PANTHER Gene Information

Gene Symbol(s):

SCAP

Organism:

Drosophila melanogaster

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Gene Name:

Sterol regulatory element-binding protein cleavage-activating protein

Gene ID:

FBgn0033052

Protein ID:

A1Z6J2

Persistent Id:

PTN000521057

Alternate Ids:

AAF57291(EMBL-CDS)	A1Z6J2(Synonym)
NM_176097(refSeq)	AE013599(EMBL)
FBgn0033052(Ensembl)	28573975(GI)
35529(GeneID)	A1Z6J2_DROME(UniProtKB-ID)
FBpp0085363(Ensembl_PRO)	FBgn0033052(FlyBase)
FBtr0086027(Ensembl_TRS)
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PANTHER Classification

PANTHER Family:	STEROL REGULATORY ELEMENT-BINDING PROTEIN CLEAVAGE-ACTIVATING PROTEIN (PTHR46378)
PANTHER Subfamily:	STEROL REGULATORY ELEMENT-BINDING PROTEIN CLEAVAGE-ACTIVATING PROTEIN (PTHR46378:SF1)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	regulation of lipid biosynthetic process
PANTHER GO-slim Cellular Component:	endoplasmic reticulum membrane membrane protein complex
PANTHER protein class:

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	sterol binding
GO BP Complete:	SREBP signaling pathway, regulation of cholesterol biosynthetic process
GO CC Complete:	endoplasmic reticulum membrane, SREBP-SCAP complex, Golgi membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Metabolism of steroids, Metabolism, Regulation of cholesterol biosynthesis by SREBP (SREBF), Metabolism of lipids

Orthologs

ID	Organism	Type
HUMAN\|HGNC=30634\|UniProtKB=Q12770	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000014872.6\|UniProtKB=K7BC18	Pan troglodytes	LDO
MACMU\|Ensembl=ENSMMUG00000014046.4\|UniProtKB=F7AH97	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2135958\|UniProtKB=Q6GQT6	Mus musculus	LDO
RAT\|RGD=1309378\|UniProtKB=A2RRU4	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000015782.6\|UniProtKB=F1MQ33	Bos taurus	LDO
BOVIN\|Gene=SCAP\|UniProtKB=A6QM06	Bos taurus	LDO
PIG\|Gene=SCAP\|UniProtKB=Q5MNU5	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000026281.4\|UniProtKB=F1SNT3	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000024420.4\|UniProtKB=A0A9L0TEU6	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000015479.6\|UniProtKB=M3WMP1	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845008845.1\|UniProtKB=A0A8I3N9W6	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000014155.4\|UniProtKB=F6X2Y9	Monodelphis domestica	LDO
CHICK\|Ensembl=ENSGALG00010027301.1\|UniProtKB=A0A3Q3ANV4	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000000378.4\|UniProtKB=H9G408	Anolis carolinensis	LDO
XENLA\|Gene=scap\|UniProtKB=A0JPH4	Xenopus laevis	O
XENLA\|Gene=scap.L\|UniProtKB=A0A1L8FUT3	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-996521\|UniProtKB=B0JZG1	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000015864.2\|UniProtKB=A0A3B3HKK1	Oryzias latipes	LDO
DANRE\|Gene=scap\|UniProtKB=A0A8M2B4M5	Danio rerio	LDO
CIOIN\|Ensembl=ENSCING00000008250.3\|UniProtKB=F6QZI8	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118424110\|UniProtKB=A0A9J7LTU6	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC105438074\|UniProtKB=A0A7M7P8I5	Strongylocentrotus purpuratus	LDO
STRPU\|EnsemblGenome=LOC590265\|UniProtKB=A0A7M7NUU9	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00004744\|UniProtKB=Q18968	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00039261\|UniProtKB=A8XXC1	Caenorhabditis briggsae	LDO
ANOGA\|EnsemblGenome=AGAP011336\|UniProtKB=A0A1S4H6D3	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC013456\|UniProtKB=D6WLE2	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_190908\|UniProtKB=E9FU56	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW009641\|UniProtKB=B7Q2Y3	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG189270\|UniProtKB=T1FQW4	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g238428\|UniProtKB=A7RI14	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG55014\|UniProtKB=B3RQJ7	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_32763\|UniProtKB=A9V1K9	Monosiga brevicollis	LDO
NEUCR\|EnsemblGenome=NCU03675\|UniProtKB=Q7S7Y9	Neurospora crassa	LDO
SCLS1\|Gene_ORFName=SS1G_13202\|UniProtKB=A7F6H3	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_07149\|UniProtKB=Q0UM65	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPBC3B9.15c\|UniProtKB=O43043	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_04018\|UniProtKB=B6K5P2	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNC00950\|UniProtKB=Q5KL30	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_02576\|UniProtKB=A0A0D1C6G9	Ustilago maydis	LDO