PANTHER Gene Information

Gene Symbol(s):

PRKCH

Organism:

Gallus gallus

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Gene Name:

Protein kinase C

Gene ID:

ENSGALG00010017816.1

Protein ID:

F1NJH1

Persistent Id:

PTN001968786

Alternate Ids:

423518(GeneID)	F1NJH1_CHICK(UniProtKB-ID)
ENSGALT00010043056(Ensembl_TRS)	ENSGALP00010025546(Ensembl_PRO)
ENSGALG00010017816(Ensembl)	F1NJH1(Synonym)
XP_421417(refSeq)	971400598(GI)
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PANTHER Classification

PANTHER Family:	SERINE/THREONINE-PROTEIN KINASE (PTHR24356)
PANTHER Subfamily:	PROTEIN KINASE C ETA TYPE (PTHR24356:SF192)
PANTHER GO-slim Molecular Function:	protein serine/threonine kinase activity
PANTHER GO-slim Biological Process:	peptidyl-serine phosphorylation intracellular signal transduction
PANTHER GO-slim Cellular Component:
PANTHER protein class:	non-receptor serine/threonine protein kinase

Pathway Categories:

Histamine H1 receptor mediated signaling pathway

Protein kinase C

Thyrotropin-releasing hormone receptor signaling pathway

Protein kinase C

FGF signaling pathway

Protein kinase C

Angiogenesis

Protein kinase B

Apoptosis signaling pathway

Protein kinase C

CCKR signaling map

PKCeta

Endothelin signaling pathway

protein kinase c

VEGF signaling pathway

Protein kinase C

Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway

Protein kinase C

Alzheimer disease-amyloid secretase pathway

Protein kinase C

EGF receptor signaling pathway

PKC

5HT2 type receptor mediated signaling pathway

Protein kinase C

Wnt signaling pathway

Protein Kinase C

Muscarinic acetylcholine receptor 1 and 3 signaling pathway

Protein kinase C

Oxytocin receptor mediated signaling pathway

Protein kinase C

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity, ATP binding, metal ion binding, small GTPase binding, protein serine/threonine kinase activity, calcium,diacylglycerol-dependent serine/threonine kinase activity
GO BP Complete:	positive regulation of keratinocyte differentiation, positive regulation of B cell receptor signaling pathway, negative regulation of glial cell apoptotic process, positive regulation of glial cell proliferation, positive regulation of macrophage derived foam cell differentiation, regulation of bicellular tight junction assembly, intracellular signal transduction
GO CC Complete:	cell-cell junction, cytosol, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Effects of PIP2 hydrolysis, G alpha (q) signalling events, Hemostasis, Signaling by GPCR, GPCR downstream signalling, Platelet activation, signaling and aggregation, Signal Transduction

