PANTHER Gene Information

Gene Symbol(s):

pde3a

Organism:

Danio rerio

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Gene Name:

Phosphodiesterase

Gene ID:

pde3a

Protein ID:

A0A8M3B8Q1

Persistent Id:

PTN000886736

Alternate Ids:

A0A8M3B8Q1(Synonym)	567051(GeneID)
XP_009298269(refSeq)	A0A8M3B8Q1_DANRE(UniProtKB-ID)
688546065(GI)
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PANTHER Classification

PANTHER Family:	CYCLIC NUCLEOTIDE PHOSPHODIESTERASE (PTHR11347)
PANTHER Subfamily:	PHOSPHODIESTERASE (PTHR11347:SF104)
PANTHER GO-slim Molecular Function:	cyclic-nucleotide phosphodiesterase activity
PANTHER GO-slim Biological Process:	cAMP-mediated signaling
PANTHER GO-slim Cellular Component:	cytosol
PANTHER protein class:	phosphodiesterase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	metal ion binding, 3',5'-cyclic-GMP phosphodiesterase activity, phosphoric diester hydrolase activity, 3',5'-cyclic-AMP phosphodiesterase activity, 3',5'-cyclic-nucleotide phosphodiesterase activity, hydrolase activity
GO BP Complete:	signal transduction, cAMP-mediated signaling
GO CC Complete:	membrane, cytosol

