PANTHER Gene Information

Gene Symbol(s):

SLC6A8

Organism:

Canis lupus familiaris

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Gene Name:

Transporter

Gene ID:

ENSCAFG00845023957.1

Protein ID:

A0A8I3S431

Persistent Id:

PTN008975170

Alternate Ids:

ENSCAFP00845033211(Ensembl_PRO)	ENSCAFT00845042363(Ensembl_TRS)
ENSCAFG00845023957(Ensembl)	A0A8I3S431_CANLF(UniProtKB-ID)
A0A8I3S431(Synonym)
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PANTHER Classification

PANTHER Family:	SODIUM/CHLORIDE DEPENDENT TRANSPORTER (PTHR11616)
PANTHER Subfamily:	SODIUM- AND CHLORIDE-DEPENDENT CREATINE TRANSPORTER 1 (PTHR11616:SF96)
PANTHER GO-slim Molecular Function:	chloride transmembrane transporter activity amino acid:sodium symporter activity secondary active monocarboxylate transmembrane transporter activity
PANTHER GO-slim Biological Process:	amino acid transport sodium ion transmembrane transport
PANTHER GO-slim Cellular Component:	plasma membrane
PANTHER protein class:	primary active transporter

Pathway Categories:

Nicotinic acetylcholine receptor signaling pathway

high affinity choline transporter

Muscarinic acetylcholine receptor 2 and 4 signaling pathway

high affinity choline transporter

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	creatine:sodium symporter activity, metal ion binding, gamma-aminobutyric acid:sodium:chloride symporter activity
GO BP Complete:	sodium ion transport, neurotransmitter transport, creatine transmembrane transport, sodium ion transmembrane transport, amino acid transport
GO CC Complete:	plasma membrane, apical plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Metabolism of amino acids and derivatives, Metabolism, Creatine metabolism

Orthologs

ID	Organism	Type
HUMAN\|HGNC=11055\|UniProtKB=P48029	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000044981.1\|UniProtKB=A0A2I3T8I5	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000050829.1\|UniProtKB=K7DP91	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000034957.2\|UniProtKB=G3QQL1	Gorilla gorilla gorilla	O
GORGO\|Ensembl=ENSGGOG00000004977.3\|UniProtKB=G3SKP7	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000012742.4\|UniProtKB=F7ET12	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2147834\|UniProtKB=Q8VBW1	Mus musculus	LDO
RAT\|RGD=619711\|UniProtKB=P28570	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000009959\|UniProtKB=O18875	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000012771.5\|UniProtKB=A0A480PP25	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000013965.3\|UniProtKB=A0A3Q2H951	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000004036.6\|UniProtKB=M3W1G1	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000008271.5\|UniProtKB=F6Z838	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000010213.3\|UniProtKB=F6RNY8	Ornithorhynchus anatinus	LDO
ANOCA\|Ensembl=ENSACAG00000008691.2\|UniProtKB=A0A803TBD2	Anolis carolinensis	LDO
XENLA\|Gene=slc6a8.S\|UniProtKB=A0A1L8F1J9	Xenopus laevis	O
XENLA\|Gene=slc6a8.L\|UniProtKB=A0A8J1LJ85	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-986840\|UniProtKB=A0A6I8QAW0	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000018600.2\|UniProtKB=H2MWL6	Oryzias latipes	LDO
DANRE\|Gene=slc6a8\|UniProtKB=A0A8M1P953	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000014590.1\|UniProtKB=W5NBF5	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000006122.3\|UniProtKB=F6VSC2	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118415466\|UniProtKB=A0A9J7L4L6	Branchiostoma floridae	O
BRAFL\|Gene=LOC118415465\|UniProtKB=A0A9J7L4V2	Branchiostoma floridae	O
BRAFL\|Gene=LOC118415467\|UniProtKB=A0A9J7L5Y6	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC115919833\|UniProtKB=A0A7M7N4X0	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC592574\|UniProtKB=A0A7M7HMQ1	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115926076\|UniProtKB=A0A7M7T161	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC757159\|UniProtKB=A0A7M7N2B0	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100888394\|UniProtKB=A0A7M7N3R5	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC575802\|UniProtKB=A0A7M7N1D2	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC592669\|UniProtKB=A0A7M7N237	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115926051\|UniProtKB=A0A7M7P6P4	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC764578\|UniProtKB=A0A7M7MX21	Strongylocentrotus purpuratus	LDO
IXOSC\|EnsemblGenome=ISCW010973\|UniProtKB=B7Q9C6	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW020974\|UniProtKB=B7Q8Z6	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW016408\|UniProtKB=B7P1X3	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW010971\|UniProtKB=B7Q9C4	Ixodes scapularis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g247614\|UniProtKB=A7SVA2	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG54650\|UniProtKB=B3RSM1	Trichoplax adhaerens	O
EMENI\|EnsemblGenome=ANIA_08966\|UniProtKB=C8VL87	Emericella nidulans	O
PHANO\|EnsemblGenome=SNOG_05834\|UniProtKB=Q0UQY0	Phaeosphaeria nodorum	O
PHANO\|EnsemblGenome=SNOG_04273\|UniProtKB=Q0UVE1	Phaeosphaeria nodorum	O
PLAF7\|EnsemblGenome=PF3D7_0209600\|UniProtKB=O96181	Plasmodium falciparum	O
PLAF7\|EnsemblGenome=PF3D7_1132500\|UniProtKB=Q8II40	Plasmodium falciparum	O
PARTE\|EnsemblGenome=GSPATT00003373001\|UniProtKB=A0DZD7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00003369001\|UniProtKB=A0DZD3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00005033001\|UniProtKB=A0BJE3	Paramecium tetraurelia	O
THEKO\|EnsemblGenome=TK1432\|UniProtKB=Q5JDK2	Thermococcus kodakaraensis	O
LEPIN\|EnsemblGenome=LA_1877\|UniProtKB=Q8F511	Leptospira interrogans	O
AQUAE\|EnsemblGenome=aq_2077\|UniProtKB=O67854	Aquifex aeolicus	O
THEYD\|EnsemblGenome=THEYE_A0808\|UniProtKB=B5YK84	Thermodesulfovibrio yellowstonii	O