PANTHER Gene Information

Gene Symbol(s):

prss2a

Organism:

Danio rerio

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Gene Name:

Trypsinogen 1a

Gene ID:

ZDB-GENE-030131-1173

Protein ID:

F1R894

Persistent Id:

PTN001208021

Alternate Ids:

339895765(GI)	JQ999996(EMBL)
322453(GeneID)	NM_199605(refSeq)
F1R894(Synonym)	ZDB-GENE-030131-1173(ZFIN)
F1R894_DANRE(UniProtKB-ID)	AGB67367(EMBL-CDS)
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PANTHER Classification

PANTHER Family:	TRYPSIN-RELATED (PTHR24264)
PANTHER Subfamily:	TRYPSINOGEN 1A-RELATED (PTHR24264:SF6)
PANTHER GO-slim Molecular Function:	serine-type endopeptidase activity
PANTHER GO-slim Biological Process:	proteolysis
PANTHER GO-slim Cellular Component:	extracellular space
PANTHER protein class:	serine protease

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	serine-type endopeptidase activity, serine-type peptidase activity, peptidase activity, hydrolase activity
GO BP Complete:	proteolysis
GO CC Complete:	extracellular space

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Immune System, Neutrophil degranulation, Innate Immune System, Collagen degradation, Extracellular matrix organization, Degradation of the extracellular matrix, Activation of Matrix Metalloproteinases

