PANTHER Gene Information

Gene Symbol(s):

lepA

Organism:

Clostridium botulinum

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Gene Name:

Elongation factor 4

Gene ID:

CBO2963

Protein ID:

A5I644

Persistent Id:

PTN001897109

Alternate Ids:

EF-4 {ECO:0000255\|HAMAP-Rule:MF_00071}(Synonym)	5186162(GeneID)
LEPA_CLOBH(UniProtKB-ID)	148290399(GI)
lepA{ECO:0000255\|HAMAP-Rule:MF_00071}(Symbol)	YP_001388692(refSeq)
3.6.5.n1 {ECO:0000255\|HAMAP-Rule:MF_00071}(EC)	CP000727(EMBL)
A7G7C7(AltAccession)	ABS38795(EMBL-CDS)
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PANTHER Classification

PANTHER Family:	TRANSLATION FACTOR GUF1-RELATED (PTHR43512)
PANTHER Subfamily:	TRANSLATION FACTOR GUF1 HOMOLOG, CHLOROPLASTIC (PTHR43512:SF4)
PANTHER GO-slim Molecular Function:	ribosome binding
PANTHER GO-slim Biological Process:	positive regulation of translation
PANTHER GO-slim Cellular Component:
PANTHER protein class:	translation initiation factor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	GTP binding, translation elongation factor activity, GTPase activity, ribosome binding, hydrolase activity
GO BP Complete:	positive regulation of translation, translational elongation, translation
GO CC Complete:	plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=25799\|UniProtKB=Q8N442	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000016022.5\|UniProtKB=A0A2I3S7N3	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000001699.3\|UniProtKB=G3SBM5	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000009270.4\|UniProtKB=F7H645	Macaca mulatta	O
MOUSE\|MGI=MGI=2140726\|UniProtKB=Q8C3X4	Mus musculus	O
RAT\|RGD=1310774\|UniProtKB=D3ZHF8	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000000285.6\|UniProtKB=A0A452DHP0	Bos taurus	O
BOVIN\|Gene=GUF1\|UniProtKB=A6QLJ3	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000008807.5\|UniProtKB=F1S3T1	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000019296.3\|UniProtKB=F7BKM0	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000028580.4\|UniProtKB=M3WQG6	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845015394.1\|UniProtKB=A0A8I3P008	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000020592.4\|UniProtKB=F7A0N4	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000007142.3\|UniProtKB=F7CM81	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010013823.1\|UniProtKB=A0A8V0YFJ1	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000007056.4\|UniProtKB=G1KG38	Anolis carolinensis	O
XENLA\|Gene=guf1.L\|UniProtKB=A0A1L8HTV3	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-983364\|UniProtKB=A0A6I8RRL2	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000009541.2\|UniProtKB=H2M0N6	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-030131-4289\|UniProtKB=E7FFK6	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000012397.1\|UniProtKB=W5N3R0	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000003163.3\|UniProtKB=F6QIK7	Ciona intestinalis	O
BRAFL\|Gene=LOC118419119\|UniProtKB=A0A9J7LFT6	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC586213\|UniProtKB=A0A7M7SWH9	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00022862\|UniProtKB=P34617	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00037611\|UniProtKB=A8XT37	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00102731\|UniProtKB=A0A2A6BW77	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0024182\|UniProtKB=Q9VRH6	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP009971\|UniProtKB=A0A1S4H2L6	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC007205\|UniProtKB=A0A139WJE5	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_49405\|UniProtKB=E9GF27	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW003920\|UniProtKB=B7PJS6	Ixodes scapularis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g106275\|UniProtKB=A7S680	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG56304\|UniProtKB=B3RXR7	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_9705\|UniProtKB=A9V3I8	Monosiga brevicollis	O
