PANTHER Gene Information

Gene Symbol(s):

Rep

Organism:

Drosophila melanogaster

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Gene Name:

Rab proteins geranylgeranyltransferase component A

Gene ID:

FBgn0026378

Protein ID:

Q9V8W3

Persistent Id:

PTN000209606

Alternate Ids:

AAD16891(EMBL-CDS)	AE013599(EMBL)
37246(GeneID)	RABEP_DROME(UniProtKB-ID)
FBpp0085658(Ensembl_PRO)	FBgn0026378(FlyBase)
O97142(AltAccession)	REP(Synonym)
17137652(GI)	NM_058072(refSeq)
Rep{ECO:0000312\|FlyBase:FBgn0026378}(Symbol)	FBgn0026378(Ensembl)
FBtr0086462(Ensembl_TRS)
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PANTHER Classification

PANTHER Family:	RAB GDP-DISSOCIATION INHIBITOR (PTHR11787)
PANTHER Subfamily:	CHM, RAB ESCORT PROTEIN 1 (PTHR11787:SF4)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	protein modification process vesicle-mediated transport cellular metabolic process
PANTHER GO-slim Cellular Component:	transferase complex nucleus cytosol
PANTHER protein class:	G-protein modulator

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	GDP-dissociation inhibitor activity
GO BP Complete:	positive regulation of protein localization to endoplasmic reticulum, vesicle-mediated transport, small GTPase-mediated signal transduction, protein geranylgeranylation, intracellular protein transport, neurotransmitter secretion
GO CC Complete:	nucleus, perinuclear region of cytoplasm, cytoplasm, Rab-protein geranylgeranyltransferase complex, synaptic vesicle, membrane, spindle pole, aster, cytosol

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Generic Transcription Pathway, Transcriptional Regulation by TP53, Metabolism of proteins, Gene expression (Transcription), RAB geranylgeranylation, TP53 Regulates Transcription of Cell Death Genes, TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain, Vesicle-mediated transport, Post-translational protein modification, Rab regulation of trafficking, RAB GEFs exchange GTP for GDP on RABs, Membrane Trafficking, RNA Polymerase II Transcription

