PANTHER Gene Information

Gene Symbol(s):

CPOX

Organism:

Canis lupus familiaris

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Gene Name:

coproporphyrinogen oxidase

Gene ID:

ENSCAFG00845016323.1

Protein ID:

A0A8I3NZN6

Persistent Id:

PTN008952539

Alternate Ids:

ENSCAFT00845029022(Ensembl_TRS)	A0A8I3NZN6(Synonym)
ENSCAFG00845016323(Ensembl)	ENSCAFP00845022844(Ensembl_PRO)
A0A8I3NZN6_CANLF(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	COPROPORPHYRINOGEN III OXIDASE, MITOCHONDRIAL (PTHR10755)
PANTHER Subfamily:	OXYGEN-DEPENDENT COPROPORPHYRINOGEN-III OXIDASE, MITOCHONDRIAL (PTHR10755:SF0)
PANTHER GO-slim Molecular Function:	oxidoreductase activity, acting on the CH-CH group of donors
PANTHER GO-slim Biological Process:	heme biosynthetic process
PANTHER GO-slim Cellular Component:	cytoplasm
PANTHER protein class:	oxidase

Pathway Categories:

Heme biosynthesis

Coproporphyrinogen Oxidase (oxygen dependent)

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	protein homodimerization activity, coproporphyrinogen oxidase activity, structural constituent of eye lens
GO BP Complete:	heme O biosynthetic process, heme A biosynthetic process, protoporphyrinogen IX biosynthetic process, heme B biosynthetic process
GO CC Complete:	mitochondrial intermembrane space, cytoplasm, membrane, cytosol

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Heme biosynthesis, Metabolism of porphyrins, Metabolism

