PANTHER Gene Information   
Gene Symbol(s): PARP2
Organism: Canis lupus familiaris
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Gene Name: Poly [ADP-ribose] polymerase
Gene ID: ENSCAFG00845021742.1
Protein ID: A0A8I3P8W2
Persistent Id: PTN008945621
Alternate Ids:
A0A8I3P8W2(Synonym) ENSCAFG00845021742(Ensembl)
ENSCAFP00845030058(Ensembl_PRO) A0A8I3P8W2_CANLF(UniProtKB-ID)
ENSCAFT00845038390(Ensembl_TRS)
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PANTHER Classification
PANTHER Family: DNA LIGASE (PTHR10459)
PANTHER Subfamily: POLY [ADP-RIBOSE] POLYMERASE 2 (PTHR10459:SF60)  
PANTHER GO-slim Molecular Function: catalytic activity, acting on a protein
pentosyltransferase activity
PANTHER GO-slim Biological Process: double-strand break repair
post-translational protein modification
PANTHER GO-slim Cellular Component: nucleolus
PANTHER protein class: DNA metabolism protein
Pathway Categories: FAS signaling pathway
   Poly(ADP-ribose) polymerase
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: poly-ADP-D-ribose binding, nucleotidyltransferase activity, NAD DNA ADP-ribosyltransferase activity, NAD+-protein-serine ADP-ribosyltransferase activity, NAD+-protein-aspartate ADP-ribosyltransferase activity, nucleosome binding, NAD+-protein ADP-ribosyltransferase activity, NAD+-protein-glutamate ADP-ribosyltransferase activity, damaged DNA binding, NAD+-protein poly-ADP-ribosyltransferase activity, poly-ADP-D-ribose modification-dependent protein binding
GO BP Complete: base-excision repair, DNA ADP-ribosylation, extrinsic apoptotic signaling pathway, DNA repair-dependent chromatin remodeling, decidualization, protein poly-ADP-ribosylation, protein auto-ADP-ribosylation, double-strand break repair
GO CC Complete: site of DNA damage, nucleolus, nucleoplasm
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: HDR through MMEJ (alt-NHEJ), Formation of Incision Complex in GG-NER, DNA Damage Recognition in GG-NER, Global Genome Nucleotide Excision Repair (GG-NER), Nucleotide Excision Repair, Base Excision Repair, DNA Double-Strand Break Repair, DNA Repair, Dual Incision in GG-NER, Resolution of Abasic Sites (AP sites), Homology Directed Repair, Resolution of AP sites via the multiple-nucleotide patch replacement pathway, POLB-Dependent Long Patch Base Excision Repair

Orthologs