PANTHER Gene Information

Gene Symbol(s):

PI4KA

Organism:

Canis lupus familiaris

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Gene Name:

1-phosphatidylinositol 4-kinase

Gene ID:

ENSCAFG00845025057.1

Protein ID:

A0A8I3S947

Persistent Id:

PTN000006049

Alternate Ids:

ENSCAFP00845034705(Ensembl_PRO)	A0A8I3S947_CANLF(UniProtKB-ID)
A0A8I3S947(Synonym)	ENSCAFT00845044288(Ensembl_TRS)
ENSCAFG00845025057(Ensembl)
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PANTHER Classification

PANTHER Family:	PHOSPHATIDYLINOSITOL KINASE (PTHR10048)
PANTHER Subfamily:	PHOSPHATIDYLINOSITOL 4-KINASE ALPHA (PTHR10048:SF15)
PANTHER GO-slim Molecular Function:	phosphotransferase activity, alcohol group as acceptor lipid kinase activity
PANTHER GO-slim Biological Process:	intracellular signal transduction phosphatidylinositol phosphate biosynthetic process
PANTHER GO-slim Cellular Component:	plasma membrane cytoplasm
PANTHER protein class:	kinase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	1-phosphatidylinositol 4-kinase activity
GO BP Complete:	phosphatidylinositol-mediated signaling, phosphatidylinositol phosphate biosynthetic process, phosphorylation, reorganization of cellular membranes to establish viral sites of replication, modulation by host of viral process
GO CC Complete:	cytoplasm, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Synthesis of PIPs at the Golgi membrane, Metabolism, PI Metabolism, Phospholipid metabolism, Synthesis of PIPs at the ER membrane, Metabolism of lipids

