PANTHER Gene Information

Gene Symbol(s):

NOC2L

Organism:

Canis lupus familiaris

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Gene Name:

Nucleolar complex protein 2 homolog

Gene ID:

ENSCAFG00845019446.1

Protein ID:

A0A8I3PGV8

Persistent Id:

PTN000293948

Alternate Ids:

ENSCAFT00845034304(Ensembl_TRS)	A0A8I3PGV8(Synonym)
ENSCAFP00845026852(Ensembl_PRO)	A0A8I3PGV8_CANLF(UniProtKB-ID)
ENSCAFG00845019446(Ensembl)
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PANTHER Classification

PANTHER Family:	NUCLEOLAR COMPLEX 2 AND RAD4-RELATED (PTHR12687)
PANTHER Subfamily:	NUCLEOLAR COMPLEX PROTEIN 2 HOMOLOG (PTHR12687:SF4)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	ribosomal large subunit biogenesis
PANTHER GO-slim Cellular Component:	90S preribosome nuclear protein-containing complex preribosome, large subunit precursor nucleolus nucleoplasm
PANTHER protein class:

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	transcription corepressor activity, histone binding
GO BP Complete:	negative regulation of transcription by RNA polymerase II, ribosomal large subunit biogenesis
GO CC Complete:	nucleus, Noc2p-Noc3p complex, Noc1p-Noc2p complex, nucleolus, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Gene expression (Transcription), Regulation of TP53 Activity, Generic Transcription Pathway, Transcriptional Regulation by TP53, RNA Polymerase II Transcription, Regulation of TP53 Activity through Phosphorylation