Orthologs

ID	Organism	Type
HUMAN\|HGNC=1940\|UniProtKB=P24386	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000022071.7\|UniProtKB=H2QYV2	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000022912.2\|UniProtKB=G3RQ74	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000016776.4\|UniProtKB=G7NSD9	Macaca mulatta	LDO
MOUSE\|MGI=MGI=892979\|UniProtKB=Q9QXG2	Mus musculus	LDO
RAT\|RGD=2340\|UniProtKB=P37727	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000009598.6\|UniProtKB=F1MS24	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000012463.6\|UniProtKB=K7GL59	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000019201.4\|UniProtKB=F7A2B6	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000030652.4\|UniProtKB=M3X8J0	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845024883.1\|UniProtKB=A0A8I3PPC3	Canis lupus familiaris	LDO
HUMAN\|HGNC=1941\|UniProtKB=P26374	Homo sapiens	O
GORGO\|Ensembl=ENSGGOG00000016322.3\|UniProtKB=A0A2I2YJW8	Gorilla gorilla gorilla	O
MOUSE\|MGI=MGI=101913\|UniProtKB=Q9QZD5	Mus musculus	O
RAT\|RGD=1596201\|UniProtKB=A0A8I6AAJ7	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000010803.6\|UniProtKB=F1N2I0	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000031212.2\|UniProtKB=A0A286ZPQ2	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000049917.1\|UniProtKB=A0A9L0S7I9	Equus caballus	O
CANLF\|Ensembl=ENSCAFG00845004391.1\|UniProtKB=A0A8I3MQ21	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000014364.4\|UniProtKB=F6TPE3	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000007635.3\|UniProtKB=A0A6I8NJL7	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010018244.1\|UniProtKB=A0A8V0YYT2	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000013859.4\|UniProtKB=H9GKI1	Anolis carolinensis	LDO
XENLA\|Gene=chm.S\|UniProtKB=A0A1L8F350	Xenopus laevis	O
XENLA\|Gene=chm.L\|UniProtKB=Q6P7I1	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-956389\|UniProtKB=A0A6I8R688	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000012940.2\|UniProtKB=H2MCD7	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-030318-2\|UniProtKB=Q6RFG0	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000014266.1\|UniProtKB=W5NAA7	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000011466.2\|UniProtKB=H2XMQ8	Ciona intestinalis	LDO
BRAFL\|Gene_ORFName=BRAFLDRAFT_123298\|UniProtKB=C3YZ95	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC100891770\|UniProtKB=A0A7M7PUA3	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00022051\|UniProtKB=Q9BKQ5	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG15217\|UniProtKB=A8XLN1	Caenorhabditis briggsae	LDO
ANOGA\|EnsemblGenome=AGAP012773\|UniProtKB=Q7QL77	Anopheles gambiae	LDO
ANOGA\|EnsemblGenome=AGAP010419\|UniProtKB=Q7QDU2	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC007846\|UniProtKB=D2A2F3	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_329332\|UniProtKB=E9HGA5	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW023023\|UniProtKB=B7QIZ6	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG191009\|UniProtKB=T1FSH8	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g80158\|UniProtKB=A7RFZ7	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG63951\|UniProtKB=B3RY88	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_28367\|UniProtKB=A9V7Z0	Monosiga brevicollis	LDO
YEAST\|SGD=S000005897\|UniProtKB=P32864	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_ADR413C\|UniProtKB=Q758W5	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000176006\|UniProtKB=Q5ADQ8	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_F06116g\|UniProtKB=Q6C2P8	Yarrowia lipolytica	LDO
ASPFU\|EnsemblGenome=AFUA_6G02130\|UniProtKB=Q4WCR2	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU03191\|UniProtKB=Q7SGX8	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_05415\|UniProtKB=A7EJC2	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_07680\|UniProtKB=Q0UKN4	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPBC15C4.03\|UniProtKB=O60112	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_02063\|UniProtKB=B6JZM0	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNC01590\|UniProtKB=Q5KKW8	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_10571\|UniProtKB=A0A0D1E1H8	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_08843\|UniProtKB=E3KEB4	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_35555\|UniProtKB=F4P7C0	Batrachochytrium dendrobatidis	LDO
DICDI\|dictyBase=DDB_G0280143\|UniProtKB=Q54VT9	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_98103\|UniProtKB=F0ZMQ2	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_15_0820\|UniProtKB=Q4QFA2	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb09.160.4680\|UniProtKB=Q38ET8	Trypanosoma brucei	LDO
TRIV3\|Gene_ORFName=TVAG_156040\|UniProtKB=A2FPC7	Trichomonas vaginalis	LDO
PARTE\|EnsemblGenome=GSPATT00036677001\|UniProtKB=A0CAS9	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_2415\|UniProtKB=B8BUA8	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GGP8_PHYRM\|UniProtKB=H3GGP8	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_10g425550v5\|UniProtKB=A0A2K3D9H1	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00022p00049680\|UniProtKB=W1PUB9	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_15G01430\|UniProtKB=A0A0K9PV33	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma06_g04990\|UniProtKB=A0A804JCS3	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_026180mg\|UniProtKB=K3ZHX8	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3003G126600\|UniProtKB=A0A1B6Q2T8	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb333020\|UniProtKB=A0A804QIZ9	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb128670\|UniProtKB=A0A1D6MQK0	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os01g0269100\|UniProtKB=Q0JNR7	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_5g12704v3\|UniProtKB=A0A2K2CGV1	Brachypodium distachyon	O
BRADI\|EnsemblGenome=BRADI_4g00510v3\|UniProtKB=A0A0Q3HBY0	Brachypodium distachyon	O
BRADI\|EnsemblGenome=BRADI_2g10117v3\|UniProtKB=A0A0Q3MHB4	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.3HG0256150\|UniProtKB=M0UFX3	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS3B02G215300\|UniProtKB=A0A077RZY9	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3A02G185700\|UniProtKB=A0A3B6EEC8	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3D02G189700\|UniProtKB=A0A3B6GS68	Triticum aestivum	LDO
NELNU\|Gene=LOC104591446\|UniProtKB=A0A1U7ZL33	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110803177\|UniProtKB=A0A9R0JAR3	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr14g0644001\|UniProtKB=A0A251SIP8	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C200076990\|UniProtKB=A0A9R1WCX4	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a004151mg\|UniProtKB=A0A022Q5F0	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_06080\|UniProtKB=A0A1U8FMC4	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG401001521\|UniProtKB=M0ZMF0	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc02g082730.3\|UniProtKB=A0A3Q7F6B2	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107802495\|UniProtKB=A0A1S4AY66	Nicotiana tabacum	O
TOBAC\|Gene=LOC107763638\|UniProtKB=A0A1S3XCI2	Nicotiana tabacum	O
TOBAC\|Gene=LOC107778289\|UniProtKB=A0A1S3YPG9	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi04g01571\|UniProtKB=D7U473	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_I02226\|UniProtKB=A0A059ARP3	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=GSBRNA2T00057529001\|UniProtKB=A0A078HB02	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00027065001\|UniProtKB=A0A078GHA6	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra029586\|UniProtKB=M4ELB8	Brassica campestris	LDO
ARATH\|TAIR=locus=2084289\|UniProtKB=Q8LLD4	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107955087\|UniProtKB=A0A1U8P7M4	Gossypium hirsutum	O
GOSHI\|Gene=LOC107955621\|UniProtKB=A0A1U8P9E0	Gossypium hirsutum	O
GOSHI\|Gene=LOC107886662\|UniProtKB=A0A1U8HJG2	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_000070\|UniProtKB=A0A061DF33	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g009240mg\|UniProtKB=A0A067FVN3	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_005G101100v3\|UniProtKB=A0A2K2AEL1	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_005G030000v3\|UniProtKB=A0A2K2AAW2	Populus trichocarpa	LDO
POPTR\|EnsemblGenome=POPTR_005G028900v3\|UniProtKB=A0A2K2AAU5	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_01G155100\|UniProtKB=A0A2C9WNF0	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0874210\|UniProtKB=B9S6U7	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_11G085700\|UniProtKB=I1LIA8	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_01G159000\|UniProtKB=I1J8C9	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_5g025170\|UniProtKB=G7K2P9	Medicago truncatula	O
MEDTR\|EnsemblGenome=MTR_5g024150\|UniProtKB=G7K177	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr16_03710\|UniProtKB=A0A2I4DZF4	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_3G001770\|UniProtKB=A0A0A0L0Y1	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_6G331900\|UniProtKB=A0A251NZ93	Prunus persica	O
PRUPE\|EnsemblGenome=PRUPE_7G181700\|UniProtKB=M5VXF3	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_96262\|UniProtKB=D8RLA6	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_106997\|UniProtKB=D8S2P8	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c12_25630\|UniProtKB=A0A2K1JS69	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0007s0130\|UniProtKB=A0A2R6XNP3	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_004120100\|UniProtKB=A0A1Y1ICD1	Klebsormidium nitens	LDO