PANTHER Gene Information

Gene Symbol(s):

CNF04610

Organism:

Cryptococcus neoformans

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Gene Name:

D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding domain-containing protein

Gene ID:

CNF04610

Protein ID:

Q5KEQ8

Persistent Id:

PTN000864046

Alternate Ids:

Q5KEQ8_CRYNJ(UniProtKB-ID)	AAW44117(EMBL-CDS)
58268536(GI)	XP_571424(refSeq)
AE017346(EMBL)	CNF04610(Ensembl)
Q5KEQ8(Synonym)
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PANTHER Classification

PANTHER Family:	2-HYDROXYACID DEHYDROGENASE-RELATED (PTHR10996)
PANTHER Subfamily:	2-HYDROXYACID DEHYDROGENASE (PTHR10996:SF289)
PANTHER GO-slim Molecular Function:	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	cytosol
PANTHER protein class:	dehydrogenase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	oxidoreductase activity, NAD binding, hydroxypyruvate reductase [NAD(P)H] activity, glyoxylate reductase (NADPH) activity
GO BP Complete:	-
GO CC Complete:	cytosol

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
BOVIN\|Ensembl=ENSBTAG00000036298.3\|UniProtKB=G3N069	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000038475.3\|UniProtKB=A0A4X1SD82	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000007419.4\|UniProtKB=F7DI43	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000027544.4\|UniProtKB=M3X5F0	Felis catus	O
MONDO\|Ensembl=ENSMODG00000011943.4\|UniProtKB=F7DDZ3	Monodelphis domestica	O
CHICK\|Ensembl=ENSGALG00010008097.1\|UniProtKB=A0A8V0Y432	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000028770.2\|UniProtKB=R4G9F0	Anolis carolinensis	O
CHICK\|Ensembl=ENSGALG00010008145.1\|UniProtKB=A0A8V0Y4H3	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000029150.2\|UniProtKB=R4GD30	Anolis carolinensis	O
CHICK\|Ensembl=ENSGALG00010008091.1\|UniProtKB=A0A8V0XXV3	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000001320.4\|UniProtKB=G1K997	Anolis carolinensis	O
XENTR\|Ensembl=ENSXETG00000033100\|UniProtKB=A0A6I8PWL3	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000018163.2\|UniProtKB=H2MVB6	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000002851.2\|UniProtKB=H2LCC2	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-060512-216\|UniProtKB=F1QW85	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000008362.1\|UniProtKB=W5MP45	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000001383.3\|UniProtKB=F6S8Y1	Ciona intestinalis	O
BRAFL\|Gene=LOC118409767\|UniProtKB=A0A9J7MH19	Branchiostoma floridae	O
BRAFL\|Gene=LOC118406319\|UniProtKB=A0A9J7KJB0	Branchiostoma floridae	O
BRAFL\|Gene=LOC118417596\|UniProtKB=A0A9J7MTA2	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC105446694\|UniProtKB=A0A7M7N453	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC574587\|UniProtKB=A0A7M7RBJ7	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC592714\|UniProtKB=A0A7M7T1Z8	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC585161\|UniProtKB=A0A7M7HIY2	Strongylocentrotus purpuratus	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g174268\|UniProtKB=A7STU0	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g131545\|UniProtKB=A7STU2	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g99162\|UniProtKB=A7RZX5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g150576\|UniProtKB=A7T8U8	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG30178\|UniProtKB=B3S6L4	Trichoplax adhaerens	O