Orthologs

ID	Organism	Type
HUMAN\|HGNC=9403\|UniProtKB=P24723	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000006418.3\|UniProtKB=H2Q8F2	Pan troglodytes	LDO
MACMU\|Ensembl=ENSMMUG00000002260.4\|UniProtKB=F7BUZ8	Macaca mulatta	LDO
MOUSE\|MGI=MGI=97600\|UniProtKB=P23298	Mus musculus	LDO
RAT\|RGD=621888\|UniProtKB=Q64617	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000003276.5\|UniProtKB=F1MY82	Bos taurus	LDO
HORSE\|Ensembl=ENSECAG00000013529.3\|UniProtKB=A0A9L0TQ16	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000012900.6\|UniProtKB=M3WHU4	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845023062.1\|UniProtKB=A0A8I3PGY9	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000008706.4\|UniProtKB=F6PWG0	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000009091.3\|UniProtKB=F7G7C3	Ornithorhynchus anatinus	LDO
ANOCA\|Ensembl=ENSACAG00000006398.4\|UniProtKB=A0A803TIK6	Anolis carolinensis	LDO
DANRE\|ZFIN=ZDB-GENE-041001-104\|UniProtKB=A0A2R8Q5P7	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-080402-5\|UniProtKB=B1H1I7	Danio rerio	LDO
BRAFL\|Gene=LOC118413941\|UniProtKB=A0A9J7L0A2	Branchiostoma floridae	O
CAEEL\|WormBase=WBGene00004032\|UniProtKB=P34885	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG23354\|UniProtKB=A8Y443	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00117214\|UniProtKB=A0A2A6CRU5	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0003093\|UniProtKB=P13678	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP002748\|UniProtKB=A0A1S4GFU0	Anopheles gambiae	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_301963\|UniProtKB=E9GB27	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW004410\|UniProtKB=B7PJ72	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG64769\|UniProtKB=T1FXY8	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g245970\|UniProtKB=A7SL27	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG30067\|UniProtKB=B3S6K6	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_31267\|UniProtKB=A9USR5	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_10752\|UniProtKB=A9V750	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_21555\|UniProtKB=A9V1T6	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_34036\|UniProtKB=A9V9H6	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_39232\|UniProtKB=A9VD19	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_20766\|UniProtKB=A9UXQ2	Monosiga brevicollis	O
YEAST\|SGD=S000000201\|UniProtKB=P24583	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ACR191C\|UniProtKB=Q75BT0	Eremothecium gossypii	O
CANAL\|CGD=CAL0000201435\|UniProtKB=Q5ANK2	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_F09746g\|UniProtKB=Q6C292	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_00106\|UniProtKB=C8VQM0	Emericella nidulans	O
NEUCR\|EnsemblGenome=NCU06544\|UniProtKB=P87253	Neurospora crassa	O
PHANO\|EnsemblGenome=SNOG_07073\|UniProtKB=Q0UME1	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPAC17G8.14c\|UniProtKB=P36582	Schizosaccharomyces pombe	O
SCHPO\|PomBase=SPBC12D12.04c\|UniProtKB=P36583	Schizosaccharomyces pombe	O
CRYNJ\|EnsemblGenome=CNE01630\|UniProtKB=Q5KH12	Cryptococcus neoformans	O
CRYNJ\|EnsemblGenome=CNC03300\|UniProtKB=Q5KKE3	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_15023\|UniProtKB=A0A0D1DRE2	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_12641\|UniProtKB=E3KRH5	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_15370\|UniProtKB=F4NTP5	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_19449\|UniProtKB=F4P170	Batrachochytrium dendrobatidis	O
ENTH1\|EnsemblGenome=CL6EHI_125820\|UniProtKB=C4LVW8	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_097620\|UniProtKB=C4M933	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_188930\|UniProtKB=C4M2W0	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_044470\|UniProtKB=B1N2G7	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_042150\|UniProtKB=C4M4G9	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_053040\|UniProtKB=C4M3C2	Entamoeba histolytica	O
ENTH1\|Gene_ORFName=EHI_138540\|UniProtKB=A0A8U0WPI4	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0288795\|UniProtKB=Q54IF2	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_149347\|UniProtKB=F0ZDG7	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0268620\|UniProtKB=P54644	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_152431\|UniProtKB=F0ZLC3	Dictyostelium purpureum	O
DICPU\|EnsemblGenome=DICPUDRAFT_38849\|UniProtKB=F0ZVB0	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_30_0800\|UniProtKB=Q4Q7M5	Leishmania major	O
TRYB2\|Gene_ORFName=Tb11.01.2290\|UniProtKB=Q383M7	Trypanosoma brucei	O
TRYB2\|Gene_ORFName=Tb927.3.2690\|UniProtKB=Q582Y1	Trypanosoma brucei	O
GIAIC\|EnsemblGenome=GL50803_11364\|UniProtKB=E2RTY0	Giardia intestinalis	O
TRIV3\|Gene_ORFName=TVAG_195270\|UniProtKB=A2FLX7	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_324020\|UniProtKB=A2F4A4	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_430560\|UniProtKB=A2E382	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_316050\|UniProtKB=A2FAW3	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_447920\|UniProtKB=A2DS63	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_047250\|UniProtKB=A2FHJ2	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_267830\|UniProtKB=A2DLD2	Trichomonas vaginalis	O
SACS2\|EnsemblGenome=SSO3207\|UniProtKB=Q97U18	Sulfolobus solfataricus	O