Orthologs

ID	Organism	Type
HUMAN\|HGNC=2321\|UniProtKB=P36551	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000015151.4\|UniProtKB=H2QMZ9	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000014315.3\|UniProtKB=G3REH3	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000065045.1\|UniProtKB=A0A5F7Z781	Macaca mulatta	LDO
MOUSE\|MGI=MGI=104841\|UniProtKB=P36552	Mus musculus	LDO
RAT\|RGD=1311817\|UniProtKB=Q3B7D0	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000004124.6\|UniProtKB=E1BKY9	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000011978.4\|UniProtKB=F1SK95	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000016542.3\|UniProtKB=A0A9L0R251	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000040516.2\|UniProtKB=A0A337S4W4	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000017065.3\|UniProtKB=F6XHE8	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000007535.4\|UniProtKB=F6TJW1	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010005386.1\|UniProtKB=A0A8V0XKY4	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000010834.4\|UniProtKB=G1KKL4	Anolis carolinensis	LDO
XENLA\|Gene=cpox.L\|UniProtKB=A0A8J1M744	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-950297\|UniProtKB=F6QTP1	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000005599.2\|UniProtKB=H2LLX1	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-030131-9884\|UniProtKB=Q05AK3	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000010105.1\|UniProtKB=W5MVF6	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000010096.1\|UniProtKB=W5MVE3	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000010115.1\|UniProtKB=W5MVH8	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118409718\|UniProtKB=A0A9J7KMS2	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC580851\|UniProtKB=A0A7M7PFR4	Strongylocentrotus purpuratus	LDO
DROME\|FlyBase=FBgn0021944\|UniProtKB=Q9V3D2	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP004749\|UniProtKB=Q7Q2P4	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC000466\|UniProtKB=D6WA50	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_111417\|UniProtKB=E9H941	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW010977\|UniProtKB=B7Q9Z2	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG86324\|UniProtKB=T1G6A4	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g229388\|UniProtKB=A7S4S5	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG50218\|UniProtKB=B3RVP9	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG25736\|UniProtKB=B3RYM5	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_28565\|UniProtKB=A9V8J6	Monosiga brevicollis	LDO
YEAST\|SGD=S000002451\|UniProtKB=P11353	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AGR030C\|UniProtKB=Q750C5	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000191428\|UniProtKB=Q59MR4	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_E29975g\|UniProtKB=Q6C438	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_05130\|UniProtKB=C8VEZ2	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_1G07480\|UniProtKB=Q4WJ26	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU01546\|UniProtKB=F5H9D4	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_01603\|UniProtKB=A7E8H5	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_01276\|UniProtKB=Q0V3Y8	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPAC222.11\|UniProtKB=Q9UTE2	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_04944\|UniProtKB=B6K867	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNE00980\|UniProtKB=Q5KH76	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_12186\|UniProtKB=A0A0D1CTF5	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_19445\|UniProtKB=E3L9I1	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_13553\|UniProtKB=F4PAD7	Batrachochytrium dendrobatidis	LDO
DICDI\|dictyBase=DDB_G0288893\|UniProtKB=Q54IA7	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_91609\|UniProtKB=F0ZES7	Dictyostelium purpureum	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_38022\|UniProtKB=B8CE15	Thalassiosira pseudonana	O
CHLRE\|EnsemblGenome=CHLRE_02g092600v5\|UniProtKB=Q4U0V8	Chlamydomonas reinhardtii	O
PHYPA\|EnsemblGenome=Pp3c15_4200\|UniProtKB=A0A2K1JBU4	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0070s0075\|UniProtKB=A0A2R6WP43	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_003010100\|UniProtKB=A0A1Y1I6Q2	Klebsormidium nitens	O
PLAF7\|EnsemblGenome=PF3D7_1142400\|UniProtKB=Q8IHU1	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00016653001\|UniProtKB=A0DFM3	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00007017001\|UniProtKB=A0CDD9	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_31012\|UniProtKB=B8BSK1	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GIT7_PHYRM\|UniProtKB=H3GIT7	Phytophthora ramorum	O
PHYRM\|Gene=H3GIT6_PHYRM\|UniProtKB=H3GIT6	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_02g085450v5\|UniProtKB=Q9S7V1	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00032p00226710\|UniProtKB=U5CPA6	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_69G00410\|UniProtKB=A0A0K9NRD5	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma02_g04400\|UniProtKB=A0A804HZ65	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma03_g24960\|UniProtKB=A0A804IFZ6	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma11_g23950\|UniProtKB=A0A804LBC0	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_014020mg\|UniProtKB=K3YIF1	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3007G076700\|UniProtKB=C5YIV3	Sorghum bicolor	O