Orthologs

ID	Organism	Type
PANTR\|Ensembl=ENSPTRG00000050461.1\|UniProtKB=A0A2I3RXN5	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000025539.2\|UniProtKB=G3RSZ4	Gorilla gorilla gorilla	O
HUMAN\|HGNC=24517\|UniProtKB=Q9Y3T9	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000050965.1\|UniProtKB=A0A2I3SUZ2	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000022530.4\|UniProtKB=H2R0B1	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000007732.3\|UniProtKB=G3QXM0	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000015800.4\|UniProtKB=F7GQM7	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1931051\|UniProtKB=Q9WV70	Mus musculus	LDO
RAT\|RGD=1309387\|UniProtKB=E9PTF3	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000016528\|UniProtKB=Q3SYU1	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000023973.4\|UniProtKB=A0A287A6S6	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000023976.4\|UniProtKB=F6Y6S9	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000003356.6\|UniProtKB=M3W071	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000018641.4\|UniProtKB=A0A5F8GFJ5	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000050178.1\|UniProtKB=A0A6I8NDW9	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010017223.1\|UniProtKB=A0A8V0YTE9	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000008492.4\|UniProtKB=A0A803SRV2	Anolis carolinensis	LDO
XENLA\|Gene=noc2l.S\|UniProtKB=A0A1L8FG38	Xenopus laevis	O
XENLA\|Gene=noc2l.L\|UniProtKB=A0A1L8FM05	Xenopus laevis	LDO
XENTR\|Ensembl=ENSXETG00000031054\|UniProtKB=A0A6I8QE86	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000005561.2\|UniProtKB=H2LLT5	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-000607-75\|UniProtKB=F1QFC4	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000007227.1\|UniProtKB=W5MK47	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000005419.3\|UniProtKB=F6YQR4	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118429961\|UniProtKB=A0A9J7MC81	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC585237\|UniProtKB=A0A7M7P1W3	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00007413\|UniProtKB=O17580	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00025730\|UniProtKB=A8WTM7	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00117849\|UniProtKB=A0A2A6B9I0	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0032925\|UniProtKB=Q9VIF0	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP010536\|UniProtKB=A0A1S4H4A1	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC005421\|UniProtKB=D6WYX1	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_322760\|UniProtKB=E9GWX5	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW011532\|UniProtKB=B7Q746	Ixodes scapularis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g247088\|UniProtKB=A7SSA7	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG57673\|UniProtKB=B3S038	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_37390\|UniProtKB=A9V1E9	Monosiga brevicollis	LDO
YEAST\|SGD=S000005732\|UniProtKB=P39744	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_ADL277W\|UniProtKB=Q75B54	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000192871\|UniProtKB=Q59M49	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_D12012g\|UniProtKB=Q6C9D7	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_00946\|UniProtKB=Q5BET4	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_1G16330\|UniProtKB=Q4WRH1	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU02066\|UniProtKB=Q7SEZ7	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_06141\|UniProtKB=A7ELE4	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_11393\|UniProtKB=Q0UA21	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPAC1B3.09c\|UniProtKB=O13874	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_04346\|UniProtKB=B6K6L1	Schizosaccharomyces japonicus	O
SCHPO\|PomBase=SPAC1142.04\|UniProtKB=Q9P7G0	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_01494\|UniProtKB=B6JY35	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNH01320\|UniProtKB=Q5KCK3	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_02343\|UniProtKB=A0A0D1C8Q3	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_07342\|UniProtKB=E3K9I2	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_07347\|UniProtKB=E3K9I7	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_07339\|UniProtKB=E3K9H9	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_9693\|UniProtKB=F4NWW3	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_105790\|UniProtKB=C4M9H6	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0284383\|UniProtKB=Q54PQ6	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_29382\|UniProtKB=F0ZDI7	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_18_1610\|UniProtKB=Q4QDM8	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb10.389.1290\|UniProtKB=Q389A0	Trypanosoma brucei	LDO
GIAIC\|EnsemblGenome=GL50803_10675\|UniProtKB=A8B951	Giardia intestinalis	LDO
TRIV3\|Gene_ORFName=TVAG_062280\|UniProtKB=A2G421	Trichomonas vaginalis	LDO
PLAF7\|EnsemblGenome=PF3D7_1340300\|UniProtKB=Q8IDT3	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00005057001\|UniProtKB=A0BP41	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00027165001\|UniProtKB=A0EHP8	Paramecium tetraurelia	LDO
PHYRM\|Gene=H3GK58_PHYRM\|UniProtKB=H3GK58	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_09g391652v5\|UniProtKB=A0A2K3DE77	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00032p00060700\|UniProtKB=U5CNQ8	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_224G00300\|UniProtKB=A0A0K9PIT6	Zostera marina	O
MUSAM\|EnsemblGenome=Ma04_g38480\|UniProtKB=A0A804IYJ9	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_006089mg\|UniProtKB=K3XVY1	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3005G028100\|UniProtKB=A0A1B6PPU2	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb093290\|UniProtKB=A0A1D6EIG3	Zea mays	O
ORYSJ\|EnsemblGenome=Os12g0163200\|UniProtKB=Q2QXB4	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_4g01080v3\|UniProtKB=I1IG81	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0423800\|UniProtKB=A0A8I6Y4S3	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS5B02G016900\|UniProtKB=A0A3B6LDK6	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5A02G019600\|UniProtKB=A0A3B6KBN2	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5D02G025000\|UniProtKB=A0A3B6ML42	Triticum aestivum	O
