PANTHER Gene Information

Gene Symbol(s):

UBE2W

Organism:

Canis lupus familiaris

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Gene Name:

Ubiquitin conjugating enzyme E2 W

Gene ID:

ENSCAFG00845028719.1

Protein ID:

A0A8I3QHD3

Persistent Id:

PTN001529472

Alternate Ids:

A0A8I3QHD3_CANLF(UniProtKB-ID)	ENSCAFG00845028719(Ensembl)
A0A8I3QHD3(Synonym)	ENSCAFT00845050774(Ensembl_TRS)
ENSCAFP00845039805(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	UBIQUITIN-CONJUGATING ENZYME E2 (PTHR24068)
PANTHER Subfamily:	UBIQUITIN-CONJUGATING ENZYME E2 W (PTHR24068:SF153)
PANTHER GO-slim Molecular Function:	ubiquitin conjugating enzyme activity
PANTHER GO-slim Biological Process:	proteasome-mediated ubiquitin-dependent protein catabolic process protein polyubiquitination
PANTHER GO-slim Cellular Component:	nucleus
PANTHER protein class:	ubiquitin-protein ligase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	ubiquitin protein ligase binding, ubiquitin conjugating enzyme activity
GO BP Complete:	proteasome-mediated ubiquitin-dependent protein catabolic process, protein K11-linked ubiquitination, negative regulation of TORC1 signaling, protein polyubiquitination, protein monoubiquitination, antiviral innate immune response
GO CC Complete:	nucleus

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Adaptive Immune System, Metabolism of proteins, Immune System, Class I MHC mediated antigen processing & presentation, Antigen processing: Ubiquitination & Proteasome degradation, Protein ubiquitination, Post-translational protein modification, Synthesis of active ubiquitin: roles of E1 and E2 enzymes