YEAST\|SGD=S000005218\|UniProtKB=P53839	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AFR675W\|UniProtKB=Q752A0	Eremothecium gossypii	O
CANAL\|CGD=CAL0000192040\|UniProtKB=A0A1D8PCW3	Candida albicans	O
CANAL\|CGD=CAL0000175900\|UniProtKB=Q59SC0	Candida albicans	O
CANAL\|CGD=CAL0000200856\|UniProtKB=A0A1D8PI81	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_B21670g\|UniProtKB=Q6CDS0	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_D25256g\|UniProtKB=Q6C7U5	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_07934\|UniProtKB=C8V569	Emericella nidulans	O
EMENI\|EnsemblGenome=ANIA_07663\|UniProtKB=Q5AVL7	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_2G01280\|UniProtKB=Q4WIM9	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU01078\|UniProtKB=Q1K894	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_01480\|UniProtKB=A7E852	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_00465\|UniProtKB=Q0V699	Phaeosphaeria nodorum	O
PHANO\|Gene_ORFName=SNOG_08793\|UniProtKB=Q0UHH1	Phaeosphaeria nodorum	O
PHANO\|EnsemblGenome=SNOG_15447\|UniProtKB=Q0TYA3	Phaeosphaeria nodorum	O
EMENI\|EnsemblGenome=ANIA_00775\|UniProtKB=Q5BFA5	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_1G14400\|UniProtKB=E9RDD2	Neosartorya fumigata	O
PHANO\|EnsemblGenome=SNOG_14880\|UniProtKB=Q0U027	Phaeosphaeria nodorum	O
EMENI\|EnsemblGenome=ANIA_01563\|UniProtKB=C8VN03	Emericella nidulans	O
NEUCR\|EnsemblGenome=NCU05050\|UniProtKB=Q7RXD4	Neurospora crassa	O
NEUCR\|EnsemblGenome=NCU04857\|UniProtKB=Q7S388	Neurospora crassa	O
PHANO\|EnsemblGenome=SNOG_04368\|UniProtKB=Q0UV46	Phaeosphaeria nodorum	O
EMENI\|EnsemblGenome=ANIA_05030\|UniProtKB=Q5B350	Emericella nidulans	O
EMENI\|EnsemblGenome=ANIA_05534\|UniProtKB=Q5B1P6	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_4G11840\|UniProtKB=Q4WQ76	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU07931\|UniProtKB=Q7S9Y7	Neurospora crassa	O
PHANO\|EnsemblGenome=SNOG_01845\|UniProtKB=Q0V2B9	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPACUNK4.10\|UniProtKB=O14075	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_00281\|UniProtKB=B6JV76	Schizosaccharomyces japonicus	O
SCHJY\|EnsemblGenome=SJAG_01432\|UniProtKB=B6JXX0	Schizosaccharomyces japonicus	O
USTMA\|EnsemblGenome=UMAG_11323\|UniProtKB=A0A0D1EAT7	Ustilago maydis	O
DICDI\|dictyBase=DDB_G0292104\|UniProtKB=Q54DP1	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_147384\|UniProtKB=F0Z8D3	Dictyostelium purpureum	O
DICPU\|EnsemblGenome=DICPUDRAFT_52429\|UniProtKB=F0Z8B1	Dictyostelium purpureum	O
DICPU\|EnsemblGenome=DICPUDRAFT_44248\|UniProtKB=F1A5T1	Dictyostelium purpureum	O
DICPU\|EnsemblGenome=DICPUDRAFT_147361\|UniProtKB=F0Z8B2	Dictyostelium purpureum	O
TRIV3\|Gene_ORFName=TVAG_047210\|UniProtKB=A2FHI8	Trichomonas vaginalis	O
PHYRM\|Gene=H3GAI8_PHYRM\|UniProtKB=H3GAI8	Phytophthora ramorum	O
PHYRM\|Gene=H3G4Z8_PHYRM\|UniProtKB=H3G4Z8	Phytophthora ramorum	O
