PANTHER Gene Information

Gene Symbol(s):

zgc:158858

Organism:

Danio rerio

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Gene Name:

DNA-(apurinic or apyrimidinic site) lyase

Gene ID:

ZDB-GENE-070112-932

Protein ID:

A0A8N7V0N6

Persistent Id:

PTN000028455

Alternate Ids:

NM_001123308(refSeq)	ENSDARP00000078516(Ensembl_PRO)
AL935148(EMBL)	181339906(GI)
791194(GeneID)	ENSDARG00000060002(Ensembl)
ENSDART00000084081(Ensembl_TRS)	A0A8N7V0N6(Synonym)
ZDB-GENE-070112-932(ZFIN)	A0A8N7V0N6_DANRE(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	8-OXOGUANINE DNA GLYCOSYLASE (PTHR10242)
PANTHER Subfamily:	N-GLYCOSYLASE_DNA LYASE (PTHR10242:SF2)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	DNA metabolism protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	catalytic activity, lyase activity, 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity, damaged DNA binding, class I DNA-(apurinic or apyrimidinic site) endonuclease activity, oxidized purine nucleobase lesion DNA N-glycosylase activity
GO BP Complete:	heart rudiment development, DNA repair, base-excision repair, base-excision repair, AP site formation, cardiac muscle cell development, nucleotide-excision repair, brain development, regulation of neuron projection development, DNA damage response, negative regulation of neuron apoptotic process
GO CC Complete:	nucleus

