PANTHER Gene Information

Gene Symbol(s):

PGRP-LC

Organism:

Drosophila melanogaster

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Gene Name:

Peptidoglycan-recognition protein LC

Gene ID:

FBgn0035976

Protein ID:

Q9GNK5

Persistent Id:

PTN000111767

Alternate Ids:

FBgn0035976(FlyBase)	ird7(Synonym)
PGPLC_DROME(UniProtKB-ID)	39063(GeneID)
NM_206308(refSeq)	Q9VSV9(AltAccession)
FBgn0035976(Ensembl)	45551539(GI)
AF500096(EMBL)	ABG02202(EMBL-CDS)
PGRP-LC(Symbol)
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PANTHER Classification

PANTHER Family:	PEPTIDOGLYCAN RECOGNITION PROTEIN (PTHR11022)
PANTHER Subfamily:	PEPTIDOGLYCAN-RECOGNITION PROTEIN LC-RELATED (PTHR11022:SF41)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	defense/immunity protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	peptidoglycan immune receptor activity, peptidoglycan binding, zinc ion binding, lipopolysaccharide immune receptor activity, protein binding
GO BP Complete:	peptidoglycan recognition protein signaling pathway, response to bacterium, regulation of humoral immune response, immune response, defense response to Gram-negative bacterium, regulation of synaptic plasticity, defense response to virus, antibacterial humoral response, positive regulation of antibacterial peptide biosynthetic process, positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria, regulation of melanization defense response
GO CC Complete:	apicolateral plasma membrane, presynapse, membrane, cytoplasmic vesicle, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=30013\|UniProtKB=Q96PD5	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000010624.3\|UniProtKB=H2QFM5	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000000564.3\|UniProtKB=G3SBB6	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000003031.4\|UniProtKB=F6YYJ9	Macaca mulatta	O
MOUSE\|MGI=MGI=1928099\|UniProtKB=Q8VCS0	Mus musculus	O
RAT\|RGD=1359183\|UniProtKB=M0R485	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000012280.6\|UniProtKB=E1BH94	Bos taurus	O
PIG\|Gene=PGLYRP2\|UniProtKB=Q866Y3	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000025560.4\|UniProtKB=A0A5K1UBC7	Sus scrofa	O
FELCA\|Ensembl=ENSFCAG00000013649.5\|UniProtKB=M3WJ85	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845016433.1\|UniProtKB=A0A8I3NUZ6	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000014610.4\|UniProtKB=F6ZE34	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000005133.4\|UniProtKB=F6WGK2	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010003811.1\|UniProtKB=A0A8V0XHG1	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000016557.4\|UniProtKB=A0A803THY7	Anolis carolinensis	O
XENLA\|Gene=pglyrp2.L\|UniProtKB=A0A8J0US95	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-5779913\|UniProtKB=A8QN48	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000016356.2\|UniProtKB=H2MP17	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-071227-2\|UniProtKB=A0A0R4IJX9	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000000315.2\|UniProtKB=H2L3Q8	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-071227-1\|UniProtKB=Q1W1Y3	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000006717.1\|UniProtKB=W5MIA5	lepisosteus oculatus	O
HUMAN\|HGNC=30014\|UniProtKB=Q96LB9	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000001342.3\|UniProtKB=H2Q024	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000000853.3\|UniProtKB=G3QEY4	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000053940.1\|UniProtKB=F6YQC2	Macaca mulatta	O
MOUSE\|MGI=MGI=2685266\|UniProtKB=A1A547	Mus musculus	O
RAT\|RGD=1593164\|UniProtKB=D3ZYV3	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000021443.5\|UniProtKB=E1BJ76	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000027322.4\|UniProtKB=I3LN36	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000011884.4\|UniProtKB=F7BEB8	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000002484.6\|UniProtKB=A0A337SE72	Felis catus	O
HUMAN\|HGNC=30015\|UniProtKB=Q96LB8	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000001344.5\|UniProtKB=H2Q025	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000000856.3\|UniProtKB=G3QEY6	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000006865.4\|UniProtKB=F7F8I2	Macaca mulatta	O
