PANTHER Gene Information

Gene Symbol(s):

zgc:162984

Organism:

Danio rerio

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Gene Name:

DNA-3-methyladenine glycosylase II

Gene ID:

ZDB-GENE-070410-121

Protein ID:

A3KP69

Persistent Id:

PTN000046510

Alternate Ids:

BC134182(EMBL)	AAI34183(EMBL-CDS)
NP_001076319(refSeq)	A3KP69_DANRE(UniProtKB-ID)
ZDB-GENE-070410-121(ZFIN)	A3KP69(Synonym)
130497267(GI)	566516(GeneID)
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PANTHER Classification

PANTHER Family:	DNA-3-METHYLADENINE GLYCOSYLASE (PTHR10429)
PANTHER Subfamily:	DNA-3-METHYLADENINE GLYCOSYLASE (PTHR10429:SF0)
PANTHER GO-slim Molecular Function:	DNA N-glycosylase activity
PANTHER GO-slim Biological Process:	base-excision repair
PANTHER GO-slim Cellular Component:
PANTHER protein class:	DNA glycosylase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	DNA binding, DNA-3-methyladenine glycosylase activity, DNA-7-methylguanine glycosylase activity, catalytic activity, alkylbase DNA N-glycosylase activity, DNA-7-methyladenine glycosylase activity, hydrolase activity, DNA-3-methylguanine glycosylase activity
GO BP Complete:	DNA repair, base-excision repair, DNA damage response
GO CC Complete:	cellular_component

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Resolution of Abasic Sites (AP sites), Base Excision Repair, DNA Repair, Cleavage of the damaged purine, Base-Excision Repair, AP Site Formation, Depurination, Displacement of DNA glycosylase by APEX1

Orthologs

ID	Organism	Type
HUMAN\|HGNC=7211\|UniProtKB=P29372	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000007528.7\|UniProtKB=A0A2I3RCT7	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000010489.3\|UniProtKB=G3R4M1	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000000589.4\|UniProtKB=A0A1D5Q2M4	Macaca mulatta	LDO
MOUSE\|MGI=MGI=97073\|UniProtKB=Q04841	Mus musculus	LDO
RAT\|RGD=3106\|UniProtKB=P23571	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000026422.5\|UniProtKB=F1MKN2	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000007982.5\|UniProtKB=A0A287AUP9	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000022979.4\|UniProtKB=A0A3Q2HEJ7	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000026946.4\|UniProtKB=A0A337RVZ2	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845001219.1\|UniProtKB=A0A8I3MIB3	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000016624.4\|UniProtKB=F6YNB3	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000045811.1\|UniProtKB=A0A6I8NCE3	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010019236.1\|UniProtKB=A0A8V0ZAK6	Gallus gallus	LDO
XENLA\|Gene=mpg.L\|UniProtKB=A0A8J1LVY2	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-6258135\|UniProtKB=A0A6I8SVE4	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000005168.2\|UniProtKB=H2LKG3	Oryzias latipes	LDO
LEPOC\|Ensembl=ENSLOCG00000007699.1\|UniProtKB=W5MLU0	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000012687.2\|UniProtKB=F6U3G5	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118429657\|UniProtKB=A0A9J7M7U2	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC581391\|UniProtKB=A0A7M7REH0	Strongylocentrotus purpuratus	LDO
TRICA\|EnsemblGenome=TC003671\|UniProtKB=D6WDJ3	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_221022\|UniProtKB=E9FUV0	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW002349\|UniProtKB=B7PBB9	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW002350\|UniProtKB=B7PBC0	Ixodes scapularis	LDO
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g84004\|UniProtKB=A7RJS2	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g83847\|UniProtKB=A7RJS4	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG34875\|UniProtKB=B3SF44	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG30689\|UniProtKB=B3S7J5	Trichoplax adhaerens	LDO
TRIV3\|Gene_ORFName=TVAG_489150\|UniProtKB=A2EVC5	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_431800\|UniProtKB=A2F7X7	Trichomonas vaginalis	LDO
PLAF7\|EnsemblGenome=PF3D7_0506300\|UniProtKB=Q8I439	Plasmodium falciparum	O
PLAF7\|EnsemblGenome=PF3D7_1467100\|UniProtKB=Q8IKG6	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00030150001\|UniProtKB=A0BLU9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00031034001\|UniProtKB=A0BQI8	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00029243001\|UniProtKB=A0BI40	Paramecium tetraurelia	LDO
NITMS\|EnsemblGenome=Nmar_1057\|UniProtKB=A9A4H5	Nitrosopumilus maritimus	LDO
KORCO\|EnsemblGenome=Kcr_0745\|UniProtKB=B1L4W4	Korarchaeum cryptofilum	LDO
STRCO\|Gene_OrderedLocusName=SCO1792\|UniProtKB=Q9S208	Streptomyces coelicolor	LDO
MYCTU\|Gene_OrderedLocusName=Rv1688\|UniProtKB=P9WJP7	Mycobacterium tuberculosis	LDO
DEIRA\|EnsemblGenome=DR_2074\|UniProtKB=Q9RSQ0	Deinococcus radiodurans	LDO
GLOVI\|EnsemblGenome=BAC90432\|UniProtKB=Q7NHP4	Gloeobacter violaceus	LDO
BRADU\|EnsemblGenome=BAC49741\|UniProtKB=Q89LR7	Bradyrhizobium diazoefficiens	LDO
COXBU\|EnsemblGenome=CBU_0930\|UniProtKB=Q83D16	Coxiella burnetii	LDO
XANCP\|EnsemblGenome=XCC2316\|UniProtKB=Q8P8C7	Xanthomonas campestris	LDO
PSEAE\|EnsemblGenome=PA4010\|UniProtKB=Q9HX17	Pseudomonas aeruginosa	LDO