PANTHER Gene Information

Gene Symbol(s):

KCNJ5

Organism:

Gallus gallus

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Gene Name:

G protein-activated inward rectifier potassium channel 4

Gene ID:

ENSGALG00010023437.1

Protein ID:

F1P3M0

Persistent Id:

PTN000205751

Alternate Ids:

ENSGALT00010057107(Ensembl_TRS)	395925(GeneID)
ENSGALG00010023437(Ensembl)	F1P3M0(Synonym)
118101864(GI)	XM_417864(refSeq)
ENSGALP00010034738(Ensembl_PRO)	F1P3M0_CHICK(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	INWARD RECTIFIER POTASSIUM CHANNEL (PTHR11767)
PANTHER Subfamily:	G PROTEIN-ACTIVATED INWARD RECTIFIER POTASSIUM CHANNEL 4 (PTHR11767:SF52)
PANTHER GO-slim Molecular Function:	voltage-gated potassium channel activity ligand-gated monoatomic cation channel activity
PANTHER GO-slim Biological Process:	potassium ion import across plasma membrane regulation of monoatomic ion transmembrane transport
PANTHER GO-slim Cellular Component:	plasma membrane
PANTHER protein class:	ion channel

Pathway Categories:

Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway

G-protein receptor kinase

Muscarinic acetylcholine receptor 2 and 4 signaling pathway

G protein-coupled inwardly rectifying potassium channel

Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway

G protein-activated inward rectifying potassium channel

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	G-protein activated inward rectifier potassium channel activity, voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization, inward rectifier potassium channel activity
GO BP Complete:	potassium ion import across plasma membrane, regulation of monoatomic ion transmembrane transport, membrane repolarization during atrial cardiac muscle cell action potential, regulation of heart rate by cardiac conduction
GO CC Complete:	voltage-gated potassium channel complex, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Neuronal System, Transmission across Chemical Synapses, Neurotransmitter receptors and postsynaptic signal transmission, Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits, Potassium Channels, Inwardly rectifying K+ channels, Activation of G protein gated Potassium channels, G protein gated Potassium channels, GABA receptor activation, Activation of GABAB receptors, GABA B receptor activation

