PANTHER Gene Information

Gene Symbol(s):

ABCC3

Organism:

Canis lupus familiaris

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Tree

Gene Name:

ABC-type glutathione-S-conjugate transporter

Gene ID:

ENSCAFG00845014515.1

Protein ID:

A0A8I3S0X8

Persistent Id:

PTN001200273

Alternate Ids:

A0A8I3S0X8(Synonym)	ENSCAFT00845025981(Ensembl_TRS)
A0A8I3S0X8_CANLF(UniProtKB-ID)	ENSCAFG00845014515(Ensembl)
ENSCAFP00845020480(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	ATP-BINDING CASSETTE SUB-FAMILY C (PTHR24223)
PANTHER Subfamily:	ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 3 (PTHR24223:SF405)
PANTHER GO-slim Molecular Function:	ATPase-coupled transmembrane transporter activity
PANTHER GO-slim Biological Process:	transmembrane transport
PANTHER GO-slim Cellular Component:	membrane
PANTHER protein class:	ATP-binding cassette (ABC) transporter

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	ATP hydrolysis activity, ATP binding, ATPase-coupled transmembrane transporter activity, ABC-type glutathione S-conjugate transporter activity, glucuronoside transmembrane transporter activity, ABC-type xenobiotic transporter activity, icosanoid transmembrane transporter activity
GO BP Complete:	xenobiotic transmembrane transport, leukotriene transport, transmembrane transport, glucuronoside transport
GO CC Complete:	membrane, basolateral plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Recycling of bile acids and salts, ABC-family proteins mediated transport, Paracetamol ADME, Bile acid and bile salt metabolism, Metabolism, Metabolism of steroids, Aspirin ADME, Drug ADME, Transport of small molecules, Metabolism of lipids

