PANTHER Gene Information

Gene Symbol(s):

Rab18

Organism:

Drosophila melanogaster

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Gene Name:

GH11193p

Gene ID:

FBgn0015794

Protein ID:

Q9W4A0

Persistent Id:

PTN000636381

Alternate Ids:

Q9W4A0_DROME(UniProtKB-ID)	FBgn0015794(Ensembl)
18447210(GI)	NP_524744(refSeq)
AY075329(EMBL)	AAF46057(EMBL-CDS)
FBtr0070849(Ensembl_TRS)	Q9W4A0(Synonym)
FBgn0015794(FlyBase)	FBpp0070814(Ensembl_PRO)
44360(GeneID)
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PANTHER Classification

PANTHER Family:	DRAB5-RELATED (PTHR24073)
PANTHER Subfamily:	RAS-RELATED PROTEIN RAB-18 (PTHR24073:SF285)
PANTHER GO-slim Molecular Function:	GTPase activity
PANTHER GO-slim Biological Process:	intracellular protein transport
PANTHER GO-slim Cellular Component:	Golgi apparatus
PANTHER protein class:	small GTPase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	GTP binding, protein binding, GTPase activity
GO BP Complete:	vesicle-mediated transport, Rab protein signal transduction, lipid droplet organization, intracellular protein transport, macroautophagy
GO CC Complete:	early endosome, endomembrane system, vesicle, endoplasmic reticulum, Golgi apparatus, neuronal cell body, autolysosome, autophagosome

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Immune System, Metabolism of proteins, Golgi-to-ER retrograde transport, RAB geranylgeranylation, Vesicle-mediated transport, Post-translational protein modification, COPI-independent Golgi-to-ER retrograde traffic, Rab regulation of trafficking, RAB GEFs exchange GTP for GDP on RABs, Membrane Trafficking, Innate Immune System, Intra-Golgi and retrograde Golgi-to-ER traffic, Neutrophil degranulation