YEAST\|SGD=S000004280\|UniProtKB=P46943	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AGR290W\|UniProtKB=Q74ZG2	Eremothecium gossypii	O
CANAL\|CGD=CAL0000194371\|UniProtKB=Q59P53	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_F10725g\|UniProtKB=Q6C255	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_10315\|UniProtKB=C8VPJ1	Emericella nidulans	O
ASPFU\|Gene_ORFName=AFUA_3G14350\|UniProtKB=Q4WYV0	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU05927\|UniProtKB=Q7S0P6	Neurospora crassa	O
SCLS1\|Gene_ORFName=SS1G_10621\|UniProtKB=A7EZ55	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_01420\|UniProtKB=Q0V3J4	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPAC1B3.04c\|UniProtKB=O13869	Schizosaccharomyces pombe	O
SCHJY\|Gene_ORFName=SJAG_04351\|UniProtKB=B6K6L6	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CNL06110\|UniProtKB=Q5K8D2	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_01891\|UniProtKB=A0A0D1E4W6	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_15171\|UniProtKB=E3KX95	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_87956\|UniProtKB=F4P1R2	Batrachochytrium dendrobatidis	O
DICDI\|dictyBase=DDB_G0291708\|UniProtKB=B0G189	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_43053\|UniProtKB=F1A3D1	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_34_0570\|UniProtKB=Q4Q3F0	Leishmania major	O
TRYB2\|Gene_ORFName=Tb10.70.4600\|UniProtKB=Q38BU9	Trypanosoma brucei	O
PARTE\|EnsemblGenome=GSPATT00004120001\|UniProtKB=A0ED84	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_31665\|UniProtKB=B8BPV6	Thalassiosira pseudonana	O
PHYRM\|Gene=H3G5E1_PHYRM\|UniProtKB=H3G5E1	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_03g174000v5\|UniProtKB=A0A2K3DX99	Chlamydomonas reinhardtii	O
ZOSMR\|Gene_ORFName=ZOSMA_150G00370\|UniProtKB=A0A0K9PWC8	Zostera marina	O
MUSAM\|EnsemblGenome=Ma10_g21010\|UniProtKB=A0A804KYK6	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_006016mg\|UniProtKB=K3XVQ8	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3010G034100\|UniProtKB=C5Z3W1	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb377210\|UniProtKB=A0A804QYQ1	Zea mays	O
ORYSJ\|EnsemblGenome=Os06g0144800\|UniProtKB=Q5VQ69	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_1g51240v3\|UniProtKB=I1H1Q1	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.7HG0648600\|UniProtKB=A0A8I7BD59	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS4A02G386100\|UniProtKB=A0A3B6I274	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7D02G081700\|UniProtKB=A0A3B6TK09	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7A02G087200\|UniProtKB=A0A3B6R8N7	Triticum aestivum	O
NELNU\|Gene_ORFName=HUJ06_010033\|UniProtKB=A0A1U7YWP0	Nelumbo nucifera	O
SPIOL\|Gene=LOC110796750\|UniProtKB=A0A9R0IXR5	Spinacia oleracea	O
HELAN\|EnsemblGenome=HanXRQr2_Chr09g0401901\|UniProtKB=A0A251U0X3	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C400225520\|UniProtKB=A0A9R1VWT3	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a002517mg\|UniProtKB=A0A022R3C1	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_12105\|UniProtKB=A0A2G2ZNU0	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400013207\|UniProtKB=M1B0I3	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc03g058880.3\|UniProtKB=A0A3Q7G7B6	Solanum lycopersicum	O
TOBAC\|Gene=LOC107801746\|UniProtKB=A0A1S4AVA7	Nicotiana tabacum	O
TOBAC\|Gene=LOC107803086\|UniProtKB=A0A1S4AZR0	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi14g01908\|UniProtKB=F6H5P1	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_J01223\|UniProtKB=A0A059ADN3	Eucalyptus grandis	O
BRANA\|Gene_ORFName=DARMORV10_C06P18790.1\|UniProtKB=A0A078JF71	Brassica napus	O
BRACM\|EnsemblGenome=Bra028444\|UniProtKB=M4EI29	Brassica campestris	O
ARATH\|TAIR=locus=2178042\|UniProtKB=Q9FLE4	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107892371\|UniProtKB=A0A1U8IAX8	Gossypium hirsutum	O
