PANTHER Gene Information

Gene Symbol(s):

SPARC

Organism:

Drosophila melanogaster

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Gene Name:

BM-40

Gene ID:

FBgn0026562

Protein ID:

O97365

Persistent Id:

PTN000355783

Alternate Ids:

NM_143252(refSeq)	O97365(Synonym)
AAF56632(EMBL-CDS)	O97365_DROME(UniProtKB-ID)
FBtr0334309(Ensembl_TRS)	BT128781(EMBL)
FBgn0026562(FlyBase)	FBpp0084464(Ensembl_PRO)
10726793(GI)	43230(GeneID)
FBgn0026562(Ensembl)
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PANTHER Classification

PANTHER Family:	SPARC OSTEONECTIN (PTHR13866)
PANTHER Subfamily:	BM-40 (PTHR13866:SF14)
PANTHER GO-slim Molecular Function:	calcium ion binding extracellular matrix binding collagen binding
PANTHER GO-slim Biological Process:	anatomical structure development
PANTHER GO-slim Cellular Component:	extracellular space
PANTHER protein class:	extracellular matrix glycoprotein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	extracellular matrix binding, collagen binding, calcium ion binding
GO BP Complete:	larval feeding behavior, larval fat body development, Malpighian tubule morphogenesis, mesoderm development, trachea development, basement membrane assembly, cell adhesion, extracellular matrix constituent secretion, anterior Malpighian tubule development
GO CC Complete:	extracellular space, collagen-containing extracellular matrix, extracellular matrix

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Response to elevated platelet cytosolic Ca2+, Post-translational protein phosphorylation, Platelet degranulation , Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs), Hemostasis, Metabolism of proteins, Platelet activation, signaling and aggregation, Post-translational protein modification