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=8778\|UniProtKB=Q14432	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000004748.5\|UniProtKB=H2R265	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000013706.3\|UniProtKB=G3RCY0	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000008269.4\|UniProtKB=F7HBP7	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1860764\|UniProtKB=Q9Z0X4	Mus musculus	LDO
RAT\|RGD=61942\|UniProtKB=Q62865	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000017260.7\|UniProtKB=A0A3Q1M1E8	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000028662.4\|UniProtKB=I3L6S5	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000016360.4\|UniProtKB=A0A3Q2GSQ9	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000000972.6\|UniProtKB=M3VVR5	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845015831.1\|UniProtKB=A0A8I3NYE0	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000017859.5\|UniProtKB=F6YIK3	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000032057.2\|UniProtKB=A0A6I8NMM6	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010011688.1\|UniProtKB=A0A8V0YC57	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000017514.4\|UniProtKB=G1KU23	Anolis carolinensis	LDO
XENLA\|Gene=pde3a.L\|UniProtKB=A0A8J1MJX0	Xenopus laevis	O
XENLA\|Gene=LOC108712511\|UniProtKB=A0A8J1MPU3	Xenopus laevis	LDO
XENTR\|Gene=pde3a\|UniProtKB=A0A8J1J7W0	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000008246.2\|UniProtKB=H2LW64	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000004498.2\|UniProtKB=H2LI30	Oryzias latipes	LDO
LEPOC\|Ensembl=ENSLOCG00000015415.1\|UniProtKB=W5NEB5	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000005633.3\|UniProtKB=F7A9J1	Ciona intestinalis	O
BRAFL\|Gene=LOC118406636\|UniProtKB=A0A9J7HND5	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC589178\|UniProtKB=A0A7M7T005	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00008443\|UniProtKB=Q8I0P7	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG20885\|UniProtKB=A8XYV6	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00111879\|UniProtKB=A0A2A6CX52	Pristionchus pacificus	O
IXOSC\|EnsemblGenome=ISCW006877\|UniProtKB=B7PL40	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG114833\|UniProtKB=T1EG47	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG191746\|UniProtKB=T1FT94	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g97137\|UniProtKB=A7RXZ4	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG22319\|UniProtKB=B3RSH4	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_24275\|UniProtKB=A9UVX6	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_34427\|UniProtKB=A9VBQ1	Monosiga brevicollis	O
YEAST\|SGD=S000005887\|UniProtKB=P06776	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ADR395C\|UniProtKB=Q758Y3	Eremothecium gossypii	O
CANAL\|CGD=CAL0000178266\|UniProtKB=A0A1D8PCV9	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_A08041g\|UniProtKB=Q6CHK1	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_02740\|UniProtKB=Q5B9P0	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_1G05230\|UniProtKB=Q4WJP8	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU00478\|UniProtKB=U9W570	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_12594\|UniProtKB=A7F4R9	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_00406\|UniProtKB=Q0V6F8	Phaeosphaeria nodorum	O
CRYNJ\|EnsemblGenome=CNB01170\|UniProtKB=Q5KMM5	Cryptococcus neoformans	O
PUCGT\|EnsemblGenome=PGTG_02535\|UniProtKB=E3JVL9	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_86647\|UniProtKB=F4NWD5	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_2204\|UniProtKB=F4P9V8	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_35570\|UniProtKB=F4P6V0	Batrachochytrium dendrobatidis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_12624\|UniProtKB=F4P784	Batrachochytrium dendrobatidis	O
DICDI\|dictyBase=DDB_G0268634\|UniProtKB=B0G0Y8	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_168745\|UniProtKB=F0ZLZ6	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0289121\|UniProtKB=Q86H13	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_150656\|UniProtKB=F0ZGW8	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_29_2680\|UniProtKB=E9AED0	Leishmania major	O
TRYB2\|Gene_ORFName=Tb927.3.3070\|UniProtKB=Q57ZK5	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_15_1480\|UniProtKB=Q4QF31	Leishmania major	O
TRYB2\|Gene_ORFName=Tb09.160.3590\|UniProtKB=Q38F46	Trypanosoma brucei	O
TRYB2\|Gene_ORFName=Tb09.160.3630\|UniProtKB=Q38F42	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_29_2440\|UniProtKB=E9AEA6	Leishmania major	O
TRYB2\|Gene_ORFName=Tb927.3.3340\|UniProtKB=Q57V52	Trypanosoma brucei	O
GIAIC\|EnsemblGenome=GL50803_23389\|UniProtKB=A8BMZ9	Giardia intestinalis	O
GIAIC\|Gene_ORFName=GL50803_0014058\|UniProtKB=A0A644EZ75	Giardia intestinalis	O
TRIV3\|Gene_ORFName=TVAG_456690\|UniProtKB=A2DBZ3	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_139380\|UniProtKB=A2E4B2	Trichomonas vaginalis	O
PHYRM\|Gene=H3GMG8_PHYRM\|UniProtKB=H3GMG8	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_02g080550v5\|UniProtKB=A0A2K3E0I9	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_13g605100v5\|UniProtKB=A0A2K3D1E3	Chlamydomonas reinhardtii	O
PLAF7\|EnsemblGenome=PF3D7_1209500.1\|UniProtKB=Q8I5V4	Plasmodium falciparum	O
PLAF7\|EnsemblGenome=PF3D7_1321500.1\|UniProtKB=Q8I6Z7	Plasmodium falciparum	O
PLAF7\|EnsemblGenome=PF3D7_1470500\|UniProtKB=Q8IKD3	Plasmodium falciparum	O
PLAF7\|EnsemblGenome=PF3D7_1321600\|UniProtKB=B3FEM7	Plasmodium falciparum	O
