PANTHER Gene Information

Gene Symbol(s):

pms2

Organism:

Danio rerio

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Gene Name:

Mismatch repair endonuclease PMS2

Gene ID:

pms2

Protein ID:

A0A8N7T7Z7

Persistent Id:

PTN002467796

Alternate Ids:

XP_693648(refSeq)	A0A8N7T7Z7_DANRE(UniProtKB-ID)
A0A8N7T7Z7(Synonym)
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PANTHER Classification

PANTHER Family:	DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL (PTHR10073)
PANTHER Subfamily:	MISMATCH REPAIR ENDONUCLEASE PMS2 (PTHR10073:SF52)
PANTHER GO-slim Molecular Function:	ATP hydrolysis activity
PANTHER GO-slim Biological Process:	mismatch repair
PANTHER GO-slim Cellular Component:	nuclear protein-containing complex
PANTHER protein class:	DNA metabolism protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	ATP hydrolysis activity, ATP binding, endonuclease activity, nuclease activity, ATP-dependent DNA damage sensor activity, mismatched DNA binding, hydrolase activity
GO BP Complete:	mismatch repair, DNA damage response
GO CC Complete:	nucleus, mismatch repair complex, MutLalpha complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=9122\|UniProtKB=P54278	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000018920.5\|UniProtKB=H2QU63	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000048669.1\|UniProtKB=A0A2I3STT5	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000018902.6\|UniProtKB=A0A2I3TMT9	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000007960.3\|UniProtKB=G3QY63	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000030421.3\|UniProtKB=A0A1D5QSH2	Macaca mulatta	LDO
MOUSE\|MGI=MGI=104288\|UniProtKB=P54279	Mus musculus	LDO
RAT\|RGD=1305483\|UniProtKB=A0A0G2JW47	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000007364.6\|UniProtKB=A0A3Q1M1S8	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000007590.5\|UniProtKB=F1RFM9	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000014072.4\|UniProtKB=A0A3Q2GY12	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000008459.6\|UniProtKB=A0A5F5XP35	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845010093.1\|UniProtKB=A0A8I3NGD0	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000008178.4\|UniProtKB=F7E4Y3	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000001944.4\|UniProtKB=A0A6I8P9S1	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010021776\|UniProtKB=F1NQJ3	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000013264.4\|UniProtKB=H9GJT7	Anolis carolinensis	LDO
XENLA\|Gene=pms2.L\|UniProtKB=A0A8J0TX93	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-998793\|UniProtKB=A0A7D9NKB2	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000003486.2\|UniProtKB=H2LEG9	Oryzias latipes	LDO
LEPOC\|Ensembl=ENSLOCG00000008495.1\|UniProtKB=W5MPN7	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000002674.3\|UniProtKB=F6XQD4	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118428751\|UniProtKB=A0A9J7N9K0	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC581506\|UniProtKB=A0A7M7REZ7	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00004064\|UniProtKB=G5EFG5	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG23320\|UniProtKB=A8Y473	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00100595\|UniProtKB=A0A2A6BMV3	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0011660\|UniProtKB=A1ZA03	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP007126\|UniProtKB=A0A1S4GV00	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC002932\|UniProtKB=D6WH35	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_326138\|UniProtKB=E9H6U5	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_311334\|UniProtKB=E9FWK5	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW016226\|UniProtKB=B7P0P2	Ixodes scapularis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g231142\|UniProtKB=A7SXZ4	Nematostella vectensis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g246770\|UniProtKB=A7SQJ8	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG21244\|UniProtKB=B3RPU8	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_10263\|UniProtKB=A9V5P8	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_31692\|UniProtKB=A9UV76	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_26866\|UniProtKB=A9V3R9	Monosiga brevicollis	LDO