Orthologs

ID	Organism	Type
ORYLA\|Ensembl=ENSORLG00000026981.1\|UniProtKB=A0A3B3I1E6	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-131127-575\|UniProtKB=X1WD35	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000012446.1\|UniProtKB=W5N3W2	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000002369.3\|UniProtKB=F6R501	Ciona intestinalis	O
BRAFL\|Gene=LOC118411009\|UniProtKB=A0A9J7KR88	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC581509\|UniProtKB=A0A7M7TGR8	Strongylocentrotus purpuratus	O
HUMAN\|HGNC=13564\|UniProtKB=Q92563	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000002608.5\|UniProtKB=A0A2J8NUP4	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000023784.2\|UniProtKB=G3RTX3	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000002122.4\|UniProtKB=F6UWN5	Macaca mulatta	O
MOUSE\|MGI=MGI=1891351\|UniProtKB=Q9ER58	Mus musculus	O
RAT\|RGD=1308568\|UniProtKB=A0A0G2K946	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000008827.6\|UniProtKB=A0A3Q1M718	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000010283.5\|UniProtKB=A0A8W4FC70	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000009278.4\|UniProtKB=F6YRQ9	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000013054.6\|UniProtKB=M3WI49	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845004641.1\|UniProtKB=A0A8I3N9C0	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000000012.4\|UniProtKB=A0A5F8GD77	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000011747.4\|UniProtKB=F6TWI2	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010021659.1\|UniProtKB=A0A8V0ZJH8	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000001348.4\|UniProtKB=G1K9F3	Anolis carolinensis	O
XENLA\|Gene=spock2.L\|UniProtKB=A0A1L8FJY7	Xenopus laevis	O
XENLA\|Gene=spock2.S\|UniProtKB=Q6GLM8	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-1003767\|UniProtKB=A0A803JQ85	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000006790.2\|UniProtKB=H2LR33	Oryzias latipes	O
DANRE\|Gene=spock2\|UniProtKB=A0A8M1RM78	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000005246.1\|UniProtKB=W5MD62	lepisosteus oculatus	O
HUMAN\|HGNC=11251\|UniProtKB=Q08629	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000017270.4\|UniProtKB=H2QRJ5	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000000808.4\|UniProtKB=G3QEU5	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000001344.4\|UniProtKB=F7B8Z2	Macaca mulatta	O
MOUSE\|MGI=MGI=105371\|UniProtKB=Q62288	Mus musculus	O
PIG\|Ensembl=ENSSSCG00000032423.3\|UniProtKB=A0A286ZS89	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000007511.4\|UniProtKB=A0A9L0RP19	Equus caballus	O
CANLF\|Ensembl=ENSCAFG00845016123.1\|UniProtKB=A0A8I3P7M1	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000046877.1\|UniProtKB=A0A5F8GWM9	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000045148.1\|UniProtKB=A0A6I8N9Z9	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010015776.1\|UniProtKB=A0A8V0YV23	Gallus gallus	O
DANRE\|ZFIN=ZDB-GENE-110428-1\|UniProtKB=E7F9M2	Danio rerio	O
HUMAN\|HGNC=13565\|UniProtKB=Q9BQ16	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000016579.6\|UniProtKB=A0A2I3RAD1	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000036722.1\|UniProtKB=A0A2I2Y220	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000006851.4\|UniProtKB=F7FCP3	Macaca mulatta	O
MOUSE\|MGI=MGI=1920152\|UniProtKB=Q8BKV0	Mus musculus	O
RAT\|RGD=1305672\|UniProtKB=A0A8I6AMA2	Rattus norvegicus	O
PIG\|Ensembl=ENSSSCG00000009722.5\|UniProtKB=F1RIW2	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000024906.4\|UniProtKB=A0A5F5PQP0	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000031122.4\|UniProtKB=M3WZA2	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845007714.1\|UniProtKB=A0A8I3N597	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000002474.4\|UniProtKB=A0A5F8HID6	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000014484.3\|UniProtKB=A0A6I8P250	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010008036.1\|UniProtKB=A0A8V0XXJ7	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000016126.4\|UniProtKB=A0A803TFJ0	Anolis carolinensis	O
XENLA\|Gene=LOC108704954\|UniProtKB=A0A8J1MTN0	Xenopus laevis	O
XENLA\|Gene=LOC108706636\|UniProtKB=A0A8J1M2A9	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-983158\|UniProtKB=A4II43	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000005978.2\|UniProtKB=A0A3B3HD19	Oryzias latipes	O
DANRE\|Gene=spock3\|UniProtKB=A0A8M3BEW5	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000003489.1\|UniProtKB=W5M6Y0	lepisosteus oculatus	O
BRAFL\|Gene=LOC118410823\|UniProtKB=A0A9J7KRR0	Branchiostoma floridae	O
HUMAN\|HGNC=11220\|UniProtKB=Q14515	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000016260.5\|UniProtKB=H2QPU9	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000015425.3\|UniProtKB=G3RHD3	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000019047.4\|UniProtKB=F6R2E7	Macaca mulatta	O
MOUSE\|MGI=MGI=108110\|UniProtKB=P70663	Mus musculus	O
RAT\|RGD=2531\|UniProtKB=P24054	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000004094.3\|UniProtKB=A0A3Q1LIS3	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000009222.5\|UniProtKB=A0A286ZRX5	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000009280.4\|UniProtKB=F6Z1X6	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000013900.6\|UniProtKB=A0A5F5Y3B8	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845015583.1\|UniProtKB=A0A8I3P261	Canis lupus familiaris	O
ORNAN\|Ensembl=ENSOANG00000015354.4\|UniProtKB=F7BAC2	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010003771.1\|UniProtKB=A0A8V0XK12	Gallus gallus	O
HUMAN\|HGNC=11219\|UniProtKB=P09486	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000017436.5\|UniProtKB=H2QRU3	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000016149.3\|UniProtKB=G3RJ76	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000053367.1\|UniProtKB=G7MVP0	Macaca mulatta	LDO
MOUSE\|MGI=MGI=98373\|UniProtKB=P07214	Mus musculus	LDO
RAT\|RGD=3742\|UniProtKB=P16975	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000014835\|UniProtKB=P13213	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000017082.5\|UniProtKB=A0A5G2R6P1	Sus scrofa	LDO
PIG\|Ensembl=ENSSSCG00005017688\|UniProtKB=P20112	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000013874.4\|UniProtKB=F7APH4	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000006015.5\|UniProtKB=M3W550	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845005166.1\|UniProtKB=A0A8I3MWF4	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000009028.4\|UniProtKB=A0A5F8HE45	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000005112.4\|UniProtKB=F6YAF9	Ornithorhynchus anatinus	LDO
CHICK\|Gene=SPARC\|UniProtKB=P36377	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010014390.1\|UniProtKB=A0A8V0YNY7	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010014980.1\|UniProtKB=A0A8V0YQG5	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000009888.4\|UniProtKB=G1KJH2	Anolis carolinensis	LDO
XENLA\|Gene=sparc.L\|UniProtKB=Q7SZ40	Xenopus laevis	O
XENLA\|Gene=sparc\|UniProtKB=P36378	Xenopus laevis	O
XENLA\|Gene=sparc.S\|UniProtKB=Q7ZXF8	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-1009630\|UniProtKB=Q6P2X6	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000006207.2\|UniProtKB=A4PE74	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-060130-6\|UniProtKB=B3DJ32	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000013522.1\|UniProtKB=W5N7S1	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000011369.2\|UniProtKB=Q6PVV4	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-030131-9\|UniProtKB=Q6IQH0	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000013500.1\|UniProtKB=W5N7N7	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000011666.1\|UniProtKB=W5N131	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000017193.2\|UniProtKB=F6T3M2	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118410956\|UniProtKB=A0A9J7KRU6	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=GeneID_591523\|UniProtKB=A0MT19	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00003893\|UniProtKB=P34714	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00041087\|UniProtKB=A8Y2J4	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00117181\|UniProtKB=A0A2A6BI19	Pristionchus pacificus	LDO
ANOGA\|EnsemblGenome=AGAP000305\|UniProtKB=A0A1S4G8K2	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC000930\|UniProtKB=D6W950	Tribolium castaneum	LDO
DAPPU\|Gene_ORFName=DAPPUDRAFT_48903\|UniProtKB=E9GCX1	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW022231\|UniProtKB=B7QDS2	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG163239\|UniProtKB=T1ETT8	helobdella robusta	LDO
HELRO\|EnsemblGenome=HelroG169094\|UniProtKB=T1F1D9	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g196524\|UniProtKB=A7RFR0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g196727\|UniProtKB=A7RG72	Nematostella vectensis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g245074\|UniProtKB=A7SG90	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g215469\|UniProtKB=A7SPL6	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g238351\|UniProtKB=A7RHQ6	Nematostella vectensis	O