Orthologs

ID	Organism	Type
HUMAN\|HGNC=54\|UniProtKB=O15438	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000009406.5\|UniProtKB=K7AAA2	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000003404.3\|UniProtKB=G3QLJ8	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000003414.4\|UniProtKB=F7F9V4	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1923658\|UniProtKB=B2RX12	Mus musculus	LDO
RAT\|RGD=71101\|UniProtKB=O88563	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000020070.6\|UniProtKB=F1N3Y6	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000017561.5\|UniProtKB=A0A5G2R2F8	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000001014.4\|UniProtKB=A0A3Q2H666	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000012340.6\|UniProtKB=M3WGR6	Felis catus	LDO
ORNAN\|Ensembl=ENSOANG00000013332.3\|UniProtKB=A0A6I8NZ47	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010029290.1\|UniProtKB=F1NM51	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000001396.4\|UniProtKB=G1K9J3	Anolis carolinensis	LDO
XENLA\|Gene=abcc3.L\|UniProtKB=A0A1L8EUK3	Xenopus laevis	O
XENLA\|Gene=abcc3.S\|UniProtKB=A0A1L8EN18	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-1003737\|UniProtKB=A9JRK6	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000020741.2\|UniProtKB=H2N2K2	Oryzias latipes	LDO
DANRE\|Gene=abcc3\|UniProtKB=A0A8M3AXY3	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000010918.1\|UniProtKB=W5MYF8	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000006451.3\|UniProtKB=F6PGX9	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118428483\|UniProtKB=A0A9J7N971	Branchiostoma floridae	O
BRAFL\|Gene=LOC118428888\|UniProtKB=A0A9J7N8Y3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118428883\|UniProtKB=A0A9J7M5R8	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=GeneID_591344\|UniProtKB=I0DHH8	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00003408\|UniProtKB=Q20943	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG08146\|UniProtKB=A8X5X4	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00003407\|UniProtKB=Q3S1M2	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG08145\|UniProtKB=A8X5X3	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00110127\|UniProtKB=A0A2A6D320	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0032456\|UniProtKB=Q7KTC0	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP028128\|UniProtKB=A0A1S4HCW9	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP027980\|UniProtKB=A0A1S4HCJ3	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP008437\|UniProtKB=A0A1S4GY97	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP009835\|UniProtKB=A0A1S4H286	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC012253\|UniProtKB=A0A139WC08	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_347281\|UniProtKB=E9H667	Daphnia pulex	LDO
HELRO\|EnsemblGenome=HelroG115686\|UniProtKB=T1EGA0	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG95925\|UniProtKB=T1G989	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG105347\|UniProtKB=T1EDT9	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g10039\|UniProtKB=A7SMJ8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g190171\|UniProtKB=A7SII0	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG31533\|UniProtKB=B3S9C1	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG60846\|UniProtKB=B3S9B5	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG60852\|UniProtKB=B3S9C0	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG50946\|UniProtKB=B3S9B6	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG30988\|UniProtKB=B3S839	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG50060\|UniProtKB=B3RSQ0	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG51152\|UniProtKB=B3SCI9	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_18722\|UniProtKB=A9UX43	Monosiga brevicollis	LDO
EMENI\|EnsemblGenome=ANIA_00015\|UniProtKB=C8VRH1	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_5G00340\|UniProtKB=Q4WDQ9	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU02051\|UniProtKB=Q7SF27	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_11032\|UniProtKB=A7F0B5	Sclerotinia sclerotiorum	O
SCLS1\|EnsemblGenome=SS1G_05336\|UniProtKB=A7EJ43	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_00757\|UniProtKB=Q0V5F7	Phaeosphaeria nodorum	O
EMENI\|EnsemblGenome=ANIA_08150\|UniProtKB=Q5AU80	Emericella nidulans	O
EMENI\|EnsemblGenome=ANIA_07839\|UniProtKB=C8VDW5	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_5G12720\|UniProtKB=Q4WVN3	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU03776\|UniProtKB=F5HEB1	Neurospora crassa	O
EMENI\|EnsemblGenome=ANIA_07879\|UniProtKB=Q5AV01	Emericella nidulans	O
PHANO\|EnsemblGenome=SNOG_14100\|UniProtKB=Q0U1T8	Phaeosphaeria nodorum	O
PHANO\|EnsemblGenome=SNOG_09087\|UniProtKB=Q0UGM7	Phaeosphaeria nodorum	O
EMENI\|EnsemblGenome=ANIA_01240\|UniProtKB=Q5BDZ0	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_1G10390\|UniProtKB=Q4WT65	Neosartorya fumigata	O
SCLS1\|EnsemblGenome=SS1G_03324\|UniProtKB=A7EDD4	Sclerotinia sclerotiorum	O
SCLS1\|EnsemblGenome=SS1G_13112\|UniProtKB=A7F683	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_01112\|UniProtKB=Q0V4F2	Phaeosphaeria nodorum	O
PHANO\|EnsemblGenome=SNOG_14836\|UniProtKB=Q0TZX9	Phaeosphaeria nodorum	O
