PANTHER Gene Information

Gene Symbol(s):

ABCC2

Organism:

Canis lupus familiaris

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Tree

Gene Name:

ABC-type glutathione-S-conjugate transporter

Gene ID:

ENSCAFG00845030901.1

Protein ID:

A0A8I3SCV5

Persistent Id:

PTN000658307

Alternate Ids:

ENSCAFP00845043200(Ensembl_PRO)	A0A8I3SCV5_CANLF(UniProtKB-ID)
ENSCAFT00845054933(Ensembl_TRS)	ENSCAFG00845030901(Ensembl)
A0A8I3SCV5(Synonym)
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PANTHER Classification

PANTHER Family:	ATP-BINDING CASSETTE SUB-FAMILY C (PTHR24223)
PANTHER Subfamily:	ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 2 (PTHR24223:SF176)
PANTHER GO-slim Molecular Function:	ATPase-coupled transmembrane transporter activity
PANTHER GO-slim Biological Process:	transmembrane transport
PANTHER GO-slim Cellular Component:	apical plasma membrane
PANTHER protein class:	ATP-binding cassette (ABC) transporter

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	ATP hydrolysis activity, ATP binding, ATPase-coupled transmembrane transporter activity, ABC-type glutathione S-conjugate transporter activity, ABC-type xenobiotic transporter activity, bilirubin transmembrane transporter activity
GO BP Complete:	xenobiotic transmembrane transport, leukotriene transport, xenobiotic export from cell, transmembrane transport, bilirubin transport, bile acid and bile salt transport
GO CC Complete:	intercellular canaliculus, apical plasma membrane, cell surface

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

ABC-family proteins mediated transport, Paracetamol ADME, Metabolism of porphyrins, Metabolism, Aspirin ADME, Drug ADME, Heme degradation, Atorvastatin ADME, Transport of small molecules