Orthologs

ID	Organism	Type
HUMAN\|HGNC=25616\|UniProtKB=Q96B02	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000020348.6\|UniProtKB=H2R378	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000007459.3\|UniProtKB=A0A2I2Z7B4	Gorilla gorilla gorilla	LDO
MOUSE\|MGI=MGI=1914049\|UniProtKB=Q8VDW4	Mus musculus	LDO
RAT\|RGD=6503620\|UniProtKB=B5DEI4	Rattus norvegicus	LDO
RAT\|RGD=15005970\|UniProtKB=M0R6B6	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000048843\|UniProtKB=A6H795	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000006177.5\|UniProtKB=A0A287BC59	Sus scrofa	LDO
FELCA\|Ensembl=ENSFCAG00000027854.4\|UniProtKB=M3WYV9	Felis catus	LDO
ORNAN\|Ensembl=ENSOANG00000008597.4\|UniProtKB=A0A6I8NRU2	Ornithorhynchus anatinus	LDO
ORYLA\|Ensembl=ENSORLG00000025733.1\|UniProtKB=A0A3B3HVW3	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-050506-94\|UniProtKB=Q4VBH4	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-050113-1\|UniProtKB=Q1JPX4	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000003697.1\|UniProtKB=W5M7P1	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000002766.3\|UniProtKB=F7AH68	Ciona intestinalis	LDO
BRAFL\|Gene_ORFName=BRAFLDRAFT_115629\|UniProtKB=C3ZNC4	Branchiostoma floridae	LDO
CAEEL\|WormBase=WBGene00006711\|UniProtKB=Q9XWF6	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG19703\|UniProtKB=A8XWI7	Caenorhabditis briggsae	LDO
DROME\|FlyBase=FBgn0033544\|UniProtKB=A1Z8B5	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP005324\|UniProtKB=Q7PIU2	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC002937\|UniProtKB=D6WH24	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_211776\|UniProtKB=E9GIF0	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW019323\|UniProtKB=B7PTB2	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG185420\|UniProtKB=T1FMS9	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g174994\|UniProtKB=A7SW95	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG50463\|UniProtKB=B3S1U8	Trichoplax adhaerens	LDO
CANAL\|CGD=CAL0000192881\|UniProtKB=Q5A5R2	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_F31955g\|UniProtKB=Q6BZP7	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_02413\|UniProtKB=C8VNX4	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_2G13690\|UniProtKB=Q4X0F1	Neosartorya fumigata	LDO
SCLS1\|Gene_ORFName=SS1G_10020\|UniProtKB=A7EXF9	Sclerotinia sclerotiorum	LDO
CRYNJ\|EnsemblGenome=CNE04250\|UniProtKB=Q5KGB0	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_03443\|UniProtKB=A0A0D1C3P4	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_00822\|UniProtKB=E3JTS4	Puccinia graminis	LDO
DICDI\|dictyBase=DDB_G0268938\|UniProtKB=Q55EY8	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_157952\|UniProtKB=F1A0F8	Dictyostelium purpureum	LDO
TRIV3\|Gene_ORFName=TVAG_130740\|UniProtKB=A2FTA9	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_476010\|UniProtKB=A2DA24	Trichomonas vaginalis	O
PLAF7\|EnsemblGenome=PF3D7_1243700\|UniProtKB=Q8I4Z3	Plasmodium falciparum	O
PLAF7\|EnsemblGenome=PF3D7_1345500\|UniProtKB=Q8IDP1	Plasmodium falciparum	O
PLAF7\|EnsemblGenome=PF3D7_1412900.1\|UniProtKB=Q8ILW5	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00034321001\|UniProtKB=A0C227	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00032900001\|UniProtKB=A0BWY1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00030369001\|UniProtKB=A0BMG6	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00016175001\|UniProtKB=A0DE66	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_36045\|UniProtKB=B8C7B4	Thalassiosira pseudonana	LDO
CHLRE\|EnsemblGenome=CHLRE_02g141450v5\|UniProtKB=A0A2K3E455	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00002p00234950\|UniProtKB=W1NUB1	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_218G00070\|UniProtKB=A0A0K9PJQ8	Zostera marina	O
ZOSMR\|Gene_ORFName=ZOSMA_392G00010\|UniProtKB=A0A0K9P4E5	Zostera marina	O
ZOSMR\|Gene_ORFName=ZOSMA_4G00430\|UniProtKB=A0A0K9NYI4	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma09_g25940\|UniProtKB=A0A804KNS2	Musa acuminata subsp. malaccensis	LDO
MUSAM\|EnsemblGenome=Ma06_g31510\|UniProtKB=A0A804JMI6	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma09_g10400\|UniProtKB=A0A804KI34	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma04_g27600\|UniProtKB=A0A804IUL1	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_023498mg\|UniProtKB=K3ZAC7	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3008G189300\|UniProtKB=C5YT12	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb134110\|UniProtKB=B4FMX0	Zea mays	O
ORYSJ\|EnsemblGenome=Os12g0636800\|UniProtKB=Q2QLM1	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_4g00660v3\|UniProtKB=A0A0Q3HBZ6	Brachypodium distachyon	O
WHEAT\|EnsemblGenome=TraesCS5A02G006200\|UniProtKB=W5G1C0	Triticum aestivum	O
SETIT\|EnsemblGenome=SETIT_040733mg\|UniProtKB=K4AP85	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3001G136900\|UniProtKB=C5WPM7	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb217340\|UniProtKB=A0A804P934	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os03g0681400\|UniProtKB=Q9AYE3	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_1g12480v3\|UniProtKB=I1GPK6	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.4HG0334410\|UniProtKB=F2DS45	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS4A02G288800\|UniProtKB=A0A3B6HXE4	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS4B02G026000\|UniProtKB=A0A3B6IN27	Triticum aestivum	LDO
NELNU\|Gene=LOC104595596\|UniProtKB=A0A1U8A0V0	Nelumbo nucifera	LDO
POPTR\|EnsemblGenome=POPTR_002G030800v3\|UniProtKB=A9PC20	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_005G232100v3\|UniProtKB=A9PH82	Populus trichocarpa	LDO