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=8125\|UniProtKB=O15527	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000014593.7\|UniProtKB=H2QM07	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000014259.3\|UniProtKB=G3RZB6	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000006117.4\|UniProtKB=A0A5F8AEV4	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1097693\|UniProtKB=O08760	Mus musculus	LDO
RAT\|RGD=621168\|UniProtKB=O70249	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000007777.6\|UniProtKB=F1MPV2	Bos taurus	LDO
HORSE\|Ensembl=ENSECAG00000010671.4\|UniProtKB=F6T0J0	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000014192.5\|UniProtKB=M3WK92	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845009193.1\|UniProtKB=A0A8I3RV29	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000005099.2\|UniProtKB=F6ZEE7	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000045738.1\|UniProtKB=A0A6I8PGM6	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010021546.1\|UniProtKB=A0A8V0ZD54	Gallus gallus	LDO
XENLA\|Gene=ogg1.L\|UniProtKB=A0A1L8GPW8	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-995809\|UniProtKB=A0A8J0R4E2	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000010758.2\|UniProtKB=H2M4W6	Oryzias latipes	LDO
LEPOC\|Ensembl=ENSLOCG00000014515.1\|UniProtKB=W5NB54	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000010918.3\|UniProtKB=F6TL19	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118421332\|UniProtKB=A0A9J7LK99	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC586897\|UniProtKB=A0A7M7PME8	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105438678\|UniProtKB=A0A7M7NQL3	Strongylocentrotus purpuratus	LDO
PRIPA\|EnsemblGenome=WBGene00275381\|UniProtKB=A0A2A6BER4	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0027864\|UniProtKB=Q9V3I8	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP001854\|UniProtKB=Q7PYB2	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC009047\|UniProtKB=D6WPN3	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_313422\|UniProtKB=E9G475	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW010948\|UniProtKB=B7Q8B3	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG194432\|UniProtKB=T1FW18	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g149802\|UniProtKB=A7T872	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g212141\|UniProtKB=A7SGZ3	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG5178\|UniProtKB=B3RRH5	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_28428\|UniProtKB=A9V852	Monosiga brevicollis	LDO
YEAST\|SGD=S000004525\|UniProtKB=P53397	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AER127C\|UniProtKB=Q756Y7	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000183658\|UniProtKB=A0A1D8PRH2	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_B12870g\|UniProtKB=Q6CEU4	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_06682\|UniProtKB=Q5AYE8	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_7G05320\|UniProtKB=Q4WGK2	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU03040\|UniProtKB=Q7SDG8	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_02978\|UniProtKB=A7ECD9	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_04460\|UniProtKB=Q0UUV4	Phaeosphaeria nodorum	LDO
SCHJY\|EnsemblGenome=SJAG_01119\|UniProtKB=B6JZT0	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNB02890\|UniProtKB=Q5KM54	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_01304\|UniProtKB=A0A0D1E787	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_11243\|UniProtKB=E3KL99	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_89698\|UniProtKB=F4P6D4	Batrachochytrium dendrobatidis	LDO
DICDI\|dictyBase=DDB_G0292618\|UniProtKB=Q54CZ3	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_148999\|UniProtKB=F0ZCJ6	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_34_2170\|UniProtKB=Q4Q2Y3	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb927.4.2480\|UniProtKB=Q584D9	Trypanosoma brucei	LDO
PLAF7\|EnsemblGenome=PF3D7_0917100\|UniProtKB=Q8I2Y2	Plasmodium falciparum	LDO
THAPS\|EnsemblGenome=THAPS_17262\|UniProtKB=B5YNS8	Thalassiosira pseudonana	LDO
CHLRE\|EnsemblGenome=CHLRE_01g063632v5\|UniProtKB=A0A2K3E8G5	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00038p00020700\|UniProtKB=U5CX36	Amborella trichopoda	O
MUSAM\|EnsemblGenome=Ma10_g06570\|UniProtKB=A0A804KTB2	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_029778mg\|UniProtKB=K3ZT48	Setaria italica	O
ORYSJ\|EnsemblGenome=Os07g0657600\|UniProtKB=A0A0P0X9V3	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_1g19145v3\|UniProtKB=I1GRL6	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.2HG0117270\|UniProtKB=A0A8I6X361	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS2A02G132400\|UniProtKB=A0A3B6AU32	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2B02G155000\|UniProtKB=A0A3B6C168	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2D02G134400\|UniProtKB=A0A3B6D8H1	Triticum aestivum	O
NELNU\|Gene=LOC104590857\|UniProtKB=A0A1U7Z9Z7	Nelumbo nucifera	O
SPIOL\|Gene=LOC110776020\|UniProtKB=A0A9R0HSN4	Spinacia oleracea	O
HELAN\|EnsemblGenome=HanXRQr2_Chr12g0557941\|UniProtKB=A0A251T473	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr12g0564821\|UniProtKB=A0A251T5V7	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C800454660\|UniProtKB=A0A9R1UWW6	Lactuca sativa	O
CAPAN\|EnsemblGenome=T459_04345\|UniProtKB=A0A2G3A4S0	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400014526\|UniProtKB=M1B5N8	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc02g005310.2\|UniProtKB=A0A3Q7EV45	Solanum lycopersicum	O
TOBAC\|Gene=LOC107803160\|UniProtKB=A0A1S4B0B8	Nicotiana tabacum	O
VITVI\|Gene_OrderedLocusName=VIT_17s0053g01030\|UniProtKB=D7TXU0	Vitis vinifera	O
BRACM\|EnsemblGenome=Bra038582\|UniProtKB=M4FBW6	Brassica campestris	O
GOSHI\|Gene=LOC107890185\|UniProtKB=A0A1U8I3A4	Gossypium hirsutum	O
GOSHI\|Gene=LOC107941122\|UniProtKB=A0A1U8MTH5	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_033523\|UniProtKB=A0A061FC08	Theobroma cacao	O