Orthologs

ID	Organism	Type
PIG\|Ensembl=ENSSSCG00000035586.3\|UniProtKB=A0A287A5E6	Sus scrofa	O
ORNAN\|Ensembl=ENSOANG00000051339.1\|UniProtKB=A0A6I8NVG7	Ornithorhynchus anatinus	O
HUMAN\|HGNC=43788\|UniProtKB=Q8NHM4	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000052633.1\|UniProtKB=A0A2I3RV51	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000037579.1\|UniProtKB=A0A2I2Z0Q5	Gorilla gorilla gorilla	O
PANTR\|Ensembl=ENSPTRG00000052186.1\|UniProtKB=A0A2I3T9A0	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000042185.1\|UniProtKB=A0A2I2YW45	Gorilla gorilla gorilla	O
GORGO\|Ensembl=ENSGGOG00000043062.1\|UniProtKB=A0A2I2YNY0	Gorilla gorilla gorilla	O
HUMAN\|HGNC=9475\|UniProtKB=P07477	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000043326.1\|UniProtKB=A0A2J8QUC3	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000037016.1\|UniProtKB=A0A2I2YAT3	Gorilla gorilla gorilla	O
HUMAN\|HGNC=9486\|UniProtKB=P35030	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000049562.1\|UniProtKB=A0A2I3RLD2	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000013297.3\|UniProtKB=G3RBV4	Gorilla gorilla gorilla	O
PANTR\|Ensembl=ENSPTRG00000043298.1\|UniProtKB=A0A2I3TEM4	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000040655.1\|UniProtKB=A0A2I2ZKU5	Gorilla gorilla gorilla	O
HUMAN\|HGNC=9483\|UniProtKB=P07478	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000052290.1\|UniProtKB=A0A2I3RIT4	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000043797.1\|UniProtKB=A0A2I3RGJ4	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000028503.2\|UniProtKB=G3RW16	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000016286.4\|UniProtKB=F7HBQ8	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000052519.1\|UniProtKB=F6X2B2	Macaca mulatta	O
MACMU\|Ensembl=ENSMMUG00000051032.1\|UniProtKB=F6X291	Macaca mulatta	O
MOUSE\|MGI=MGI=98839\|UniProtKB=Q9Z1R9	Mus musculus	O
MOUSE\|MGI=MGI=3646222\|UniProtKB=Q792Y9	Mus musculus	O
MOUSE\|MGI=MGI=102758\|UniProtKB=Q792Z0	Mus musculus	O
MOUSE\|MGI=MGI=3641889\|UniProtKB=Q792Y8	Mus musculus	O
RAT\|RGD=3418\|UniProtKB=P00763	Rattus norvegicus	O
RAT\|RGD=7618053\|UniProtKB=A0A8I5Y5M6	Rattus norvegicus	O
RAT\|RGD=1359400\|UniProtKB=A0A8I6APH4	Rattus norvegicus	O
RAT\|RGD=1597830\|UniProtKB=W4VSR6	Rattus norvegicus	O
MOUSE\|MGI=MGI=102757\|UniProtKB=Q9R0T7	Mus musculus	O
MOUSE\|MGI=MGI=3687012\|UniProtKB=Q792Z1	Mus musculus	O
MOUSE\|MGI=MGI=102759\|UniProtKB=P07146	Mus musculus	O
MOUSE\|MGI=MGI=102756\|UniProtKB=Q9QUK9	Mus musculus	O
RAT\|RGD=3417\|UniProtKB=P00762	Rattus norvegicus	O
RAT\|RGD=1560283\|UniProtKB=A0A8I5ZME9	Rattus norvegicus	O
RAT\|RGD=1311446\|UniProtKB=D3ZQV0	Rattus norvegicus	O
BOVIN\|Gene=TRY2_BOVIN\|UniProtKB=Q29463	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000021565.5\|UniProtKB=A7YWU9	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000016478.3\|UniProtKB=C6L245	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000015872.4\|UniProtKB=A0A9L0S0F6	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000011878.5\|UniProtKB=A0A5F5XYN0	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845018895.1\|UniProtKB=A0A8I3PD99	Canis lupus familiaris	O
CANLF\|Gene=TRY2_CANLF\|UniProtKB=P06872	Canis lupus familiaris	O
ORNAN\|Ensembl=ENSOANG00000039456.1\|UniProtKB=A0A6I8PP17	Ornithorhynchus anatinus	O
ORNAN\|Ensembl=ENSOANG00000010647.3\|UniProtKB=F6XSU3	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010000807.1\|UniProtKB=A0A8V0X8V9	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000035610.1\|UniProtKB=A0A803SN81	Anolis carolinensis	O