PARTE\|EnsemblGenome=GSPATT00012165001\|UniProtKB=A0D0P6	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00026232001\|UniProtKB=A0EF18	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00024350001\|UniProtKB=A0E8K4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00033829001\|UniProtKB=A0BZK9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00005060001\|UniProtKB=A0BP44	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00028410001\|UniProtKB=A0BFQ8	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00007223001\|UniProtKB=A0CDZ4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00019474001\|UniProtKB=A0DRT9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00011705001\|UniProtKB=A0CZB5	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00021356001\|UniProtKB=A0DXF6	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00032825001\|UniProtKB=A0BWQ6	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00007186001\|UniProtKB=A0CDV7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00016491001\|UniProtKB=A0DF61	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00022445001\|UniProtKB=A0E1V7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00022614001\|UniProtKB=A0E2C5	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00017245001\|UniProtKB=A0DIM1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00016009001\|UniProtKB=A0DDQ1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00019716001\|UniProtKB=A0DSJ5	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00016916001\|UniProtKB=A0DHL2	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00025458001\|UniProtKB=A0EBQ7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00026780001\|UniProtKB=A0EGL5	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00036148001\|UniProtKB=A0C8A0	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00036302001\|UniProtKB=A0C8Q0	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00026646001\|UniProtKB=A0EG81	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00013629001\|UniProtKB=A0D565	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00010500001\|UniProtKB=A0CU34	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00036826001\|UniProtKB=A0CB76	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00024359001\|UniProtKB=A0E8L3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00027162001\|UniProtKB=A0EHP5	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00028038001\|UniProtKB=A0BEN8	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00016442001\|UniProtKB=A0DEZ9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00038228001\|UniProtKB=A0CG66	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00006250001\|UniProtKB=A0C4N4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00026769001\|UniProtKB=A0EGK4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00031858001\|UniProtKB=A0BSV9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00033366001\|UniProtKB=A0BY96	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00012334001\|UniProtKB=A0D193	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00039546001\|UniProtKB=A0DK29	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00011621001\|UniProtKB=A0CZ03	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_268740\|UniProtKB=B8C004	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_261018\|UniProtKB=B8BRB2	Thalassiosira pseudonana	O
PHYRM\|Gene=H3GHE7_PHYRM\|UniProtKB=H3GHE7	Phytophthora ramorum	O
PHYRM\|Gene=H3GTZ2_PHYRM\|UniProtKB=H3GTZ2	Phytophthora ramorum	O
PHYRM\|Gene=H3GZZ5_PHYRM\|UniProtKB=H3GZZ5	Phytophthora ramorum	O
PHYRM\|Gene=H3GBS7_PHYRM\|UniProtKB=H3GBS7	Phytophthora ramorum	O
PHYRM\|Gene=H3GBT1_PHYRM\|UniProtKB=H3GBT1	Phytophthora ramorum	O
PHYRM\|Gene=H3GU47_PHYRM\|UniProtKB=H3GU47	Phytophthora ramorum	O
PHYRM\|Gene=H3HCP0_PHYRM\|UniProtKB=H3HCP0	Phytophthora ramorum	O
PHYRM\|Gene=H3HCQ7_PHYRM\|UniProtKB=H3HCQ7	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_02g143500v5\|UniProtKB=A0A2K3E451	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_09g389875v5\|UniProtKB=A0A2K3DE17	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_02g143350v5\|UniProtKB=A0A2K3E413	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_01g015200v5\|UniProtKB=A0A2K3E5T7	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_11g468100v5\|UniProtKB=A0A2K3D839	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_03g204689v5\|UniProtKB=A0A2K3DZP3	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_13g564766v5\|UniProtKB=A0A2K3CZ72	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_12g499250v5\|UniProtKB=A0A2K3D3E2	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_14g617650v5\|UniProtKB=A0A2K3CXT4	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_13g590600v5\|UniProtKB=A0A2K3D112	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_11g467673v5\|UniProtKB=A0A2K3D7N5	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_02g114100v5\|UniProtKB=A0A2K3E354	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_16g664150v5\|UniProtKB=A0A2K3CTQ5	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_12g559400v5\|UniProtKB=A0A2K3D5L0	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_12g509550v5\|UniProtKB=A0A2K3D2M9	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_14g617750v5\|UniProtKB=A0A2K3CXR2	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_13g567400v5\|UniProtKB=A0A2K3CZD9	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_13g603000v5\|UniProtKB=A0A2K3D180	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_12g499300v5\|UniProtKB=A0A2K3D3C8	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_14g617700v5\|UniProtKB=A0A2K3CXS8	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_12g557500v5\|UniProtKB=A0A2K3D5P8	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_02g141786v5\|UniProtKB=A0A2K3E4B4	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_02g109100v5\|UniProtKB=A0A2K3E2U1	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_10g454900v5\|UniProtKB=A0A2K3DBF7	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_16g664200v5\|UniProtKB=A0A2K3CTS8	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_02g143400v5\|UniProtKB=A0A2K3E402	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_02g119850v5\|UniProtKB=A0A2K3E3K8	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_07g342350v5\|UniProtKB=A0A2K3DKM3	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_06g289400v5\|UniProtKB=A0A2K3DQ75	Chlamydomonas reinhardtii	O
KLENI\|Gene_ORFName=KFL_001960100\|UniProtKB=A0A1Y1I296	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_000010350\|UniProtKB=A0A0U9HHT7	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_002670040\|UniProtKB=A0A1Y1I6A5	Klebsormidium nitens	O