PANTHER Gene Information

Gene Symbol(s):

eap

Organism:

Drosophila melanogaster

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Gene Name:

L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase

Gene ID:

FBgn0052099

Protein ID:

Q8SXB3

Persistent Id:

PTN000259263

Alternate Ids:

FBgn0052099(FlyBase)	317852(GeneID)
FBtr0076000(Ensembl_TRS)	FBpp0075732(Ensembl_PRO)
AY094706(EMBL)	Q8SXB3(Synonym)
FBgn0052099(Ensembl)	AAN12253(EMBL-CDS)
NP_729788(refSeq)	24663173(GI)
Q8SXB3_DROME(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	PHOSPHOPANTETHEINE TRANSFERASE (PTHR12215)
PANTHER Subfamily:	L-AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE-PHOSPHOPANTETHEINYL TRANSFERASE (PTHR12215:SF10)
PANTHER GO-slim Molecular Function:	transferase activity, transferring phosphorus-containing groups
PANTHER GO-slim Biological Process:	lysine biosynthetic process
PANTHER GO-slim Cellular Component:	cytosol
PANTHER protein class:	transferase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	magnesium ion binding, holo-[acyl-carrier-protein] synthase activity
GO BP Complete:	lysine biosynthetic process via aminoadipic acid
GO CC Complete:	cytosol

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Metabolism of vitamins and cofactors, Metabolism, Vitamin B5 (pantothenate) metabolism, Metabolism of water-soluble vitamins and cofactors

