PANTHER Gene Information   
Gene Symbol(s): CDC20
Organism: Canis lupus familiaris
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Gene Name: Cell division cycle 20
Gene ID: ENSCAFG00845019556.1
Protein ID: A0A8I3NZ86
Persistent Id: PTN000460232
Alternate Ids:
100855774(GeneID) ENSCAFP00845027044(Ensembl_PRO)
A0A8I3NZ86_CANLF(UniProtKB-ID) XP_003639578(refSeq)
ENSCAFG00845019556(Ensembl) 359321384(GI)
ENSCAFT00845034522(Ensembl_TRS) A0A8I3NZ86(Synonym)
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PANTHER Classification
PANTHER Family: CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED (PTHR19918)
PANTHER Subfamily: CELL DIVISION CYCLE PROTEIN 20 HOMOLOG (PTHR19918:SF3)  
PANTHER GO-slim Molecular Function: enzyme activator activity
protein-containing complex binding
PANTHER GO-slim Biological Process: anaphase-promoting complex-dependent catabolic process
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
PANTHER GO-slim Cellular Component: anaphase-promoting complex
PANTHER protein class: ubiquitin-protein ligase
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: ubiquitin-like ligase-substrate adaptor activity, ubiquitin ligase activator activity, anaphase-promoting complex binding
GO BP Complete: positive regulation of synapse maturation, positive regulation of anaphase-promoting complex-dependent catabolic process, mitotic sister chromatid cohesion, positive regulation of synaptic plasticity, regulation of meiotic nuclear division, anaphase-promoting complex-dependent catabolic process, positive regulation of mitotic metaphase/anaphase transition, metaphase/anaphase transition of meiosis I, mitotic spindle assembly
GO CC Complete: centrosome, anaphase-promoting complex, cytosol, mitotic checkpoint complex, kinetochore, nucleoplasm
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Mitotic Metaphase and Anaphase, Cdc20:Phospho-APC/C mediated degradation of Cyclin A, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, APC/C-mediated degradation of cell cycle proteins, Mitotic Spindle Checkpoint, Mitotic Anaphase, Ub-specific processing proteases, Signaling by Rho GTPases, Inactivation of APC/C via direct inhibition of the APC/C complex, Immune System, Class I MHC mediated antigen processing & presentation, Antigen processing: Ubiquitination & Proteasome degradation, Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase, Regulation of APC/C activators between G1/S and early anaphase, APC/C:Cdc20 mediated degradation of Cyclin B, APC/C:Cdc20 mediated degradation of mitotic proteins, M Phase, Resolution of Sister Chromatid Cohesion, APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint, Cell Cycle, Mitotic, EML4 and NUDC in mitotic spindle formation, Metabolism of proteins, SCF-beta-TrCP mediated degradation of Emi1, APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, Regulation of mitotic cell cycle, APC/C:Cdc20 mediated degradation of Securin, Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components, Amplification of signal from the kinetochores, Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal, Adaptive Immune System, Separation of Sister Chromatids, Signal Transduction, RHO GTPase Effectors, Phosphorylation of Emi1, APC-Cdc20 mediated degradation of Nek2A, Post-translational protein modification, Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins, Deubiquitination, Mitotic Prometaphase, Cell Cycle, RHO GTPases Activate Formins, Cell Cycle Checkpoints

Orthologs