PANTHER Gene Information

Gene Symbol(s):

GEM

Organism:

Danio rerio

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Gene Name:

GTP-binding protein GEM

Gene ID:

ZDB-GENE-060825-251

Protein ID:

Q0P4E7

Persistent Id:

PTN000632387

Alternate Ids:

ENSDARP00000048035(Ensembl_PRO)	113951749(GI)
ENSDARG00000029112(Ensembl)	BX511010(EMBL)
ENSDART00000048036(Ensembl_TRS)	AAI22114(EMBL-CDS)
Q0P4E7_DANRE(UniProtKB-ID)	NP_001039314(refSeq)
560566(GeneID)	Q0P4E7(Synonym)
ZDB-GENE-060825-251(ZFIN)
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PANTHER Classification

PANTHER Family:	RAD, GEM/KIR FAMILY MEMBER 2, ISOFORM C (PTHR45775)
PANTHER Subfamily:	GTP-BINDING PROTEIN GEM (PTHR45775:SF4)
PANTHER GO-slim Molecular Function:	channel regulator activity carbohydrate derivative binding anion binding nucleotide binding
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:	plasma membrane
PANTHER protein class:

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	nucleotide binding, GTP binding, calmodulin binding, GTPase activity, calcium channel regulator activity
GO BP Complete:	negative regulation of high voltage-gated calcium channel activity
GO CC Complete:	plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=4234\|UniProtKB=P55040	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000020426.6\|UniProtKB=H2QWF7	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000013020.3\|UniProtKB=G3RB61	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000062934.1\|UniProtKB=F7AQV4	Macaca mulatta	LDO
MOUSE\|MGI=MGI=99844\|UniProtKB=P55041	Mus musculus	LDO
RAT\|RGD=1307386\|UniProtKB=B5DFA6	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000007596.5\|UniProtKB=A4IFA1	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000006105.6\|UniProtKB=A0A4X1U6D0	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000018531.3\|UniProtKB=A0A9L0SUQ3	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000015511.5\|UniProtKB=A0A2I2UE29	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845014817.1\|UniProtKB=A0A8I3NVP2	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000007348.4\|UniProtKB=F7B0E6	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000046330.1\|UniProtKB=A0A6I8NQ22	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010012200.1\|UniProtKB=A0A8V0YLJ9	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000003654.3\|UniProtKB=G1KC41	Anolis carolinensis	LDO
XENLA\|Gene=gem.S\|UniProtKB=A0A1L8FTH2	Xenopus laevis	O
XENLA\|Gene=gem.L\|UniProtKB=A0A1L8FZH7	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-483370\|UniProtKB=F7CID2	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000008896.2\|UniProtKB=H2LYE5	Oryzias latipes	LDO
LEPOC\|Ensembl=ENSLOCG00000010118.1\|UniProtKB=W5MVG9	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000024074.1\|UniProtKB=H2XPR0	Ciona intestinalis	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_275554\|UniProtKB=C3ZBL7	Branchiostoma floridae	O
BRAFL\|Gene=LOC118417190\|UniProtKB=A0A9J7L986	Branchiostoma floridae	O
BRAFL\|Gene=LOC118411293\|UniProtKB=A0A9J7MJN1	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC580155\|UniProtKB=A0A7M7RDY9	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00017637\|UniProtKB=P90840	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00032467\|UniProtKB=A8XD93	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00021027\|UniProtKB=Q9TZE3	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG22069\|UniProtKB=A8Y1G6	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00112177\|UniProtKB=A0A2A6B8C7	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00013124\|UniProtKB=Q9U254	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00029881\|UniProtKB=A8X5K3	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00095293\|UniProtKB=A0A2A6BMY8	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0085426\|UniProtKB=A0A076NAB7	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP005243\|UniProtKB=Q7Q9G7	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC032368\|UniProtKB=A0A139WKZ9	Tribolium castaneum	O
DROME\|FlyBase=FBgn0264753\|UniProtKB=A1ZBJ6	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP029465\|UniProtKB=A0A453YZI7	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC008856\|UniProtKB=D6WQS8	Tribolium castaneum	O
DROME\|FlyBase=FBgn0260658\|UniProtKB=Q7KVX6	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0085419\|UniProtKB=A0A0B4LFV4	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP007615\|UniProtKB=Q7QJQ5	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC009270\|UniProtKB=D6WSB6	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_309900\|UniProtKB=E9FR42	Daphnia pulex	O
DAPPU\|Gene_ORFName=DAPPUDRAFT_56406\|UniProtKB=E9GZQ3	Daphnia pulex	O
HELRO\|EnsemblGenome=HelroG105504\|UniProtKB=T1EDW0	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG172362\|UniProtKB=T1F583	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG122480\|UniProtKB=T1EGU7	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG163986\|UniProtKB=T1EUQ3	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG192676\|UniProtKB=T1FU65	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG180180\|UniProtKB=T1FFJ7	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG67160\|UniProtKB=T1FYX5	helobdella robusta	O
CHLRE\|EnsemblGenome=CHLRE_12g553850v5\|UniProtKB=A0A2K3D5Y2	Chlamydomonas reinhardtii	O