Orthologs

ID	Organism	Type
HUMAN\|HGNC=8983\|UniProtKB=P42356	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000014090.5\|UniProtKB=A0A2I3RR13	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000015922.3\|UniProtKB=G3RIN0	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000022167.4\|UniProtKB=F6XII4	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2448506\|UniProtKB=E9Q3L2	Mus musculus	LDO
RAT\|RGD=621213\|UniProtKB=O08662	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000013971.6\|UniProtKB=A0A140T888	Bos taurus	LDO
BOVIN\|Gene=PI4KA\|UniProtKB=O02811	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000010092.5\|UniProtKB=A0A286ZXT3	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000023152.4\|UniProtKB=A0A3Q2H786	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000006001.6\|UniProtKB=A0A5F5XNT1	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000017648.4\|UniProtKB=A0A5F8HBG3	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000040206.1\|UniProtKB=A0A6I8N2Z2	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010024198.1\|UniProtKB=A0A8V0ZYM1	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000001761.4\|UniProtKB=A0A803U179	Anolis carolinensis	LDO
XENLA\|Gene=pi4ka.L\|UniProtKB=A0A1L8I0J8	Xenopus laevis	O
XENLA\|Gene=pi4ka.S\|UniProtKB=A0A8J0PZ67	Xenopus laevis	LDO
XENTR\|Gene=pi4ka\|UniProtKB=A0A8J1JYW7	Xenopus tropicalis	LDO
DANRE\|Gene=pi4kaa\|UniProtKB=A0A8M3AWF4	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000002180.1\|UniProtKB=W5M2N3	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000002430.3\|UniProtKB=F6QH36	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118409646\|UniProtKB=A0A9J7MGQ8	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC105445366\|UniProtKB=A0A7M7P8N5	Strongylocentrotus purpuratus	LDO
STRPU\|EnsemblGenome=LOC590935\|UniProtKB=A0A7M7T1Q4	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00013557\|UniProtKB=Q9XW63	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG03566\|UniProtKB=A8WVC8	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00104936\|UniProtKB=A0A2A6BBK7	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0267350\|UniProtKB=M9PDM4	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP010801\|UniProtKB=Q7Q237	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC014935\|UniProtKB=D2A3W3	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_324239\|UniProtKB=E9H135	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW020487\|UniProtKB=B7PXE6	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW015061\|UniProtKB=B7QKB8	Ixodes scapularis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g165173\|UniProtKB=A7S165	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG55997\|UniProtKB=B3RTP4	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_169\|UniProtKB=A9UNX9	Monosiga brevicollis	LDO
YEAST\|SGD=S000004296\|UniProtKB=P37297	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_ADL033W\|UniProtKB=Q75AF0	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000198621\|UniProtKB=A0A1D8PTE0	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_E28153g\|UniProtKB=Q6C4B9	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_04278\|UniProtKB=Q5B5A2	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_7G03760\|UniProtKB=Q4WG47	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU09367\|UniProtKB=Q7SCR6	Neurospora crassa	LDO
SCLS1\|Gene_ORFName=SS1G_12900\|UniProtKB=A7F5M2	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_03928\|UniProtKB=Q0UWD6	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPBC577.06c\|UniProtKB=Q9USR3	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_04537\|UniProtKB=B6K734	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNI02140\|UniProtKB=Q5KBL4	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_06103\|UniProtKB=A0A0D1DPV0	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_08672\|UniProtKB=E3KGR1	Puccinia graminis	LDO
ENTH1\|EnsemblGenome=EHI_073560\|UniProtKB=C4LXL6	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_148700\|UniProtKB=C4LT40	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0277537\|UniProtKB=Q54ZN9	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_158137\|UniProtKB=F1A0X4	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_29_1450\|UniProtKB=E9AE04	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb927.3.4020\|UniProtKB=Q57WD8	Trypanosoma brucei	LDO
PARTE\|EnsemblGenome=GSPATT00029485001\|UniProtKB=A0BJY8	Paramecium tetraurelia	LDO
CHLRE\|EnsemblGenome=CHLRE_05g245550v5\|UniProtKB=A0A2K3DS70	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00064p00131270\|UniProtKB=U5DED0	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_58G00520\|UniProtKB=A0A0K9NV21	Zostera marina	O
ZOSMR\|Gene_ORFName=ZOSMA_133G00710\|UniProtKB=A0A0K9Q147	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma01_g15820\|UniProtKB=A0A804HUK4	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_0338542mg\|UniProtKB=A0A0Q3MYA9	Setaria italica	LDO
SETIT\|EnsemblGenome=SETIT_0338541mg\|UniProtKB=A0A0Q3MY94	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3001G118000\|UniProtKB=A0A1B6QIL1	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb216400\|UniProtKB=A0A1D6GJB6	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os03g0711200\|UniProtKB=A0A0P0W249	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_1g11317v3\|UniProtKB=I1GP69	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.4HG0337080\|UniProtKB=A0A8I6WYA3	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS4D02G046100\|UniProtKB=A0A3B6JFX8	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4A02G268300\|UniProtKB=A0A3B6HW75	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4B02G045900\|UniProtKB=A0A3B6IMT1	Triticum aestivum	LDO
NELNU\|Gene=LOC104608021\|UniProtKB=A0A1U8B858	Nelumbo nucifera	O
NELNU\|Gene=LOC104596308\|UniProtKB=A0A1U7ZNJ4	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110799265\|UniProtKB=A0A9R0K7E3	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr10g0453321\|UniProtKB=A0A251TQC8	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C500271350\|UniProtKB=A0A9R1X9G7	Lactuca sativa	O
HELAN\|EnsemblGenome=HanXRQr2_Chr03g0110121\|UniProtKB=A0A251U4P7	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C900499770\|UniProtKB=A0A9R1UJN3	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a000057mg\|UniProtKB=A0A022RDG0	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_31207\|UniProtKB=A0A2G2YAK2	Capsicum annuum	LDO
SOLLC\|EnsemblGenome=Solyc11g043120.2\|UniProtKB=A0A3Q7IWX2	Solanum lycopersicum	LDO
VITVI\|EnsemblGenome=Vitvi03g00358\|UniProtKB=F6HQK6	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_G00451\|UniProtKB=A0A059B9G3	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=GSBRNA2T00091913001\|UniProtKB=A0A078IHI5	Brassica napus	O
BRACM\|EnsemblGenome=Bra018786\|UniProtKB=M4DQJ3	Brassica campestris	O
BRANA\|Gene_ORFName=GSBRNA2T00029154001\|UniProtKB=A0A078GJ32	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00058899001\|UniProtKB=A0A078HFJ6	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00021163001\|UniProtKB=A0A078GCN1	Brassica napus	O
BRACM\|EnsemblGenome=Bra018885\|UniProtKB=M4DQU2	Brassica campestris	O
BRANA\|Gene_ORFName=GSBRNA2T00042390001\|UniProtKB=A0A078JFU8	Brassica napus	LDO
BRANA\|Gene_ORFName=GSBRNA2T00042922001\|UniProtKB=A0A078GXL5	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra032281\|UniProtKB=M4ETZ9	Brassica campestris	LDO
ARATH\|TAIR=locus=2010202\|UniProtKB=Q9SXA1	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107886983\|UniProtKB=A0A1U8HKK2	Gossypium hirsutum	O
GOSHI\|Gene=LOC107940998\|UniProtKB=A0A1U8MWT5	Gossypium hirsutum	O
GOSHI\|Gene=LOC107945169\|UniProtKB=A0A1U8N606	Gossypium hirsutum	LDO
GOSHI\|Gene=LOC107898766\|UniProtKB=A0A1U8ITP9	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_007300\|UniProtKB=A0A061E1R9	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g000157mg\|UniProtKB=A0A067DTR9	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_004G152400v3\|UniProtKB=B9H0N9	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_009G113700v3\|UniProtKB=B9HRQ6	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_15G165000\|UniProtKB=A0A2C9UGU1	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0937410\|UniProtKB=B9RZB3	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_06G013800\|UniProtKB=I1K784	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_04G013900\|UniProtKB=I1JSQ3	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_3g116250\|UniProtKB=G7J6H9	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr16_18180\|UniProtKB=A0A2I4FZ62	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_7G258840\|UniProtKB=A0A0A0K499	Cucumis sativus	LDO
CUCSA\|EnsemblGenome=Csa_2G245420\|UniProtKB=A0A0A0LIX8	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_8G100100\|UniProtKB=M5VYU6	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_92319\|UniProtKB=D8RG87	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_181608\|UniProtKB=D8SPN5	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c5_19540\|UniProtKB=A0A2K1KKB7	Physcomitrella patens	LDO
PHYPA\|EnsemblGenome=Pp3c22_1940\|UniProtKB=A0A2K1ILX3	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0001s0228\|UniProtKB=A0A2R6XVT0	Marchantia polymorpha	LDO
MARPO\|EnsemblGenome=MARPO_0001s0451\|UniProtKB=A0A2R6XWM5	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_003760040\|UniProtKB=A0A1Y1IFC8	Klebsormidium nitens	LDO