PANTHER Gene Information   
Gene Symbol(s): UBE2D3
Organism: Canis lupus familiaris
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Gene Name: Ubiquitin conjugating enzyme E2 D3
Gene ID: ENSCAFG00845026289.1
Protein ID: A0A8I3S5W5
Persistent Id: PTN009079374
Alternate Ids:
ENSCAFP00845036601(Ensembl_PRO) A0A8I3S5W5(Synonym)
ENSCAFG00845026289(Ensembl) A0A8I3S5W5_CANLF(UniProtKB-ID)
ENSCAFT00845046622(Ensembl_TRS)
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PANTHER Classification
PANTHER Family: UBIQUITIN-CONJUGATING ENZYME E2 (PTHR24068)
PANTHER Subfamily: UBIQUITIN-CONJUGATING ENZYME E2 D3 (PTHR24068:SF415)  
PANTHER GO-slim Molecular Function: ubiquitin conjugating enzyme activity
ubiquitin protein ligase binding
PANTHER GO-slim Biological Process: ubiquitin-dependent protein catabolic process
protein polyubiquitination
PANTHER GO-slim Cellular Component: nucleus
ubiquitin ligase complex
PANTHER protein class: ubiquitin-protein ligase
Pathway Categories: Ubiquitin proteasome pathway
   Ubiquitin-conjugating enzyme E2
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: ATP binding, ubiquitin conjugating enzyme activity, transferase activity
GO BP Complete: protein K11-linked ubiquitination, protein K48-linked ubiquitination, ubiquitin-dependent protein catabolic process
GO CC Complete: nucleus
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Downregulation of SMAD2/3:SMAD4 transcriptional activity, Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer, Protein ubiquitination, Signaling by CSF3 (G-CSF), Toll-like Receptor Cascades, Inactivation of CSF3 (G-CSF) signaling, Death Receptor Signaling, Toll Like Receptor 4 (TLR4) Cascade, Immune System, Signaling by TGFB family members, Class I MHC mediated antigen processing & presentation, Antigen processing: Ubiquitination & Proteasome degradation, Neddylation, E3 ubiquitin ligases ubiquitinate target proteins, Gene expression (Transcription), IKK complex recruitment mediated by RIP1, Metabolism of proteins, TRIF(TICAM1)-mediated TLR4 signaling , Cellular response to hypoxia, Generic Transcription Pathway, Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha, Peroxisomal protein import, TNF signaling, Signaling by TGF-beta Receptor Complex, Adaptive Immune System, Innate Immune System, Signal Transduction, Protein localization, Cytokine Signaling in Immune system, Cellular responses to stimuli, RNA Polymerase II Transcription, MyD88-independent TLR4 cascade , Post-translational protein modification, Regulation of TNFR1 signaling, Signaling by BMP, Cellular responses to stress

Orthologs