USTMA\|EnsemblGenome=UMAG_01758\|UniProtKB=A0A0D1CBL8	Ustilago maydis	O
USTMA\|EnsemblGenome=UMAG_15074\|UniProtKB=A0A0D1CW46	Ustilago maydis	O
USTMA\|EnsemblGenome=UMAG_05794\|UniProtKB=A0A0D1BZ25	Ustilago maydis	O
USTMA\|EnsemblGenome=UMAG_15032\|UniProtKB=A0A0D1CSJ1	Ustilago maydis	O
YEAST\|SGD=S000003938\|UniProtKB=P14772	Saccharomyces cerevisiae	O
YEAST\|SGD=S000002542\|UniProtKB=P39109	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AGR047W\|UniProtKB=Q750B0	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000183742\|UniProtKB=A0A1D8PTN6	Candida albicans	O
CANAL\|CGD=CAL0000178329\|UniProtKB=Q5A762	Candida albicans	O
CANAL\|CGD=CAL0000179549\|UniProtKB=A0A1D8PR42	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_E08969g\|UniProtKB=Q6C6J9	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_F31845g\|UniProtKB=Q6BZQ2	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_A19580g\|UniProtKB=Q6CGG4	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_C18051g\|UniProtKB=Q6CBK3	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_F12089g\|UniProtKB=Q6C1Z6	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_E25069g\|UniProtKB=Q6C4N2	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_03472\|UniProtKB=Q5B7K8	Emericella nidulans	O
EMENI\|EnsemblGenome=ANIA_07729\|UniProtKB=Q5AVF1	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_5G07970\|UniProtKB=Q4WUC5	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU09012\|UniProtKB=Q7S0S1	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_07453\|UniProtKB=A7EQ53	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_09278\|UniProtKB=Q0UG36	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPBC359.05\|UniProtKB=Q9P5N0	Schizosaccharomyces pombe	O
SCHPO\|PomBase=SPAC3F10.11c\|UniProtKB=Q10185	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_01344\|UniProtKB=B6K0F0	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNC05860\|UniProtKB=Q5KJN9	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_10365\|UniProtKB=A0A0D1DYC7	Ustilago maydis	O
USTMA\|EnsemblGenome=UMAG_02568\|UniProtKB=A0A0D1E417	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_14463\|UniProtKB=E3KVN9	Puccinia graminis	LDO
PUCGT\|EnsemblGenome=PGTG_14456\|UniProtKB=E3KVN2	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_9753\|UniProtKB=F4NVY7	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_14605\|UniProtKB=F4PDI2	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_88614\|UniProtKB=F4P3J1	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_18172\|UniProtKB=F4NRK4	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_92730\|UniProtKB=F4PEH2	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_20822\|UniProtKB=F4PBV3	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_18633\|UniProtKB=F4NTL2	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_16805\|UniProtKB=F4P4C1	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_124840\|UniProtKB=C4M978	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0284867\|UniProtKB=Q54P13	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_47315\|UniProtKB=F0ZIX3	Dictyostelium purpureum	LDO
PARTE\|EnsemblGenome=GSPATT00001809001\|UniProtKB=A0D6V1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00028165001\|UniProtKB=A0BF13	Paramecium tetraurelia	LDO
PHYRM\|Gene=H3HEF0_PHYRM\|UniProtKB=H3HEF0	Phytophthora ramorum	O
PHYRM\|Gene=H3HCF6_PHYRM\|UniProtKB=H3HCF6	Phytophthora ramorum	O
PHYRM\|Gene=H3HD40_PHYRM\|UniProtKB=H3HD40	Phytophthora ramorum	O
PHYRM\|Gene=H3HE07_PHYRM\|UniProtKB=H3HE07	Phytophthora ramorum	O
PHYRM\|Gene=H3GAE6_PHYRM\|UniProtKB=H3GAE6	Phytophthora ramorum	O
PHYRM\|Gene=H3HD38_PHYRM\|UniProtKB=H3HD38	Phytophthora ramorum	O
PHYRM\|Gene=H3H408_PHYRM\|UniProtKB=H3H408	Phytophthora ramorum	O
PHYRM\|Gene=H3GKM1_PHYRM\|UniProtKB=H3GKM1	Phytophthora ramorum	O
PHYRM\|Gene=H3GJD8_PHYRM\|UniProtKB=H3GJD8	Phytophthora ramorum	O
PHYRM\|Gene=H3H2W5_PHYRM\|UniProtKB=H3H2W5	Phytophthora ramorum	O
PHYRM\|Gene=H3H5U8_PHYRM\|UniProtKB=H3H5U8	Phytophthora ramorum	O
PHYRM\|Gene=H3HE89_PHYRM\|UniProtKB=H3HE89	Phytophthora ramorum	O
PHYRM\|Gene=H3GAR7_PHYRM\|UniProtKB=H3GAR7	Phytophthora ramorum	O
PHYRM\|Gene=H3G9K9_PHYRM\|UniProtKB=H3G9K9	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_08g369720v5\|UniProtKB=A0A2K3DH39	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_07g325761v5\|UniProtKB=A0A2K3DJI3	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_08g369850v5\|UniProtKB=A0A2K3DH80	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_03g174050v5\|UniProtKB=A0A2K3DX98	Chlamydomonas reinhardtii	O
KLENI\|Gene_ORFName=KFL_003420130\|UniProtKB=A0A1Y1I8H3	Klebsormidium nitens	O
CHLRE\|EnsemblGenome=CHLRE_02g097800v5\|UniProtKB=A0A2K3E226	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_17g734612v5\|UniProtKB=Q50JT7	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_13g564900v5\|UniProtKB=A0A2K3CZ64	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_02g103250v5\|UniProtKB=A0A2K3E2F8	Chlamydomonas reinhardtii	LDO
MARPO\|EnsemblGenome=MARPO_0133s0051\|UniProtKB=A0A2R6W7S7	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_004930030\|UniProtKB=A0A1Y1IDX7	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_000850340\|UniProtKB=A0A1Y1I0J0	Klebsormidium nitens	LDO