PANTHER Gene Information

Gene Symbol(s):

hnf4a

Organism:

Danio rerio

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Gene Name:

Hepatocyte nuclear factor 4-alpha isoform X3

Gene ID:

hnf4a

Protein ID:

A0A8M9PEX6

Persistent Id:

PTN000639227

Alternate Ids:

A0A8M9PEX6_DANRE(UniProtKB-ID)	A0A8M9PEX6(Synonym)
XM_021469748(refSeq)
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PANTHER Classification

PANTHER Family:	NUCLEAR HORMONE RECEPTOR (PTHR24083)
PANTHER Subfamily:	HEPATOCYTE NUCLEAR FACTOR 4-ALPHA (PTHR24083:SF41)
PANTHER GO-slim Molecular Function:	signaling receptor activity RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific
PANTHER GO-slim Biological Process:	positive regulation of transcription by RNA polymerase II anatomical structure development cell differentiation
PANTHER GO-slim Cellular Component:
PANTHER protein class:	C4 zinc finger nuclear receptor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	DNA binding, DNA-binding transcription factor activity, zinc ion binding, nuclear receptor activity, metal ion binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, sequence-specific DNA binding
GO BP Complete:	response to bacterium, pancreas regeneration, cell differentiation, regulation of DNA-templated transcription, positive regulation of transcription by RNA polymerase II, endocrine pancreas development, type B pancreatic cell development
GO CC Complete:	nucleus

