PANTHER Gene Information

Gene Symbol(s):

OTTDARP00000002003

Organism:

Danio rerio

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Gene Name:

Hemoglobin, beta adult 2

Gene ID:

ZDB-GENE-040801-164

Protein ID:

Q6ZM12

Persistent Id:

PTN000154434

Alternate Ids:

CAE48992(EMBL-CDS)	82206405(GI)
445037(GeneID)	ENSDARG00000069734(Ensembl)
AL935210(EMBL)	Q6ZM12_DANRE(UniProtKB-ID)
Q6ZM12(Synonym)	ENSDARP00000053076(Ensembl_PRO)
NP_001003431(refSeq)	ENSDART00000053077(Ensembl_TRS)
ZDB-GENE-040801-164(ZFIN)
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PANTHER Classification

PANTHER Family:	HEMOGLOBIN FAMILY MEMBER (PTHR11442)
PANTHER Subfamily:	HEMOGLOBIN, BETA ADULT 2 (PTHR11442:SF101)
PANTHER GO-slim Molecular Function:	organic acid binding heme binding antioxidant activity protein binding oxidoreductase activity, acting on peroxide as acceptor
PANTHER GO-slim Biological Process:	cellular catabolic process
PANTHER GO-slim Cellular Component:	protein-containing complex extracellular space cytosol
PANTHER protein class:	globin

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	peroxidase activity, oxygen binding, metal ion binding, oxygen carrier activity, heme binding, haptoglobin binding
GO BP Complete:	oxygen transport, hydrogen peroxide catabolic process
GO CC Complete:	hemoglobin complex, haptoglobin-hemoglobin complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Cellular responses to stimuli, Erythrocytes take up oxygen and release carbon dioxide, O2/CO2 exchange in erythrocytes, Neutrophil degranulation, Cellular response to chemical stress, Cytoprotection by HMOX1, Erythrocytes take up carbon dioxide and release oxygen, Transport of small molecules, Immune System, Vesicle-mediated transport, Binding and Uptake of Ligands by Scavenger Receptors, Innate Immune System, Scavenging of heme from plasma, Cellular responses to stress, Heme signaling