NELNU\|Gene=LOC104589409\|UniProtKB=A0A1U7Z1U0	Nelumbo nucifera	O
SPIOL\|Gene=LOC110804385\|UniProtKB=A0A9R0KBM0	Spinacia oleracea	O
HELAN\|EnsemblGenome=HanXRQr2_Chr12g0529711\|UniProtKB=A0A251SKM1	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C900492800\|UniProtKB=A0A9R1UKD8	Lactuca sativa	O
LACSA\|Gene_ORFName=LSAT_V11C500276360\|UniProtKB=A0A9R1VIA7	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv11b002387mg\|UniProtKB=A0A022RIM1	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a025263mg\|UniProtKB=A0A022Q7T9	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_28061\|UniProtKB=A0A1U8EJX0	Capsicum annuum	O
SOLLC\|EnsemblGenome=Solyc05g023710.3\|UniProtKB=A0A3Q7HBP5	Solanum lycopersicum	O
TOBAC\|Gene=LOC107791930\|UniProtKB=A0A1S3ZYX1	Nicotiana tabacum	O
TOBAC\|Gene=LOC107769426\|UniProtKB=A0A1S3XW78	Nicotiana tabacum	O
EUCGR\|EnsemblGenome=EUGRSUZ_G02808\|UniProtKB=A0A059BHM1	Eucalyptus grandis	O
BRANA\|Gene_ORFName=DARMORV10_C08P30800.1\|UniProtKB=A0A078HTN3	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_A09P48510.1\|UniProtKB=A0A078HSF7	Brassica napus	O
BRACM\|EnsemblGenome=Bra007171\|UniProtKB=M4CSH9	Brassica campestris	O
ARATH\|TAIR=locus=2100006\|UniProtKB=Q0WVH0	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107924520\|UniProtKB=A0A1U8L7B7	Gossypium hirsutum	O
GOSHI\|Gene=LOC107945711\|UniProtKB=A0A1U8NBF0	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_043089\|UniProtKB=A0A061FMK8	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g004881mg\|UniProtKB=A0A067E054	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_008G043400v3\|UniProtKB=A0A2K1ZBL5	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_10G043700\|UniProtKB=A0A251JY74	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_0714470\|UniProtKB=B9SUP6	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_05G088900\|UniProtKB=A0A0R0JST2	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_17G186500\|UniProtKB=K7MMG2	Glycine max	O
MEDTR\|EnsemblGenome=MTR_6g033410\|UniProtKB=A0A072UIM4	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr07_35180\|UniProtKB=A0A2I4FAZ3	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_3G215640\|UniProtKB=A0A0A0LC17	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_2G217500\|UniProtKB=A0A251QKP8	Prunus persica	O
AMBTC\|EnsemblGenome=AMTR_s00020p00038010\|UniProtKB=W1PVT5	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_38G01160\|UniProtKB=A0A0K9P4S3	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma03_g07360\|UniProtKB=A0A804I9G6	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_034436mg\|UniProtKB=K4A6D2	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3001G206500\|UniProtKB=A0A1B6QK03	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb220970\|UniProtKB=A0A1D6GNQ2	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os10g0495500\|UniProtKB=Q8LNU5	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_3g29890v3\|UniProtKB=I1I527	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.1HG0045870\|UniProtKB=A0A8I7B0X2	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS1B02G180700\|UniProtKB=A0A3B5YVT9	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1A02G163900\|UniProtKB=A0A3B5XYN1	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1D02G160800\|UniProtKB=A0A3B5ZU92	Triticum aestivum	LDO
NELNU\|Gene_ORFName=HUJ06_011590\|UniProtKB=A0A1U8B627	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110777413\|UniProtKB=A0A9R0HVP8	Spinacia oleracea	O
SPIOL\|Gene=LOC110794331\|UniProtKB=A0A9R0IU18	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr02g0083021\|UniProtKB=A0A251VIF1	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C600317630\|UniProtKB=A0A9R1V8A4	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a003490mg\|UniProtKB=A0A022S1X0	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_06030\|UniProtKB=A0A1U8FV05	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400017744\|UniProtKB=M1BI66	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc02g081680.3\|UniProtKB=A0A3Q7F7R9	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107790269\|UniProtKB=A0A1S3ZTG8	Nicotiana tabacum	O
TOBAC\|Gene=LOC107772222\|UniProtKB=A0A1S3Y4P1	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi06g01107\|UniProtKB=D7T1D9	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_B03642\|UniProtKB=A0A059D9M6	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=GSBRNA2T00013281001\|UniProtKB=A0A078G338	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_C07P04660.1\|UniProtKB=A0A078GKN9	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00083701001\|UniProtKB=A0A078I878	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra039628\|UniProtKB=M4FEV6	Brassica campestris	LDO
ARATH\|TAIR=locus=2062205\|UniProtKB=Q9ZPV5	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107893771\|UniProtKB=A0A1U8IEV0	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_026791\|UniProtKB=A0A061F4X7	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g004625mg\|UniProtKB=A0A067EMM8	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_001G012800v3\|UniProtKB=A0A2K2BQQ5	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_17G118000\|UniProtKB=A0A2C9U838	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0852470\|UniProtKB=B9RUF4	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_15G039500\|UniProtKB=K7M9F8	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_13G335000\|UniProtKB=A0A0R0GXK5	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_1g110560\|UniProtKB=G7ID95	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr05_15790\|UniProtKB=A0A2I4F0X7	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_2G406730\|UniProtKB=A0A0A0LMM1	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_6G014700\|UniProtKB=A0A251NIM5	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_108187\|UniProtKB=D8S433	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_144099\|UniProtKB=D8R4W0	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c24_4150\|UniProtKB=A0A2K1IFF0	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0061s0134\|UniProtKB=A0A2R6WSV9	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_001060260\|UniProtKB=A0A1Y1HVV1	Klebsormidium nitens	LDO