YEAST\|SGD=S000005026\|UniProtKB=P14242	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AER421W\|UniProtKB=Q755U7	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000197853\|UniProtKB=A0A1D8PII6	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_E10769g\|UniProtKB=Q6C6B8	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_01564\|UniProtKB=Q5BD16	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_8G05820\|UniProtKB=Q4WC38	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU09373\|UniProtKB=Q7SCN8	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_04226\|UniProtKB=A7EFY5	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_04311\|UniProtKB=Q0UVA3	Phaeosphaeria nodorum	O
EMENI\|EnsemblGenome=ANIA_06316\|UniProtKB=Q5AZG4	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_2G13410\|UniProtKB=Q4X0H9	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU08020\|UniProtKB=Q7SAM1	Neurospora crassa	LDO
SCLS1\|Gene_ORFName=SS1G_09785\|UniProtKB=A7EWS6	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_06058\|UniProtKB=Q0UQA6	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPAC19G12.02c\|UniProtKB=P54280	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_02187\|UniProtKB=B6K1S5	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNC02500\|UniProtKB=Q5KKM6	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_01932\|UniProtKB=A0A0D1E8Q1	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_02903\|UniProtKB=E3JWN7	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_89533\|UniProtKB=F4P5P3	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_155170\|UniProtKB=C4LW71	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0283981\|UniProtKB=Q54QA0	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_152626\|UniProtKB=F0ZLV8	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_17_0660\|UniProtKB=Q4QEC0	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb927.5.2020\|UniProtKB=Q57ZS1	Trypanosoma brucei	LDO
LEIMA\|EnsemblGenome=LMJF_35_1660\|UniProtKB=E9AEY8	Leishmania major	O
TRYB2\|Gene_ORFName=Tb09.211.4840\|UniProtKB=Q38D26	Trypanosoma brucei	O
GIAIC\|EnsemblGenome=GL50803_14195\|UniProtKB=A8B4I6	Giardia intestinalis	LDO
GIAIC\|EnsemblGenome=GL50803_33083\|UniProtKB=E2RU87	Giardia intestinalis	O
GIAIC\|EnsemblGenome=GL50803_16149\|UniProtKB=A8BWU9	Giardia intestinalis	O
TRIV3\|Gene_ORFName=TVAG_226330\|UniProtKB=A2ER67	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_364540\|UniProtKB=A2E9G5	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_052060\|UniProtKB=A2F4K2	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_302400\|UniProtKB=A2EGR5	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_005070\|UniProtKB=A2G2B4	Trichomonas vaginalis	LDO
PLAF7\|EnsemblGenome=PF3D7_0726300\|UniProtKB=Q8IBJ3	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00010239001\|UniProtKB=A0CT88	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00026562001\|UniProtKB=A0EFZ8	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_264783\|UniProtKB=B8CFF0	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3G7I0_PHYRM\|UniProtKB=H3G7I0	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_04g227000v5\|UniProtKB=A0A2K3DUP7	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00045p00213360\|UniProtKB=W1NX88	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_84G00580\|UniProtKB=A0A0K9NNT8	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma06_g21630\|UniProtKB=A0A804JIV5	Musa acuminata subsp. malaccensis	LDO
SORBI\|EnsemblGenome=SORBI_3004G199200\|UniProtKB=A0A194YQM4	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb183500\|UniProtKB=A0A1D6Q3Y8	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os02g0592300\|UniProtKB=A0A0P0VL29	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_3g47472v3\|UniProtKB=I1IB41	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0590230\|UniProtKB=A0A8I6YD86	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS6B02G235900\|UniProtKB=A0A3B6PNG6	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6A02G205700\|UniProtKB=A0A3B6NQ87	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6D02G190900\|UniProtKB=A0A3B6QHD5	Triticum aestivum	LDO
NELNU\|Gene=LOC104606160\|UniProtKB=A0A1U8B1T7	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110788606\|UniProtKB=A0A9R0JVR7	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr01g0001541\|UniProtKB=A0A251SVE8	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C500297940\|UniProtKB=A0A9R1X8J6	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a024383mg\|UniProtKB=A0A022S1N6	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_08309\|UniProtKB=A0A1U8FBY8	Capsicum annuum	LDO