CHICK\|Ensembl=ENSGALG00010023501.1\|UniProtKB=A2JDL7	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010023541\|UniProtKB=Q90629	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010023495.1\|UniProtKB=A0A8V0ZN26	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010026260.1\|UniProtKB=A0A1D5PN36	Gallus gallus	O
GORGO\|Ensembl=ENSGGOG00000038309.1\|UniProtKB=A0A2I2ZUM9	Gorilla gorilla gorilla	O
MOUSE\|MGI=MGI=3780832\|UniProtKB=F6R7E8	Mus musculus	O
MOUSE\|MGI=MGI=1920876\|UniProtKB=Q9CPN7	Mus musculus	O
RAT\|RGD=708585\|UniProtKB=P12788	Rattus norvegicus	O
MOUSE\|MGI=MGI=1914623\|UniProtKB=Q9CPN9	Mus musculus	O
RAT\|Gene=TRYB_RAT\|UniProtKB=P32822	Rattus norvegicus	O
RAT\|RGD=1563848\|UniProtKB=P32821	Rattus norvegicus	O
RAT\|RGD=708437\|UniProtKB=P08426	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000050323\|UniProtKB=P00760	Bos taurus	O
PIG\|Gene=TRYP_PIG\|UniProtKB=P00761	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000036013.3\|UniProtKB=A0A287B5W2	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000029148.3\|UniProtKB=A0A3Q2H2H2	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000033873.3\|UniProtKB=A0A3Q2I7T0	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000039223.3\|UniProtKB=A0A5F5PMA7	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000033380.3\|UniProtKB=A0A3Q2IA10	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000018949.5\|UniProtKB=M3WP64	Felis catus	O
CANLF\|Gene=PRSS1\|UniProtKB=P06871	Canis lupus familiaris	O
CANLF\|Ensembl=ENSCAFG00845019799.1\|UniProtKB=A0A8I3P0A5	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000043441.1\|UniProtKB=A0A5F8H3M6	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000000845.4\|UniProtKB=F7BIQ2	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000000887.4\|UniProtKB=F7BIT1	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000000681.2\|UniProtKB=F6WME4	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000000899.3\|UniProtKB=F7A744	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000000671.3\|UniProtKB=F6SB70	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000012168.3\|UniProtKB=F7DD53	Ornithorhynchus anatinus	O
ORNAN\|Ensembl=ENSOANG00000008640.3\|UniProtKB=F6VSH7	Ornithorhynchus anatinus	O
ORNAN\|Ensembl=ENSOANG00000008891.3\|UniProtKB=A0A6I8PDX3	Ornithorhynchus anatinus	O
CHICK\|Gene=TRY2_CHICK\|UniProtKB=Q90628	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010023814.1\|UniProtKB=A0A8V1A2H3	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010023834.1\|UniProtKB=A0A8V0ZPB4	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010023723.1\|UniProtKB=A0A8V0ZW57	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010023678.1\|UniProtKB=A0A8V0ZTX9	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010023615.1\|UniProtKB=A0A8V0ZVQ2	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010023729.1\|UniProtKB=A0A8V0ZU57	Gallus gallus	O
CHICK\|Gene=TRY1_CHICK\|UniProtKB=Q90627	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000007958.4\|UniProtKB=H9GDA9	Anolis carolinensis	O
ANOCA\|Ensembl=ENSACAG00000044970.1\|UniProtKB=A0A803TKZ9	Anolis carolinensis	O
ANOCA\|Ensembl=ENSACAG00000016757.4\|UniProtKB=A0A803SM14	Anolis carolinensis	O
ANOCA\|Ensembl=ENSACAG00000043171.1\|UniProtKB=A0A803SSB5	Anolis carolinensis	O
XENLA\|Gene=LOC108695969\|UniProtKB=A0A1L8FPS5	Xenopus laevis	O
XENLA\|Gene=LOC108697291\|UniProtKB=A0A1L8FHU8	Xenopus laevis	O
XENTR\|Ensembl=ENSXETG00000013549\|UniProtKB=A0A6I8QQ56	Xenopus tropicalis	O
XENLA\|Gene=LOC121396621\|UniProtKB=A0A8J1LF74	Xenopus laevis	O
XENLA\|Gene=klk1.L\|UniProtKB=A0A1L8FPS4	Xenopus laevis	O
XENTR\|Gene=LOC100485347\|UniProtKB=A0A8J0QXG6	Xenopus tropicalis	O
XENTR\|Xenbase=XB-GENE-5894648\|UniProtKB=A0A6I8SIB6	Xenopus tropicalis	O
