PANTHER Gene Information

Gene Symbol(s):

CLDN2

Organism:

Canis lupus familiaris

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Gene Name:

Claudin 2

Gene ID:

ENSCAFG00845017181.1

Protein ID:

A0A8I3P3D1

Persistent Id:

PTN008988323

Alternate Ids:

ENSCAFT00845030393(Ensembl_TRS)	A0A8I3P3D1(Synonym)
928183631(GI)	ENSCAFG00845017181(Ensembl)
ENSCAFP00845023836(Ensembl_PRO)	XP_013966788(refSeq)
A0A8I3P3D1_CANLF(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	CLAUDIN (PTHR12002)
PANTHER Subfamily:	CLAUDIN-2 (PTHR12002:SF110)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	cell-cell junction assembly cell-cell adhesion via plasma-membrane adhesion molecules
PANTHER GO-slim Cellular Component:	plasma membrane bicellular tight junction
PANTHER protein class:	tight junction

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	identical protein binding, structural molecule activity, paracellular tight junction channel activity
GO BP Complete:	regulation of bile acid secretion, calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules, innate immune response in mucosa, regulation of intestinal lipid absorption, bicellular tight junction assembly, paracellular transport, regulation of intestinal D-glucose absorption
GO CC Complete:	bicellular tight junction, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=2041\|UniProtKB=P57739	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000022156.3\|UniProtKB=A0A2J8K3N3	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000038544.1\|UniProtKB=A0A2I2Y2X0	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000013146.4\|UniProtKB=F6Z8S4	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1276110\|UniProtKB=O88552	Mus musculus	LDO
RAT\|RGD=1560247\|UniProtKB=D4A386	Rattus norvegicus	LDO
BOVIN\|Gene=CLDN2\|UniProtKB=Q765P1	Bos taurus	LDO
BOVIN\|Ensembl=ENSBTAG00000055282.1\|UniProtKB=A0A3Q1LTB5	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00005012455.1\|UniProtKB=C3VMK9	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000003417.4\|UniProtKB=F6YS83	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000014644.3\|UniProtKB=M3WL24	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000002246.3\|UniProtKB=F7DFE8	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000047841.1\|UniProtKB=A0A6I8NSX1	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010015115.1\|UniProtKB=E1C8Q0	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000014144.1\|UniProtKB=H9GKQ3	Anolis carolinensis	LDO
XENLA\|Gene=cldn2.L\|UniProtKB=A0A1L8F6M6	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-994508\|UniProtKB=A0A803JKT4	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000015354.2\|UniProtKB=H2MKK9	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-040912-26\|UniProtKB=A0A8M2BHN3	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000017486.1\|UniProtKB=W5NLT2	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000001408.2\|UniProtKB=H2L7D2	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000027964.1\|UniProtKB=A0A3B3IEX7	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-050417-293\|UniProtKB=Q561T6	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000017416.1\|UniProtKB=W5NLL2	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000020534.1\|UniProtKB=H2Y1V9	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000023118.1\|UniProtKB=H2XNH4	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000006335.3\|UniProtKB=F6PX91	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000000466.3\|UniProtKB=F6YW52	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000013927.2\|UniProtKB=F6PQC6	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000008241.3\|UniProtKB=F6R4U4	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000021125.1\|UniProtKB=H2XJV5	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000018196.1\|UniProtKB=A0A1W5BNS4	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000009650.3\|UniProtKB=F6WVA9	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000004592.3\|UniProtKB=F6PSB3	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000020956.1\|UniProtKB=H2XV98	Ciona intestinalis	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_77360\|UniProtKB=C3Z150	Branchiostoma floridae	O