MOUSE\|MGI=MGI=2686324\|UniProtKB=Q0VB07	Mus musculus	O
RAT\|RGD=1308520\|UniProtKB=D4AEA3	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000054765.1\|UniProtKB=A0A3Q1MPE3	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000006587.5\|UniProtKB=F1SFU8	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000011674.3\|UniProtKB=F7ANQ4	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000011704.5\|UniProtKB=M3WFL2	Felis catus	O
MONDO\|Ensembl=ENSMODG00000017413.3\|UniProtKB=F7AJG4	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000050037.1\|UniProtKB=A0A6I8PPD0	Ornithorhynchus anatinus	O
HUMAN\|HGNC=8904\|UniProtKB=O75594	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000011175.6\|UniProtKB=H2QGM5	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000011126.3\|UniProtKB=G3R6A3	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000008742.4\|UniProtKB=H9H398	Macaca mulatta	O
MOUSE\|MGI=MGI=1345092\|UniProtKB=O88593	Mus musculus	O
RAT\|RGD=621429\|UniProtKB=Q9JLN4	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000002635\|UniProtKB=Q8SPP7	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000038688.3\|UniProtKB=A0A286ZI97	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000032321.3\|UniProtKB=A0A5F5Q2T7	Equus caballus	O
HORSE\|Ensembl=ENSECAG00000039739.2\|UniProtKB=F6QB61	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000028691.4\|UniProtKB=M3WZT2	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845004551.1\|UniProtKB=A0A8I3MTX9	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000021527.2\|UniProtKB=F7FSD2	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000049441.1\|UniProtKB=A0A6I8P9R1	Ornithorhynchus anatinus	O
ORNAN\|Ensembl=ENSOANG00000039867.1\|UniProtKB=A0A6I8P284	Ornithorhynchus anatinus	O
ORNAN\|Ensembl=ENSOANG00000030126.2\|UniProtKB=K7EDK3	Ornithorhynchus anatinus	O
ANOCA\|Ensembl=ENSACAG00000000025.4\|UniProtKB=H9G372	Anolis carolinensis	O
XENLA\|Gene=LOC108700665\|UniProtKB=A0A1L8F3H7	Xenopus laevis	O
XENTR\|Ensembl=ENSXETG00000039671\|UniProtKB=A0A803JPG3	Xenopus tropicalis	O
XENLA\|Gene=pglyrp1.S\|UniProtKB=Q5PPZ4	Xenopus laevis	O
XENLA\|Gene=pglyrp1.L\|UniProtKB=A0A8J0TM72	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-491319\|UniProtKB=A0A803JNK5	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000013289.2\|UniProtKB=H2MDK5	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-050419-71\|UniProtKB=Q1W1Y2	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000014823.1\|UniProtKB=W5NC92	lepisosteus oculatus	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_76871\|UniProtKB=C3YN89	Branchiostoma floridae	O
BRAFL\|Gene=LOC118425176\|UniProtKB=A0A9J7N4M1	Branchiostoma floridae	O
BRAFL\|Gene=LOC118426144\|UniProtKB=A0A9J7LZJ6	Branchiostoma floridae	O
BRAFL\|Gene=LOC118406003\|UniProtKB=A0A9J7HLF5	Branchiostoma floridae	O
BRAFL\|Gene=LOC118431182\|UniProtKB=A0A9J7NC30	Branchiostoma floridae	O
BRAFL\|Gene=LOC118405853\|UniProtKB=A0A9J7HKZ7	Branchiostoma floridae	O
BRAFL\|Gene=LOC118416065\|UniProtKB=A0A9J7MRX9	Branchiostoma floridae	O
BRAFL\|Gene=LOC118422467\|UniProtKB=A0A9J7LPE7	Branchiostoma floridae	O
BRAFL\|Gene=LOC118427931\|UniProtKB=A0A9J7M5L9	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC100892590\|UniProtKB=A0A7M7PEC7	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115919963\|UniProtKB=A0A7M7N395	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC591777\|UniProtKB=A0A7M7STK5	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC764572\|UniProtKB=A0A7M7N4R5	Strongylocentrotus purpuratus	O
ANOGA\|EnsemblGenome=AGAP005203\|UniProtKB=A7UTA1	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC010508\|UniProtKB=D6WE12	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC002790\|UniProtKB=D6WIN7	Tribolium castaneum	O
IXOSC\|EnsemblGenome=ISCW024689\|UniProtKB=B7Q5J1	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW004389\|UniProtKB=B7PER7	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW022212\|UniProtKB=B7QC27	Ixodes scapularis	O