PANTHER Gene Information

Gene Symbol(s):

PHC2

Organism:

Danio rerio

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Gene Name:

Polyhomeotic homolog 2b (Drosophila)

Gene ID:

ZDB-GENE-040426-1113

Protein ID:

F6P2R0

Persistent Id:

PTN002284149

Alternate Ids:

ENSDARP00000018055(Ensembl_PRO)	NM_201202(refSeq)
F6P2R0(Synonym)	ENSDART00000019706(Ensembl_TRS)
CR382321(EMBL)	F6P2R0_DANRE(UniProtKB-ID)
348605119(GI)	ENSDARG00000013224(Ensembl)
394177(GeneID)	ZDB-GENE-040426-1113(ZFIN)
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PANTHER Classification

PANTHER Family:	POLYCOMB GROUP PROTEIN (PTHR12247)
PANTHER Subfamily:	POLYHOMEOTIC-LIKE PROTEIN 2 (PTHR12247:SF86)
PANTHER GO-slim Molecular Function:	chromatin binding histone binding
PANTHER GO-slim Biological Process:	negative regulation of DNA-templated transcription
PANTHER GO-slim Cellular Component:	PRC1 complex
PANTHER protein class:	chromatin/chromatin-binding, or -regulatory protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	DNA binding, zinc ion binding, histone binding, metal ion binding, chromatin binding
GO BP Complete:	negative regulation of DNA-templated transcription
GO CC Complete:	nucleus, PRC1 complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=3182\|UniProtKB=P78364	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000004647.6\|UniProtKB=A0A2I3SP68	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000010735.3\|UniProtKB=G3RWP3	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000017843.4\|UniProtKB=A0A5F7ZKZ6	Macaca mulatta	O
MOUSE\|MGI=MGI=103248\|UniProtKB=Q64028	Mus musculus	O
RAT\|RGD=1309203\|UniProtKB=A0A8I6AHM8	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000018205.6\|UniProtKB=E1BHH0	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000000661.5\|UniProtKB=I3LCS6	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000015666.4\|UniProtKB=F6UDA8	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000015277.6\|UniProtKB=M3WMA6	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845028815.1\|UniProtKB=A0A8I3Q6E5	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000017995.5\|UniProtKB=A0A5F8H689	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000043198.1\|UniProtKB=F7F8M0	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010022842.1\|UniProtKB=A0A8V0ZJZ8	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000017447.4\|UniProtKB=G1KTY4	Anolis carolinensis	O
XENLA\|Gene=phc1.L\|UniProtKB=A0A1L8FIC2	Xenopus laevis	O
XENLA\|Gene=phc1.S\|UniProtKB=A0A8J0TDY1	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-1013248\|UniProtKB=F6TCW7	Xenopus tropicalis	O
HUMAN\|HGNC=3183\|UniProtKB=Q8IXK0	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000000505.7\|UniProtKB=H2PYL7	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000003599.3\|UniProtKB=G3S4V0	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000003269.4\|UniProtKB=F7GQB5	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1860454\|UniProtKB=Q9QWH1	Mus musculus	LDO
RAT\|RGD=1307912\|UniProtKB=D4A0M3	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000004603.6\|UniProtKB=E1BFG7	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000025344.4\|UniProtKB=I3LIR0	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000017179.4\|UniProtKB=F7AZ37	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000003574.5\|UniProtKB=M3W0K3	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845005005.1\|UniProtKB=A0A8I3MYF1	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000017114.5\|UniProtKB=F6U443	Monodelphis domestica	LDO
CHICK\|Ensembl=ENSGALG00010017685.1\|UniProtKB=A0A8V0YVZ7	Gallus gallus	LDO
XENLA\|Gene=phc2.L\|UniProtKB=A0A8J1L4N1	Xenopus laevis	LDO
XENLA\|Gene=phc2\|UniProtKB=Q4V7W5	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-996998\|UniProtKB=A0A803J520	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000002951.2\|UniProtKB=A0A3B3IA83	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000007405.3\|UniProtKB=H2LT69	Oryzias latipes	LDO
LEPOC\|Ensembl=ENSLOCG00000003682.1\|UniProtKB=W5M7L5	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118430308\|UniProtKB=A0A9J7MAA4	Branchiostoma floridae	LDO
DROME\|FlyBase=FBgn0032330\|UniProtKB=Q9VKL0	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP010158\|UniProtKB=A0A1S4H349	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC003752\|UniProtKB=A0A139WKT0	Tribolium castaneum	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g187589\|UniProtKB=A7SAH5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g20650\|UniProtKB=A7SAH4	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG58269\|UniProtKB=B3S1B9	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG58097\|UniProtKB=B3S2P2	Trichoplax adhaerens	O