PANTHER Gene Information

Gene Symbol(s):

GCHFR

Organism:

Canis lupus familiaris

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Gene Name:

GTP cyclohydrolase 1 feedback regulatory protein

Gene ID:

ENSCAFG00845028860.1

Protein ID:

A0A8I3PYY2

Persistent Id:

PTN009032606

Alternate Ids:

XP_544622(refSeq)	74000128(GI)
ENSCAFP00845039997(Ensembl_PRO)	A0A8I3PYY2_CANLF(UniProtKB-ID)
487498(GeneID)	ENSCAFT00845051019(Ensembl_TRS)
ENSCAFG00845028860(Ensembl)	A0A8I3PYY2(Synonym)
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PANTHER Classification

PANTHER Family:	GTP CYCLOHYDROLASE 1 FEEDBACK REGULATORY PROTEIN (PTHR16852)
PANTHER Subfamily:	GTP CYCLOHYDROLASE 1 FEEDBACK REGULATORY PROTEIN (PTHR16852:SF2)
PANTHER GO-slim Molecular Function:	enzyme binding
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	nucleus cytoplasm
PANTHER protein class:	protein-binding activity modulator

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	GTP cyclohydrolase binding
GO BP Complete:	negative regulation of biosynthetic process
GO CC Complete:	nucleus, dendrite, nuclear membrane, cytoplasm, melanosome, cytosol, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation, Metabolism of cofactors, Metabolism, Metabolism of vitamins and cofactors

Orthologs

ID	Organism	Type
HUMAN\|HGNC=4194\|UniProtKB=P30047	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000006928.3\|UniProtKB=H2Q968	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000000050.3\|UniProtKB=G3QCV1	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000047091.2\|UniProtKB=A0A1D5Q6Z4	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2443977\|UniProtKB=P99025	Mus musculus	LDO
RAT\|RGD=621746\|UniProtKB=P70552	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000013477\|UniProtKB=Q32L41	Bos taurus	LDO
HORSE\|Ensembl=ENSECAG00000045773.1\|UniProtKB=A0A9L0R6C2	Equus caballus	LDO
MONDO\|Ensembl=ENSMODG00000000228.3\|UniProtKB=F6SYQ9	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000011955.3\|UniProtKB=F7BIZ2	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010024200.1\|UniProtKB=A0A1D5PZT4	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000041378.1\|UniProtKB=A0A803SN91	Anolis carolinensis	LDO
XENLA\|Gene=gchfr\|UniProtKB=Q6GM84	Xenopus laevis	O
XENLA\|Gene=gchfr.S\|UniProtKB=A0A1L8F482	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-974499\|UniProtKB=Q6NVA8	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000022392.1\|UniProtKB=A0A3B3HK77	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040426-1731\|UniProtKB=Q6PBT6	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000012719.1\|UniProtKB=W5N4U0	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000021776.1\|UniProtKB=H2Y3D9	Ciona intestinalis	LDO
BRAFL\|Gene_ORFName=BRAFLDRAFT_120480\|UniProtKB=C3Z3N9	Branchiostoma floridae	LDO
CAEEL\|WormBase=WBGene00044736\|UniProtKB=D6RYD9	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG01663\|UniProtKB=A8WR49	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00108096\|UniProtKB=A0A2A6CYN7	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00281119\|UniProtKB=A0A454XSY8	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00281114\|UniProtKB=A0A454XXW7	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00206290\|UniProtKB=A0A2A6BID8	Pristionchus pacificus	LDO
PRIPA\|EnsemblGenome=WBGene00095788\|UniProtKB=A0A2A6BVX8	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00095791\|UniProtKB=A0A2A6BVY6	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00275061\|UniProtKB=A0A2A6BPD0	Pristionchus pacificus	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_318384\|UniProtKB=E9GIM5	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW001046\|UniProtKB=B7P5G0	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW001044\|UniProtKB=B7P5F9	Ixodes scapularis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g194136\|UniProtKB=A7SW52	Nematostella vectensis	LDO