Orthologs

ID	Organism	Type
MONDO\|Ensembl=ENSMODG00000016637.3\|UniProtKB=F7GH03	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000039904.1\|UniProtKB=A0A6I8PII1	Ornithorhynchus anatinus	O
HUMAN\|HGNC=4829\|UniProtKB=P02042	Homo sapiens	O
GORGO\|Ensembl=ENSGGOG00000028344.2\|UniProtKB=G3RYX7	Gorilla gorilla gorilla	O
GORGO\|Ensembl=ENSGGOG00000021936.2\|UniProtKB=G3SIN5	Gorilla gorilla gorilla	O
PANTR\|Ensembl=ENSPTRG00000003238\|UniProtKB=P61772	Pan troglodytes	O
GORGO\|Gene=HBD\|UniProtKB=P61773	Gorilla gorilla gorilla	O
HUMAN\|HGNC=4827\|UniProtKB=P68871	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000040047\|UniProtKB=P68873	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000043805\|UniProtKB=P02024	Gorilla gorilla gorilla	O
MACMU\|Gene=HBB\|UniProtKB=P02026	Macaca mulatta	O
MOUSE\|MGI=MGI=96025\|UniProtKB=B2RVB7	Mus musculus	O
MOUSE\|MGI=MGI=96022\|UniProtKB=P02089	Mus musculus	O
MOUSE\|MGI=MGI=96021\|UniProtKB=P02088	Mus musculus	O
MOUSE\|MGI=MGI=5474850\|UniProtKB=A8DUK4	Mus musculus	O
RAT\|Ensembl=ENSRNOG00000047098\|UniProtKB=P11517	Rattus norvegicus	O
RAT\|RGD=2783\|UniProtKB=P02091	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000052199.1\|UniProtKB=A0A3Q1MGU4	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000038748\|UniProtKB=P02081	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000047356.2\|UniProtKB=G3N1Y3	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000037644\|UniProtKB=P02070	Bos taurus	O
PIG\|Gene=HBB\|UniProtKB=P02067	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000014727.5\|UniProtKB=F1RII5	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000014725.6\|UniProtKB=A0A5G2QRW3	Sus scrofa	O
HORSE\|Gene=HBB\|UniProtKB=P02062	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000010020.4\|UniProtKB=F6RDD3	Equus caballus	O
FELCA\|Gene=HBB\|UniProtKB=P07412	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845020234.1\|UniProtKB=A0A1K0GGH0	Canis lupus familiaris	O
CANLF\|Gene=HBB\|UniProtKB=P60524	Canis lupus familiaris	O
MACMU\|Ensembl=ENSMMUG00000041831.2\|UniProtKB=A0A5F7ZQJ6	Macaca mulatta	O
BOVIN\|Ensembl=ENSBTAG00000037815.3\|UniProtKB=E1B976	Bos taurus	O
HUMAN\|HGNC=4831\|UniProtKB=P69891	Homo sapiens	O
PANTR\|Gene=HBG1\|UniProtKB=P61920	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000026413.2\|UniProtKB=G3SBL4	Gorilla gorilla gorilla	O
PANTR\|Ensembl=ENSPTRG00000028731.5\|UniProtKB=H2R5L8	Pan troglodytes	O
GORGO\|Gene=HBG1\|UniProtKB=P62741	Gorilla gorilla gorilla	O
HUMAN\|HGNC=4832\|UniProtKB=P69892	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000043688\|UniProtKB=P61921	Pan troglodytes	O
GORGO\|Gene=HBG2\|UniProtKB=P62742	Gorilla gorilla gorilla	O
MACMU\|Gene=HBG\|UniProtKB=P68077	Macaca mulatta	O
HUMAN\|HGNC=4830\|UniProtKB=P02100	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000022526\|UniProtKB=Q6LDH1	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000024137\|UniProtKB=Q6LDH0	Gorilla gorilla gorilla	O
MACMU\|Gene=HBE1\|UniProtKB=Q28507	Macaca mulatta	O
MOUSE\|MGI=MGI=96023\|UniProtKB=P04443	Mus musculus	O
RAT\|RGD=1564524\|UniProtKB=O88753	Rattus norvegicus	O
MOUSE\|MGI=MGI=96024\|UniProtKB=P04444	Mus musculus	O
RAT\|RGD=620306\|UniProtKB=O88754	Rattus norvegicus	O
MOUSE\|MGI=MGI=96027\|UniProtKB=P02104	Mus musculus	O
RAT\|RGD=1591909\|UniProtKB=A0A8I5ZV52	Rattus norvegicus	O
RAT\|RGD=1305115\|UniProtKB=O88752	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000039178\|UniProtKB=P06642	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000037751\|UniProtKB=P06643	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000036777.2\|UniProtKB=A0A287BS91	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000031449.2\|UniProtKB=A0A3Q2GYX5	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000030768.3\|UniProtKB=A0A1K0FUK6	Equus caballus	O
CANLF\|Ensembl=ENSCAFG00845020622.1\|UniProtKB=A0A1K0FUE8	Canis lupus familiaris	O
BOVIN\|Ensembl=ENSBTAG00000039056.3\|UniProtKB=E1BIF9	Bos taurus	O
PIG\|Gene=HBT_PIG\|UniProtKB=P04246	Sus scrofa	O
PIG\|Gene=HBE1\|UniProtKB=P02101	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000014726.5\|UniProtKB=F1RII6	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000059175.1\|UniProtKB=F6RF57	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000038029.3\|UniProtKB=A0A2I2U6J8	Felis catus	O
MONDO\|Ensembl=ENSMODG00000011306.3\|UniProtKB=F6WYU4	Monodelphis domestica	O
MONDO\|Ensembl=ENSMODG00000011325.4\|UniProtKB=F6WII6	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000049640.1\|UniProtKB=A0A6I8PBU0	Ornithorhynchus anatinus	O
ORNAN\|Gene=HBB\|UniProtKB=P02111	Ornithorhynchus anatinus	O
ORNAN\|Ensembl=ENSOANG00000043521.1\|UniProtKB=A0A6I8P156	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00015003366\|UniProtKB=P02128	Gallus gallus	O
CHICK\|Gene=HBRH_CHICK\|UniProtKB=P02127	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010003363.1\|UniProtKB=A0A8V0XG92	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010003868\|UniProtKB=P02112	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000012173.3\|UniProtKB=H9GIN1	Anolis carolinensis	O
XENLA\|Gene=HBBL_XENLA\|UniProtKB=P02137	Xenopus laevis	O
XENLA\|Gene=LOC108701506\|UniProtKB=A0A1L8EXA4	Xenopus laevis	O
XENLA\|Gene=hbe1.L\|UniProtKB=Q66KY4	Xenopus laevis	O
XENLA\|Gene=LOC108702417\|UniProtKB=A0A1L8EQ81	Xenopus laevis	O
XENLA\|Gene=LOC108702418\|UniProtKB=A0A1L8EQ40	Xenopus laevis	O
XENTR\|Gene=LOC101735171\|UniProtKB=A0A8J0R500	Xenopus tropicalis	O
XENTR\|Xenbase=XB-GENE-5745824\|UniProtKB=B0BMS6	Xenopus tropicalis	O
XENTR\|Xenbase=XB-GENE-5722135\|UniProtKB=P08423	Xenopus tropicalis	O
XENLA\|Gene=hbg2.S\|UniProtKB=Q6DKM5	Xenopus laevis	O
XENLA\|Gene=hbb1\|UniProtKB=P02132	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-5912896\|UniProtKB=P07429	Xenopus tropicalis	O
XENLA\|Gene=hbb2\|UniProtKB=P02133	Xenopus laevis	O
XENLA\|Gene=LOC108703093\|UniProtKB=A0A1L8EQ32	Xenopus laevis	O
XENLA\|Gene=LOC108703094\|UniProtKB=A0A1L8EQ13	Xenopus laevis	O
XENLA\|Gene=XB5745823.L\|UniProtKB=A2VDC3	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-5808005\|UniProtKB=Q6DJ70	Xenopus tropicalis	O
XENTR\|Gene=LOC100216007\|UniProtKB=B0JZZ3	Xenopus tropicalis	O
XENTR\|Ensembl=ENSXETG00000045178\|UniProtKB=A0A5G3HUQ0	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000005283.2\|UniProtKB=H2LKV1	Oryzias latipes	LDO
LEPOC\|Ensembl=ENSLOCG00000007843.1\|UniProtKB=W5MMA8	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000007787.1\|UniProtKB=W5MM40	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000007827.1\|UniProtKB=W5MM94	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000007852.1\|UniProtKB=W5MMC3	lepisosteus oculatus	O