Orthologs

ID	Organism	Type
HUMAN\|HGNC=14235\|UniProtKB=Q9NRN7	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000004236.4\|UniProtKB=H2Q4P2	Pan troglodytes	LDO
MACMU\|Ensembl=ENSMMUG00000010990.3\|UniProtKB=F7GS66	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1914868\|UniProtKB=Q9CQF6	Mus musculus	LDO
RAT\|RGD=1311360\|UniProtKB=B2RYJ4	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000052263.1\|UniProtKB=G3MZI2	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000012279.5\|UniProtKB=A0A3Q1LL63	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00005033104.1\|UniProtKB=F1SV35	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000013032.4\|UniProtKB=A0A5F5PTV0	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000031934.4\|UniProtKB=M3WRD0	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845004003.1\|UniProtKB=A0A8I3MUX5	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000014729.4\|UniProtKB=F6ZCR9	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000010465.4\|UniProtKB=A0A6I8PI82	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010005177.1\|UniProtKB=A0A8V0XPN9	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000011121.4\|UniProtKB=G1KKV6	Anolis carolinensis	LDO
XENLA\|Gene=aasdhppt.S\|UniProtKB=A0A8J0UGZ7	Xenopus laevis	LDO
XENLA\|Gene=aasdhppt\|UniProtKB=Q6DJH2	Xenopus laevis	LDO
XENTR\|Ensembl=ENSXETG00000032901\|UniProtKB=A0A6I8PQC4	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000010535.2\|UniProtKB=H2M447	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-050913-36\|UniProtKB=Q4V8T8	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000006918.1\|UniProtKB=W5MJ26	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000005262.3\|UniProtKB=F6V9L7	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118419058\|UniProtKB=A0A9J7LFM8	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC581654\|UniProtKB=A0A7M7SWS5	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00020215\|UniProtKB=Q22171	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00029977\|UniProtKB=A8X5U9	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00012142\|UniProtKB=Q22856	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00041856\|UniProtKB=A8Y3R2	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00304962\|UniProtKB=A0A8R1V5X1	Pristionchus pacificus	LDO
ANOGA\|EnsemblGenome=AGAP007546\|UniProtKB=A7URA5	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC011251\|UniProtKB=D6X3H4	Tribolium castaneum	LDO
IXOSC\|EnsemblGenome=ISCW020110\|UniProtKB=A0A1S4LW51	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG133824\|UniProtKB=T1EI26	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g228405\|UniProtKB=A7RNF6	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG33740\|UniProtKB=B3SD54	Trichoplax adhaerens	LDO
YEAST\|SGD=S000003122\|UniProtKB=P50113	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AGR382W\|UniProtKB=Q74Z24	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000182911\|UniProtKB=Q59N08	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_E09306g\|UniProtKB=Q6C6I2	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_06140\|UniProtKB=G5EB87	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_2G08590\|UniProtKB=Q4X1W0	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU00581\|UniProtKB=Q7SI69	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_02731\|UniProtKB=A7EBP5	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_09596\|UniProtKB=Q0UF68	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPAC17C9.02c\|UniProtKB=Q10474	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_01955\|UniProtKB=B6JZC6	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNG03935\|UniProtKB=A0A0S2M5M3	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_03832\|UniProtKB=A0A0D1E0K2	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_16258\|UniProtKB=E3L083	Puccinia graminis	LDO
PUCGT\|EnsemblGenome=PGTG_03776\|UniProtKB=E3K0J5	Puccinia graminis	LDO
DICDI\|dictyBase=DDB_G0285927\|UniProtKB=Q54MI2	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_148072\|UniProtKB=F0ZA60	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_20_0830\|UniProtKB=Q4QCW3	Leishmania major	LDO
PHYRM\|Gene=H3GI69_PHYRM\|UniProtKB=H3GI69	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_07g323750v5\|UniProtKB=A0A2K3DJ76	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00095p00076530\|UniProtKB=W1NRG7	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_44G01550\|UniProtKB=A0A0K9P3F4	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma08_g09200\|UniProtKB=A0A804K4L1	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_026744mg\|UniProtKB=K3ZJJ1	Setaria italica	O
SETIT\|EnsemblGenome=SETIT_010769mg\|UniProtKB=K3Y977	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3005G025300\|UniProtKB=C5Y426	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb196200\|UniProtKB=K7UM39	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os12g0133400\|UniProtKB=Q2QY38	Oryza sativa	O
ORYSJ\|EnsemblGenome=Os11g0136500\|UniProtKB=A0A0P0XYJ2	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_4g26330v3\|UniProtKB=I1INR6	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.4HG0356720\|UniProtKB=A0A8I6YF96	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS4D02G125600\|UniProtKB=A0A3B6JIN1	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS4B02G130400\|UniProtKB=A0A3B6IMU8	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4A02G187800\|UniProtKB=A0A3B6HX18	Triticum aestivum	LDO
SPIOL\|Gene=LOC110793355\|UniProtKB=A0A9R0ITC9	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr07g0300321\|UniProtKB=A0A251UBQ3	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C500293080\|UniProtKB=A0A9R1X8L6	Lactuca sativa	O
LACSA\|Gene_ORFName=LSAT_V11C200088750\|UniProtKB=A0A9R1XSA8	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a010926mg\|UniProtKB=A0A022RAB2	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_29713\|UniProtKB=A0A2G2Y6D7	Capsicum annuum	LDO
SOLLC\|EnsemblGenome=Solyc11g006930.2\|UniProtKB=A0A3Q7JHZ3	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107818355\|UniProtKB=A0A1S4CFU5	Nicotiana tabacum	O
TOBAC\|Gene=LOC107823737\|UniProtKB=A0A1S4CY18	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi13g00922\|UniProtKB=D7SSF6	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_J00256\|UniProtKB=A0A059A9M5	Eucalyptus grandis	LDO
GOSHI\|Gene=LOC107934809\|UniProtKB=A0A1U8M7S2	Gossypium hirsutum	O
GOSHI\|Gene=LOC107927324\|UniProtKB=A0A1U8LGX0	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_013483\|UniProtKB=A0A061FWF9	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g023684mg\|UniProtKB=A0A067DN32	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_010G238500v3\|UniProtKB=B9HVX4	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_03G085100\|UniProtKB=A0A2C9W5S0	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1087090\|UniProtKB=B9SG80	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_02G164100\|UniProtKB=A0A0R0L540	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_15G117500\|UniProtKB=K7MAV4	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_1g050425\|UniProtKB=A0A072VII8	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr05_04360\|UniProtKB=A0A2I4GQ85	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_5G614660\|UniProtKB=A0A0A0KRD2	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_2G075500\|UniProtKB=A0A251QCQ6	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_113118\|UniProtKB=D8SBI5	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_105813\|UniProtKB=D8S0V8	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c5_16220\|UniProtKB=A0A2K1KJZ7	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0020s0170\|UniProtKB=A0A2R6XEL8	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_007750020\|UniProtKB=A0A1Y1IRL1	Klebsormidium nitens	LDO
CLOBH\|Gene_OrderedLocusName=CBO2592\|UniProtKB=A5I523	Clostridium botulinum	LDO
STRR6\|EnsemblGenome=spr1541\|UniProtKB=P0A2W7	Streptococcus pneumoniae	LDO
STAA8\|EnsemblGenome=SAOUHSC_00145\|UniProtKB=Q2G1H8	Staphylococcus aureus	LDO
BACSU\|EnsemblGenome=BSU_04620\|UniProtKB=P96618	Bacillus subtilis	LDO
BACCR\|EnsemblGenome=BC_2311\|UniProtKB=Q81DP5	Bacillus cereus	O
BACCR\|EnsemblGenome=BC_0262\|UniProtKB=Q81IT7	Bacillus cereus	LDO
THEMA\|EnsemblGenome=TM_0692\|UniProtKB=Q9WZF6	Thermotoga maritima	LDO
GLOVI\|Gene=Q7NJ81_GLOVI\|UniProtKB=Q7NJ81	Gloeobacter violaceus	O
GLOVI\|Gene=Q7NCX5_GLOVI\|UniProtKB=Q7NCX5	Gloeobacter violaceus	LDO
SYNY3\|EnsemblGenome=BAA10326\|UniProtKB=Q55185	Synechocystis	LDO
RHOBA\|EnsemblGenome=RB1840\|UniProtKB=Q7UWR7	Rhodopirellula baltica	LDO
BRADU\|Gene=Q89T14_BRADU\|UniProtKB=Q89T14	Bradyrhizobium diazoefficiens	LDO
COXBU\|EnsemblGenome=CBU_0221\|UniProtKB=Q83ET9	Coxiella burnetii	LDO
HAEIN\|EnsemblGenome=HI_0152\|UniProtKB=P43954	Haemophilus influenzae	LDO
SHEON\|Gene_OrderedLocusName=SO_1604\|UniProtKB=Q8EGJ8	Shewanella oneidensis	LDO
XANCP\|EnsemblGenome=XCC4043\|UniProtKB=Q8P3M8	Xanthomonas campestris	LDO
SALTY\|EnsemblGenome=STM3849\|UniProtKB=Q7CPE8	Salmonella typhimurium	O
ECOLI\|EnsemblGenome=BAE77576\|UniProtKB=P0ADM8	Escherichia coli	O
SALTY\|EnsemblGenome=STM3583\|UniProtKB=Q8ZLE2	Salmonella typhimurium	LDO
ECOLI\|EnsemblGenome=BAE77818\|UniProtKB=P37623	Escherichia coli	LDO