PANTHER Gene Information   
Gene Symbol(s): VWF
Organism: Canis lupus familiaris
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Gene Name: von Willebrand factor
Gene ID: ENSCAFG00845029798.1
Protein ID: A0A8I3SCK0
Persistent Id: PTN008965576
Alternate Ids:
ENSCAFT00845053377(Ensembl_TRS) ENSCAFG00845029798(Ensembl)
A0A8I3SCK0(Synonym) A0A8I3SCK0_CANLF(UniProtKB-ID)
ENSCAFP00845041932(Ensembl_PRO)
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PANTHER Classification
PANTHER Family: EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED (PTHR11339)
PANTHER Subfamily: VON WILLEBRAND FACTOR (PTHR11339:SF361)  
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process: blood coagulation
cell-substrate adhesion
PANTHER GO-slim Cellular Component: extracellular space
extracellular matrix
PANTHER protein class: extracellular matrix protein
Pathway Categories: Inflammation mediated by chemokine and cytokine signaling pathway
   ExtraCellular matrix protein
Blood coagulation
   von Willebrand Factor
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: identical protein binding, collagen binding, protein-folding chaperone binding, protease binding, integrin binding, immunoglobulin binding
GO BP Complete: blood coagulation, positive regulation of intracellular signal transduction, cell-substrate adhesion, platelet activation
GO CC Complete: extracellular space, Weibel-Palade body, collagen-containing extracellular matrix, endoplasmic reticulum, extracellular matrix, extracellular region
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: GP1b-IX-V activation signalling, Platelet degranulation , p130Cas linkage to MAPK signaling for integrins, Response to elevated platelet cytosolic Ca2+, Extracellular matrix organization, Platelet activation, signaling and aggregation, MAP2K and MAPK activation, Platelet Adhesion to exposed collagen, RAF/MAP kinase cascade, Signal Transduction, Integrin cell surface interactions, Platelet Aggregation (Plug Formation), Hemostasis, Integrin signaling, MAPK1/MAPK3 signaling, GRB2:SOS provides linkage to MAPK signaling for Integrins , MAPK family signaling cascades

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