BRADI\|EnsemblGenome=BRADI_3g18051v3\|UniProtKB=A0A2K2CY03	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0591920\|UniProtKB=F2E3Y4	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS6A02G213400\|UniProtKB=A0A3B6NP27	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6B02G243500\|UniProtKB=A0A3B6PKH8	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7B02G234200\|UniProtKB=A0A3B6SIH7	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6D02G196100\|UniProtKB=A0A3B6QHK8	Triticum aestivum	O
SETIT\|EnsemblGenome=SETIT_010291mg\|UniProtKB=K3Y7V0	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3006G210800\|UniProtKB=C5YFN1	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb071140\|UniProtKB=B4F938	Zea mays	LDO
ORYSJ\|Gene_OrderedLocusName=LOC_Os04g52130\|UniProtKB=Q7XPL2	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_5g21310v3\|UniProtKB=I1J1N0	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.2HG0191580\|UniProtKB=F2DIZ2	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS2D02G425000\|UniProtKB=A0A1D5UJW2	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2A02G426900\|UniProtKB=A0A3B6B3A4	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2B02G447300\|UniProtKB=A0A3B6CBS1	Triticum aestivum	LDO
NELNU\|Gene_ORFName=HUJ06_002319\|UniProtKB=A0A1U8AEP7	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110782475\|UniProtKB=A0A9R0JQ11	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr03g0133711\|UniProtKB=A0A251VAW4	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C300146280\|UniProtKB=A0A9R1XK09	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a007523mg\|UniProtKB=A0A022RSW5	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_25172\|UniProtKB=A0A1U8EMR2	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400011264\|UniProtKB=M1ASK9	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc10g005110.3\|UniProtKB=A0A3Q7I9A2	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107766888\|UniProtKB=A0A1S3XMU0	Nicotiana tabacum	O
TOBAC\|Gene=CPX\|UniProtKB=Q42946	Nicotiana tabacum	O
TOBAC\|Gene=LOC107815524\|UniProtKB=A0A1S4C5X4	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi03g01309\|UniProtKB=F6HTQ1	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_K01354\|UniProtKB=A0A059A1C4	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_A09P68290.1\|UniProtKB=A0A078H525	Brassica napus	O
BRACM\|EnsemblGenome=Bra032550\|UniProtKB=M4EUR8	Brassica campestris	O
BRANA\|Gene_ORFName=GSBRNA2T00063998001\|UniProtKB=A0A078HI52	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_C05P01960.1\|UniProtKB=A0A078JF82	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra033402\|UniProtKB=M4EX67	Brassica campestris	LDO
ARATH\|TAIR=locus=2825062\|UniProtKB=Q9LR75	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107897850\|UniProtKB=A0A1U8ILD6	Gossypium hirsutum	O
GOSHI\|Gene=LOC107912651\|UniProtKB=A0A1U8K623	Gossypium hirsutum	O
GOSHI\|Gene=LOC107955637\|UniProtKB=A0A1U8P6U4	Gossypium hirsutum	O
GOSHI\|Gene=LOC107915439\|UniProtKB=A0A1U8KC85	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_002076\|UniProtKB=A0A061DKP9	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g014082mg\|UniProtKB=A0A067EH25	Citrus sinensis	LDO
POPTR\|Gene_ORFName=POPTR_011G023900\|UniProtKB=A0A3N7FPR8	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_16G000600\|UniProtKB=A0A2C9U752	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0902640\|UniProtKB=B9RXC7	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_14G003200\|UniProtKB=A0A0R0G797	Glycine max	LDO
SOYBN\|Gene=CPX\|UniProtKB=P35055	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_5g098800\|UniProtKB=G7KFC7	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr16_00190\|UniProtKB=A0A2I4G3Y1	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_4G056670\|UniProtKB=A0A0A0KYN2	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_3G183400\|UniProtKB=M5XBN6	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_131328\|UniProtKB=D8T3V0	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c21_600\|UniProtKB=A0A2K1IQ90	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c22_5800\|UniProtKB=A9RJD1	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0039s0053\|UniProtKB=A0A2R6X395	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_000750090\|UniProtKB=A0A0U9HS61	Klebsormidium nitens	LDO
CHLAA\|EnsemblGenome=Caur_2599\|UniProtKB=A9WIS8	Chloroflexus aurantiacus	LDO
GLOVI\|EnsemblGenome=BAC91817\|UniProtKB=Q7NEK3	Gloeobacter violaceus	LDO
SYNY3\|EnsemblGenome=BAA16863\|UniProtKB=P72848	Synechocystis	LDO
BRADU\|EnsemblGenome=BAC47746\|UniProtKB=Q89SC2	Bradyrhizobium diazoefficiens	LDO
COXBU\|EnsemblGenome=CBU_1729\|UniProtKB=Q83AZ6	Coxiella burnetii	LDO
SHEON\|Gene_OrderedLocusName=SO_0038\|UniProtKB=Q8EKQ2	Shewanella oneidensis	LDO
VIBCH\|EnsemblGenome=VC_0055\|UniProtKB=Q9KVT4	Vibrio cholerae	LDO
XANCP\|EnsemblGenome=XCC4019\|UniProtKB=Q8P3Q0	Xanthomonas campestris	LDO
PSEAE\|EnsemblGenome=PA0024\|UniProtKB=P43898	Pseudomonas aeruginosa	LDO
SALTY\|EnsemblGenome=STM2451\|UniProtKB=P33771	Salmonella typhimurium	LDO
YERPE\|EnsemblGenome=YP_2655\|UniProtKB=Q8ZCF9	Yersinia pestis	LDO
ECOLI\|EnsemblGenome=BAA16319\|UniProtKB=P36553	Escherichia coli	LDO