PANTHER Gene Information

Gene Symbol(s):

ILV2

Organism:

Cryptococcus neoformans

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Gene Name:

Acetolactate synthase, mitochondrial

Gene ID:

CNA02570

Protein ID:

Q5KPJ5

Persistent Id:

PTN001056734

Alternate Ids:

3253594(GeneID)	68052055(GI)
2.2.1.6(EC)	CNA02570(Ensembl)
ILVB_CRYNJ(UniProtKB-ID)	XP_566644(refSeq)
AE017341(EMBL)	AAW40825(Ensembl_TRS)
ILV2(Symbol)	AAW40825(EMBL-CDS)
AAW40825(Ensembl_PRO)	Acetohydroxy-acid synthase(Synonym)
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PANTHER Classification

PANTHER Family:	THIAMINE PYROPHOSPHATE ENZYMES (PTHR18968)
PANTHER Subfamily:	ACETOLACTATE SYNTHASE CATALYTIC SUBUNIT, MITOCHONDRIAL (PTHR18968:SF13)
PANTHER GO-slim Molecular Function:	flavin adenine dinucleotide binding transferase activity
PANTHER GO-slim Biological Process:	branched-chain amino acid biosynthetic process alpha-amino acid biosynthetic process
PANTHER GO-slim Cellular Component:	cytoplasm transferase complex
PANTHER protein class:	ligase

Pathway Categories:

Valine biosynthesis

Acetolactate synthase

Isoleucine biosynthesis

Acetolactate synthase

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	magnesium ion binding, acetolactate synthase activity, thiamine pyrophosphate binding, metal ion binding, flavin adenine dinucleotide binding, transferase activity
GO BP Complete:	isoleucine biosynthetic process, L-valine biosynthetic process, amino acid biosynthetic process, branched-chain amino acid biosynthetic process
GO CC Complete:	mitochondrion, acetolactate synthase complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
YEAST\|SGD=S000004714\|UniProtKB=P07342	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AEL305C\|UniProtKB=Q758Q8	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000198378\|UniProtKB=A0A1D8PJF9	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_C00253g\|UniProtKB=Q6CDI5	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_10808\|UniProtKB=C8V105	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_6G11680\|UniProtKB=Q4WM01	Neosartorya fumigata	O
ASPFU\|EnsemblGenome=AFUA_2G13620\|UniProtKB=Q4X0F8	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU08771\|UniProtKB=F5HBC9	Neurospora crassa	O
SCLS1\|Gene_ORFName=SS1G_08921\|UniProtKB=A7EUB4	Sclerotinia sclerotiorum	O
PHANO\|Gene_ORFName=SNOG_11795\|UniProtKB=Q0U8W9	Phaeosphaeria nodorum	O
PHANO\|EnsemblGenome=SNOG_06095\|UniProtKB=Q0UQ69	Phaeosphaeria nodorum	O
EMENI\|EnsemblGenome=ANIA_04956\|UniProtKB=C8V916	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_3G10310\|UniProtKB=Q4WXQ3	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU07982\|UniProtKB=V5INN6	Neurospora crassa	LDO
SCLS1\|Gene_ORFName=SS1G_06550\|UniProtKB=A7EMK2	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_08152\|UniProtKB=Q0UJB2	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPBP35G2.07\|UniProtKB=P36620	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_03985\|UniProtKB=B6K5L0	Schizosaccharomyces japonicus	LDO
USTMA\|EnsemblGenome=UMAG_03239\|UniProtKB=A0A0D1CPX0	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_04994\|UniProtKB=E3K3I1	Puccinia graminis	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_262880\|UniProtKB=B8C5X8	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_23175\|UniProtKB=B8C663	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3G9J1_PHYRM\|UniProtKB=H3G9J1	Phytophthora ramorum	LDO
GOSHI\|Gene=LOC107943998\|UniProtKB=A0A1U8N620	Gossypium hirsutum	LDO
NITMS\|EnsemblGenome=Nmar_1072\|UniProtKB=A9A4J0	Nitrosopumilus maritimus	LDO
KORCO\|EnsemblGenome=Kcr_0641\|UniProtKB=B1L4L5	Korarchaeum cryptofilum	LDO
SACS2\|EnsemblGenome=SSO1647\|UniProtKB=Q97XR3	Sulfolobus solfataricus	O
SACS2\|EnsemblGenome=SSO2774\|UniProtKB=Q97V62	Sulfolobus solfataricus	O
SACS2\|EnsemblGenome=SSO3210\|UniProtKB=Q97U16	Sulfolobus solfataricus	O
SACS2\|EnsemblGenome=SSO0170\|UniProtKB=Q980V7	Sulfolobus solfataricus	O
SACS2\|EnsemblGenome=SSO0579\|UniProtKB=Q7LXT8	Sulfolobus solfataricus	LDO
PYRAE\|EnsemblGenome=PAE3300\|UniProtKB=Q8ZTD9	Pyrobaculum aerophilum	LDO
METAC\|EnsemblGenome=MA_3792\|UniProtKB=Q8TJJ2	Methanosarcina acetivorans	LDO
METJA\|EnsemblGenome=MJ_0663\|UniProtKB=Q58077	Methanocaldococcus jannaschii	O
METJA\|EnsemblGenome=MJ_0277\|UniProtKB=Q57725	Methanocaldococcus jannaschii	LDO
LEPIN\|EnsemblGenome=LA_0863\|UniProtKB=Q8F7T1	Leptospira interrogans	O
SALTY\|EnsemblGenome=STM3796\|UniProtKB=Q8ZL15	Salmonella typhimurium	O
YERPE\|Gene_OrderedLocusName=YPO2293\|UniProtKB=Q0WEM8	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAE77622\|UniProtKB=P08142	Escherichia coli	O
STRCO\|Gene_OrderedLocusName=SCO2769\|UniProtKB=Q9RDF9	Streptomyces coelicolor	O
MYCTU\|Gene_OrderedLocusName=Rv3470c\|UniProtKB=O06335	Mycobacterium tuberculosis	O
BRADU\|Gene=Q89R07_BRADU\|UniProtKB=Q89R07	Bradyrhizobium diazoefficiens	O
STRCO\|Gene_OrderedLocusName=SCO6201\|UniProtKB=Q9Z5A1	Streptomyces coelicolor	O
