PANTHER Gene Information

Gene Symbol(s):

KLHL8

Organism:

Canis lupus familiaris

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Gene Name:

Kelch like family member 8

Gene ID:

ENSCAFG00845015090.1

Protein ID:

A0A8I3S1A8

Persistent Id:

PTN000723237

Alternate Ids:

ENSCAFP00845021263(Ensembl_PRO)	XM_544969(refSeq)
ENSCAFG00845015090(Ensembl)	74001833(GI)
ENSCAFT00845027022(Ensembl_TRS)	A0A8I3S1A8(Synonym)
A0A8I3S1A8_CANLF(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	KELCH PROTEIN (PTHR24412)
PANTHER Subfamily:	KELCH-LIKE PROTEIN 8 (PTHR24412:SF480)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	scaffold/adaptor protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	ubiquitin-like ligase-substrate adaptor activity
GO BP Complete:	proteasome-mediated ubiquitin-dependent protein catabolic process, ubiquitin-dependent protein catabolic process, protein ubiquitination
GO CC Complete:	cytoplasm, Cul3-RING ubiquitin ligase complex, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=18644\|UniProtKB=Q9P2G9	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000016256.4\|UniProtKB=H2QPU7	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000014648.3\|UniProtKB=G3RFC6	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000014080.4\|UniProtKB=F7CE33	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2179430\|UniProtKB=P59280	Mus musculus	LDO
RAT\|RGD=1304685\|UniProtKB=A0A0G2JYB7	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000002455.5\|UniProtKB=E1BPB7	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00005021822.1\|UniProtKB=A0A4X1U1F7	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000017829.4\|UniProtKB=A0A3Q2HKX8	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000013928.6\|UniProtKB=M3WJR6	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000020741.4\|UniProtKB=F7A032	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000013625.4\|UniProtKB=F7F9X1	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010003816.1\|UniProtKB=A0A8V0XEQ2	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000012252.4\|UniProtKB=G1KM60	Anolis carolinensis	LDO
XENLA\|Gene=klhl8.L\|UniProtKB=A0A1L8HVJ1	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-995628\|UniProtKB=Q28D69	Xenopus tropicalis	LDO
DANRE\|ZFIN=ZDB-GENE-070209-226\|UniProtKB=A2RRV4	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000004119.1\|UniProtKB=W5M984	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118419206\|UniProtKB=A0A9J7LEL9	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC575978\|UniProtKB=A0A7M7NT30	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115929072\|UniProtKB=A0A7M7PNY1	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC593632\|UniProtKB=A0A7M7N6G0	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC589135\|UniProtKB=A0A7M7SWM9	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00018563\|UniProtKB=Q09563	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00002186\|UniProtKB=P34569	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG13307\|UniProtKB=A8XHJ2	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00004972\|UniProtKB=Q10579	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG05722\|UniProtKB=A8X1T1	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00020952\|UniProtKB=G5ED84	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00028887\|UniProtKB=A8X2R0	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00277544\|UniProtKB=A0A2A6CGL4	Pristionchus pacificus	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_319466\|UniProtKB=E9GLU4	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW011594\|UniProtKB=B7Q5Q2	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW023716\|UniProtKB=B7QI58	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG190504\|UniProtKB=T1FS19	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG188549\|UniProtKB=T1FQ40	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g227865\|UniProtKB=A7RFM5	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG51845\|UniProtKB=B3RL18	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_9838\|UniProtKB=A9V4D8	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_33009\|UniProtKB=A9V301	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_10631\|UniProtKB=A9V6H8	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_12785\|UniProtKB=A9VDB0	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_27682\|UniProtKB=A9V603	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_10923\|UniProtKB=A9V7M9	Monosiga brevicollis	O
DICDI\|dictyBase=DDB_G0271372\|UniProtKB=Q55BF8	Dictyostelium discoideum	O
TRYB2\|Gene_ORFName=Tb927.6.3010\|UniProtKB=Q583N3	Trypanosoma brucei	O
PLAF7\|EnsemblGenome=PF3D7_1343700\|UniProtKB=Q8IDQ2	Plasmodium falciparum	O
PLAF7\|EnsemblGenome=PF3D7_0724800\|UniProtKB=Q8IBK3	Plasmodium falciparum	O
PARTE\|EnsemblGenome=GSPATT00036896001\|UniProtKB=A0CBE6	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00015318001\|UniProtKB=A0DBK5	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00007376001\|UniProtKB=A0CGL9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00027219001\|UniProtKB=A0EHV1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00006162001\|UniProtKB=A0C0J2	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00020658001\|UniProtKB=A0DVC7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00024750001\|UniProtKB=A0E9Q2	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_9460\|UniProtKB=B8CBE0	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_24961\|UniProtKB=B8CD12	Thalassiosira pseudonana	O
PHYRM\|Gene=H3GWP7_PHYRM\|UniProtKB=H3GWP7	Phytophthora ramorum	O