GOSHI\|Gene=LOC107892331\|UniProtKB=A0A1U8I3S1	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_045800\|UniProtKB=S1SI39	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g008991mg\|UniProtKB=A0A067FYT1	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_017G079800v3\|UniProtKB=B9IJU6	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_17G023200\|UniProtKB=A0A251ITR2	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_0855130\|UniProtKB=B9RUN8	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_09G258100\|UniProtKB=K7LG40	Glycine max	O
MEDTR\|EnsemblGenome=MTR_7g009740\|UniProtKB=G7KZV0	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr10_02330\|UniProtKB=A0A2I4FWD8	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_5G635420\|UniProtKB=A0A0A0KVI1	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_3G270700\|UniProtKB=M5WR91	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_231087\|UniProtKB=D8R939	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_230251\|UniProtKB=D8QYJ7	Selaginella moellendorffii	O
MARPO\|EnsemblGenome=MARPO_0004s0135\|UniProtKB=A0A2R6XS00	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_001140050\|UniProtKB=A0A1Y1I167	Klebsormidium nitens	O
PLAF7\|EnsemblGenome=PF3D7_0911700\|UniProtKB=Q8I335	Plasmodium falciparum	LDO
CHLRE\|EnsemblGenome=CHLRE_03g165000v5\|UniProtKB=A0A2K3DWN1	Chlamydomonas reinhardtii	LDO
CHLAA\|EnsemblGenome=Caur_3061\|UniProtKB=A9WGU4	Chloroflexus aurantiacus	LDO
STRCO\|Gene_OrderedLocusName=SCO2562\|UniProtKB=Q9RDC9	Streptomyces coelicolor	LDO
MYCTU\|Gene_OrderedLocusName=Rv2404c\|UniProtKB=P9WK97	Mycobacterium tuberculosis	LDO
MYCGE\|EnsemblGenome=MG_138\|UniProtKB=P47384	mycoplasma genitalium	LDO
STRR6\|EnsemblGenome=spr1082\|UniProtKB=Q8DPN5	Streptococcus pneumoniae	LDO
STAA8\|EnsemblGenome=SAOUHSC_01688\|UniProtKB=Q2FXY7	Staphylococcus aureus	LDO
LISMO\|EnsemblGenome=CAC99557\|UniProtKB=Q8Y742	Listeria monocytogenes	LDO
BACSU\|EnsemblGenome=BSU_25510\|UniProtKB=P37949	Bacillus subtilis	LDO
BACCR\|EnsemblGenome=BC_4317\|UniProtKB=Q818E4	Bacillus cereus	LDO
THEMA\|EnsemblGenome=TM_1623\|UniProtKB=Q9X1V8	Thermotoga maritima	LDO
DEIRA\|EnsemblGenome=DR_1145\|UniProtKB=Q9RV84	Deinococcus radiodurans	LDO
GLOVI\|EnsemblGenome=BAC90704\|UniProtKB=Q7NGX4	Gloeobacter violaceus	LDO
SYNY3\|EnsemblGenome=BAA18871\|UniProtKB=P74751	Synechocystis	LDO
LEPIN\|EnsemblGenome=LA_1888\|UniProtKB=Q8F500	Leptospira interrogans	LDO
BACTN\|EnsemblGenome=BT_0632\|UniProtKB=Q8AA33	Bacteroides thetaiotaomicron	LDO
CHLTR\|EnsemblGenome=CT_064\|UniProtKB=O84067	Chlamydia trachomatis	LDO
RHOBA\|EnsemblGenome=RB1630\|UniProtKB=Q7UX15	Rhodopirellula baltica	O
RHOBA\|EnsemblGenome=RB11673\|UniProtKB=Q7UE01	Rhodopirellula baltica	LDO
AQUAE\|EnsemblGenome=aq_1725\|UniProtKB=O67618	Aquifex aeolicus	LDO
THEYD\|EnsemblGenome=THEYE_A0099\|UniProtKB=B5YHC9	Thermodesulfovibrio yellowstonii	LDO
DICTD\|EnsemblGenome=Dtur_1107\|UniProtKB=B8E2A9	Dictyoglomus turgidum	LDO
FUSNN\|EnsemblGenome=FN0777\|UniProtKB=Q8RFD1	Fusobacterium nucleatum	LDO
HELPY\|EnsemblGenome=HP_0355\|UniProtKB=O25122	Helicobacter pylori	LDO
NEIMB\|EnsemblGenome=NMB0766\|UniProtKB=Q9K055	Neisseria meningitidis serogroup b	LDO
GEOSL\|EnsemblGenome=GSU1266\|UniProtKB=P60789	Geobacter sulfurreducens	LDO
BRADU\|EnsemblGenome=BAC53415\|UniProtKB=Q89BJ8	Bradyrhizobium diazoefficiens	LDO
COXBU\|EnsemblGenome=CBU_1505\|UniProtKB=Q83BK3	Coxiella burnetii	LDO
HAEIN\|EnsemblGenome=HI_0016\|UniProtKB=P43729	Haemophilus influenzae	LDO
SHEON\|Gene_OrderedLocusName=SO_1346\|UniProtKB=Q8EH83	Shewanella oneidensis	LDO
VIBCH\|EnsemblGenome=VC_2463\|UniProtKB=Q9KPB0	Vibrio cholerae	LDO
XANCP\|EnsemblGenome=XCC1270\|UniProtKB=Q8PB55	Xanthomonas campestris	LDO
PSEAE\|EnsemblGenome=PA0767\|UniProtKB=Q9I5G8	Pseudomonas aeruginosa	LDO
SALTY\|EnsemblGenome=STM2583\|UniProtKB=P0A1W4	Salmonella typhimurium	LDO
YERPE\|EnsemblGenome=YP_2520\|UniProtKB=Q8ZD74	Yersinia pestis	LDO
ECOLI\|EnsemblGenome=BAE76745\|UniProtKB=P60785	Escherichia coli	LDO