NELNU\|Gene=LOC104610559\|UniProtKB=A0A1U8B3W1	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110798889\|UniProtKB=A0A9R0K6R4	Spinacia oleracea	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a015306mg\|UniProtKB=A0A022QZ73	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_13305\|UniProtKB=A0A1U8GBI5	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400003753\|UniProtKB=M0ZWM9	Solanum tuberosum	O
TOBAC\|Gene=LOC107776491\|UniProtKB=A0A1S3YHZ6	Nicotiana tabacum	O
TOBAC\|Gene=LOC107769767\|UniProtKB=A0A1S3XX43	Nicotiana tabacum	O
CAPAN\|EnsemblGenome=T459_06395\|UniProtKB=A0A1U8FW96	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400003613\|UniProtKB=M0ZVZ8	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc02g084760.3\|UniProtKB=K4BAZ1	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107824880\|UniProtKB=A0A1S4D1H7	Nicotiana tabacum	LDO
TOBAC\|Gene=LOC107824081\|UniProtKB=A0A1S4CYR5	Nicotiana tabacum	O
TOBAC\|Gene=LOC107759180\|UniProtKB=A0A1S3WXX8	Nicotiana tabacum	LDO
VITVI\|Gene_OrderedLocusName=VIT_18s0001g13180\|UniProtKB=A5AEM8	Vitis vinifera	LDO
BRANA\|Gene_ORFName=GSBRNA2T00027606001\|UniProtKB=A0A078J250	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00043866001\|UniProtKB=A0A078JE31	Brassica napus	O
BRACM\|EnsemblGenome=Bra017759\|UniProtKB=M4DMM4	Brassica campestris	O
BRACM\|EnsemblGenome=Bra011680\|UniProtKB=A0A398AHL5	Brassica campestris	O
ARATH\|TAIR=locus=2115425\|UniProtKB=O23239	Arabidopsis thaliana	O
BRANA\|Gene_ORFName=DARMORV10_A07P41000.1\|UniProtKB=A0A078IBN6	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra015843\|UniProtKB=M4DH66	Brassica campestris	LDO
ARATH\|TAIR=locus=2018447\|UniProtKB=Q9FWT2	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107957952\|UniProtKB=A6MUS6	Gossypium hirsutum	O
GOSHI\|Gene=LOC107905467\|UniProtKB=A0A1U8JBD2	Gossypium hirsutum	LDO
GOSHI\|Gene=LOC107918005\|UniProtKB=A0A1U8KKB9	Gossypium hirsutum	O
GOSHI\|Gene=LOC107934253\|UniProtKB=A0A1U8M5M3	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_034118\|UniProtKB=A0A061FDS1	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g031319mg\|UniProtKB=A0A067H1C2	Citrus sinensis	LDO
RICCO\|Gene_ORFName=RCOM_1595790\|UniProtKB=B9R805	Ricinus communis	LDO
PRUPE\|EnsemblGenome=PRUPE_1G373500\|UniProtKB=M5XFV3	Prunus persica	LDO
PRUPE\|EnsemblGenome=PRUPE_7G162600\|UniProtKB=M5VX01	Prunus persica	LDO
SPIOL\|Gene=LOC110790575\|UniProtKB=A0A9R0IKQ5	Spinacia oleracea	O
HELAN\|EnsemblGenome=HanXRQr2_Chr09g0406941\|UniProtKB=A0A251TZN8	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C400202900\|UniProtKB=A0A9R1VT81	Lactuca sativa	O
HELAN\|Gene_ORFName=HanXRQr2_Chr14g0642941\|UniProtKB=A0A9K3H8E2	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr11g0471341\|UniProtKB=A0A251T8A8	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C200078200\|UniProtKB=A0A9R1W7V7	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a015314mg\|UniProtKB=A0A022R8Q4	Erythranthe guttata	O
TOBAC\|Gene=LOC107796639\|UniProtKB=A0A1S4AE14	Nicotiana tabacum	O
TOBAC\|Gene=LOC107799066\|UniProtKB=A0A1S4AMG6	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi04g02133\|UniProtKB=D7SP59	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_I02390\|UniProtKB=A0A059ARU5	Eucalyptus grandis	O
BRANA\|Gene_ORFName=DARMORV10_C06P01140.1\|UniProtKB=A0A078FHZ3	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00088571001\|UniProtKB=A0A078IDG6	Brassica napus	O
BRACM\|EnsemblGenome=Bra036332\|UniProtKB=M4F5H6	Brassica campestris	O
BRANA\|Gene_ORFName=GSBRNA2T00032965001\|UniProtKB=A0A078GM22	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00077380001\|UniProtKB=A0A078HZ19	Brassica napus	O
BRACM\|EnsemblGenome=Bra032210\|UniProtKB=M4ETS8	Brassica campestris	O
ARATH\|TAIR=locus=2028255\|UniProtKB=P42743	Arabidopsis thaliana	O
BRANA\|Gene_ORFName=GSBRNA2T00076903001\|UniProtKB=A0A078I3B7	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00053183001\|UniProtKB=A0A078H642	Brassica napus	O
BRACM\|EnsemblGenome=Bra027470\|UniProtKB=M4EFA8	Brassica campestris	O
ARATH\|TAIR=locus=2159981\|UniProtKB=Q9FMM0	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107935354\|UniProtKB=A0A1U8MCZ3	Gossypium hirsutum	O
GOSHI\|Gene=LOC107936522\|UniProtKB=A0A1U8MD24	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_000290\|UniProtKB=A0A061DLV4	Theobroma cacao	O
POPTR\|EnsemblGenome=POPTR_007G018700v3\|UniProtKB=B9HFA8	Populus trichocarpa	O
MEDTR\|EnsemblGenome=MTR_8g076490\|UniProtKB=G7LD21	Medicago truncatula	O
POPTR\|EnsemblGenome=POPTR_005G118600v3\|UniProtKB=B9MXK5	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_02G098800\|UniProtKB=A0A2C9WCG4	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_05G154600\|UniProtKB=A0A2C9VWJ2	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_01G140800\|UniProtKB=A0A2C9WM49	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_0533330\|UniProtKB=B9S688	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_01G169700\|UniProtKB=C6SVP6	Glycine max	O
MEDTR\|EnsemblGenome=MTR_5g021260\|UniProtKB=G7KGB6	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr11_20730\|UniProtKB=A0A2I4EP61	Juglans regia	O
JUGRE\|EnsemblGenome=Jr11_07280\|UniProtKB=A0A6P9DTF3	Juglans regia	O
JUGRE\|EnsemblGenome=Jr11_07270\|UniProtKB=A0A2I4ERM3	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_4G045000\|UniProtKB=A0A0A0KUH0	Cucumis sativus	O
SELML\|EnsemblGenome=SELMODRAFT_159187\|UniProtKB=D8SXP0	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_270987\|UniProtKB=D8RNN4	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_172555\|UniProtKB=D8RL54	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c17_2700\|UniProtKB=A0A2K1J2J6	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c15_170\|UniProtKB=A0A7I4AXQ4	Physcomitrella patens	LDO