PANTHER Gene Information   
Gene Symbol(s): Uev1A
Organism: Drosophila melanogaster
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Gene Name: GEO06356p1
Gene ID: FBgn0035601
Protein ID: Q9VRL1
Persistent Id: PTN001176124
Alternate Ids:
NP_647959(refSeq) Q9VRL1_DROME(UniProtKB-ID)
AY060384(EMBL) Q9VRL1(Synonym)
AAL25423(EMBL-CDS) FBpp0311276(Ensembl_PRO)
665409903(GI) FBgn0035601(FlyBase)
FBgn0035601(Ensembl) 38613(GeneID)
FBtr0345026(Ensembl_TRS)
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PANTHER Classification
PANTHER Family: UBIQUITIN-CONJUGATING ENZYME E2 (PTHR24068)
PANTHER Subfamily: GEO06356P1 (PTHR24068:SF143)  
PANTHER GO-slim Molecular Function: ubiquitin conjugating enzyme activity
PANTHER GO-slim Biological Process: postreplication repair
protein K63-linked ubiquitination
PANTHER GO-slim Cellular Component: nucleus
PANTHER protein class: ubiquitin-protein ligase
Pathway Categories: Ubiquitin proteasome pathway
   Ubiquitin-conjugating enzyme E2
Toll receptor signaling pathway
   Ubiquitin-conjugating enzyme E2 variant 1
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: ubiquitin conjugating enzyme binding
GO BP Complete: peptidoglycan recognition protein signaling pathway, protein polyubiquitination, positive regulation of JNK cascade, positive regulation of tumor necrosis factor-mediated signaling pathway, positive regulation of programmed cell death, protein K63-linked ubiquitination, postreplication repair, positive regulation of cell migration
GO CC Complete: nucleus, UBC13-MMS2 complex, ubiquitin conjugating enzyme complex, cytosol
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Toll Like Receptor TLR6:TLR2 Cascade, IRAK1 recruits IKK complex, DNA Repair, Toll Like Receptor 10 (TLR10) Cascade, Toll Like Receptor 3 (TLR3) Cascade, Selective autophagy, Interleukin-1 family signaling, Imd pathway, Aggrephagy, MyD88-independent TLR4 cascade , Toll Like Receptor 7/8 (TLR7/8) Cascade, Macroautophagy, Signaling by Interleukins, Interleukin-1 signaling, DNA Double-Strand Break Repair, IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation, Innate Immune System, TAK1-dependent IKK and NF-kappa-B activation , TRIF(TICAM1)-mediated TLR4 signaling , Class I MHC mediated antigen processing & presentation, Toll Like Receptor 5 (TLR5) Cascade, Activation of the IkappaB kinase complex, KEY:IRD5 dimer:KEY, Toll Like Receptor 9 (TLR9) Cascade, MyD88:MAL(TIRAP) cascade initiated on plasma membrane, Toll Like Receptor TLR1:TLR2 Cascade, Immune System, Antigen processing: Ubiquitination & Proteasome degradation, Autophagy, Adaptive Immune System, DNA Double Strand Break Response, Cytokine Signaling in Immune system, TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation, Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks, MyD88 cascade initiated on plasma membrane, MyD88 dependent cascade initiated on endosome, Drosophila signaling pathways, Toll Like Receptor 4 (TLR4) Cascade, Toll-like Receptor Cascades, Toll Like Receptor 2 (TLR2) Cascade

Orthologs