SOLLC\|EnsemblGenome=Solyc09g074990.3\|UniProtKB=A0A3Q7I7B5	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107818778\|UniProtKB=A0A1S4CGL4	Nicotiana tabacum	O
TOBAC\|Gene=LOC107787641\|UniProtKB=A0A1S3ZKE5	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi07g00307\|UniProtKB=D7U271	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_K03466\|UniProtKB=A0A059A7F8	Eucalyptus grandis	LDO
BRACM\|EnsemblGenome=Bra018549\|UniProtKB=M4DPV8	Brassica campestris	LDO
ARATH\|TAIR=locus=2133274\|UniProtKB=Q941I6	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107946086\|UniProtKB=A0A1U8ND41	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_004628\|UniProtKB=A0A061DRJ4	Theobroma cacao	LDO
POPTR\|EnsemblGenome=POPTR_014G130800v3\|UniProtKB=B9I9S8	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_01G217500\|UniProtKB=A0A2C9WQD0	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1177300\|UniProtKB=B9SAN7	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_02G155200\|UniProtKB=I1JFI1	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_10G019200\|UniProtKB=K7LGX1	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_1g088720\|UniProtKB=G7IF83	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr08_12430\|UniProtKB=A0A2I4E2G1	Juglans regia	LDO
JUGRE\|EnsemblGenome=Jr08_12420\|UniProtKB=A0A2I4E2F6	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_7G396420\|UniProtKB=A0A0A0K976	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_8G259200\|UniProtKB=A0A251N3G4	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_121896\|UniProtKB=D8SPD6	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_171139\|UniProtKB=D8RFY2	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c8_22650\|UniProtKB=A0A2K1K8F7	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0103s0058\|UniProtKB=A0A2R6WE11	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_000600360\|UniProtKB=A0A1Y1HU70	Klebsormidium nitens	LDO
METAC\|EnsemblGenome=MA_0522\|UniProtKB=Q8TTB5	Methanosarcina acetivorans	O
HALSA\|EnsemblGenome=VNG_0159G\|UniProtKB=Q9HSM6	Halobacterium salinarum	O
CHLAA\|EnsemblGenome=Caur_1133\|UniProtKB=A9WJ86	Chloroflexus aurantiacus	O
CLOBH\|Gene_OrderedLocusName=CBO1799\|UniProtKB=A5I2S1	Clostridium botulinum	O
STRR6\|EnsemblGenome=spr0160\|UniProtKB=P0A3R2	Streptococcus pneumoniae	O
STAA8\|EnsemblGenome=SAOUHSC_01273\|UniProtKB=Q93T05	Staphylococcus aureus	O
LISMO\|EnsemblGenome=CAC99482\|UniProtKB=Q8Y788	Listeria monocytogenes	O
BACSU\|EnsemblGenome=BSU_17050\|UniProtKB=P49850	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_3768\|UniProtKB=Q81A26	Bacillus cereus	O
THEMA\|EnsemblGenome=TM_0022\|UniProtKB=P74925	Thermotoga maritima	O
DEIRA\|EnsemblGenome=DR_1696\|UniProtKB=Q9RTR0	Deinococcus radiodurans	O
GLOVI\|Gene=mutL\|UniProtKB=Q7NL47	Gloeobacter violaceus	O
LEPIN\|EnsemblGenome=LA_1175\|UniProtKB=Q8F6X4	Leptospira interrogans	O
BACTN\|EnsemblGenome=BT_3851\|UniProtKB=Q8A120	Bacteroides thetaiotaomicron	O
CHLTR\|EnsemblGenome=CT_575\|UniProtKB=O84579	Chlamydia trachomatis	O
RHOBA\|EnsemblGenome=RB7883\|UniProtKB=Q7UMZ3	Rhodopirellula baltica	O
AQUAE\|EnsemblGenome=aq_1578\|UniProtKB=O67518	Aquifex aeolicus	O
THEYD\|EnsemblGenome=THEYE_A2083\|UniProtKB=B5YIZ6	Thermodesulfovibrio yellowstonii	O
DICTD\|EnsemblGenome=Dtur_1078\|UniProtKB=B8E280	Dictyoglomus turgidum	O
FUSNN\|EnsemblGenome=FN0462\|UniProtKB=Q8RG56	Fusobacterium nucleatum	O
NEIMB\|EnsemblGenome=NMB1442\|UniProtKB=Q9JYT2	Neisseria meningitidis serogroup b	O
GEOSL\|EnsemblGenome=GSU2001\|UniProtKB=Q74BP0	Geobacter sulfurreducens	O
BRADU\|EnsemblGenome=BAC52758\|UniProtKB=Q89DE6	Bradyrhizobium diazoefficiens	O
COXBU\|EnsemblGenome=CBU_1083\|UniProtKB=Q83CM9	Coxiella burnetii	O
HAEIN\|EnsemblGenome=HI_0067\|UniProtKB=P44494	Haemophilus influenzae	O
SHEON\|Gene_OrderedLocusName=SO_0601\|UniProtKB=Q8EJ70	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_0345\|UniProtKB=Q9KV13	Vibrio cholerae	O
XANCP\|EnsemblGenome=XCC2298\|UniProtKB=Q8P8E4	Xanthomonas campestris	O
PSEAE\|EnsemblGenome=PA4946\|UniProtKB=Q9HUL8	Pseudomonas aeruginosa	O
SALTY\|EnsemblGenome=STM4359\|UniProtKB=P14161	Salmonella typhimurium	O
YERPE\|EnsemblGenome=YP_0527\|UniProtKB=Q8ZIW4	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAE78171\|UniProtKB=P23367	Escherichia coli	O