MANES\|EnsemblGenome=MANES_18G143000\|UniProtKB=A0A2C9U352	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_18G143300\|UniProtKB=A0A2C9U3H1	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_1564040\|UniProtKB=B9RKX5	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_13G026000\|UniProtKB=A0A0R0GHG3	Glycine max	O
PRUPE\|EnsemblGenome=PRUPE_4G287800\|UniProtKB=A0A251PSM7	Prunus persica	O
NELNU\|Gene_ORFName=HUJ06_013104\|UniProtKB=A0A1U7ZTI4	Nelumbo nucifera	O
SPIOL\|Gene=LOC110789165\|UniProtKB=A0A9R0IHY9	Spinacia oleracea	O
HELAN\|EnsemblGenome=HanXRQr2_Chr15g0711071\|UniProtKB=A0A251SB02	Helianthus annuus	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a019757mg\|UniProtKB=A0A022R075	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_33947\|UniProtKB=A0A2G2XXG3	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400018222\|UniProtKB=M1BJV2	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc01g102670.3\|UniProtKB=A0A3Q7EPQ0	Solanum lycopersicum	O
TOBAC\|Gene=LOC107811584\|UniProtKB=A0A1S4BTA6	Nicotiana tabacum	O
TOBAC\|Gene=LOC107828151\|UniProtKB=A0A1S4DCG1	Nicotiana tabacum	O
EUCGR\|EnsemblGenome=EUGRSUZ_B01586\|UniProtKB=A0A059D212	Eucalyptus grandis	O
EUCGR\|EnsemblGenome=EUGRSUZ_B01611\|UniProtKB=A0A059D242	Eucalyptus grandis	O
EUCGR\|EnsemblGenome=EUGRSUZ_G00036\|UniProtKB=A0A059B945	Eucalyptus grandis	O
GOSHI\|Gene=LOC107943962\|UniProtKB=A0A1U8N5Y6	Gossypium hirsutum	O
GOSHI\|Gene=LOC107906457\|UniProtKB=A0A1U8JJT5	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_027210\|UniProtKB=A0A061G8U0	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g014334mg\|UniProtKB=A0A067EF98	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_003G046300v3\|UniProtKB=A0A2K2B1I8	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_06G015900\|UniProtKB=A0A2C9VLX3	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_1299400\|UniProtKB=B9S065	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_09G018700\|UniProtKB=I1L092	Glycine max	O
JUGRE\|Gene=LOC109008548\|UniProtKB=A0A6P9E7Q6	Juglans regia	O
KLENI\|Gene_ORFName=KFL_005630070\|UniProtKB=A0A1Y1IG31	Klebsormidium nitens	O
AMBTC\|EnsemblGenome=AMTR_s00054p00127440\|UniProtKB=U5DCM7	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_3G00580\|UniProtKB=A0A0K9P3N0	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma11_g10450\|UniProtKB=A0A804L6D6	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_017343mg\|UniProtKB=K3YSU8	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3004G175300\|UniProtKB=C5XU78	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb243580\|UniProtKB=B4FY38	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os02g0552600\|UniProtKB=A0A0P0VKE7	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_3g45690v3\|UniProtKB=I1IAG9	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.3HG0230920\|UniProtKB=A0A8I6XJF7	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS3B02G089300\|UniProtKB=A0A3B6FHH1	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS3D02G075400\|UniProtKB=A0A3B6GNA7	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS3A02G075400\|UniProtKB=A0A3B6EAM3	Triticum aestivum	LDO
NELNU\|Gene=LOC104605795\|UniProtKB=A0A1U8ARL5	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110795030\|UniProtKB=A0A9R0IU73	Spinacia oleracea	LDO
HELAN\|Gene_ORFName=HannXRQ_Chr05g0148721\|UniProtKB=A0A251UQZ9	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C600335080\|UniProtKB=A0A9R1X7T1	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a019943mg\|UniProtKB=A0A022QWX5	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a027124mg\|UniProtKB=A0A022QW05	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_12350\|UniProtKB=A0A2G2ZPN6	Capsicum annuum	O
CAPAN\|EnsemblGenome=T459_12277\|UniProtKB=A0A1U8F6D3	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400009246\|UniProtKB=M1AJ58	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc11g018510.2\|UniProtKB=A0A3Q7JKD2	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107760687\|UniProtKB=A0A1S3X2V4	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi18g00244\|UniProtKB=F6H0J9	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_F03811\|UniProtKB=A0A059BY99	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=GSBRNA2T00125484001\|UniProtKB=A0A078F4Z8	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra017944\|UniProtKB=M4DN57	Brassica campestris	LDO
ARATH\|TAIR=locus=2036957\|UniProtKB=Q9FNY7	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107940555\|UniProtKB=A0A1U8MRM2	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_035166\|UniProtKB=A0A061FPA9	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g020295mg\|UniProtKB=A0A067GLE2	Citrus sinensis	LDO
POPTR\|Gene_ORFName=POPTR_005G180700\|UniProtKB=A0A3N7GG72	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_02G166400\|UniProtKB=A0A251LJ82	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0563200\|UniProtKB=B9S2W7	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_06G115500\|UniProtKB=I1KAC6	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_3g088510\|UniProtKB=G7J4Z8	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr06_03680\|UniProtKB=A0A2I4FY32	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_6G382890\|UniProtKB=A0A0A0KIU8	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_1G492700\|UniProtKB=M5XQI4	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_119537\|UniProtKB=D8SKN7	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_75917\|UniProtKB=D8QPT9	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c15_7530\|UniProtKB=A0A2K1JCC4	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0066s0098\|UniProtKB=A0A2R6WQM6	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_001350090\|UniProtKB=A0A1Y1HWS2	Klebsormidium nitens	LDO
NITMS\|EnsemblGenome=Nmar_1540\|UniProtKB=A9A4Y2	Nitrosopumilus maritimus	LDO
METAC\|EnsemblGenome=MA_3561\|UniProtKB=Q8TK57	Methanosarcina acetivorans	LDO
HALSA\|EnsemblGenome=VNG_1266G\|UniProtKB=Q9HQ94	Halobacterium salinarum	LDO