PHYRM\|Gene=H3GAI7_PHYRM\|UniProtKB=H3GAI7	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_06g295450v5\|UniProtKB=A8IPI7	Chlamydomonas reinhardtii	O
AMBTC\|EnsemblGenome=AMTR_s00152p00085890\|UniProtKB=W1PLF0	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_1G03130\|UniProtKB=A0A0K9PQ30	Zostera marina	O
MUSAM\|EnsemblGenome=Ma05_g21330\|UniProtKB=A0A804J6X6	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_017480mg\|UniProtKB=K3YT85	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3004G001300\|UniProtKB=A0A194YLZ3	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb229250\|UniProtKB=A0A804PE80	Zea mays	O
ORYSJ\|EnsemblGenome=Os02g0101500\|UniProtKB=Q6YU90	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_3g00330v3\|UniProtKB=A0A0Q3J335	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0538240\|UniProtKB=F2D8L5	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS6A02G000400\|UniProtKB=A0A3B6NGZ5	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6B02G004400\|UniProtKB=A0A341WSR4	Triticum aestivum	O
NELNU\|Gene=LOC104603640\|UniProtKB=A0A1U8ASF7	Nelumbo nucifera	O
SPIOL\|Gene=LOC110791537\|UniProtKB=A0A9R0JYM8	Spinacia oleracea	O
HELAN\|EnsemblGenome=HanXRQr2_Chr17g0794251\|UniProtKB=A0A251RND2	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C300120290\|UniProtKB=A0A9R1W2A7	Lactuca sativa	O
CAPAN\|EnsemblGenome=T459_32433\|UniProtKB=A0A2G2Y1W6	Capsicum annuum	O
CAPAN\|EnsemblGenome=T459_16888\|UniProtKB=A0A2G2Z9Z9	Capsicum annuum	O
CAPAN\|EnsemblGenome=T459_18953\|UniProtKB=A0A2G2Z0K8	Capsicum annuum	O
CAPAN\|EnsemblGenome=T459_14966\|UniProtKB=A0A2G2ZJ49	Capsicum annuum	O
CAPAN\|EnsemblGenome=T459_32155\|UniProtKB=A0A2G2Y2U0	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400006186\|UniProtKB=M1A6N6	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc01g111630.3\|UniProtKB=A0A3Q7EUQ6	Solanum lycopersicum	O
TOBAC\|Gene=LOC107765918\|UniProtKB=A0A1S3XJF2	Nicotiana tabacum	O
TOBAC\|Gene=LOC107805344\|UniProtKB=A0A1S4B7M2	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi03g00154\|UniProtKB=D7U543	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_I01423\|UniProtKB=A0A059ANX4	Eucalyptus grandis	O
BRANA\|Gene_ORFName=GSBRNA2T00124391001\|UniProtKB=A0A078EZ90	Brassica napus	O
BRACM\|EnsemblGenome=Bra004275\|UniProtKB=M4CJ91	Brassica campestris	O
BRACM\|EnsemblGenome=Bra004055\|UniProtKB=M4CIM1	Brassica campestris	O
ARATH\|TAIR=locus=2200231\|UniProtKB=Q9C9W5	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107921219\|UniProtKB=A0A1U8KVZ3	Gossypium hirsutum	O
GOSHI\|Gene=LOC107947132\|UniProtKB=A0A1U8NDT3	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_006612\|UniProtKB=A0A061E001	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g015895mg\|UniProtKB=A0A067FXZ6	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_004G175800v3\|UniProtKB=A0A2K2AW94	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_04G076300\|UniProtKB=A0A2C9W0M5	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_1112510\|UniProtKB=B9T0F2	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_20G107800\|UniProtKB=Q84L66	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_10G281400\|UniProtKB=B0M1A3	Glycine max	O
