PANTHER Gene Information

Gene Symbol(s):

dlk2

Organism:

Danio rerio

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Gene Name:

Protein delta homolog 2 isoform X1

Gene ID:

dlk2

Protein ID:

A0A8M9PYA6

Persistent Id:

PTN001234843

Alternate Ids:

688581776(GI)	A0A8M9PYA6_DANRE(UniProtKB-ID)
100150992(GeneID)	A0A8M9PYA6(Synonym)
XP_001921712(refSeq)
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PANTHER Classification

PANTHER Family:	NOTCH LIGAND FAMILY MEMBER (PTHR24044)
PANTHER Subfamily:	PROTEIN DELTA HOMOLOG 2 (PTHR24044:SF423)
PANTHER GO-slim Molecular Function:	signaling receptor binding
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	intercellular signal molecule

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	calcium ion binding, Notch binding
GO BP Complete:	negative regulation of angiogenesis, vasculature development, negative regulation of Notch signaling pathway
GO CC Complete:	membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=21113\|UniProtKB=Q6UY11	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000018198.5\|UniProtKB=A0A2J8P076	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000008606.3\|UniProtKB=G3QZU4	Gorilla gorilla gorilla	LDO
MOUSE\|MGI=MGI=2146838\|UniProtKB=Q8K1E3	Mus musculus	LDO
RAT\|RGD=1309143\|UniProtKB=D3ZUK3	Rattus norvegicus	LDO
PIG\|Ensembl=ENSSSCG00000001682\|UniProtKB=B2LW77	Sus scrofa	LDO
FELCA\|Ensembl=ENSFCAG00000030746.4\|UniProtKB=M3X710	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000018972.3\|UniProtKB=F7FPK7	Monodelphis domestica	LDO
CHICK\|Ensembl=ENSGALG00010007626.1\|UniProtKB=A0A8V0XTH5	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000038792.1\|UniProtKB=A0A803T220	Anolis carolinensis	LDO
XENLA\|Gene=dlk2.S\|UniProtKB=A0A1L8G115	Xenopus laevis	O
XENLA\|Gene=dlk2.L\|UniProtKB=A0A1L8G6Q3	Xenopus laevis	LDO
ORYLA\|Ensembl=ENSORLG00000003193.2\|UniProtKB=H2LDG7	Oryzias latipes	LDO
LEPOC\|Ensembl=ENSLOCG00000016721.1\|UniProtKB=W5NJ49	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000008346.3\|UniProtKB=F7B426	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000024431.1\|UniProtKB=H2XU21	Ciona intestinalis	O
BRAFL\|Gene=LOC118428620\|UniProtKB=A0A9J7M533	Branchiostoma floridae	O
BRAFL\|Gene=LOC118422258\|UniProtKB=A0A9J7N0L8	Branchiostoma floridae	O
BRAFL\|Gene=LOC118421069\|UniProtKB=A0A9J7LLQ5	Branchiostoma floridae	O
BRAFL\|Gene=LOC118431392\|UniProtKB=A0A9J7MCP4	Branchiostoma floridae	O
BRAFL\|Gene=LOC118421797\|UniProtKB=A0A9J7MYW5	Branchiostoma floridae	O
BRAFL\|Gene=LOC118405716\|UniProtKB=A0A9J7HNS8	Branchiostoma floridae	O
BRAFL\|Gene=LOC118423048\|UniProtKB=A0A9J7LR65	Branchiostoma floridae	O
BRAFL\|Gene=LOC118420675\|UniProtKB=A0A9J7MYL1	Branchiostoma floridae	O
BRAFL\|Gene=LOC118427638\|UniProtKB=A0A9J7N867	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC115919802\|UniProtKB=A0A7M7N1Y9	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105436828\|UniProtKB=A0A7M7NMR7	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115921201\|UniProtKB=A0A7M7NC56	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC587522\|UniProtKB=A0A7M7PT58	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100888711\|UniProtKB=A0A7M7PU58	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105439527\|UniProtKB=A0A7M7MZY7	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC575916\|UniProtKB=A0A7M7RA06	Strongylocentrotus purpuratus	O
CAEBR\|Gene_ORFName=CBG07577\|UniProtKB=A8X4I7	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00095695\|UniProtKB=A0A2A6BJE3	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00020806\|UniProtKB=Q23046	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG19009\|UniProtKB=A8XUK1	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00019957\|UniProtKB=Q21850	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG14646\|UniProtKB=A8XKD0	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00001148\|UniProtKB=Q9NL29	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00010134\|UniProtKB=P90891	Caenorhabditis elegans	O
PRIPA\|EnsemblGenome=WBGene00273091\|UniProtKB=A0A2A6C8I8	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0051665\|UniProtKB=Q7KU08	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP010049\|UniProtKB=A0A1S4H2U6	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC031158\|UniProtKB=A0A139WHZ4	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC031831\|UniProtKB=A0A139WA83	Tribolium castaneum	O
DAPPU\|Gene_ORFName=DAPPUDRAFT_104541\|UniProtKB=E9GMK5	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_308094\|UniProtKB=E9H693	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW011066\|UniProtKB=B7Q438	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG158374\|UniProtKB=T1EMQ2	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG192336\|UniProtKB=T1FTU2	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG88449\|UniProtKB=T1G727	helobdella robusta	O
TRIAD\|EnsemblGenome=TriadG55384\|UniProtKB=B3RUR5	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG61951\|UniProtKB=B3SCF3	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG62176\|UniProtKB=B3SD19	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG64025\|UniProtKB=B3RZW1	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG57305\|UniProtKB=B3RZ28	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG587\|UniProtKB=B3S6K5	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_38707\|UniProtKB=A9V9N1	Monosiga brevicollis	O
GIAIC\|EnsemblGenome=GL50803_24512\|UniProtKB=A8B4D5	Giardia intestinalis	O
CHLRE\|EnsemblGenome=CHLRE_16g690095v5\|UniProtKB=A0A2K3CW78	Chlamydomonas reinhardtii	O