PANTHER Gene Information   
Gene Symbol(s): CNOT7
Organism: Canis lupus familiaris
View Gene in Tree
Tree
Tree
Gene Name: poly(A)-specific ribonuclease
Gene ID: ENSCAFG00845014580.1
Protein ID: A0A8I3NXC2
Persistent Id: PTN000084136
Alternate Ids:
482895(GeneID) A0A8I3NXC2_CANLF(UniProtKB-ID)
ENSCAFT00845026093(Ensembl_TRS) ENSCAFP00845020574(Ensembl_PRO)
ENSCAFG00845014580(Ensembl) A0A8I3NXC2(Synonym)
XP_540010(refSeq) 73979407(GI)
Show All

PANTHER Classification
PANTHER Family: CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT (PTHR10797)
PANTHER Subfamily: CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 7 (PTHR10797:SF79)  
PANTHER GO-slim Molecular Function: 3'-5'-RNA exonuclease activity
PANTHER GO-slim Biological Process: nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
PANTHER GO-slim Cellular Component: CCR4-NOT complex
P-body
PANTHER protein class: mRNA polyadenylation factor
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: poly(A)-specific ribonuclease activity, transcription corepressor activity, piRNA binding, DNA-binding transcription factor binding
GO BP Complete: positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, negative regulation of cell population proliferation, positive regulation of cell population proliferation, negative regulation of type I interferon-mediated signaling pathway, positive regulation of transcription by RNA polymerase II, positive regulation of nuclear-transcribed mRNA poly(A) tail shortening, nuclear-transcribed mRNA poly(A) tail shortening, nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, negative regulation of DNA-templated transcription, deadenylation-dependent decapping of nuclear-transcribed mRNA, P-body assembly, defense response to virus, miRNA-mediated gene silencing by mRNA destabilization, positive regulation of viral genome replication, piRNA-mediated gene silencing by mRNA destabilization
GO CC Complete: nuclear speck, P-body, CCR4-NOT core complex, CCR4-NOT complex
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Gene expression (Transcription), Generic Transcription Pathway, Metabolism of RNA, TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain, Transcriptional Regulation by TP53, RNA Polymerase II Transcription, TP53 Regulates Transcription of Cell Cycle Genes, Deadenylation-dependent mRNA decay, Deadenylation of mRNA

Orthologs