PANTHER Gene Information   
Gene Symbol(s): PSMD10
Organism: Canis lupus familiaris
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Gene Name: Proteasome 26S subunit, non-ATPase 10
Gene ID: ENSCAFG00845018812.1
Protein ID: A0A8I3PF76
Persistent Id: PTN002380946
Alternate Ids:
A0A8I3PF76_CANLF(UniProtKB-ID) XM_538135(refSeq)
ENSCAFP00845026053(Ensembl_PRO) 481014(GeneID)
57112311(GI) A0A8I3PF76(Synonym)
ENSCAFG00845018812(Ensembl) ENSCAFT00845033279(Ensembl_TRS)
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PANTHER Classification
PANTHER Family: ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED (PTHR24126)
PANTHER Subfamily: 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 10 (PTHR24126:SF24)  
PANTHER GO-slim Molecular Function: RNA polymerase II-specific DNA-binding transcription factor binding
PANTHER GO-slim Biological Process: regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component: nucleus
PANTHER protein class:
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: RNA polymerase II-specific DNA-binding transcription factor binding, cytoskeletal protein binding, protein-macromolecule adaptor activity, transmembrane transporter binding
GO BP Complete: negative regulation of transcription by RNA polymerase II, positive regulation of cell growth, negative regulation of DNA damage response, signal transduction by p53 class mediator, negative regulation of release of cytochrome c from mitochondria, negative regulation of MAPK cascade, proteasome regulatory particle assembly, positive regulation of protein ubiquitination, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, protein localization to plasma membrane, regulation of transcription by RNA polymerase II
GO CC Complete: nucleus, cytoskeleton, proteasome regulatory particle, base subcomplex, intermediate filament cytoskeleton, cytosol, neuron projection, plasma membrane
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: PCP/CE pathway, Autodegradation of Cdh1 by Cdh1:APC/C, Ub-specific processing proteases, Class I MHC mediated antigen processing & presentation, Antigen processing: Ubiquitination & Proteasome degradation, Degradation of DVL, Assembly of the pre-replicative complex, Regulation of ornithine decarboxylase (ODC), MAPK1/MAPK3 signaling, G2/M Transition, APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint, Cell Cycle, Mitotic, Degradation of AXIN, TNFR2 non-canonical NF-kB pathway, Mitotic G1 phase and G1/S transition, Activation of NF-kappaB in B cells, Interleukin-1 signaling, Regulation of mitotic cell cycle, Mitotic G2-G2/M phases, Transport of small molecules, Innate Immune System, ABC-family proteins mediated transport, DNA Replication, Intracellular signaling by second messengers, Metabolism of RNA, Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins, Nuclear events mediated by NFE2L2, Stabilization of p53, Cdc20:Phospho-APC/C mediated degradation of Cyclin A, FBXL7 down-regulates AURKA during mitotic entry and in early mitosis, NIK-->noncanonical NF-kB signaling, Regulation of RAS by GAPs, Regulation of RUNX2 expression and activity, The role of GTSE1 in G2/M progression after G2 checkpoint, RAF/MAP kinase cascade, CDK-mediated phosphorylation and removal of Cdc6, Cyclin A:Cdk2-associated events at S phase entry, MAPK6/MAPK4 signaling, APC/C:Cdc20 mediated degradation of mitotic proteins, TCF dependent signaling in response to WNT, PTEN Regulation, Generic Transcription Pathway, APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, Degradation of beta-catenin by the destruction complex, Adaptive Immune System, TCR signaling, Beta-catenin independent WNT signaling, Cytokine Signaling in Immune system, RNA Polymerase II Transcription, G2/M Checkpoints, Downstream signaling events of B Cell Receptor (BCR), S Phase, DNA Replication Pre-Initiation, Cell Cycle, MAPK family signaling cascades, Cellular responses to stress, Mitotic Metaphase and Anaphase, Transcriptional regulation by RUNX2, Asymmetric localization of PCP proteins, Signaling by Interleukins, Regulation of mRNA stability by proteins that bind AU-rich elements, Orc1 removal from chromatin, Regulation of PTEN stability and activity, Synthesis of DNA, UCH proteinases, Gene expression (Transcription), Cellular response to hypoxia, Metabolism of amino acids and derivatives, Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha, Hedgehog 'on' state, APC/C:Cdc20 mediated degradation of Securin, Transcriptional regulation by RUNX3, Downstream TCR signaling, Signal Transduction, Separation of Sister Chromatids, Ubiquitin-dependent degradation of Cyclin D, PIP3 activates AKT signaling, GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2, KEAP1-NFE2L2 pathway, Cellular responses to stimuli, p53-Dependent G1/S DNA damage checkpoint, Metabolism of polyamines, Post-translational protein modification, Metabolism, AUF1 (hnRNP D0) binds and destabilizes mRNA, C-type lectin receptors (CLRs), Cell Cycle Checkpoints, Interleukin-1 family signaling, Hedgehog ligand biogenesis, APC/C-mediated degradation of cell cycle proteins, Signaling by the B Cell Receptor (BCR), FCERI mediated NF-kB activation, p53-Independent DNA Damage Response, Mitotic Anaphase, p53-Independent G1/S DNA damage checkpoint, Signaling by WNT, Immune System, Cellular response to chemical stress, G1/S DNA Damage Checkpoints, Degradation of GLI1 by the proteasome, SCF(Skp2)-mediated degradation of p27/p21, Neddylation, Switching of origins to a post-replicative state, GLI3 is processed to GLI3R by the proteasome, Hedgehog 'off' state, M Phase, Metabolism of proteins, Fc epsilon receptor (FCERI) signaling, Dectin-1 mediated noncanonical NF-kB signaling, Autodegradation of the E3 ubiquitin ligase COP1, CLEC7A (Dectin-1) signaling, Signaling by Hedgehog, Antigen processing-Cross presentation, Cross-presentation of soluble exogenous antigens (endosomes), Ubiquitin Mediated Degradation of Phosphorylated Cdc25A, G1/S Transition, Deubiquitination, p53-Dependent G1 DNA Damage Response, Cyclin E associated events during G1/S transition , Regulation of RUNX3 expression and activity

Orthologs