\|Gene_OrderedLocusName=SO_1389\|UniProtKB=Q8EH41	Shewanella oneidensis	LDO
VIBCH\|EnsemblGenome=VC_2007\|UniProtKB=Q9KQJ1	Vibrio cholerae	LDO
SALTY\|EnsemblGenome=STM1488\|UniProtKB=Q8ZPK7	Salmonella typhimurium	LDO
YERPE\|Gene_OrderedLocusName=YPO2268\|UniProtKB=A0A380PCA0	Yersinia pestis	LDO
ECOLI\|EnsemblGenome=BAA16458\|UniProtKB=P76586	Escherichia coli	O
ECOLI\|EnsemblGenome=BAA15318\|UniProtKB=P50456	Escherichia coli	LDO