Orthologs

ID	Organism	Type
HUMAN\|HGNC=6266\|UniProtKB=P48544	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000048168.1\|UniProtKB=A0A2J8N158	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000028551.2\|UniProtKB=G3S2K8	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000003145.4\|UniProtKB=A0A5F7ZJ09	Macaca mulatta	LDO
MOUSE\|MGI=MGI=104755\|UniProtKB=P48545	Mus musculus	LDO
RAT\|RGD=61971\|UniProtKB=P48548	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000006902\|UniProtKB=F1MYR9	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000021573\|UniProtKB=O02670	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000025007.4\|UniProtKB=F6RSN5	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000035352.3\|UniProtKB=A0A2I2UE47	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000004783.4\|UniProtKB=F6WK38	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000000571.2\|UniProtKB=F7FBI5	Ornithorhynchus anatinus	LDO
ANOCA\|Ensembl=ENSACAG00000024629.3\|UniProtKB=H9GTA0	Anolis carolinensis	LDO
XENLA\|Gene=kcnj5.L\|UniProtKB=Q91658	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-5919506\|UniProtKB=A0A6I8PTT1	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000027135.1\|UniProtKB=A0A3B3IEQ7	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-120215-97\|UniProtKB=A0A0R4IAD0	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000002615.1\|UniProtKB=W5M3W8	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000023776.1\|UniProtKB=F6XQI0	Ciona intestinalis	LDO
BRAFL\|Gene_ORFName=BRAFLDRAFT_121818\|UniProtKB=C3YD60	Branchiostoma floridae	O
BRAFL\|Gene=LOC118426070\|UniProtKB=A0A9J7N316	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC584140\|UniProtKB=A0A7M7NLD4	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115918598\|UniProtKB=A0A7M7NRA6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC584158\|UniProtKB=A0A7M7NRN0	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC592565\|UniProtKB=A0A7M7LSG3	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00002151\|UniProtKB=A0A1C3NSK2	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG10649\|UniProtKB=A8XBI7	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00096471\|UniProtKB=A0A2A6B4B2	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00002149\|UniProtKB=P52192	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG10884\|UniProtKB=A8XC74	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00002150\|UniProtKB=A0A1C3NSN6	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG08126\|UniProtKB=A8X5V6	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00203627\|UniProtKB=A0A2A6CGW5	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0032706\|UniProtKB=B7YZX2	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP007818\|UniProtKB=A0A1S4GX11	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP028144\|UniProtKB=A0A1S4HEA1	Anopheles gambiae	O
DROME\|FlyBase=FBgn0039081\|UniProtKB=A0A0B4LHI9	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP001283\|UniProtKB=Q7PX91	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP001284\|UniProtKB=Q7PKL0	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP001281\|UniProtKB=Q7PKK8	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC034483\|UniProtKB=A0A139WBX6	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC006707\|UniProtKB=D6WYJ8	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC033608\|UniProtKB=A0A139WFH2	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC006708\|UniProtKB=D6WYJ9	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC001199\|UniProtKB=D6WAQ3	Tribolium castaneum	O
DROME\|FlyBase=FBgn0265042\|UniProtKB=A0A0B4KH86	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP029806\|UniProtKB=A0A499FWX7	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC006706\|UniProtKB=D6WYJ7	Tribolium castaneum	O
DAPPU\|Gene_ORFName=DAPPUDRAFT_42289\|UniProtKB=E9FXS2	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_311738\|UniProtKB=E9FXS0	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW016219\|UniProtKB=B7P0N6	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG107917\|UniProtKB=T1EED8	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG157415\|UniProtKB=T1EMB1	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG179553\|UniProtKB=T1FEV3	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG122541\|UniProtKB=T1EGU9	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG79786\|UniProtKB=T1G3T3	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG73033\|UniProtKB=T1G190	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG108208\|UniProtKB=T1EEG9	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG82781\|UniProtKB=T1G4W5	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG122071\|UniProtKB=T1EGT8	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG82544\|UniProtKB=T1G4T5	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG122255\|UniProtKB=T1EGU3	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG106279\|UniProtKB=T1EE13	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g52170\|UniProtKB=A7SE20	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g170615\|UniProtKB=A7SH65	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g101684\|UniProtKB=A7S217	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g93919\|UniProtKB=A7RUM3	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG3835\|UniProtKB=B3RMY4	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_25718\|UniProtKB=A9V082	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_24696\|UniProtKB=A9UX72	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_32445\|UniProtKB=A9UZJ5	Monosiga brevicollis	O
LEIMA\|EnsemblGenome=LMJF_09_0480\|UniProtKB=Q4QHX6	Leishmania major	O
TRYB2\|Gene_ORFName=Tb11.01.4330\|UniProtKB=Q382T2	Trypanosoma brucei	O
THAPS\|EnsemblGenome=THAPS_25330\|UniProtKB=B5YLJ0	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_24946\|UniProtKB=B8CCX1	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_21089\|UniProtKB=B8BSL6	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_5256\|UniProtKB=B8C2E6	Thalassiosira pseudonana	O
PHYRM\|Gene=H3HCM1_PHYRM\|UniProtKB=H3HCM1	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_01g035800v5\|UniProtKB=A0A2K3E712	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_06g311650v5\|UniProtKB=A0A2K3DRT3	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_13g591450v5\|UniProtKB=A0A2K3D141	Chlamydomonas reinhardtii	O
PHYPA\|EnsemblGenome=Pp3c15_3810\|UniProtKB=A0A7I3Z5Z2	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c9_4440\|UniProtKB=A0A2K1K204	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0015s0176\|UniProtKB=A0A2R6XH25	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_005570020\|UniProtKB=A0A1Y1II39	Klebsormidium nitens	O