The mission of the PANTHER knowledgebase is to support biomedical and other research by providing
comprehensive information about the evolution of protein-coding gene families, particularly
protein phylogeny, function and genetic variation impacting that function. Learn more

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Current Release: PANTHER 19.0 | 15,683 family phylogenetic trees | 144 species | News
Whole genome function views

PANTHER Gene Information

Gene Symbol(s):

MVB12A

Organism:

Canis lupus familiaris

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Tree

Gene Name:

Multivesicular body subunit 12A

Gene ID:

ENSCAFG00845027638.1

Protein ID:

A0A8I3Q367

Persistent Id:

PTN009123028

Alternate Ids:

A0A8I3Q367(Synonym)	ENSCAFT00845048737(Ensembl_TRS)
ENSCAFP00845038238(Ensembl_PRO)	ENSCAFG00845027638(Ensembl)
A0A8I3Q367_CANLF(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	MULTIVESICULAR BODY SUBUNIT 12A (PTHR31612)
PANTHER Subfamily:	MULTIVESICULAR BODY SUBUNIT 12A (PTHR31612:SF2)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	cellular catabolic process regulation of epidermal growth factor receptor signaling pathway endosome to lysosome transport endosome transport via multivesicular body sorting pathway macromolecule catabolic process
PANTHER GO-slim Cellular Component:	cytosol ESCRT I complex
PANTHER protein class:

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	SH3 domain binding
GO BP Complete:	receptor catabolic process, virus maturation, protein transport, endosome to lysosome transport via multivesicular body sorting pathway, viral budding, regulation of epidermal growth factor receptor signaling pathway
GO CC Complete:	late endosome membrane, ESCRT I complex, cytosol

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Membrane Trafficking, Endosomal Sorting Complex Required For Transport (ESCRT), Vesicle-mediated transport

Orthologs

ID	Organism	Type
HUMAN\|HGNC=25153\|UniProtKB=Q96EY5	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000010673.6\|UniProtKB=A0A2I3RLL1	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000027234.2\|UniProtKB=G3SFB3	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000005830.3\|UniProtKB=H9ETI6	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1920961\|UniProtKB=Q78HU3	Mus musculus	LDO
RAT\|RGD=735220\|UniProtKB=Q6P777	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000003914\|UniProtKB=Q3T0N1	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000036568.2\|UniProtKB=A0A287AP77	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000010140.4\|UniProtKB=F6PZ21	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000027607.4\|UniProtKB=A0A337SL83	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000004453.3\|UniProtKB=A0A5F8GFZ1	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000014610.3\|UniProtKB=F7EHM1	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010002573.1\|UniProtKB=A0A8V0XG90	Gallus gallus	O
CHICK\|Gene_ORFName=RCJMB04_14j17\|UniProtKB=Q5ZJX7	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000004718.4\|UniProtKB=H9G9E9	Anolis carolinensis	LDO
XENLA\|Gene=mvb12a\|UniProtKB=Q7ZYJ7	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-5895174\|UniProtKB=A9JTN0	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000015039.2\|UniProtKB=H2MJJ2	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040426-1240\|UniProtKB=Q7SXX7	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000006825.1\|UniProtKB=W5MIP0	lepisosteus oculatus	LDO
CAEEL\|WormBase=WBGene00015508\|UniProtKB=Q17687	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00037252\|UniProtKB=A8XRI4	Caenorhabditis briggsae	LDO
DROME\|FlyBase=FBgn0030894\|UniProtKB=Q9VWY7	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP004695\|UniProtKB=Q7Q2L3	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC016197\|UniProtKB=D6X4S1	Tribolium castaneum	LDO
TRIAD\|EnsemblGenome=TriadG53300\|UniProtKB=B3RNV2	Trichoplax adhaerens	LDO