PANTHER Gene Information   
Gene Symbol(s): FGF22
Organism: Canis lupus familiaris
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Gene Name: Fibroblast growth factor
Gene ID: ENSCAFG00845014846.1
Protein ID: A0A8I3NYK3
Persistent Id: PTN001352980
Alternate Ids:
ENSCAFG00845014846(Ensembl) A0A8I3NYK3(Synonym)
612404(GeneID) 359322169(GI)
ENSCAFT00845026556(Ensembl_TRS) ENSCAFP00845020935(Ensembl_PRO)
XP_855230(refSeq) A0A8I3NYK3_CANLF(UniProtKB-ID)
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PANTHER Classification
PANTHER Family: FIBROBLAST GROWTH FACTOR (PTHR11486)
PANTHER Subfamily: FIBROBLAST GROWTH FACTOR 22 (PTHR11486:SF41)  
PANTHER GO-slim Molecular Function: growth factor activity
fibroblast growth factor receptor binding
PANTHER GO-slim Biological Process: regulation of cell migration
fibroblast growth factor receptor signaling pathway
positive regulation of protein phosphorylation
cell differentiation
positive regulation of MAPK cascade
positive regulation of gene expression
positive regulation of cell population proliferation
animal organ morphogenesis
PANTHER GO-slim Cellular Component: extracellular space
cytoplasm
PANTHER protein class: growth factor
Pathway Categories: FGF signaling pathway
   fibroblast growth factor

GO MF Complete: growth factor activity, fibroblast growth factor receptor binding
GO BP Complete: signal transduction, positive regulation of cell population proliferation, fibroblast growth factor receptor signaling pathway, neurogenesis, positive regulation of MAPK cascade, regulation of cell migration
GO CC Complete: cytoplasm
Reactome Pathways: PI3K Cascade, Downstream signaling of activated FGFR1, FGFRL1 modulation of FGFR1 signaling, SHC-mediated cascade:FGFR1, PI-3K cascade:FGFR1, FRS-mediated FGFR2 signaling, IRS-related events triggered by IGF1R, Insulin receptor signalling cascade, Signaling by Insulin receptor, FGFR1b ligand binding and activation, IGF1R signaling cascade, Phospholipase C-mediated cascade; FGFR2, RAF/MAP kinase cascade, FGFR2b ligand binding and activation, Signaling by FGFR, Signaling by Receptor Tyrosine Kinases, Negative regulation of FGFR2 signaling, MAPK1/MAPK3 signaling, Negative regulation of FGFR1 signaling, IRS-mediated signalling, PI-3K cascade:FGFR2, Downstream signaling of activated FGFR2, SHC-mediated cascade:FGFR2, FRS-mediated FGFR1 signaling, PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling, Signal Transduction, PIP3 activates AKT signaling, FGFR2 ligand binding and activation, Intracellular signaling by second messengers, FGFR1 ligand binding and activation, Signaling by FGFR2, Phospholipase C-mediated cascade: FGFR1, Signaling by FGFR1, Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R), Negative regulation of the PI3K/AKT network, MAPK family signaling cascades