Orthologs

ID	Organism	Type
HUMAN\|HGNC=53\|UniProtKB=Q92887	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000049872.1\|UniProtKB=A0A2I3SLS7	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000002275.3\|UniProtKB=G3RQL0	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000023764.4\|UniProtKB=F7GVK9	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1352447\|UniProtKB=Q8VI47	Mus musculus	LDO
RAT\|RGD=2366\|UniProtKB=Q63120	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000008936.6\|UniProtKB=F1MIP7	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000010543.5\|UniProtKB=F1S8V9	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000019828.4\|UniProtKB=A0A3Q2I0Y3	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000014380.6\|UniProtKB=M3WKM0	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000003389.4\|UniProtKB=F6Z127	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000005819.3\|UniProtKB=F7CKC6	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010022211.1\|UniProtKB=A0A8V0ZMB9	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000003972.4\|UniProtKB=A0A803SKJ9	Anolis carolinensis	LDO
XENLA\|Gene=abcc2.L\|UniProtKB=A0A1L8FJH9	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-1012796\|UniProtKB=A0A6I8S1Y8	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000008249.3\|UniProtKB=H2LW82	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000027419.1\|UniProtKB=H2LW83	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040426-1523\|UniProtKB=F1DB26	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000012775.1\|UniProtKB=W5N530	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000006451.3\|UniProtKB=F6PGX9	Ciona intestinalis	O
BRAFL\|Gene=LOC118428483\|UniProtKB=A0A9J7N971	Branchiostoma floridae	O
BRAFL\|Gene=LOC118428888\|UniProtKB=A0A9J7N8Y3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118428883\|UniProtKB=A0A9J7M5R8	Branchiostoma floridae	O
STRPU\|EnsemblGenome=GeneID_591344\|UniProtKB=I0DHH8	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00003408\|UniProtKB=Q20943	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG08146\|UniProtKB=A8X5X4	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00003407\|UniProtKB=Q3S1M2	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG08145\|UniProtKB=A8X5X3	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00110127\|UniProtKB=A0A2A6D320	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0032456\|UniProtKB=Q7KTC0	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP028128\|UniProtKB=A0A1S4HCW9	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP027980\|UniProtKB=A0A1S4HCJ3	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP008437\|UniProtKB=A0A1S4GY97	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP009835\|UniProtKB=A0A1S4H286	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC012253\|UniProtKB=A0A139WC08	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_347281\|UniProtKB=E9H667	Daphnia pulex	O
HELRO\|EnsemblGenome=HelroG115686\|UniProtKB=T1EGA0	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG95925\|UniProtKB=T1G989	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG105347\|UniProtKB=T1EDT9	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g10039\|UniProtKB=A7SMJ8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g190171\|UniProtKB=A7SII0	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG31533\|UniProtKB=B3S9C1	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG60846\|UniProtKB=B3S9B5	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG60852\|UniProtKB=B3S9C0	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG50946\|UniProtKB=B3S9B6	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG30988\|UniProtKB=B3S839	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG50060\|UniProtKB=B3RSQ0	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG51152\|UniProtKB=B3SCI9	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_18722\|UniProtKB=A9UX43	Monosiga brevicollis	O
EMENI\|EnsemblGenome=ANIA_00015\|UniProtKB=C8VRH1	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_5G00340\|UniProtKB=Q4WDQ9	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU02051\|UniProtKB=Q7SF27	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_11032\|UniProtKB=A7F0B5	Sclerotinia sclerotiorum	O
SCLS1\|EnsemblGenome=SS1G_05336\|UniProtKB=A7EJ43	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_00757\|UniProtKB=Q0V5F7	Phaeosphaeria nodorum	O
EMENI\|EnsemblGenome=ANIA_08150\|UniProtKB=Q5AU80	Emericella nidulans	O
EMENI\|EnsemblGenome=ANIA_07839\|UniProtKB=C8VDW5	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_5G12720\|UniProtKB=Q4WVN3	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU03776\|UniProtKB=F5HEB1	Neurospora crassa	O
EMENI\|EnsemblGenome=ANIA_07879\|UniProtKB=Q5AV01	Emericella nidulans	O
PHANO\|EnsemblGenome=SNOG_14100\|UniProtKB=Q0U1T8	Phaeosphaeria nodorum	O
PHANO\|EnsemblGenome=SNOG_09087\|UniProtKB=Q0UGM7	Phaeosphaeria nodorum	O
EMENI\|EnsemblGenome=ANIA_01240\|UniProtKB=Q5BDZ0	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_1G10390\|UniProtKB=Q4WT65	Neosartorya fumigata	O
SCLS1\|EnsemblGenome=SS1G_03324\|UniProtKB=A7EDD4	Sclerotinia sclerotiorum	O
SCLS1\|EnsemblGenome=SS1G_13112\|UniProtKB=A7F683	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_01112\|UniProtKB=Q0V4F2	Phaeosphaeria nodorum	O