MEDTR\|EnsemblGenome=MTR_1g112510\|UniProtKB=A0A072VRS6	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr13_09150\|UniProtKB=A0A2I4EWU8	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_7G012940\|UniProtKB=A0A0A0K5Z2	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_8G166000\|UniProtKB=A0A251MYV6	Prunus persica	O
PRUPE\|EnsemblGenome=PRUPE_7G264000\|UniProtKB=M5W8G7	Prunus persica	O
PHYPA\|EnsemblGenome=Pp3c18_12500\|UniProtKB=A9RE03	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c19_20080\|UniProtKB=A9U188	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0015s0044\|UniProtKB=A0A2R6XGJ7	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_001860030\|UniProtKB=A0A1Y1I6K8	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_001580030\|UniProtKB=A0A1Y1I2N3	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_000030590\|UniProtKB=A0A1Y1HIT3	Klebsormidium nitens	O
SACS2\|EnsemblGenome=SSO3187\|UniProtKB=Q97U35	Sulfolobus solfataricus	O
PYRAE\|EnsemblGenome=PAE1175\|UniProtKB=Q8ZXP5	Pyrobaculum aerophilum	O
STRCO\|Gene_OrderedLocusName=SCO0348\|UniProtKB=Q9RJW2	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO7119\|UniProtKB=Q9FC67	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO0663\|UniProtKB=Q9RJA1	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO5510\|UniProtKB=Q9Z569	Streptomyces coelicolor	O
DEIRA\|EnsemblGenome=DR_1701\|UniProtKB=Q9RTQ5	Deinococcus radiodurans	O
CHLAA\|EnsemblGenome=Caur_0825\|UniProtKB=A9WGW6	Chloroflexus aurantiacus	O
STRCO\|Gene_OrderedLocusName=SCO2824\|UniProtKB=Q93J73	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO3478\|UniProtKB=Q9RKF9	Streptomyces coelicolor	O
CLOBH\|Gene_OrderedLocusName=CBO3593\|UniProtKB=A5I7W7	Clostridium botulinum	O
STAA8\|EnsemblGenome=SAOUHSC_01998\|UniProtKB=Q2G281	Staphylococcus aureus	O
STAA8\|EnsemblGenome=SAOUHSC_00866\|UniProtKB=Q2FZW9	Staphylococcus aureus	O
BACSU\|EnsemblGenome=BSU_34680\|UniProtKB=O32264	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_4903\|UniProtKB=Q816F6	Bacillus cereus	O
GLOVI\|Gene=Q7NEV2_GLOVI\|UniProtKB=Q7NEV2	Gloeobacter violaceus	O
SYNY3\|Gene=P73990_SYNY3\|UniProtKB=P73990	Synechocystis	O
LEPIN\|EnsemblGenome=LA_1629\|UniProtKB=Q8F5N8	Leptospira interrogans	O
RHOBA\|EnsemblGenome=RB10004\|UniProtKB=Q7UKR1	Rhodopirellula baltica	O
DICTD\|EnsemblGenome=Dtur_1692\|UniProtKB=B8E390	Dictyoglomus turgidum	O
BRADU\|Gene=Q89EL0_BRADU\|UniProtKB=Q89EL0	Bradyrhizobium diazoefficiens	O
BRADU\|Gene=Q89WC5_BRADU\|UniProtKB=Q89WC5	Bradyrhizobium diazoefficiens	O
XANCP\|EnsemblGenome=XCC2550\|UniProtKB=Q8P7R1	Xanthomonas campestris	O
PSEAE\|EnsemblGenome=PA3896\|UniProtKB=Q9HXB7	Pseudomonas aeruginosa	O
PSEAE\|EnsemblGenome=PA2263\|UniProtKB=Q9I1L0	Pseudomonas aeruginosa	O
SALTY\|EnsemblGenome=STM3646\|UniProtKB=Q8ZLA1	Salmonella typhimurium	O
YERPE\|Gene_OrderedLocusName=YPO2536\|UniProtKB=A0A3N4B3L9	Yersinia pestis	O
YERPE\|Gene_OrderedLocusName=YPO1288\|UniProtKB=A0A3N4B378	Yersinia pestis	O
YERPE\|EnsemblGenome=YP_3988\|UniProtKB=Q0W9V5	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAE77742\|UniProtKB=P37666	Escherichia coli	O