PANTHER Gene Information

Gene Symbol(s):

robo2

Organism:

Drosophila melanogaster

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Gene Name:

Roundabout 2, isoform B

Gene ID:

FBgn0002543

Protein ID:

M9PC46

Persistent Id:

PTN000051501

Alternate Ids:

AE014134(EMBL)	NP_001259868(refSeq)
M9PC46_DROME(UniProtKB-ID)	44522(GeneID)
442625177(GI)	FBgn0002543(FlyBase)
FBtr0329985(Ensembl_TRS)	FBpp0303020(Ensembl_PRO)
AGB92405(EMBL-CDS)	M9PC46(Synonym)
FBgn0002543(Ensembl)
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PANTHER Classification

PANTHER Family:	CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN (PTHR12231)
PANTHER Subfamily:	ROUNDABOUT 1, ISOFORM A-RELATED (PTHR12231:SF246)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	immunoglobulin superfamily cell adhesion molecule

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	protein homodimerization activity, axon guidance receptor activity
GO BP Complete:	Roundabout signaling pathway, mushroom body development, regulation of epithelial cell migration, open tracheal system, positive regulation of cell-cell adhesion, outflow tract morphogenesis, salivary gland boundary specification, axon guidance, embryonic heart tube development, cardioblast cell fate specification, synaptic target recognition, ventral cord development, neuron migration, gonad development, central complex development, axon midline choice point recognition, synaptic target inhibition, positive regulation of cell migration
GO CC Complete:	axon

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Role of ABL in ROBO-SLIT signaling, Axon guidance, Regulation of expression of SLITs and ROBOs, Signaling by ROBO receptors, Developmental Biology, Nervous system development

Orthologs

ID	Organism	Type
HUMAN\|HGNC=10249\|UniProtKB=Q9Y6N7	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000015118.7\|UniProtKB=H2RD56	Pan troglodytes	O
MACMU\|Ensembl=ENSMMUG00000002327.4\|UniProtKB=A0A1D5QB17	Macaca mulatta	O
MOUSE\|MGI=MGI=1274781\|UniProtKB=O89026	Mus musculus	O
BOVIN\|Ensembl=ENSBTAG00000009851.7\|UniProtKB=F1N739	Bos taurus	O
MONDO\|Ensembl=ENSMODG00000016857.4\|UniProtKB=A0A5F8G764	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000013804.4\|UniProtKB=F7DL02	Ornithorhynchus anatinus	O
DANRE\|Gene=robo1\|UniProtKB=A0A8M6Z9Z4	Danio rerio	O
MACMU\|Ensembl=ENSMMUG00000021576.4\|UniProtKB=F7ECW3	Macaca mulatta	O
MOUSE\|MGI=MGI=1343102\|UniProtKB=Q9Z2I4	Mus musculus	O
RAT\|RGD=1311018\|UniProtKB=A0A8I6AJI9	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000004355.6\|UniProtKB=E1BE71	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000015202.4\|UniProtKB=F1S796	Sus scrofa	O
MACMU\|Ensembl=ENSMMUG00000012609.4\|UniProtKB=A0A1D5RF65	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1890110\|UniProtKB=Q7TPD3	Mus musculus	LDO
RAT\|RGD=620167\|UniProtKB=F1M950	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000010462.6\|UniProtKB=A0A3Q1MJK7	Bos taurus	LDO
HORSE\|Ensembl=ENSECAG00000010762.4\|UniProtKB=F7BHQ9	Equus caballus	LDO
MONDO\|Ensembl=ENSMODG00000016811.5\|UniProtKB=A0A5F8G2V8	Monodelphis domestica	LDO
DANRE\|Gene=robo2\|UniProtKB=A0A8M9Q0I3	Danio rerio	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_64608\|UniProtKB=E9HNZ5	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_56955\|UniProtKB=E9H0Z5	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_56983\|UniProtKB=E9H0Z2	Daphnia pulex	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g218534\|UniProtKB=A7SWF5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g214434\|UniProtKB=A7SM80	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g216597\|UniProtKB=A7SS35	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g221651\|UniProtKB=A7T347	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g236748\|UniProtKB=A7RYG0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g241045\|UniProtKB=A7RVU5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g241044\|UniProtKB=A7RVU3	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG53319\|UniProtKB=B3RNW8	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG62006\|UniProtKB=B3SCK6	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG55083\|UniProtKB=B3RQR1	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG62466\|UniProtKB=B3SDW1	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG59528\|UniProtKB=B3S5W2	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG62007\|UniProtKB=B3SCK7	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG12078\|UniProtKB=B3RXE3	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG55084\|UniProtKB=B3RQR2	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG59531\|UniProtKB=B3S5W5	Trichoplax adhaerens	O