The mission of the PANTHER knowledgebase is to support biomedical and other research by providing
comprehensive information about the evolution of protein-coding gene families, particularly
protein phylogeny, function and genetic variation impacting that function. Learn more

PANTHER19.0 Released. Click for more details.

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Current Release: PANTHER 19.0 | 15,683 family phylogenetic trees | 144 species | News
Whole genome function views

PANTHER Gene Information

Gene Symbol(s):

PRSS8

Organism:

Canis lupus familiaris

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Tree

Gene Name:

Serine protease 8

Gene ID:

ENSCAFG00845012186.1

Protein ID:

A0A8I3NLL5

Persistent Id:

PTN001546098

Alternate Ids:

102157328(GeneID)	XM_005621242(refSeq)
545501392(GI)	ENSCAFT00845021669(Ensembl_TRS)
A0A8I3NLL5_CANLF(UniProtKB-ID)	A0A8I3NLL5(Synonym)
ENSCAFP00845017036(Ensembl_PRO)	ENSCAFG00845012186(Ensembl)
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PANTHER Classification

PANTHER Family:	TRANSMEMBRANE PROTEASE SERINE (PTHR24253)
PANTHER Subfamily:	PROSTASIN (PTHR24253:SF169)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	serine protease

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	serine-type endopeptidase activity
GO BP Complete:	proteolysis, positive regulation of sodium ion transport
GO CC Complete:	plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Keratinization, Formation of the cornified envelope, Developmental Biology

Orthologs

ID	Organism	Type
HUMAN\|HGNC=9491\|UniProtKB=Q16651	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000008035.6\|UniProtKB=A0A2J8J541	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000013616.3\|UniProtKB=G3RCP6	Gorilla gorilla gorilla	LDO
MOUSE\|MGI=MGI=1923810\|UniProtKB=Q9ESD1	Mus musculus	LDO
RAT\|RGD=619973\|UniProtKB=Q9ES87	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000016973.5\|UniProtKB=F1MUB9	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000038600.3\|UniProtKB=A0A5G2QSK0	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000013572.4\|UniProtKB=F7BC37	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000002606.6\|UniProtKB=M3VYT9	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000001874.4\|UniProtKB=F6S6A4	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000037319.1\|UniProtKB=A0A6I8NRP8	Ornithorhynchus anatinus	LDO
ANOCA\|Ensembl=ENSACAG00000006748.4\|UniProtKB=H9GBW2	Anolis carolinensis	LDO
XENLA\|Gene=prss8.S\|UniProtKB=O42272	Xenopus laevis	O
XENLA\|Gene=LOC108703949\|UniProtKB=A0A8J0U683	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-5758112\|UniProtKB=Q28EB0	Xenopus tropicalis	LDO
DROME\|FlyBase=FBgn0029827\|UniProtKB=Q9W453	Drosophila melanogaster	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g198217\|UniProtKB=A7RJY0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g127465\|UniProtKB=A7SQF1	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g111870\|UniProtKB=A7SB63	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g130234\|UniProtKB=A7SSR9	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g109826\|UniProtKB=A7S9G1	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g230861\|UniProtKB=A7SSS0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g41116\|UniProtKB=A7SZI9	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g109239\|UniProtKB=A7S8Y5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g88458\|UniProtKB=A7RP61	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g124644\|UniProtKB=A7SNB8	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG61839\|UniProtKB=B3SC39	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG25686\|UniProtKB=B3RY71	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG53235\|UniProtKB=B3RNP0	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG18710\|UniProtKB=B3RIF5	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG5625\|UniProtKB=B3RYJ8	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG26286\|UniProtKB=B3RZF9	Trichoplax adhaerens	O