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=5024\|UniProtKB=P41235	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000013519.7\|UniProtKB=A0A2I3TE66	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000006988.4\|UniProtKB=G3QVQ9	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000006464.4\|UniProtKB=F7HBP3	Macaca mulatta	LDO
MOUSE\|MGI=MGI=109128\|UniProtKB=P49698	Mus musculus	LDO
RAT\|RGD=2810\|UniProtKB=P22449	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000012116.6\|UniProtKB=Q7YRQ5	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000007371.5\|UniProtKB=A0A288CG37	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000024450.4\|UniProtKB=A0A5F5PJZ1	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000008178.6\|UniProtKB=M3W941	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845013683.1\|UniProtKB=A0A8I3NQX7	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000016216.4\|UniProtKB=A0A5F8GKY8	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000006363.3\|UniProtKB=F6Q8N6	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010024342.1\|UniProtKB=F1NZ15	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000016803.4\|UniProtKB=A0A803TVH7	Anolis carolinensis	LDO
XENLA\|Gene=hnf4a\|UniProtKB=Q91766	Xenopus laevis	O
XENLA\|Gene=hnf4a.S\|UniProtKB=A0A8J1LW19	Xenopus laevis	O
XENLA\|Gene=LOC108700876\|UniProtKB=A0A1L8ESM4	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-482419\|UniProtKB=A0A6I8RHJ3	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000016380.2\|UniProtKB=A0A3B3H536	Oryzias latipes	LDO
LEPOC\|Ensembl=ENSLOCG00000001957.1\|UniProtKB=W5M1L6	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000009566.3\|UniProtKB=Q4H3D5	Ciona intestinalis	O
BRAFL\|Gene=LOC118417620\|UniProtKB=A0A9J7LAA7	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC574894\|UniProtKB=A0A7M7HM16	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00003637\|UniProtKB=Q17370	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG09380\|UniProtKB=A8X982	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00115240\|UniProtKB=A0A2A6CA98	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00003727\|UniProtKB=B3WFU1	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG10861\|UniProtKB=A8XC57	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00003639\|UniProtKB=O45666	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00026621\|UniProtKB=A8WWW4	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00100746\|UniProtKB=A0A8R1U9E8	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00003616\|UniProtKB=Q17589	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00042514\|UniProtKB=A8WKL6	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG00093\|UniProtKB=A8WMA2	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00105928\|UniProtKB=A0A2A6CP09	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00109750\|UniProtKB=A0A2A6B4X8	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00003630\|UniProtKB=Q22127	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00025207\|UniProtKB=A8WRX9	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00111556\|UniProtKB=A0A2A6BC28	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00003708\|UniProtKB=O16890	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00003690\|UniProtKB=O17611	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00035358\|UniProtKB=A8XL63	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00003628\|UniProtKB=Q17771	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00034961\|UniProtKB=A8XK15	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00096534\|UniProtKB=A0A2A6CF52	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00011100\|UniProtKB=Q21806	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG23379\|UniProtKB=A8Y422	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00015396\|UniProtKB=O01446	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00015397\|UniProtKB=A0A131MB42	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00003706\|UniProtKB=G5EE21	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00003719\|UniProtKB=A5JYV4	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00015395\|UniProtKB=O01448	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00003650\|UniProtKB=O17898	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG01262\|UniProtKB=A8WPZ4	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG22907\|UniProtKB=A8Y3C1	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00003726\|UniProtKB=O01930	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG23383\|UniProtKB=A8Y419	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00007546\|UniProtKB=O01929	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG23381\|UniProtKB=A8Y420	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00011099\|UniProtKB=Q21805	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00011098\|UniProtKB=Q21804	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00011097\|UniProtKB=Q21803	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00007547\|UniProtKB=O01931	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG01321\|UniProtKB=A8WQ49	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG10507\|UniProtKB=A8XAY8	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00041746\|UniProtKB=A8Y421	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00017198\|UniProtKB=Q19155	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG19242\|UniProtKB=A8XV60	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00019816\|UniProtKB=A0A0K3AVS8	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG26996\|UniProtKB=B6IIF3	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00017787\|UniProtKB=H2KYV4	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00008221\|UniProtKB=P91983	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG06732\|UniProtKB=A8X2Z0	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG06740\|UniProtKB=A8X2Z5	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00015705\|UniProtKB=Q17929	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00003683\|UniProtKB=A0A131MBQ7	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00020748\|UniProtKB=O61939	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG06731\|UniProtKB=A8X2Y9	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00016975\|UniProtKB=Q18895	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00032122\|UniProtKB=A8XC56	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00119151\|UniProtKB=A0A2A6CLW3	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00279341\|UniProtKB=A0A2A6CKC2	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00203758\|UniProtKB=A0A2A6CM83	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00090068\|UniProtKB=A0A2A6BG15	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00276740\|UniProtKB=A0A2A6CFG0	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00280862\|UniProtKB=A0A2A6D1W4	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00278813\|UniProtKB=A0A2A6C265	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00278946\|UniProtKB=A0A2A6C203	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00096415\|UniProtKB=A0A2A6BDA5	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00115846\|UniProtKB=A0A2A6BG79	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00097940\|UniProtKB=A0A2A6BB92	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00091968\|UniProtKB=A0A2A6BQ02	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00277325\|UniProtKB=A0A2A6BCE6	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00119102\|UniProtKB=A0A2A6CLE1	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00279909\|UniProtKB=A0A2A6CQH8	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00116568\|UniProtKB=A0A2A6CKH9	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00097935\|UniProtKB=A0A2A6BBI6	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00278728\|UniProtKB=A0A2A6C415	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00098478\|UniProtKB=A0A2A6D152	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00275433\|UniProtKB=A0A2A6BF23	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00116648\|UniProtKB=A0A2A6CP14	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00206029\|UniProtKB=A0A2A6CNZ0	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00279621\|UniProtKB=A0A2A6CJ74	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00110262\|UniProtKB=A0A2A6D254	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00110391\|UniProtKB=A0A2A6D2R1	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00277526\|UniProtKB=A0A2A6CTH8	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00113282\|UniProtKB=A0A2A6BEN6	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00272098\|UniProtKB=A0A2A6BPC0	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00281389\|UniProtKB=A0A2A6B351	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00204953\|UniProtKB=A0A2A6CFE8	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00089946\|UniProtKB=A0A2A6BF96	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00116647\|UniProtKB=A0A2A6CNZ3	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00305089\|UniProtKB=A0A8R1Z3K2	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00108782\|UniProtKB=A0A8R1YCU5	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00304862\|UniProtKB=A0A8R1V3G6	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00305051\|UniProtKB=A0A8R1V6J4	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00305052\|UniProtKB=A0A8R1V5Z8	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00091860\|UniProtKB=A0A8R1Y5U6	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00279119\|UniProtKB=A0A2A6C320	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00003704\|UniProtKB=G5EEM0	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00024680\|UniProtKB=A8WQF2	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00003691\|UniProtKB=Q95ZS3	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00041693\|UniProtKB=A8Y474	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00003658\|UniProtKB=Q9XXM8	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00040230\|UniProtKB=A8Y041	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00041692\|UniProtKB=A8Y475	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00003609\|UniProtKB=P41999	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00036487\|UniProtKB=A8XPJ5	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00091334\|UniProtKB=A0A2A6CIJ7	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00003710\|UniProtKB=G5EET0	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG10855\|UniProtKB=A8XC54	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00282778\|UniProtKB=A0A2A6BG44	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00100400\|UniProtKB=A0A2A6CZK3	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00003613\|UniProtKB=O02151	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00041261\|UniProtKB=A8Y2V6	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00096533\|UniProtKB=A0A2A6B4L3	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00015497\|UniProtKB=Q65CM0	Caenorhabditis elegans	O
PRIPA\|EnsemblGenome=WBGene00281113\|UniProtKB=A0A2A6BVS0	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00003654\|UniProtKB=O44960	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG04204\|UniProtKB=A8WWF1	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00003659\|UniProtKB=P91829	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00026623\|UniProtKB=A8WWW7	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00282340\|UniProtKB=A0A2A6BM72	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0004914\|UniProtKB=P49866	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP002155\|UniProtKB=Q7PTL7	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC008726\|UniProtKB=A0A139WFI4	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_59378\|UniProtKB=E9H7Y7	Daphnia pulex	O
HELRO\|EnsemblGenome=HelroG67417\|UniProtKB=T1FZ05	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG68918\|UniProtKB=T1FZL4	helobdella robusta	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g89471\|UniProtKB=A7RQ27	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG50786\|UniProtKB=B3S6R0	Trichoplax adhaerens	O