PHANO\|EnsemblGenome=SNOG_14836\|UniProtKB=Q0TZX9	Phaeosphaeria nodorum	O
USTMA\|EnsemblGenome=UMAG_01758\|UniProtKB=A0A0D1CBL8	Ustilago maydis	O
USTMA\|EnsemblGenome=UMAG_15074\|UniProtKB=A0A0D1CW46	Ustilago maydis	O
USTMA\|EnsemblGenome=UMAG_05794\|UniProtKB=A0A0D1BZ25	Ustilago maydis	O
USTMA\|EnsemblGenome=UMAG_15032\|UniProtKB=A0A0D1CSJ1	Ustilago maydis	O
YEAST\|SGD=S000003938\|UniProtKB=P14772	Saccharomyces cerevisiae	O
YEAST\|SGD=S000002542\|UniProtKB=P39109	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AGR047W\|UniProtKB=Q750B0	Eremothecium gossypii	O
CANAL\|CGD=CAL0000183742\|UniProtKB=A0A1D8PTN6	Candida albicans	O
CANAL\|CGD=CAL0000178329\|UniProtKB=Q5A762	Candida albicans	O
CANAL\|CGD=CAL0000179549\|UniProtKB=A0A1D8PR42	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_E08969g\|UniProtKB=Q6C6J9	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_F31845g\|UniProtKB=Q6BZQ2	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_A19580g\|UniProtKB=Q6CGG4	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_C18051g\|UniProtKB=Q6CBK3	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_F12089g\|UniProtKB=Q6C1Z6	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_E25069g\|UniProtKB=Q6C4N2	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_03472\|UniProtKB=Q5B7K8	Emericella nidulans	O
EMENI\|EnsemblGenome=ANIA_07729\|UniProtKB=Q5AVF1	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_5G07970\|UniProtKB=Q4WUC5	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU09012\|UniProtKB=Q7S0S1	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_07453\|UniProtKB=A7EQ53	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_09278\|UniProtKB=Q0UG36	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPBC359.05\|UniProtKB=Q9P5N0	Schizosaccharomyces pombe	O
SCHPO\|PomBase=SPAC3F10.11c\|UniProtKB=Q10185	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_01344\|UniProtKB=B6K0F0	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CNC05860\|UniProtKB=Q5KJN9	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_10365\|UniProtKB=A0A0D1DYC7	Ustilago maydis	O
USTMA\|EnsemblGenome=UMAG_02568\|UniProtKB=A0A0D1E417	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_14463\|UniProtKB=E3KVN9	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_14456\|UniProtKB=E3KVN2	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_9753\|UniProtKB=F4NVY7	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_14605\|UniProtKB=F4PDI2	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_88614\|UniProtKB=F4P3J1	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_18172\|UniProtKB=F4NRK4	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_92730\|UniProtKB=F4PEH2	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_20822\|UniProtKB=F4PBV3	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_18633\|UniProtKB=F4NTL2	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_16805\|UniProtKB=F4P4C1	Batrachochytrium dendrobatidis	O
ENTH1\|EnsemblGenome=CL6EHI_124840\|UniProtKB=C4M978	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0284867\|UniProtKB=Q54P13	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_47315\|UniProtKB=F0ZIX3	Dictyostelium purpureum	O
PARTE\|EnsemblGenome=GSPATT00001809001\|UniProtKB=A0D6V1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00028165001\|UniProtKB=A0BF13	Paramecium tetraurelia	O
PHYRM\|Gene=H3HEF0_PHYRM\|UniProtKB=H3HEF0	Phytophthora ramorum	O
PHYRM\|Gene=H3HCF6_PHYRM\|UniProtKB=H3HCF6	Phytophthora ramorum	O
PHYRM\|Gene=H3HD40_PHYRM\|UniProtKB=H3HD40	Phytophthora ramorum	O
PHYRM\|Gene=H3HE07_PHYRM\|UniProtKB=H3HE07	Phytophthora ramorum	O
PHYRM\|Gene=H3GAE6_PHYRM\|UniProtKB=H3GAE6	Phytophthora ramorum	O
PHYRM\|Gene=H3HD38_PHYRM\|UniProtKB=H3HD38	Phytophthora ramorum	O
PHYRM\|Gene=H3H408_PHYRM\|UniProtKB=H3H408	Phytophthora ramorum	O
PHYRM\|Gene=H3GKM1_PHYRM\|UniProtKB=H3GKM1	Phytophthora ramorum	O
PHYRM\|Gene=H3GJD8_PHYRM\|UniProtKB=H3GJD8	Phytophthora ramorum	O
PHYRM\|Gene=H3H2W5_PHYRM\|UniProtKB=H3H2W5	Phytophthora ramorum	O
PHYRM\|Gene=H3H5U8_PHYRM\|UniProtKB=H3H5U8	Phytophthora ramorum	O
PHYRM\|Gene=H3HE89_PHYRM\|UniProtKB=H3HE89	Phytophthora ramorum	O
PHYRM\|Gene=H3GAR7_PHYRM\|UniProtKB=H3GAR7	Phytophthora ramorum	O
PHYRM\|Gene=H3G9K9_PHYRM\|UniProtKB=H3G9K9	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_08g369720v5\|UniProtKB=A0A2K3DH39	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_07g325761v5\|UniProtKB=A0A2K3DJI3	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_08g369850v5\|UniProtKB=A0A2K3DH80	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_03g174050v5\|UniProtKB=A0A2K3DX98	Chlamydomonas reinhardtii	O
KLENI\|Gene_ORFName=KFL_003420130\|UniProtKB=A0A1Y1I8H3	Klebsormidium nitens	O
CHLRE\|EnsemblGenome=CHLRE_02g097800v5\|UniProtKB=A0A2K3E226	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_17g734612v5\|UniProtKB=Q50JT7	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_13g564900v5\|UniProtKB=A0A2K3CZ64	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_02g103250v5\|UniProtKB=A0A2K3E2F8	Chlamydomonas reinhardtii	O
MARPO\|EnsemblGenome=MARPO_0133s0051\|UniProtKB=A0A2R6W7S7	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_004930030\|UniProtKB=A0A1Y1IDX7	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_000850340\|UniProtKB=A0A1Y1I0J0	Klebsormidium nitens	O