PANTHER Gene Information

Gene Symbol(s):

CIR1

Organism:

Canis lupus familiaris

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Gene Name:

Corepressor interacting with RBPJ, CIR1

Gene ID:

ENSCAFG00845015697.1

Protein ID:

A0A8I3NM61

Persistent Id:

PTN008345692

Alternate Ids:

A0A8I3NM61_CANLF(UniProtKB-ID)	A0A8I3NM61(Synonym)
ENSCAFG00845015697(Ensembl)	ENSCAFP00845022029(Ensembl_PRO)
ENSCAFT00845027989(Ensembl_TRS)
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PANTHER Classification

PANTHER Family:	CBF1 INTERACTING COREPRESSOR CIR (PTHR13151)
PANTHER Subfamily:	COREPRESSOR INTERACTING WITH RBPJ 1 (PTHR13151:SF2)
PANTHER GO-slim Molecular Function:	transcription corepressor activity
PANTHER GO-slim Biological Process:	negative regulation of DNA-templated transcription
PANTHER GO-slim Cellular Component:	nucleus
PANTHER protein class:

Pathway Categories:

Notch signaling pathway

Co-repressors

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	protein kinase binding, histone deacetylase binding, transcription corepressor activity, protein-containing complex binding
GO BP Complete:	negative regulation of transcription by RNA polymerase II, negative regulation of DNA-templated transcription, in utero embryonic development
GO CC Complete:	nucleus, centrosome, nuclear speck, protein-containing complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=24217\|UniProtKB=Q86X95	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000012652.7\|UniProtKB=K7AK75	Pan troglodytes	LDO
MACMU\|Ensembl=ENSMMUG00000023006.4\|UniProtKB=F6TI81	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1914185\|UniProtKB=Q9DA19	Mus musculus	LDO
RAT\|RGD=1309199\|UniProtKB=Q5U2T8	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000038620.3\|UniProtKB=A0A3Q1MAP6	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000027516.3\|UniProtKB=I3L936	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000006773.3\|UniProtKB=F7CSE9	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000022845.4\|UniProtKB=M3WZB1	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000037714.1\|UniProtKB=A0A5F8GZE1	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000037110.1\|UniProtKB=A0A6I8NS54	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010022585\|UniProtKB=Q5ZI03	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000044316.1\|UniProtKB=A0A803STW8	Anolis carolinensis	LDO
XENLA\|Gene=cir1.L\|UniProtKB=A0A1L8EW84	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-985440\|UniProtKB=A0A6I8QIR8	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000017496.3\|UniProtKB=H2MSY4	Oryzias latipes	LDO
DANRE\|Gene=si=ch73-167c12.2\|UniProtKB=A0A8M9PSH9	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000007371.1\|UniProtKB=W5MKM8	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118424924\|UniProtKB=A0A9J7LV08	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC589977\|UniProtKB=A0A7M7GLT6	Strongylocentrotus purpuratus	LDO
STRPU\|EnsemblGenome=LOC115918013\|UniProtKB=A0A7M7PCN6	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00018892\|UniProtKB=G5EBE3	Caenorhabditis elegans	LDO
PRIPA\|EnsemblGenome=WBGene00274059\|UniProtKB=A0A2A6BNX3	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0036827\|UniProtKB=Q9VVU4	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP004952\|UniProtKB=Q7Q7Y6	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC012381\|UniProtKB=D6X1Z0	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_270484\|UniProtKB=E9I0T0	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_305123\|UniProtKB=E9HVF1	Daphnia pulex	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_117487\|UniProtKB=E9HSU4	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW010369\|UniProtKB=A0A1S4L8L8	Ixodes scapularis	LDO
TRIAD\|EnsemblGenome=TriadG54065\|UniProtKB=B3RR05	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_10588\|UniProtKB=A9V6T8	Monosiga brevicollis	LDO
DICDI\|dictyBase=DDB_G0284007\|UniProtKB=Q54QA7	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_158579\|UniProtKB=F1A1Y3	Dictyostelium purpureum	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_934\|UniProtKB=B8BSV4	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GT93_PHYRM\|UniProtKB=H3GT93	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_06g280700v5\|UniProtKB=A0A2K3DPL2	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00011p00259480\|UniProtKB=W1NH02	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_49G01150\|UniProtKB=A0A0K9NYZ5	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma01_g18650\|UniProtKB=A0A804HVP1	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_006140mg\|UniProtKB=K3XW32	Setaria italica	LDO
MAIZE\|EnsemblGenome=Zm00001eb395460\|UniProtKB=A0A1D6PBH8	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb227500\|UniProtKB=A0A804PD16	Zea mays	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.7HG0725720\|UniProtKB=A0A8I6YHU7	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS7A02G408900\|UniProtKB=A0A3B6RNM9	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7D02G402200\|UniProtKB=A0A3B6TVY3	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7B02G308700\|UniProtKB=A0A3B6SJX0	Triticum aestivum	LDO
NELNU\|Gene_ORFName=HUJ06_001521\|UniProtKB=A0A1U7ZT72	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110796350\|UniProtKB=A0A9R0IWZ1	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr07g0286731\|UniProtKB=A0A251UC39	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C600305400\|UniProtKB=A0A9R1VC06	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a006679mg\|UniProtKB=A0A022QPA3	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_01044\|UniProtKB=A0A2G3AFZ8	Capsicum annuum	LDO
SOLLC\|EnsemblGenome=Solyc08g075420.3\|UniProtKB=A0A3Q7HQL5	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107819323\|UniProtKB=A0A1S4CIS3	Nicotiana tabacum	LDO
TOBAC\|Gene=LOC107792268\|UniProtKB=A0A1S4A026	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi02g01278\|UniProtKB=D7TFB6	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_D02560\|UniProtKB=A0A059CKD8	Eucalyptus grandis	LDO
BRACM\|EnsemblGenome=Bra013381\|UniProtKB=M4DA71	Brassica campestris	LDO
ARATH\|TAIR=locus=2134741\|UniProtKB=Q8VZ67	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107929455\|UniProtKB=A0A1U8LP63	Gossypium hirsutum	O
GOSHI\|Gene=LOC107900685\|UniProtKB=A0A1U8IUS2	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_016691\|UniProtKB=A0A061GE82	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g046722mg\|UniProtKB=A0A067FY08	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_004G236300v3\|UniProtKB=U5GHI2	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_17G000100\|UniProtKB=A0A2C9U394	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0867880\|UniProtKB=B9S1S8	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_11G090300\|UniProtKB=I1LIF8	Glycine max	LDO
SOYBN\|EnsemblGenome=GLYMA_01G154300\|UniProtKB=I1J883	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_2g040410\|UniProtKB=G7IQB2	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr02_11410\|UniProtKB=A0A2I4E5A7	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_4G358660\|UniProtKB=A0A0A0KYH9	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_1G353400\|UniProtKB=A0A251R843	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_416934\|UniProtKB=D8S0V1	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_420276\|UniProtKB=D8SBH2	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c3_31660\|UniProtKB=A9S8A8	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0190s0006\|UniProtKB=A0A2R6W168	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_000910230\|UniProtKB=A0A1Y1HUJ6	Klebsormidium nitens	LDO