Orthologs

ID	Organism	Type
HUMAN\|HGNC=14244\|UniProtKB=Q9NP72	Homo sapiens	LDO
MOUSE\|MGI=MGI=102790\|UniProtKB=P35293	Mus musculus	LDO
RAT\|RGD=1308905\|UniProtKB=Q5EB77	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000009871.5\|UniProtKB=A0A452DIB1	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000028655.4\|UniProtKB=I3LC07	Sus scrofa	LDO
FELCA\|Ensembl=ENSFCAG00000027161.4\|UniProtKB=M3WSV9	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845012414.1\|UniProtKB=A0A8I3NLW8	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000008253.3\|UniProtKB=F6ZX76	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000036374.1\|UniProtKB=A0A6I8P127	Ornithorhynchus anatinus	LDO
CHICK\|Gene_ORFName=RCJMB04_6g4\|UniProtKB=Q5ZLG1	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000045420.1\|UniProtKB=A0A803TH47	Anolis carolinensis	LDO
ORYLA\|Ensembl=ENSORLG00000004624.2\|UniProtKB=H2LII7	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000009609.2\|UniProtKB=A0A3B3HA42	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-030131-3980\|UniProtKB=Q6P129	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-040801-185\|UniProtKB=Q6DHC1	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000007491.1\|UniProtKB=W5ML35	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000006838.3\|UniProtKB=A0A1W2WHR9	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118424573\|UniProtKB=A0A9J7LV91	Branchiostoma floridae	LDO
CAEEL\|WormBase=WBGene00004277\|UniProtKB=Q8MXS1	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00035481\|UniProtKB=P90726	Caenorhabditis briggsae	LDO
ANOGA\|EnsemblGenome=AGAP010875\|UniProtKB=Q7QGS6	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC014110\|UniProtKB=D6WKA1	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_301483\|UniProtKB=E9HIT2	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW016507\|UniProtKB=B7P6C7	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG156372\|UniProtKB=T1ELU7	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG161341\|UniProtKB=T1ERD1	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g131020\|UniProtKB=A7STG0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g184492\|UniProtKB=A7S1E6	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG49948\|UniProtKB=B3RQZ5	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_35113\|UniProtKB=A9UX66	Monosiga brevicollis	LDO
YEAST\|SGD=S000005248\|UniProtKB=P48559	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_ADL162W\|UniProtKB=Q75AT2	Eremothecium gossypii	LDO
NEUCR\|EnsemblGenome=NCU01453\|UniProtKB=V5ILV9	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_00196\|UniProtKB=A7E4H4	Sclerotinia sclerotiorum	LDO
USTMA\|EnsemblGenome=UMAG_03602\|UniProtKB=A0A0D1DWB6	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_18502\|UniProtKB=E3L6W2	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_11776\|UniProtKB=E3KM95	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_11061\|UniProtKB=F4P1B0	Batrachochytrium dendrobatidis	LDO
ENTH1\|Gene_ORFName=EHI_005900\|UniProtKB=A0A8U0WQ32	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0289827\|UniProtKB=Q54GY8	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_57208\|UniProtKB=F0ZUW8	Dictyostelium purpureum	LDO
TRIV3\|Gene_ORFName=TVAG_192440\|UniProtKB=A0A8U0WPV4	Trichomonas vaginalis	LDO
PLAF7\|EnsemblGenome=PF3D7_0807300\|UniProtKB=Q7K6B0	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00003269001\|UniProtKB=A0DZ33	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00001436001\|UniProtKB=Q3SDR5	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00034817001\|UniProtKB=A0C3H1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00015561001\|UniProtKB=A0DCB6	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_32223\|UniProtKB=B8BVR9	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3G613_PHYRM\|UniProtKB=H3G613	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_06g278139v5\|UniProtKB=A8J947	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_11g482900v5\|UniProtKB=A8J7A7	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00140p00089630\|UniProtKB=W1P4J7	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_50G01010\|UniProtKB=A0A0K9NY70	Zostera marina	O