BRADU\|Gene=gcl\|UniProtKB=Q89QG2	Bradyrhizobium diazoefficiens	O
PSEAE\|EnsemblGenome=PA1502\|UniProtKB=Q9I3L0	Pseudomonas aeruginosa	O
SALTY\|EnsemblGenome=STM0517\|UniProtKB=Q8ZR85	Salmonella typhimurium	O
ECOLI\|EnsemblGenome=BAE76285\|UniProtKB=P0AEP7	Escherichia coli	O
GLOVI\|Gene=ilvB\|UniProtKB=Q7NGT4	Gloeobacter violaceus	O
BRADU\|Gene=Q89N19_BRADU\|UniProtKB=Q89N19	Bradyrhizobium diazoefficiens	O
VIBCH\|EnsemblGenome=VC_1590\|UniProtKB=Q9KRP6	Vibrio cholerae	O
PSEAE\|EnsemblGenome=PA4180\|UniProtKB=Q9HWK1	Pseudomonas aeruginosa	O
STRCO\|Gene_OrderedLocusName=SCO6975\|UniProtKB=Q8CJL4	Streptomyces coelicolor	O
LISMO\|EnsemblGenome=CAC98465\|UniProtKB=Q8Y9Y1	Listeria monocytogenes	O
BACSU\|EnsemblGenome=BSU_39730\|UniProtKB=P42415	Bacillus subtilis	O
CHLAA\|EnsemblGenome=Caur_2085\|UniProtKB=A9WEY2	Chloroflexus aurantiacus	O
STRCO\|Gene_OrderedLocusName=SCO6584\|UniProtKB=O87839	Streptomyces coelicolor	O
MYCTU\|Gene_OrderedLocusName=Rv1820\|UniProtKB=P9WG39	Mycobacterium tuberculosis	O
CHLAA\|EnsemblGenome=Caur_0163\|UniProtKB=A9WC24	Chloroflexus aurantiacus	LDO
STRCO\|Gene_OrderedLocusName=SCO5512\|UniProtKB=Q9Z567	Streptomyces coelicolor	LDO
MYCTU\|Gene_OrderedLocusName=Rv3003c\|UniProtKB=P9WG41	Mycobacterium tuberculosis	LDO
STRR6\|EnsemblGenome=spr0401\|UniProtKB=Q8DR05	Streptococcus pneumoniae	LDO
STAA8\|EnsemblGenome=SAOUHSC_02282\|UniProtKB=Q2FWK6	Staphylococcus aureus	LDO
LISMO\|Gene=ilvB\|UniProtKB=Q8Y5S1	Listeria monocytogenes	LDO
BACSU\|EnsemblGenome=BSU_28310\|UniProtKB=P37251	Bacillus subtilis	LDO
BACCR\|EnsemblGenome=BC_1777\|UniProtKB=Q81F28	Bacillus cereus	LDO
THEMA\|EnsemblGenome=TM_0548\|UniProtKB=Q9WZ18	Thermotoga maritima	LDO
DEIRA\|EnsemblGenome=DR_1516\|UniProtKB=Q9RU76	Deinococcus radiodurans	LDO
GLOVI\|Gene=ilvG\|UniProtKB=Q7NG94	Gloeobacter violaceus	LDO
LEPIN\|EnsemblGenome=LA_2570\|UniProtKB=Q8F341	Leptospira interrogans	LDO
BACTN\|EnsemblGenome=BT_2077\|UniProtKB=Q8A609	Bacteroides thetaiotaomicron	LDO
RHOBA\|EnsemblGenome=RB12905\|UniProtKB=Q7UHW9	Rhodopirellula baltica	LDO
AQUAE\|EnsemblGenome=aq_451\|UniProtKB=O66759	Aquifex aeolicus	LDO
THEYD\|EnsemblGenome=THEYE_A1275\|UniProtKB=B5YFP1	Thermodesulfovibrio yellowstonii	LDO
DICTD\|EnsemblGenome=Dtur_1187\|UniProtKB=B8E2W6	Dictyoglomus turgidum	LDO
BRADU\|Gene=iivG\|UniProtKB=Q89F88	Bradyrhizobium diazoefficiens	O
PSEAE\|EnsemblGenome=PA2035\|UniProtKB=Q9I280	Pseudomonas aeruginosa	O
NEIMB\|EnsemblGenome=NMB1577\|UniProtKB=Q9JYI0	Neisseria meningitidis serogroup b	LDO
GEOSL\|EnsemblGenome=GSU1911\|UniProtKB=Q3V8C8	Geobacter sulfurreducens	LDO
BRADU\|Gene=Q89QL7_BRADU\|UniProtKB=Q89QL7	Bradyrhizobium diazoefficiens	O
BRADU\|Gene=ilvI\|UniProtKB=Q89G44	Bradyrhizobium diazoefficiens	LDO
SHEON\|Gene_OrderedLocusName=SO_3262\|UniProtKB=Q8EC82	Shewanella oneidensis	O
SHEON\|Gene_OrderedLocusName=SO_4347\|UniProtKB=Q8E9D7	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_0031\|UniProtKB=Q9KVV7	Vibrio cholerae	O
XANCP\|EnsemblGenome=XCC3324\|UniProtKB=Q8P5L4	Xanthomonas campestris	O
SALTY\|EnsemblGenome=STM3901\|UniProtKB=Q9L6T2	Salmonella typhimurium	O
YERPE\|Gene_OrderedLocusName=YPO3901\|UniProtKB=A0A5P8YAV0	Yersinia pestis	O
HAEIN\|EnsemblGenome=HI_1585\|UniProtKB=P45261	Haemophilus influenzae	LDO
SHEON\|Gene_OrderedLocusName=SO_2279\|UniProtKB=Q8EET7	Shewanella oneidensis	LDO
VIBCH\|EnsemblGenome=VC_2483\|UniProtKB=Q9KP90	Vibrio cholerae	LDO
PSEAE\|EnsemblGenome=PA3506\|UniProtKB=Q9HYA3	Pseudomonas aeruginosa	O
PSEAE\|EnsemblGenome=PA4977\|UniProtKB=Q9HUI8	Pseudomonas aeruginosa	O
PSEAE\|EnsemblGenome=PA1417\|UniProtKB=Q9I3S7	Pseudomonas aeruginosa	O
PSEAE\|EnsemblGenome=PA4696\|UniProtKB=Q9HVA0	Pseudomonas aeruginosa	LDO
SALTY\|EnsemblGenome=STM0116\|UniProtKB=P40811	Salmonella typhimurium	LDO
YERPE\|Gene_OrderedLocusName=YPO0539\|UniProtKB=A0A380PN24	Yersinia pestis	LDO
ECOLI\|EnsemblGenome=BAB96646\|UniProtKB=P00893	Escherichia coli	LDO