XENLA\|Gene=LOC121398031\|UniProtKB=A0A8J1LS34	Xenopus laevis	O
XENTR\|Ensembl=ENSXETG00000042697\|UniProtKB=A0A803KG87	Xenopus tropicalis	O
XENLA\|Gene=TRY2_XENLA\|UniProtKB=P70059	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-5776262\|UniProtKB=Q5EBE2	Xenopus tropicalis	O
XENLA\|Gene=LOC121395798\|UniProtKB=A0A1L8FHX6	Xenopus laevis	O
XENLA\|Gene=LOC108705898\|UniProtKB=A0A1L8FHY7	Xenopus laevis	O
XENTR\|Gene=LOC116412105\|UniProtKB=A0A8J1JYA0	Xenopus tropicalis	O
XENTR\|Gene=LOC116406450\|UniProtKB=A0A8J0R6D0	Xenopus tropicalis	O
XENLA\|Gene=LOC108695985\|UniProtKB=A0A1L8FHZ8	Xenopus laevis	O
XENTR\|Ensembl=ENSXETG00000048942\|UniProtKB=A0A6I8R8N0	Xenopus tropicalis	O
XENLA\|Gene=MGC64344\|UniProtKB=Q7SZ06	Xenopus laevis	O
XENLA\|Gene=TRY1_XENLA\|UniProtKB=P19799	Xenopus laevis	O
XENLA\|Gene=LOC108696664\|UniProtKB=A0A1L8HWZ8	Xenopus laevis	O
XENLA\|Gene=LOC108697140\|UniProtKB=A0A8J1LCA5	Xenopus laevis	O
XENLA\|Gene=LOC108695979\|UniProtKB=A0A8J0T6W0	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-6065254\|UniProtKB=F6YJN1	Xenopus tropicalis	O
XENTR\|Gene_ORFName=XENTR_v90029055mg\|UniProtKB=Q5M976	Xenopus tropicalis	O
XENTR\|Gene=LOC116412106\|UniProtKB=A0A8J1JUG2	Xenopus tropicalis	O
XENTR\|Gene=LOC101730924\|UniProtKB=A0A8J1JUF3	Xenopus tropicalis	O
XENLA\|Gene=LOC108695980\|UniProtKB=A0A1L8FHW7	Xenopus laevis	O
XENTR\|Ensembl=ENSXETG00000043704\|UniProtKB=A0A803J9F5	Xenopus tropicalis	O
XENTR\|Xenbase=XB-GENE-6453489\|UniProtKB=Q5M902	Xenopus tropicalis	O
XENLA\|Gene=LOC108703879\|UniProtKB=A0A8J1LV68	Xenopus laevis	O
XENLA\|Gene=LOC108703877\|UniProtKB=A0A8J1LTP1	Xenopus laevis	O
XENTR\|Ensembl=ENSXETG00000043378\|UniProtKB=A0A803K5Z6	Xenopus tropicalis	O
XENLA\|Gene=LOC108695987\|UniProtKB=A0A8J0T920	Xenopus laevis	O
XENLA\|Gene=LOC108697909\|UniProtKB=A0A1L8FDL8	Xenopus laevis	O
XENLA\|Gene=LOC121395739\|UniProtKB=A0A1L8FHZ3	Xenopus laevis	O
XENLA\|Gene=LOC108695984\|UniProtKB=A0A1L8FHY1	Xenopus laevis	O
XENLA\|Gene=LOC108695986\|UniProtKB=A0A1L8FHY0	Xenopus laevis	O
XENTR\|Gene=LOC100498083\|UniProtKB=A0A8J0SCE5	Xenopus tropicalis	O
XENTR\|Gene=LOC101730988\|UniProtKB=A0A8J0SDG2	Xenopus tropicalis	O
XENTR\|Gene_ORFName=XENTR_v90029049mg\|UniProtKB=L7N2H9	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000022909.1\|UniProtKB=A4UWM7	Oryzias latipes	LDO
LEPOC\|Ensembl=ENSLOCG00000004195.1\|UniProtKB=W5M9F9	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000020354.1\|UniProtKB=F6UWG2	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000019093.1\|UniProtKB=F6WT44	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000003513.3\|UniProtKB=F7BHL3	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000016095.2\|UniProtKB=F6VJ33	Ciona intestinalis	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_78192\|UniProtKB=C3ZLA6	Branchiostoma floridae	O
BRAFL\|Gene=LOC118409977\|UniProtKB=A0A9J7MHK2	Branchiostoma floridae	O
BRAFL\|Gene=LOC118423916\|UniProtKB=A0A9J7LS87	Branchiostoma floridae	O
BRAFL\|Gene=LOC118403401\|UniProtKB=A0A9J7HEY3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118413629\|UniProtKB=A0A9J7KYW5	Branchiostoma floridae	O
BRAFL\|Gene=LOC118422460\|UniProtKB=A0A9J7LRL2	Branchiostoma floridae	O
BRAFL\|Gene=LOC118420057\|UniProtKB=A0A9J7MWK5	Branchiostoma floridae	O
BRAFL\|Gene=LOC118417950\|UniProtKB=A0A9J7MUP1	Branchiostoma floridae	O
BRAFL\|Gene=LOC118409976\|UniProtKB=A0A9J7MGU6	Branchiostoma floridae	O
TRIAD\|EnsemblGenome=TriadG64384\|UniProtKB=B3SC31	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG25111\|UniProtKB=B3RY72	Trichoplax adhaerens	O
THAPS\|EnsemblGenome=THAPS_23543\|UniProtKB=B5YNG0	Thalassiosira pseudonana	O