MUSAM\|EnsemblGenome=Ma08_g12770\|UniProtKB=A0A804K5Y4	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma11_g15640\|UniProtKB=A0A804L889	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_036575mg\|UniProtKB=K4ACG8	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3001G230900\|UniProtKB=C5WZH6	Sorghum bicolor	O
ORYSJ\|EnsemblGenome=Os10g0456600\|UniProtKB=Q7XDQ3	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_3g27890v3\|UniProtKB=I1I4E6	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.1HG0039740\|UniProtKB=A0A8I6WFF8	Hordeum vulgare subsp. vulgare	O
SETIT\|EnsemblGenome=SETIT_037497mg\|UniProtKB=K4AF40	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3001G505200\|UniProtKB=C5WXZ0	Sorghum bicolor	O
ORYSJ\|EnsemblGenome=Os03g0146000\|UniProtKB=Q10RT8	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_1g75340v3\|UniProtKB=I1H9T0	Brachypodium distachyon	O
HELAN\|EnsemblGenome=HanXRQr2_Chr08g0329551\|UniProtKB=A0A251U3S5	Helianthus annuus	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a026628mg\|UniProtKB=A0A022RI54	Erythranthe guttata	O
TOBAC\|Gene=LOC107819274\|UniProtKB=A0A1S4CIM1	Nicotiana tabacum	O
TOBAC\|Gene=LOC107759889\|UniProtKB=A0A1S3X090	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi13g02070\|UniProtKB=D7TM25	Vitis vinifera	O
THECC\|EnsemblGenome=TCM_043355\|UniProtKB=A0A061FVM1	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g028315mg\|UniProtKB=A0A067E9K2	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_010G229600v3\|UniProtKB=A9P9Z6	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_008G032000v3\|UniProtKB=B9HL69	Populus trichocarpa	O
RICCO\|Gene_ORFName=RCOM_0443140\|UniProtKB=B9T3G9	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_10G197400\|UniProtKB=I1LCM3	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_20G192600\|UniProtKB=K7N4G3	Glycine max	O
MEDTR\|EnsemblGenome=MTR_1g090717\|UniProtKB=B7FF73	Medicago truncatula	O
CUCSA\|EnsemblGenome=Csa_2G326500\|UniProtKB=A0A0A0LN27	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_2G205300\|UniProtKB=M5XDM0	Prunus persica	O
HELAN\|EnsemblGenome=HanXRQr2_Chr02g0076911\|UniProtKB=A0A251U9U5	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr11g0515551\|UniProtKB=A0A251TEQ4	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr13g0585741\|UniProtKB=A0A251SS31	Helianthus annuus	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a013767mg\|UniProtKB=A0A022RNE7	Erythranthe guttata	O
TOBAC\|Gene=LOC107770475\|UniProtKB=A0A1S3XZA4	Nicotiana tabacum	O
TOBAC\|Gene=LOC107810401\|UniProtKB=A0A1S4BP68	Nicotiana tabacum	O
TOBAC\|Gene=LOC107828731\|UniProtKB=A0A1S4DDS5	Nicotiana tabacum	O
TOBAC\|Gene=LOC107801453\|UniProtKB=A0A1S4AUA5	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi08g01596\|UniProtKB=D7TIU1	Vitis vinifera	O
BRACM\|EnsemblGenome=Bra029804\|UniProtKB=A0A3P5ZLE9	Brassica campestris	O
ARATH\|TAIR=locus=2085084\|UniProtKB=Q9SF92	Arabidopsis thaliana	O
BRACM\|EnsemblGenome=Bra028830\|UniProtKB=M4EJ64	Brassica campestris	O
BRACM\|EnsemblGenome=Bra009524\|UniProtKB=M4CZ77	Brassica campestris	O
ARATH\|TAIR=locus=2831859\|UniProtKB=O49841	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107921463\|UniProtKB=A0A1U8KWK5	Gossypium hirsutum	O
GOSHI\|Gene=LOC107898799\|UniProtKB=A0A1U8INY5	Gossypium hirsutum	O
GOSHI\|Gene=LOC107939157\|UniProtKB=A0A1U8MM91	Gossypium hirsutum	O
GOSHI\|Gene=LOC107907324\|UniProtKB=A0A1U8JN65	Gossypium hirsutum	O
GOSHI\|Gene=LOC107899493\|UniProtKB=A0A1U8IRL3	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_022301\|UniProtKB=A0A061ESE3	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g028300mg\|UniProtKB=A0A067DLS1	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_006G121400v3\|UniProtKB=A0A2K2A0Z1	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_016G097800v3\|UniProtKB=B9IFU0	Populus trichocarpa	O
RICCO\|Gene_ORFName=RCOM_1353390\|UniProtKB=B9S0D4	Ricinus communis	O
RICCO\|Gene_ORFName=RCOM_1353380\|UniProtKB=B9S0D3	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_03G186200\|UniProtKB=I1JPS2	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_19G186300\|UniProtKB=I1NAD3	Glycine max	O
MEDTR\|EnsemblGenome=MTR_7g103070\|UniProtKB=I3SIE3	Medicago truncatula	O
SOYBN\|EnsemblGenome=GLYMA_13G146600\|UniProtKB=I1LZA9	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_10G059900\|UniProtKB=A0A0R4J442	Glycine max	O
MEDTR\|EnsemblGenome=MTR_1g062760\|UniProtKB=A0A072VKJ5	Medicago truncatula	O
