PANTHER Gene Information

Gene Symbol(s):

CATHL1

Organism:

Gallus gallus

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Gene Name:

Cathelicidin-1

Gene ID:

ENSGALG00010025943

Protein ID:

Q6QLQ5

Persistent Id:

PTN001610744

Alternate Ids:

82087686(GI)	CATH(Synonym)
AAZ65841(EMBL-CDS)	ENSGALG00010025943(Ensembl)
ENSGALP00015036000(Ensembl_PRO)	414337(GeneID)
CATHL1(Symbol)	NM_001001605(refSeq)
AB308318(EMBL)	ENSGALT00015059270(Ensembl_TRS)
Q2IAM1(AltAccession)	CTHL1_CHICK(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	CATHELICIDIN (PTHR10206)
PANTHER Subfamily:	CATHELICIDIN B1-RELATED (PTHR10206:SF0)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	extracellular space
PANTHER protein class:	antimicrobial response protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	membrane destabilizing activity, lipopolysaccharide binding
GO BP Complete:	positive regulation of adaptive immune response, defense response to Gram-negative bacterium, innate immune response, neutrophil chemotaxis, antibacterial innate immune response, positive regulation of cytokine production involved in inflammatory response, macrophage activation, positive regulation of MHC class II biosynthetic process, defense response to Gram-positive bacterium, antimicrobial humoral immune response mediated by antimicrobial peptide
GO CC Complete:	extracellular space

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Neutrophil degranulation, Innate Immune System, Antimicrobial peptides, Immune System

Orthologs

ID	Organism	Type
HUMAN\|HGNC=1472\|UniProtKB=P49913	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000014880.4\|UniProtKB=A0A2J8PA57	Pan troglodytes	O
PANTR\|Gene=CAMP\|UniProtKB=Q1KLX1	Pan troglodytes	O
GORGO\|Gene=CAMP\|UniProtKB=Q1KLY3	Gorilla gorilla gorilla	O
GORGO\|Ensembl=ENSGGOG00000012414.3\|UniProtKB=A0A2K5TIY0	Gorilla gorilla gorilla	O
MACMU\|Gene=CAMP\|UniProtKB=Q9GLV5	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000010655.4\|UniProtKB=F7B5V0	Macaca mulatta	O
MOUSE\|MGI=MGI=108443\|UniProtKB=P51437	Mus musculus	O
RAT\|RGD=1559878\|UniProtKB=G3V8S9	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000039879.2\|UniProtKB=G8JKZ9	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000013356\|UniProtKB=P22226	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000024852\|UniProtKB=P19660	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000003022\|UniProtKB=P56425	Bos taurus	O
BOVIN\|Gene=CATHL5\|UniProtKB=P54229	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000031594.3\|UniProtKB=E1BL84	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000049629\|UniProtKB=P54228	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000016153.6\|UniProtKB=A0A3Q1MZC7	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000020076.4\|UniProtKB=A0A452DIN2	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000052903\|UniProtKB=P33046	Bos taurus	O
PIG\|Ensembl=ENSSSCG00070005376\|UniProtKB=P80054	Sus scrofa	O
PIG\|Gene=NPG2\|UniProtKB=P32195	Sus scrofa	O
PIG\|Gene=NPG3\|UniProtKB=P32196	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000031673.1\|UniProtKB=A0A287AWM1	Sus scrofa	O
PIG\|Gene=ICTL_PIG\|UniProtKB=P15175	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000052537.1\|UniProtKB=A0A5G2QU73	Sus scrofa	O
PIG\|Gene=PMAP23\|UniProtKB=P49930	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00070005556\|UniProtKB=P32194	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000057676.1\|UniProtKB=A0A8W4FPD4	Sus scrofa	O
PIG\|Gene=NPG4\|UniProtKB=P49933	Sus scrofa	O
PIG\|Gene=PF11_PIG\|UniProtKB=P51524	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000045208.2\|UniProtKB=A0A5G2QHA2	Sus scrofa	O
PIG\|Gene=PF12_PIG\|UniProtKB=P51525	Sus scrofa	O
PIG\|Gene=PMAP37\|UniProtKB=P49932	Sus scrofa	O
PIG\|Gene=NPG5\|UniProtKB=P49934	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000047135.2\|UniProtKB=A0A5G2QDH1	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000052645.1\|UniProtKB=A0A286ZKJ1	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000063400.1\|UniProtKB=A0A287B046	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000052135.1\|UniProtKB=A0A287AFU9	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000053313.1\|UniProtKB=A0A5G2QNY2	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000059830.1\|UniProtKB=A0A8W4FB67	Sus scrofa	O
PIG\|Gene=PMAP36\|UniProtKB=P49931	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000013712.3\|UniProtKB=F7ARG5	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000029296.2\|UniProtKB=A0A3Q2HN88	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000016046.4\|UniProtKB=A0A9L0TAT0	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000008790.4\|UniProtKB=F1C962	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845007235.1\|UniProtKB=Q6TN20	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000028307.2\|UniProtKB=K7E665	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000027493.2\|UniProtKB=K7E365	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000036406.1\|UniProtKB=A0A5F8HHS2	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000042431.1\|UniProtKB=A0A5F8G7A6	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000038114.1\|UniProtKB=A0A5F8GUW0	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000014312.3\|UniProtKB=F6W4B4	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000028095.2\|UniProtKB=K7E2B6	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000028672.2\|UniProtKB=K7E235	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000004262.2\|UniProtKB=F7ARW0	Ornithorhynchus anatinus	O
ORNAN\|Ensembl=ENSOANG00000010609.3\|UniProtKB=F7A8G5	Ornithorhynchus anatinus	O
ORNAN\|Ensembl=ENSOANG00000050324.1\|UniProtKB=A0A6I8NY70	Ornithorhynchus anatinus	O
ORNAN\|Ensembl=ENSOANG00000011030.2\|UniProtKB=F7CWF3	Ornithorhynchus anatinus	O
ORNAN\|Ensembl=ENSOANG00000010610.3\|UniProtKB=F7A8F8	Ornithorhynchus anatinus	O
ORNAN\|Ensembl=ENSOANG00000039837.1\|UniProtKB=A0A6I8PBW4	Ornithorhynchus anatinus	O
ORNAN\|Ensembl=ENSOANG00000046196.1\|UniProtKB=A0A6I8PM85	Ornithorhynchus anatinus	O
ANOCA\|Ensembl=ENSACAG00000006634.4\|UniProtKB=A0A803TW99	Anolis carolinensis	O
LEPOC\|Ensembl=ENSLOCG00000009256.1\|UniProtKB=W5MSD0	lepisosteus oculatus	O