CUCSA\|EnsemblGenome=Csa_6G016920\|UniProtKB=A0A0A0KAL0	Cucumis sativus	O
CUCSA\|EnsemblGenome=Csa_3G743430\|UniProtKB=A0A0A0LGE4	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_7G125400\|UniProtKB=M5W3D5	Prunus persica	O
AMBTC\|EnsemblGenome=AMTR_s00017p00258370\|UniProtKB=W1PNR5	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_196G00050\|UniProtKB=A0A0K9PNW8	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma07_g03150\|UniProtKB=A0A804JRK9	Musa acuminata subsp. malaccensis	LDO
MUSAM\|EnsemblGenome=Ma02_g02730\|UniProtKB=A0A804HYL4	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_023208mg\|UniProtKB=K3Z9I7	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3006G281800\|UniProtKB=C5YB63	Sorghum bicolor	LDO
BRADI\|EnsemblGenome=BRADI_5g27670v3\|UniProtKB=I1J3W1	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.2HG0217920\|UniProtKB=M0YAR4	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS2B02G617000\|UniProtKB=A0A0C4BJ10	Triticum aestivum	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr05g0235211\|UniProtKB=A0A251UU95	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr15g0704921\|UniProtKB=A0A251SAJ8	Helianthus annuus	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a013810mg\|UniProtKB=A0A022Q7A1	Erythranthe guttata	LDO
TOBAC\|Gene=LOC107762524\|UniProtKB=A0A1S3X8Z4	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi18g01187\|UniProtKB=F6GZU4	Vitis vinifera	LDO
GOSHI\|Gene=LOC107961431\|UniProtKB=A0A1U8PPH1	Gossypium hirsutum	O
GOSHI\|Gene=LOC107935789\|UniProtKB=A0A1U8MAW3	Gossypium hirsutum	O
GOSHI\|Gene=LOC107914429\|UniProtKB=A0A1U8K8L4	Gossypium hirsutum	O
GOSHI\|Gene=LOC107896742\|UniProtKB=A0A1U8IH48	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_001502\|UniProtKB=A0A061DJ31	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g028353mg\|UniProtKB=A0A067ELA4	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_005G063500v3\|UniProtKB=B9H489	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_007G105500v3\|UniProtKB=B9HES5	Populus trichocarpa	O
SOYBN\|EnsemblGenome=GLYMA_06G154000\|UniProtKB=I1KBJ9	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_04G212400\|UniProtKB=I1JY15	Glycine max	O
MEDTR\|EnsemblGenome=MTR_3g096350\|UniProtKB=G7JBL5	Medicago truncatula	O
SOYBN\|EnsemblGenome=GLYMA_06G241100\|UniProtKB=K7KX18	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_05G191800\|UniProtKB=I1K4Z4	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_08G157000\|UniProtKB=A0A0R4J3X0	Glycine max	O
MEDTR\|EnsemblGenome=MTR_8g093740\|UniProtKB=G7LE30	Medicago truncatula	O
CUCSA\|EnsemblGenome=Csa_2G334520\|UniProtKB=A0A0A0LQC6	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_4G271600\|UniProtKB=M5WIZ7	Prunus persica	O
BRACM\|EnsemblGenome=Bra036934\|UniProtKB=M4F774	Brassica campestris	O
BRACM\|EnsemblGenome=Bra034924\|UniProtKB=M4F1H8	Brassica campestris	O
BRACM\|EnsemblGenome=Bra032196\|UniProtKB=A0A397ZBJ3	Brassica campestris	LDO
ARATH\|TAIR=locus=2029167\|UniProtKB=O23657	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107910409\|UniProtKB=A0A1U8JTX6	Gossypium hirsutum	O
GOSHI\|Gene=LOC107951470\|UniProtKB=A0A1U8NSR2	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_035325\|UniProtKB=A0A061FPS0	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g028292mg\|UniProtKB=A0A067GV11	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_002G074400v3\|UniProtKB=A0A2K2BEY7	Populus trichocarpa	LDO
RICCO\|Gene_ORFName=RCOM_0559580\|UniProtKB=B9S2N6	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_13G036800\|UniProtKB=I1LXB2	Glycine max	LDO
SOYBN\|EnsemblGenome=GLYMA_14G118400\|UniProtKB=C6TJB7	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_1g029450\|UniProtKB=A0A072VQS8	Medicago truncatula	LDO
CUCSA\|EnsemblGenome=Csa_6G395140\|UniProtKB=A0A0A0KH59	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_8G013500\|UniProtKB=M5W4G8	Prunus persica	LDO
PHYPA\|EnsemblGenome=Pp3c27_4610\|UniProtKB=A0A2K1IAP8	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c2_19550\|UniProtKB=A9TVJ2	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c10_2770\|UniProtKB=A9S6H2	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c5_3390\|UniProtKB=A9SFA0	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c1_26930\|UniProtKB=A9RPZ8	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c16_12190\|UniProtKB=A9RLA5	Physcomitrella patens	LDO